Patents Assigned to National University Corporation Nagoya Institute of Technology
  • Publication number: 20240252714
    Abstract: A bone-regeneration material comprising a biodegradable fiber produced using an electrospinning process, wherein the biodegradable fiber comprises 30 to 50 wt % of PLLGA resin and 70 to 50 wt % of ?-TCP fine particles substantially uniformly dispersed in the PLLGA resin without forming aggregates, wherein the ?-TCP fine particles are not chemically bonded to the PLLGA resin, and surroundings of the ?-TCP fine particles are covered by the PLLGA resin so that the ?-TCP fine particles are not separated from the biodegradable fiber during a formation of the fiber, and wherein the bone-regeneration material is sterilized by using radiation sterilization with gamma ray.
    Type: Application
    Filed: April 9, 2024
    Publication date: August 1, 2024
    Applicants: NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY, ORTHOREBIRTH CO., LTD.
    Inventors: Toshihiro Kasuga, Yasutoshi Nishikawa
  • Patent number: 11969521
    Abstract: A bone-regeneration material that contains calcium phosphate particles in a biodegradable fiber containing PLGA by using electrospinning. A PLGA resin is heated in a kneader to soften until the viscosity of the resin becomes 102 to 107 Pa·s. A powder of calcium phosphate fine particles is added and mixed with the softened PLGA resin, while the blade of the kneader rotates. The mixture is kneaded by applying thermal and mechanical energy to the mixture through the continuous rotation of the blade of the kneader in the heated state, and aggregations of the calcium phosphate fine particles are disintegrated to prepare a composite in which the calcium phosphate fine particles are dispersed in the PLGA resin. The composite is dissolved in a solvent to prepare a spinning solution. Electrospinning is performed on the spinning solution to manufacture biodegradable fibers having therein the calcium phosphate fine particles substantially uniformly dispersed.
    Type: Grant
    Filed: April 3, 2020
    Date of Patent: April 30, 2024
    Assignees: NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY, ORTHOREBIRTH CO., LTD.
    Inventors: Toshihiro Kasuga, Yasutoshi Nishikawa
  • Patent number: 10814000
    Abstract: A guided bone regeneration material is disclosed. The guided bone regeneration material includes biodegradable fibers produced by an electrospinning method. The biodegradable fibers produced by the method include a silicon-releasing calcium carbonate and a biodegradable polymer. The silicon-releasing calcium carbonate is a composite of siloxane and calcium carbonate of vaterite phase. The biodegradable fibers may be coated with apatite. When the guided bone regeneration material is immersed in a neutral aqueous solution, silicon species ions are eluted from the calcium carbonate. The guided bone regeneration material excels in bone reconstruction ability.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: October 27, 2020
    Assignees: NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY, ORTHOREBIRTH CO., LTD., YAMAHACHI DENTAL MFG., CO., YABASHI INDUSTRIES, CO., LTD.
    Inventors: Toshihiro Kasuga, Yoshio Ota, Takashi Wakita
  • Patent number: 10807541
    Abstract: In the surface structure of an article 7 according to the present invention, a plurality of convex portions 11 are so disposed on a surface 9 as to have intervals relative to each other and a plurality of fine convex portions 21 having a diameter d and a height h smaller than those of the concave portion 11 are formed on the surface of at least the edge portion 15 of the concave portion 11. By this, when a hand touches the surface 9 of the article 7, the proper number of convex portions 21 abut on a linear object 25 constituting a fingerprint 23 of a hand's finger, to thereby allow the human being to obtain a delicate-and-soft touch feeling.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: October 20, 2020
    Assignees: NISSAN MOTOR CO., LTD., NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY
    Inventors: Akane Ban, Makoto Tamuraya, Takashi Takeuchi, Yeon-Yi Kang, Hideo Fujimoto, Akihito Sano, Hiromi Mochiyama, Naoyuki Takesue, Yoshihiro Tanaka
  • Publication number: 20200289703
    Abstract: A bone-regeneration material that contains calcium phosphate particles in a biodegradable fiber containing PLGA by using electrospinning. A PLGA resin is heated in a kneader to soften until the viscosity of the resin becomes 102 to 107 Pa·s. A powder of calcium phosphate fine particles is added and mixed with the softened PLGA resin, while the blade of the kneader rotates. The mixture is kneaded by applying thermal and mechanical energy to the mixture through the continuous rotation of the blade of the kneader in the heated state, and aggregations of the calcium phosphate fine particles are disintegrated to prepare a composite in which the calcium phosphate fine particles are dispersed in the PLGA resin. The composite is dissolved in a solvent to prepare a spinning solution. Electrospinning is performed on the spinning solution to manufacture biodegradable fibers having therein the calcium phosphate fine particles substantially uniformly dispersed.
