Abstract: The present invention provides a peptide that consists of an amino acid sequence with 20 or fewer residues containing at least one amino acid sequence selected from the group consisting of the amino acid sequence represented in SEQ ID NO: 1, the amino acid sequence represented in SEQ ID NO: 2 and the amino acid sequence represented in SEQ ID NO: 38, the peptide having an activity to inhibit proliferation of a tumor cell or having an activity to inhibit binding between an epidermal growth factor receptor and a signal-transducing adaptor family member-2 (STAP-2); a peptide with a cell-penetrating peptide added to a terminus of the above peptide with or without a linker sequence interposed between the cell-penetrating peptide and the terminus; and pharmaceutical compositions containing any of these peptides.

Abstract: An inactivated whole-virus influenza vaccine may have its antibody-inducing ability is maintained or enhanced and may cause fewer side reactions. A method for preparing an inactivated whole-virus influenza vaccine may use an embryonated chicken egg method, including subjecting a virus solution including a whole influenza virus collected from embryonated chicken eggs to a hypotonic treatment.

Abstract: A device produces fine bubbles that has a simple configuration and that is capable of generating fine bubbles. This fine bubble generation device includes: a porous body having continuous pores; a liquid supply section that supplies a liquid to the porous body and causes the liquid to circulate through the continuous pores; and a liquid discharge section for discharging liquid that has circulated through the continuous pores.

Abstract: The polycarbonate resin composition according to the present invention includes: 50 to 90% by mass of polycarbonate resin (A); 2.0 to 20% by mass of olefin polymer (B); 5 to 40% by mass of basic magnesium sulfate (C) selected from fibrous basic magnesium sulfate (C-1) and fan-shaped basic magnesium sulfate (C-2); 0.1 to 8% by mass of at least one (D) selected from a fatty acid metal salt and a fatty acid; and 1 to 20% by mass of elastomer (E).

Abstract: This method for producing a fiber-reinforced composite material includes: a fiber dispersion process of providing a fiber-dispersed resin by kneading a resin 10a with fibers 10b to disperse the fibers 10b in the resin 10a; and a molecular weight reduction process in which, while transporting the fiber-dispersed resin along an outer peripheral surface of a screw body 37 provided with a passage 88 inside, the fiber-dispersed resin passes from an inlet 91 of the passage 88 to an outlet 92 of the passage 88 and a shear force is applied to the fiber-dispersed resin by restricting the transport of the fiber-dispersed resin with a barrier unit 82 disposed between the inlet 91 and the outlet 92 of the passage 88 on the outer peripheral surface.

Abstract: A coating agent including a polyrotaxane represented by Formula (1): wherein R1 is a hydrogen atom or a methyl group, m is 1 to 2000, and n is 10 to 500, is a cyclodextrin in which at least one hydroxyl group is modified with R2, and R2 is a C1-6 alkyl group.

Abstract: A controller uses detection information of a contact sensor or time-series data of a detection value related to a drive motor included in a rotation mechanism and/or a feed mechanism to acquire a coordinate value when a cutting tool comes into contact with a to-be-cut object or a component. The controller determines a relative positional relationship between the cutting tool and a rotation center of the to-be-cut object based on coordinate values when the cutting tool comes into contact with the to-be-cut object subjected to turning work or a reference surface whose relative positional relationship with the rotation center of the to-be-cut object is known at least at two positions different from a rotation angle position of the cutting tool during the turning work.

Abstract: A particle therapy system includes an accelerator 1 which generates a particle beam for extraction, an irradiation apparatus 21 which irradiates the particle beam to an irradiation target 26, a gantry 18 which rotates together with the irradiation apparatus 21, and an MRI apparatus 50 which rotates together with the gantry 18. The MRI apparatus 50 includes a magnetic circuit composed of an iron core 60 and a plurality of coils 61 serving as a magnetic flux source. The iron core 60 includes two oppositely disposed magnetic poles 63A and 63B, and a return yoke 64 for connecting the magnetic poles 63A and 63B. The magnetic poles 63A, 63B have cavities 65A, 65B. The particle beam passing through the cavity 65A is irradiated to the irradiation target 26.

Abstract: This invention relates to a preventive and/or therapeutic agent for sarcopenia, comprising a prostaglandin D2 production inhibitor as an active ingredient.

Abstract: It is desired to develop a method of producing hydrogen peroxide, which is capable of producing hydrogen peroxide with high production efficiency. According to the present invention, provided is a palladium-containing composition comprising palladium particles and a coating agent that coats the surface of the palladium particles, wherein a compound having an O?X structure (wherein X represents any of a phosphorus atom, a sulfur atom, and a carbon atom) is comprised as the coating agent.

