Abstract: The present invention provides: a marker for determining critical stage kidney disease by using an indicator value based on the amount of D-alanine in the blood or the amount of D-alanine and L-alanine therein; a blood analysis method which uses said marker for patients undergoing surgery or intensive care; and a blood analysis system for determining critical stage kidney disease in patients undergoing surgery or intensive care.

Abstract: The present invention pertains to a pharmaceutical composition for the prevention or treatment of kidney disease, an inflammation inhibitor for the kidneys, an inflammatory cell death inhibitor for the kidneys, or a food for the prevention or improvement of kidney disease, that include D-serine or a derivative thereof. In addition, the present invention pertains to the use of D-serine or a derivative thereof, for the production of a pharmaceutical composition for the prevention or treatment of kidney disease.

Abstract: The present invention pertains to a pharmaceutical composition for the prevention or treatment of kidney disease, a kidney inflammation inhibitor, an inflammatory cell death inhibitor for the kidneys, or a food for the prevention or improvement of kidney disease, that include D-alanine or a derivative thereof. In addition, the present invention pertains to the use of D-alanine or a derivative thereof, for the production of a pharmaceutical composition for the prevention or treatment of kidney disease.

Abstract: A method for manufacturing a diamond substrate, including: a first step of preparing patterned diamond on a foundation surface, a second step of growing diamond from the patterned diamond prepared in the first step to form the diamond in a pattern gap of the patterned diamond prepared in the first step, a third step of removing the patterned diamond prepared in the first step to form a patterned diamond composed of the diamond formed in the second step, and a fourth step of growing diamond from the patterned diamond formed in the third step to form the diamond in a pattern gap of the patterned diamond formed in the third step. There can be provided a method for manufacturing a diamond substrate which can sufficiently suppress dislocation defects, a high-quality diamond substrate, and a freestanding diamond substrate.

Abstract: It is an object of the present invention to obtain a novel composite material excellent in terms of flexibility and thermoformability from a lignocellulosic biomass as a raw material. A composite material, in which some hydroxy groups of a lignocellulosic biomass are esterified, which is characterized in that the esterified portion has short-chain acyl groups containing 2 to 4 carbon atoms and long-chain acyl groups containing 3 to 18 carbon atoms.

Abstract: An engine mount control apparatus that is an active noise vibration control apparatus according to the present disclosure is characterized by being provided with a housing that has an outer core, an inner core that is disposed inside the outer core, and an electromagnetic coil that is positioned between the outer core and the inner core and by a portion between the outer core and the inner core being filled with a magneto-rheological elastomer containing magnetic particles. The present disclosure enables the maintenance of good static load support performance.

Abstract: A method for manufacturing diamond substrate of using source gas containing hydrocarbon gas and hydrogen gas to form diamond crystal on an underlying substrate by CVD method, to form a diamond crystal layer having nitrogen-vacancy centers in at least part of the diamond crystal, nitrogen or nitride gas is mixed in the source gas, wherein the source gas is: 0.005 volume % or more and 6.000 volume % or less of the hydrocarbon gas; 93.500 volume % or more and less than 99.995 volume % of the hydrogen gas; and 5.0×10?5 volume % or more and 5.0×10?1 volume % or less of the nitrogen gas or the nitride gas, and the diamond crystal layer having the nitrogen-vacancy centers is formed. A method for manufacturing a diamond substrate to form an underlying substrate, a diamond crystal having a dense nitrogen-vacancy centers (NVCs) with an orientation of NV axis by performing the CVD.

Abstract: The present invention provides a miniaturized hemagglutinin complex protein having function inhibitory activity against E-cadherin, wherein (a) all or a part of at least HA1 subcomponent, and/or a part of HA3 subcomponent are/is deleted, (b) regions in HA2 and HA3 subcomponents that contribute to binding with E-cadherin are present, and (c) the HA3 subcomponent is derived from Clostridium botulinum type A or type B, and an E-cadherin function inhibitor containing the hemagglutinin complex protein.

Abstract: A measuring device includes a stimulation instructing unit and an estimating unit. The stimulation instructing unit is configured to instruct a stimulating device to generate a plurality of stimulations corresponding to at least three fiducial points of brain anatomy data, the at least three fiducial points having been defined in the brain anatomy data. The estimating unit is configured to estimate, based on sensor output signals output from sensors configured to measure a brain activity signal of a subject who is a target to be measured, parts where brain activities occur due to the plurality of stimulations.

Abstract: A power generation element uses an inverse magnetostrictive effect and includes: a frame yoke made of a magnetic material and having a bent part for forming a closed magnetic circuit, a magnetic part formed in a part of the frame yoke, a magnetostrictive plate made of a magnetostrictive material, a coil, and magnets. The magnetic part has rigidity and geometry for applying a uniform compressive force or tensile force to the magnetostrictive plate and is magnetically saturated by magnetic biases of the magnets. The magnetostrictive plate is attached to the frame yoke so as to be parallel to the magnetic part. The coil is wound around a parallel beam part including the magnetostrictive plate and the magnetic part and/or around the frame yoke. An application of an external force causes the magnetostrictive plate to be extended and compressed and causes the generation of electricity.