    Type: Application
    Filed: April 3, 2020
    Publication date: September 17, 2020
    Applicants: NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY, ORTHOREBIRTH CO., LTD.
    Inventors: Toshihiro Kasuga, Yasutoshi Nishikawa
  • Patent number: 10646616
    Abstract: A bone-regeneration material that contains calcium phosphate particles in biodegradable fibers of PLGA manufactured by electrospinning. A PLGA resin is heated in a kneader until the resin viscosity becomes 102 to 107 Pa·s. A powder of calcium phosphate fine particles is added while the blade is rotated. The mixture is kneaded by continuous rotation of the blade in the heated state to disperse the calcium phosphate fine particles to obtain a composite having calcium phosphate fine particles dispersed in the PLGA resin. The composite is dissolved by a solvent, and the PLGA resin is completely dissolved by agitation for a prescribed duration to prepare a spinning solution in which the calcium phosphate fine particles are dispersed. Electrospinning is performed on the spinning solution to manufacture biodegradable fibers having therein the calcium phosphate fine particles substantially uniformly dispersed.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: May 12, 2020
    Assignees: National University Corporation Nagoya Institute of Technology, Orthorebirth Co., Ltd.
    Inventors: Toshihiro Kasuga, Yasutoshi Nishikawa
  • Patent number: 10545172
    Abstract: A cantilever used in a scanning probe microscope includes a supporting section, a lever section, and a protrusion section, which is a probe. A crystalline carbon composite layer including a crystalline carbon nanomaterial and a metal material, a melting point of which is 420° C. or lower, is deposited on a distal end portion of the protrusion section.
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: January 28, 2020
    Assignees: National University Corporation Nagoya Institute of Technology, OLYMPUS CORPORATION
    Inventors: Masaki Tanemura, Riteshkumar Ratneshkumar Vishwakarma, Mohamad Saufi Bin Rosmi, Yazid Bin Yaakob, Yuji Wakamatsu, Masashi Kitazawa
  • Patent number: 10433892
    Abstract: Provided is a material for preventing bone cement from leaking out from bone during packing of the bone cement into a bone fracture site. The bone cement can be prevented from leaking out from the bone by employing a three-dimensional structure produced from a material containing a polyhydroxyalkanoate, when packing the bone cement into the bone fracture site.
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: October 8, 2019
    Assignees: National University Corporation Nagoya University, National University Corporation Nagoya Institute of Technology
    Inventors: Hitoshi Hirata, Takanobu Nishizuka, Tadahiro Natsume, Toshihiro Kasuga
  • Patent number: 10203354
    Abstract: The present invention provides a cantilever for a scanning type probe microscope, the cantilever including a support portion, a lever portion extending from the support portion, a protrusion portion formed on a free end side of the lever portion, an apex angle of the protrusion portion being an acute angle, and a probe in which a fine wire formed at a distal end of the protrusion portion is coated with a functional film, and a major axis/minor axis ratio of a cross-sectional shape of the probe is smaller than a major axis/minor axis ratio of a cross-sectional shape of the fine wire.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: February 12, 2019
    Assignees: National University Corporation Nagoya Institute of Technology, OLYMPUS CORPORATION
    Inventors: Masashi Kitazawa, Michitsugu Arima, Masaki Tanemura
  • Publication number: 20190018042
    Abstract: A cantilever used in a scanning probe microscope includes a supporting section, a lever section, and a protrusion section, which is a probe. A crystalline carbon composite layer including a crystalline carbon nanomaterial and a metal material, a melting point of which is 420° C. or lower, is deposited on a distal end portion of the protrusion section.