Abstract: [Object] An object is to provide a sulfonated fine cellulose fiber having excellent transparency, a sulfonated pulp fiber suitable for the sulfonated fine cellulose fiber, a method for producing these fibers, and a derivative pulp containing the sulfonated pulp fiber. [Means for achieving the object] The sulfonated pulp fiber of the present invention is a pulp fiber comprising a plurality of cellulose fibers, wherein a part of hydroxyl groups of the cellulose fibers of the pulp fiber is substituted with sulfo groups, an introduction amount of sulfur attributable to the sulfo groups is adjusted to be higher than 0.42 mmol/g while maintaining a fiber shape, and a water retention value of the pulp fiber is adjusted to 150% or more. Since the sulfonated pulp fiber has a predetermined water retaining property or more while maintaining the fiber shape, the degree of flexibility in handling can be improved.

Abstract: It is an object to provide a technique useful for embryo transfer and development of reproductive medical care. Provided are a sperm activator containing a disrupted product of one or more cells selected from the group consisting of adipose tissue-derived stem cells, dental pulp-derived stem cells, bone marrow-derived stem cells, and umbilical cord blood-derived stem cells as an active ingredient, and an artificial insemination method utilizing the same.

Abstract: The present invention relates to a method of producing cancer stem cells that comprises culturing a living cell population containing cancer cells in the presence of a gel substance to obtain a living cell population containing cancer stem cells, wherein the gel substance is a material that induces expression of osteopontin in at least a portion of cells contained in the living cell population. Moreover, the present invention relates to an agent for inducing conversion of cancer cells to cancer stem cells that comprises a gel substance that induces expression of osteopontin in at least a portion of the cells contained in a living cell population. The gel substance is a synthetic polymer gel composed of, for example, double network gel, PNaSS gel, PCDME gel, PA gel, PAMPS gel, PDMA gel or PAAc gel. The present invention provides means and a method that enable the preparation of cancer stem cells in a relatively short period of time and at a relatively low culturing cost without requiring expensive equipment.

Abstract: A diagnostic support apparatus includes a computing unit that computes a decreasing rate of a current intensity of an inward current flowing into a nerve pathway, based on magnetic field data obtained by measuring a magnetic field generated by a subject.

Abstract: The objective of the present invention is to provide a novel bacteriophage useful for treating bacterial endophthalmitis and a therapeutic agent for bacterial endophthalmitis comprising the novel bacteriophage. The therapeutic agent for bacterial endophthalmitis according to the present invention is characterized in comprising 1 or more bacteriophages selected from the group essentially consisting of Myoviridae Spounavirinae phiEF7H (accession number: NITE BP-02886), Myoviridae Spounavirinae phiEF19G (accession number: NITE BP-02887), Myoviridae Spounavirinae phiEF14H1 (accession number: NITE BP-02888), and mutants thereof.

Abstract: The present invention provides a coronary artery bypass surgery treatment tool or the like including a flexible tube, a suction cup in which an opening portion is formed to communicate with the flexible tube and which is provided at a distal end of the flexible tube, a joint portion which has a suction path, a male connector which is provided in one of a proximal end of the flexible tube and a distal end of the suction path of the joint portion, and a female connector which is provided in the other thereof and is detachably connected to the male connector.

Abstract: An object of the present invention is to provide a novel chimeric antigen receptor. The object can be achieved by a chimeric antigen receptor, comprising an antigen-binding domain, a transmembrane domain, and an intracellular signal domain containing a CD79A intracellular domain and a CD40 intracellular domain, wherein (A) the number of constituent amino acid residues between the antigen-binding domain and the transmembrane domain is 100 or less and/or (B) a target antigen of the antigen-binding domain is an antigen other than CD19.

Abstract: The present invention relates to a thermal insulator containing a polymer sorbent that regenerates by desorbing adsorbed moisture, and a thermal insulation material. The thermal insulator of the present invention has the thermal insulation performance and prevents deterioration of the object by repeatedly absorbing liquid water between the object to be thermally insulated and the thermal insulator to reduce and prevent retention of water droplets between an object to be thermally insulated and a thermal insulator.

Abstract: The endplate perforator includes a pipe, an operation portion disposed at a rear end of the pipe, a case that is disposed at a front end of the pipe and includes an insertion surface configured to be placed parallel to an endplate of a vertebra, a needle member housed in the case and configured to perforate the endplate of the vertebra, and a mechanism portion configured move the needle member in a direction perpendicular to the insertion surface in response to an operation of the operation portion to cause the needle member to project or retract relative to the case.

Abstract: The present invention relates to an improved technology for a device that identifies and diagnoses an environmental stress state of plants. An environmental stress diagnosis device comprises a measurement light source 12, an induction light source 14, and a transmitted light detector 18. The measurement light source 12 radiates a first measurement light ML1 and a second measurement light ML2 to a plant sample S, the induction light source 14 radiates a first photosynthesis inducing light FR and a second photosynthesis inducing light AL to the plant sample S, and the transmitted light detector 18 detects a first transmitted light TL1 and a second transmitted light TL2. The control unit 20 has an analysis circuit 20a and a control circuit 20b.