Patents Assigned to National University Corporation Nagoya University
  • Patent number: 10076745
    Abstract: A method and apparatus for producing core-shell type metal nanoparticles which are excellent in productivity are provided, in particular, the present invention provides a method of production of core-shell type metal nanoparticles including (a) a step of introducing a solution of a salt of a first metal to a first flow path of a flow type reaction apparatus and applying plasma to the solution of the salt of the first metal in the first flow path to obtain a solution which contains metal nanoparticles of the first metal and (b) a step of introducing a solution of a salt of a second metal to a second flow path of the flow type reaction apparatus, making it merge with the solution which contains metal nanoparticles of the first metal to obtain a mixed solution, and applying plasma to the mixed solution to cover the metal nanoparticles of the first metal by the second metal.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: September 18, 2018
    Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Masao Watanabe, Mamoru Ishikiriyama, Youhei Kinoshita, Nagahiro Saito, Tomohito Sudare
  • Publication number: 20180255072
    Abstract: A communication device capable of detecting transmission of an improper message to a network. A CAN controller in the gateway transmits and receives a message attached with a priority level (ID) to/from an ECU through a communication line, and counts, by the consecutive block number counter, the number of transmitted messages that are consecutively blocked as a result of arbitration processing as the number of consecutive blocks and stores the number as the number of allowed blocks into an allowed block number table in the storage unit in association with a priority level attached to the message received at the communication line. Every time a message is received, the controller compares the number of consecutive blocks with the number of allowed blocks for this message, and detects abnormality if the number of consecutive blocks is larger than the number of allowed blocks.
    Type: Application
    Filed: August 10, 2016
    Publication date: September 6, 2018
    Applicants: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, AUTONETWORKS TECHNOLOGIES, LTD., SUMITOMO WIRING SYSTEMS, LTD., SUMITOMO ELECTRIC INDUSTRIES, LTD.
    Inventors: Hiroaki TAKADA, Ryo KURACHI, Hiroshi UEDA, Satoshi HORIHATA
  • Patent number: 10066261
    Abstract: The present invention relates to a method for amplifying a nucleic acid. More specifically, the present invention relates to a method for amplifying a nucleic acid in a light irradiation dependent manner under a substantially isothermal condition using a photo-responsive nucleic acid.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: September 4, 2018
    Assignees: SYSMEX CORPORATION, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Seigo Suzuki, Hiroya Kirimura, Hiroyuki Asanuma
  • Publication number: 20180248143
    Abstract: A photoelectric conversion element includes: a pair of electrodes including a first electrode and a second electrode; a first insulator having a first capacitance, and disposed to make contact with the first electrode; a second insulator having a second capacitance, which is smaller than the first capacitance of the first insulator, and disposed to make contact with the second electrode; and an organic semiconductor receiving a light to generate an electromotive force, and interposed between the first insulator and the second insulator to make contact with them.
    Type: Application
    Filed: September 27, 2016
    Publication date: August 30, 2018
    Applicants: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, NISSHINBO HOLDINGS INC.
    Inventors: Kunio AWAGA, Simon DALGLEISH, Louisa REISSIG, Kanako YUYAMA
  • Publication number: 20180246129
    Abstract: Provided is a novel method and the like for diagnosing a lifestyle disease. The method for diagnosing a lifestyle disease provided by the present invention includes: collecting a biological sample from a subject; measuring the concentration of a fatty acid amide contained in the biological sample; determining whether the subject suffers from a lifestyle disease or a lifestyle disease has progressed when the measured value of the concentration of the fatty acid amide in the sample obtained from the subject is lower than a measurement result obtained from a healthy subject.