    Type: Application
    Filed: September 5, 2018
    Publication date: January 17, 2019
    Applicants: NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY, OLYMPUS CORPORATION
    Inventors: Masaki TANEMURA, Riteshkumar Ratneshkumar VISHWAKARMA, Mohamad Saufi BIN ROSMI, Yazid BIN YAAKOB, Yuji WAKAMATSU, Masashi KITAZAWA
  • Publication number: 20180369382
    Abstract: A guided bone regeneration material is disclosed. The guided bone regeneration material includes biodegradable fibers produced by an electrospinning method. The biodegradable fibers produced by the method include a silicon-releasing calcium carbonate and a biodegradable polymer. The silicon-releasing calcium carbonate is a composite of siloxane and calcium carbonate of vaterite phase. The biodegradable fibers may be coated with apatite. When the guided bone regeneration material is immersed in a neutral aqueous solution, silicon species ions are eluted from the calcium carbonate. The guided bone regeneration material excels in bone reconstruction ability.
    Type: Application
    Filed: August 31, 2018
    Publication date: December 27, 2018
    Applicants: NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY, YABASHI INDUSTRIES, CO., LTD., YAMAHACHI DENTAL MFG., CO., ORTHOREBIRTH CO., LTD.
    Inventors: Toshihiro Kasuga, Yoshio Ota, Takashi Wakita
  • Patent number: 10159737
    Abstract: A guided bone regeneration material is disclosed. The guided bone regeneration material includes biodegradable fibers produced by an electrospinning method. The biodegradable fibers produced by the method include a silicon-releasing calcium carbonate and a biodegradable polymer. The silicon-releasing calcium carbonate is a composite of siloxane and calcium carbonate of vaterite phase. The biodegradable fibers may be coated with apatite. When the guided bone regeneration material is immersed in a neutral aqueous solution, silicon species ions are eluted from the calcium carbonate. The guided bone regeneration material excels in bone reconstruction ability.
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: December 25, 2018
    Assignees: NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY, YABASHI INDUSTRIES CO., LTD., YAMAHACHI DENTAL MFG., CO., ORTHOREBIRTH CO., LTD.
    Inventors: Toshihiro Kasuga, Yoshio Ota, Takashi Wakita
  • Patent number: 10092650
    Abstract: A guided bone regeneration material is disclosed. The guided bone regeneration material includes biodegradable fibers produced by an electrospinning method. The biodegradable fibers produced by the method include a silicon-releasing calcium carbonate and a biodegradable polymer. The silicon-releasing calcium carbonate is a composite of siloxane and calcium carbonate of vaterite phase. The biodegradable fibers may be coated with apatite. When the guided bone regeneration material is immersed in a neutral aqueous solution, silicon species ions are eluted from the calcium carbonate. The guided bone regeneration material excels in bone reconstruction ability.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: October 9, 2018
    Assignees: National University Corporation, Nagoya Institute of Technology, Yabashi Industries Co., LTD, Yamahachi Dental Mfg., Co, Orthorebirth Co. Ltd.
    Inventors: Toshihiro Kasuga, Yoshio Ota, Takashi Wakita
  • Publication number: 20180280569
    Abstract: A bone-regeneration material that contains calcium phosphate particles in biodegradable fibers of PLGA manufactured by electrospinning. A PLGA resin is heated in a kneader until the resin viscosity becomes 102 to 107 Pa·s. A powder of calcium phosphate fine particles is added while the blade is rotated. The mixture is kneaded by continuous rotation of the blade in the heated state to disperse the calcium phosphate fine particles to obtain a composite having calcium phosphate fine particles dispersed in the PLGA resin. The composite is dissolved by a solvent, and the PLGA resin is completely dissolved by agitation for a prescribed duration to prepare a spinning solution in which the calcium phosphate fine particles are dispersed. Electrospinning is performed on the spinning solution to manufacture biodegradable fibers having therein the calcium phosphate fine particles substantially uniformly dispersed.
    Type: Application
    Filed: April 28, 2017
    Publication date: October 4, 2018
    Applicants: NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY, ORTHOREBIRTH CO.LTD.
    Inventors: Toshihiro Kasuga, Yasutoshi Nishikawa
  • Publication number: 20180021479
    Abstract: Rebuilding a defected bone by activating the innate self-regeneration ability of bone requires a considerably long period of time. The purpose of the present invention is to provide a bone defect filling material that initiates a bone rebuilding activity as quickly as possible after implantation and thereafter remains in the defect to continue promoting bone formation activity until sufficient bone formation has been achieved for the rebuilding of the defect. The present invention provides a cotton-like bone defect filling material comprising biodegradable fibers produced by electrospinning. The biodegradable fibers contain 40-60 wt % of calcium phosphate particles and 10 wt % or more of silicon-releasing calcium carbonate particles, with the remainder containing 30 wt % or more of poly(L-lactic acid) polymer, and the amount of the poly(L-lactic acid) polymer that is non-crystalline is 75-98%.