Abstract: A surface shape variable device which comprises a board-like member comprising a plurality of strip elements capable of being elastically morphed which extend in parallel along a plane; and morphing control devises which elastically morph the strip elements due to buckling and the like toward a direction traversing the plane by applying stress to at least a part of the strip elements, wherein the strip elements are woven into a woven fabric-like state and extend intersecting with each other.

Abstract: Provided are a polyolefin-based resin composition having excellent antistatic performance, and a polyolefin-based resin film formed using the composition. More specifically, a polyolefin-based resin composition comprising a polyolefin-based resin, a polyalkylene carbonate resin, and a metal salt having a melting point higher than 100° C. is provided. Also provided is a polyolefin-based resin film formed using the polyolefin-based resin composition, the film being stretched at least uniaxially.

Abstract: The present invention provides a polyolefin-based resin composition that has improved resilience while maintaining mechanical strength and stretching properties, as well as a molded article and a polyolefin-based resin film formed from this composition. The polyolefin-based resin composition comprises a polyolefin-based resin, a polyalkylene carbonate resin, and an ionic liquid. The polyolefin-based resin film of the present invention is formed by molding the polyolefin-based resin composition and is stretched at least in a monoaxial direction.

Abstract: An activity amount calculation system includes a plurality of detection units and an activity amount calculation device. The plurality of detection units detect a resident and output detection signals when the resident passes through doorways of a plurality of rooms. The calculation device includes a calculation unit and a summation unit. Upon detection of the resident by the detection units, the calculation unit calculates an activity amount of the resident based on relationships between detection units and reference activity amounts. The summation unit repeatedly calculates a total activity amount of the resident in a predetermined period by summing activity amounts calculated by the calculation unit.

Abstract: An engine mount control apparatus that is an active noise vibration control apparatus according to the present disclosure is characterized by being provided with a housing that has an outer core, an inner core that is disposed inside the outer core, and an electromagnetic coil that is positioned between the outer core and the inner core and by a portion between the outer core and the inner core being filled with a magneto-rheological elastomer containing magnetic particles. The present disclosure enables the maintenance of good static load support performance.

Abstract: This dynamic damper is provided with a movable part that can be moved by external input, and an excitation coil for generating a magnetic field of an intensity corresponding to a supplied electric current. The movable part is configured to include: first and second magnetic cores in which magnetic paths, which are pathways for the magnetic field generated by the excitation coil, are configured as annular closed magnetic paths; and a magnetic viscous elastomer of which the viscous properties change in accordance with the size of the magnetic field generated by the excitation coil. The magnetic viscous elastomer is arranged so as link at least one location in the first and second magnetic cores and constitutes a closed magnetic path.

Abstract: Provided are an organoid having a metastatic property when transplanted into an immunocompetent non-human animal of the same species, a cell strain having a metastatic property when transplanted into an immunocompetent non-human animal of the same species, and a non-human animal including the organoid or the cell strain.

Abstract: A method for manufacturing a copper alloy of the present invention is a method for manufacturing a Cu—Ni—Sn-based copper alloy and includes: a first aging treatment step of performing an aging treatment in a temperature range of 300° C. to 500° C. using a solution treated material; an inter-aging processing step of performing cold working after the first aging treatment step; and a second aging treatment step of performing an aging treatment in a temperature range of 300° C. to 500° C. after the inter-aging processing step. In the first aging treatment step, a peak aging treatment is preferably performed. In addition, in the second aging treatment step, the aging treatment is preferably performed for a short period as compared to that of the aging treatment in the first aging treatment step. In the inter-aging processing step, cold working is preferably performed at a processing rate of more than 60% to 99%.

Abstract: An object is to provide a method for producing a polysaccharide derivative without using a catalyst, a cocatalyst, or an active compound by esterification, etherification, or the like, from a polysaccharide such as cellulose as a source material, while maintaining a high molecular weight. Another object is to provide a method for producing a cellulose derivative in a separated condition directly from biomass containing lignocellulose. A method for producing a polysaccharide derivative of the present invention is characterized in that a reaction is carried out in a mixture comprising: a source material comprising a polysaccharide; an ionic liquid for which the pKa of a conjugate acid of an anion in DMSO is 12 to 19 and which is capable of producing a carbene; and a chain or cyclic ester compound or an epoxy compound. Preferably as a source material containing a polysaccharide, a biomass source material containing lignocellulose is used.

Abstract: A power generation element uses an inverse magnetostrictive effect and includes: a frame yoke made of a magnetic material and having a bent part for forming a closed magnetic circuit, a magnetic part formed in a part of the frame yoke, a magnetostrictive plate made of a magnetostrictive material, a coil, and magnets. The magnetic part has rigidity and geometry for applying a uniform compressive force or tensile force to the magnetostrictive plate and is magnetically saturated by magnetic biases of the magnets. The magnetostrictive plate is attached to the frame yoke so as to be parallel to the magnetic part. The coil is wound around a parallel beam part including the magnetostrictive plate and the magnetic part and/or around the frame yoke. An application of an external force causes the magnetostrictive plate to be extended and compressed and causes the generation of electricity.