    Type: Application
    Filed: February 27, 2018
    Publication date: August 30, 2018
    Applicants: TOYOTA JIDOSHA KABUSHIKI KAISHA, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Koji UCHIDA, Takahiro SHIBATA, Kenji ISHIKAWA, Oi Lun Helena LI, Tadashi MATSUSHITA, Ryosuke KIKUCHI, Junzo UKAI
  • Patent number: 10052298
    Abstract: The invention provides a method of increasing blood flow in a subject in need of increased blood flow by administering citrulline or a salt thereof and arginine or a salt thereof to the subject.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: August 21, 2018
    Assignees: Kyowa Hakko Bio Co., Ltd., National University Corporation Nagoya University
    Inventors: Masayuki Ochiai, Koji Morishita, Toshio Hayashi
  • Patent number: 10053459
    Abstract: The present invention provides a life-extending agent comprising pyrroloquinoline quinone and/or a derivative of the pyrroloquinoline quinone.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: August 21, 2018
    Assignees: National University Corporation Nagoya University, Mitsubishi Gas Chemical Company, Inc.
    Inventors: Ikue Mori, Hiroyuki Sasakura, Kazuto Ikemoto, Masahiko Nakano
  • Patent number: 10049232
    Abstract: A rewrite detection system, a rewrite detection device and an information processing device can detect unauthorized rewrite to a program or data stored in a storage unit of the information processing device. A rewrite detection device generates a random seed and transmits it to an ECU and a server device. The ECU calculates a hash value using a predetermined hash function on the basis of the received random seed and the storage content of the storage unit, and transmits the hash value to the rewrite detection device. The server device transmits an expectation in response to an inquiry from the rewrite detection device. The rewrite detection device determines whether unauthorized rewrite to a program or data in the ECU has been performed or not in accordance with whether the expectation received from the server device and the hash value received from the ECU coincide with each other or not.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: August 14, 2018
    Assignees: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, AUTONETWORKS TECHNOLOGIES LTD., SUMITOMO WIRING SYSTEMS, LTD., SUMITOMO ELECTRIC INDUSTRIES, LTD.
    Inventors: Hiroaki Takada, Hiroki Takakura, Yukihiro Miyashita, Satoshi Horihata, Hiroshi Okada, Naoki Adachi
  • Publication number: 20180224383
    Abstract: An orientation evaluation device includes: a diode laser configured to periodically irradiate a sample with light to heat the sample, the sample being carbon fiber reinforced plastics; an infrared thermography configured to detect delay in response to a change in a temperature distribution of an area of the sample, the area including a spot heated by the diode laser; and a computer configured to output information on orientation of the sample based on the delay in the response detected by the infrared thermography. The orientation evaluation device enables a non-contact and quick evaluation of the orientation of the sample.
    Type: Application
    Filed: June 10, 2016
    Publication date: August 9, 2018
    Applicant: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Hosei NAGANO, Ryouhei FUJITA
  • Patent number: 10034889
    Abstract: The purpose of the present invention is to identify a migratory factor that guides pluripotent stem cells (Muse cells) useful in new medical applications to damage, and to provide a pharmaceutical composition that includes the migratory factor for promoting tissue regeneration in regenerative medicine that makes use of Muse cells. In the present invention, a receptor that is specifically expressed in Muse cells rather than non-Muse cells was identified, and it was confirmed that a ligand for this receptor can function as a migratory factor. In the present invention, sphingosine-1-phosphate (S1P) was identified as a migratory factor, and thus, the present invention pertains to a pharmaceutical composition for guiding pluripotent stem cells to damage, the composition including S1P as an active ingredient.