    Type: Application
    Filed: August 25, 2017
    Publication date: January 25, 2018
    Applicants: ORTHOREBIRTH CO., LTD., NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY
    Inventors: Masashi Makita, Toshihiro Kasuga
  • Patent number: 9783229
    Abstract: A control system calculates inputs to a control target that has m inputs and n outputs (m=n, each of m and n is a natural number that is more than one), while designating a plurality of combinations of the inputs and the outputs. A feedback controller calculates, with respect to each designated combination, a control input to a non-interference controller based on a difference between a target value and a current value of the control quantity to make the current value follow the target value. The non-interference controller executes, with respect to each designated combination, a non-interference control to reduce influence due to mutual interference between n control quantities. This reduces the number of combinations of the inputs and the outputs, the combinations whose mutual interference needs considering; thereby, the non-interference control may be easily achieved.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: October 10, 2017
    Assignees: DENSO CORPORATION, NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY
    Inventors: Yasuhiko Mukai, Yoshifumi Morita, Hiroyuki Ukai, Makoto Iwasaki, Takeshi Wada
  • Patent number: 9595382
    Abstract: A resonance coil includes plural unit coils where directions of magnetic fields which are formed by flowing of electric current are the same, in which the plural unit coils are arranged around a coil center line, and when the resonance coil is seen in a direction of the coil center line, the coil wire that forms the resonance coil is formed so as not to be overlapped.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: March 14, 2017
    Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY
    Inventors: Shinji Ichikawa, Nobuyoshi Kikuma, Masafumi Kadoi
  • Patent number: 9548606
    Abstract: According to one embodiment, the A/D conversion unit includes a ?? modulating device which samples the analog electric quantity provided by the electric power system with a predetermined modulation frequency and outputs a bit stream changing over time of single bit obtained by performing ?? modulation, and the digital operation processing unit includes one or more digital filters which inputs the bit stream from the ?? modulating device and of which frequency characteristics differ according to a type of protection control operation, and one or more operation processing elements which perform different kinds of protection control operation processing, based on the bit stream provided by the digital filter.
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: January 17, 2017
    Assignees: KABUSHIKI KAISHA TOSHIBA, NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY
    Inventors: Daiju Itagaki, Shogo Miura, Katsuhiko Sekiguchi, Satoshi Hirano
  • Patent number: 9452553
    Abstract: Disclosed is a surface structure of an article (1) including multiple protrusions (3) on the surface. A height H of the protrusions (3) is equal to or larger than 5 ?m, and equal to or smaller than 32 ?m, as well as at least one of a distance P between each two neighboring protrusions (3) and a distance W between each neighboring two of recesses (5) formed between the protrusions (3) is larger than the height H of the protrusions (3).
    Type: Grant
    Filed: October 13, 2010
    Date of Patent: September 27, 2016
    Assignees: NISSAN MOTOR CO., LTD., NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY
    Inventors: Akane Motofuji, Makoto Tamuraya, Takashi Takeuchi, Hideo Fujimoto, Akihito Sano, Hiromi Mochiyama, Naoyuki Takesue, Yoshihiro Tanaka
  • Patent number: 9421877
    Abstract: A power transmission system has an AC power source and a high-frequency power driver that make up a high-frequency power source, and a primary self-resonant coil and a secondary self-resonant coil. The secondary self-resonant coil is magnetically coupled, by magnetic field resonance, to the primary self-resonant coil, and receives as a result high-frequency power from the primary self-resonant coil. The coils of the primary self-resonant coil and the secondary self-resonant coil resonate in an even mode when high-frequency power is transmitted from the primary self-resonant coil to the secondary self-resonant coil. Specifically, the primary self-resonant coil and the secondary self-resonant coil resonate in a state where currents in mutually opposite directions flow in the two coils.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: August 23, 2016
    Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY
    Inventors: Shinji Ichikawa, Tetsuhiro Ishikawa, Hiroshi Hirayama, Nobuyoshi Kikuma, Kunio Sakakibara