    Type: Grant
    Filed: August 16, 2016
    Date of Patent: July 31, 2018
    Assignees: CLIO, INC., TOHOKU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Mari Dezawa, Yoshinori Fujiyoshi, Masanori Yoshida
  • Patent number: 10012586
    Abstract: A method and apparatus for analyzing carbon isotope 14C is provided. A carbon isotope analyzer including an isotopic carbon dioxide generator to generate isotopic carbon dioxide from a carbon isotope; a spectrometer including an optical resonator having a pair of mirrors, and a photodetector to determine the intensity of light transmitted from the optical resonator; and a light generator including a light source, a first optical fiber to transmit a light beam from the light source, a second optical fiber for wavelength conversion, the second optical fiber branching from the first optical fiber at a point and combining with the first optical fiber at another point downstream of the branching point, and a non-linear optical crystal to generate light having the absorption wavelength of the isotopic carbon dioxide on the basis of the difference in frequency between light beams transmitted through the optical crystal.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: July 3, 2018
    Assignees: SEKISUI MEDICAL CO., LTD., NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Tetsuo Iguchi, Hideki Tomita, Norihiko Nishizawa, Toshinari Oh-Hara, Akira Ideno
  • Patent number: 10012705
    Abstract: Magnetic-field measuring device having: elongate magnetic-material formed of solid or liquid having magnetic-anisotropy, or composite of solid and liquid; an electrically conductive-body adjacent to magnetic-material, giving magnetic-material a current-induced magnetic-field-vector having a component perpendicular to longitudinal-directions of magnetic-material; coil detecting magnetic-field by magnetic-material, which is magnetized in a direction perpendicular to its longitudinal-direction when no external magnetic-field is applied to magnetic-material or when only a magnetic-field not having a component in longitudinal-direction applied to magnetic-material, and magnetizing in direction having the component in longitudinal-direction when external magnetic-field have the component in longitudinal-direction of magnetic-material applied to magnetic-material, a direction of magnetization of magnetic-material aligned with direction perpendicular to longitudinal-direction of magnetic-material when magnetic-materi
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: July 3, 2018
    Assignees: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, FUJIDENOLO CO., LTD.
    Inventors: Shinsuke Nakayama, Hideki Miyazaki
  • Patent number: 10007029
    Abstract: [1] A ?-phellandrene polymer which is a polymerization product of ?-phellandrene. [2] The ?-phellandrene polymer comprising ?-phellandrene units represented by chemical formulae (I-1), (I-2), (II-1) and (II-2), a total amount of the ?-phellandrene units being 50% by mass or more. [3] The ?-phellandrene polymer, which has a number average molecular weight Mn of 40,000 or more. [4] The ?-phellandrene polymer, wherein at least a part of olefinic carbon-carbon double bonds thereof are hydrogenated. [5] The ?-phellandrene polymer, which has a glass transition temperature of 80° C. or more.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: June 26, 2018
    Assignees: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, SEKISUI CHEMICAL CO., LTD.
    Inventors: Masami Kamigaito, Kotaro Satoh, Shinya Suzuki, Yasuyuki Kori, Yuji Eguchi, Koichiro Iwasa, Hitoshi Shirato
  • Patent number: 9972476
    Abstract: A film forming device includes: a microwave supplying unit configured to supply microwaves for generating plasma along a treatment surface of a conductive workpiece; a negative voltage applying unit configured to apply to the workpiece a negative bias voltage for expanding a sheath layer thickness along the treatment surface of the workpiece, and a controller configured to control the microwave supplying unit and the negative voltage applying unit, wherein the microwave supplying unit has a microwave transmitting window configured to propagate the supplied microwaves to the expanded sheath layer, wherein the controller is configured to control the microwave supplying unit and the negative voltage applying unit while supplying of the microwaves so that a sheath thickness of the sheath layer changes.
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: May 15, 2018
    Assignees: BROTHER KOGYO KABUSHIKI KAISHA, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Kazunari Taki, Kentaro Shinoda, Hideki Kanada, Hiroyuki Kousaka, Yasuyuki Takaoka
  • Patent number: 9968932
    Abstract: Provided is a microchannel chip, for microparticle separation, which can continuously separate microparticles, from a solution in which microparticles of different particle diameter are mixed, without needing to use an antibody or similar, and without causing clogging. Also provided are a microparticle separation method and a system for microparticle separation using the chip. Microparticles can be captured by using the microchannel chip for microparticle separation, the microchannel chip being characterised by being provided with a plurality of main channels and capture portions that are wider than the main channels and at least one of which is provided to each main channel.
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: May 15, 2018
    Assignee: National University Corporation Nagoya University
    Inventors: Fumihito Arai, Taisuke Masuda, Miyako Niimi, Haruki Douke, Hayao Nakanishi, Seiji Ito
  • Patent number: 9962428
    Abstract: A composition having tissue repair activity, which is capable of promoting reactions associated with tissue repair, contains at least one selected from the group consisting of a first component that is a protein having a monocyte chemotactic protein-1 (MCP-1) activity, a second component that is a protein having the extracellular domain activity of sialic acid-binding immunoglobulin-type lectin-9 (Siglec-9), and a third component that is at least one of chondroitin sulfate and chondroitin sulfate proteoglycan.
    Type: Grant
    Filed: December 24, 2013
    Date of Patent: May 8, 2018
    Assignee: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Akihito Yamamoto, Minoru Ueda, Kohki Matsubara, Akio Suzumura, Koichi Furukawa, Yoshihiro Matsushita, Hirotaka Wakayama, Nobunori Takahashi, Shin Tsunekawa, Takako Izumoto
  • Publication number: 20180114670
    Abstract: An electromagnetic lens for charged particle beam exhibits positive spherical aberration. A complicated combination of electromagnetic lenses had been necessary for correcting this spherical aberration. One of a circular aperture or a ring-shaped aperture is provided on an incident plate arranged on an incident side of charged particle beam, another of the circular aperture or the ring-shaped aperture is provided on a plate arranged on an emission side thereof, and a voltage is applied between the incident plate and the emission plate. By so doing, an electric field generated in the ring-shaped aperture emanates, which resolves the positive spherical aberration. The spherical aberration can be corrected by an extremely simple and easily implemented structure.
    Type: Application
    Filed: February 8, 2016
    Publication date: April 26, 2018
    Applicant: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Tadahiro KAWASAKI, Takayoshi TANJI, Takashi IKUTA
  • Patent number: 9951094
    Abstract: The following formula is an example of a phosphole compound of the present invention. The phosphole compound of the present invention has the characteristic of maintaining a high fluorescence quantum yield in a wide range of solvents from low-polarity solvents to high-polarity solvents, as well as the characteristic in which the fluorescence wavelength shifts to the longer wavelength side as the polarity of the solvent increases. Because of these characteristics, the phosphole compound of the present invention is expected to be used, for example, for quantitatively determining the polarity in the environment therearound by using the absorption wavelength and fluorescence wavelength thereof, or used as a new fluorescent probe dye or a highly efficient luminescent material in organic electronic devices.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: April 24, 2018
    Assignee: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Shigehiro Yamaguchi, Aiko Fukazawa, Eriko Yamaguchi, Chenguang Wang
  • Patent number: 9934926
    Abstract: The present disclosure provides a treatment device for lowering electron affinity. The treatment device is capable of performing an electron affinity (EA) surface treatment on a photocathode material or an EA surface retreatment on a photocathode. The present disclosure also provides an electron-beam device provided with the treatment device. An activation chamber is used in a treatment device for lowering electron affinity by vaporizing a surface-treatment material and uses the vaporized surface-treatment material to perform an electron-affinity lowering treatment on a photocathode material or an electron-affinity lowering retreatment on a photocathode. The activation chamber includes one or more holes through which electrons can pass.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: April 3, 2018
    Assignee: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventor: Tomohiro Nishitani
  • Publication number: 20180087151
    Abstract: In an amorphous carbon film of a sliding member, provided that a number of nitrogen atoms each singly bonded to three carbon atoms is A, and a number of nitrogen atoms each singly and doubly bonded to two carbon atoms, respectively, is B, a value A/B of the amorphous carbon film obtained through X-ray photoelectron spectroscopy analysis is 10 to 18. The method includes irradiating the surface of the substrate with nitrogen ion beams and irradiating a carbon target with electron beams, thereby forming an amorphous carbon film on the surface of the substrate while vapor-depositing a part of the carbon target onto the surface of the substrate. The output of the electron beams that irradiate the carbon target is 30 to 50 W.
    Type: Application
    Filed: September 26, 2017
    Publication date: March 29, 2018
    Applicants: TOYOTA JIDOSHA KABUSHIKI KAISHA, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Kazuyoshi MANABE, Noritsugu UMEHARA, Hiroyuki KOUSAKA, Kazuyuki ICHIMURA