Patents Assigned to National University of Singapore
  • Publication number: 20250045482
    Abstract: Disclosed is a method for managing digital twins of a plurality of physical assets. The system comprises a digital platform, database and a plurality of processors. The processors import real world data from the physical assets to the database, process the real world data to generate calibration data, map a plurality of digital twins to the digital platform, each digital twin for simulating a corresponding physical asset, predict simulation data by the digital twins, compare the simulation data with the calibration data to assess performance of the digital twins, determine a set of low-performance digital twins based on the performance of the digital twins, and apply an optimization model to update the digital twins.
    Type: Application
    Filed: November 11, 2022
    Publication date: February 6, 2025
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Sushant Suhas GARUD, Iftekhar Abubakar KARIMI
  • Patent number: 12218201
    Abstract: A semiconductor structure, including: a base substrate; an insulating layer on the base substrate, the insulating layer having a thickness between about 5 nm and about 100 nm; and an active layer comprising at least two pluralities of different volumes of semiconductor material comprising silicon, germanium, and/or silicon germanium, the active layer disposed over the insulating layer, the at least two pluralities of different volumes of semiconductor material comprising: a first plurality of volumes of semiconductor material having a tensile strain of at least about 0.6%; and a second plurality of volumes of semiconductor material having a compressive strain of at least about ?0.6%. Also described is a method of preparing a semiconductor structure and a segmented strained silicon-on-insulator device.
    Type: Grant
    Filed: June 14, 2021
    Date of Patent: February 4, 2025
    Assignees: National University of Singapore, Soitec
    Inventors: Bich-Yen Nguyen, Christophe Maleville, Walter Schwarzenbach, Gong Xiao, Aaron Thean, Chen Sun, Haiwen Xu
  • Patent number: 12217094
    Abstract: The present disclosure provides a method and an apparatus of resource adjustment for a service cluster, an electronic device and a storage medium. The method includes: determining resource adjustment information for the service cluster according to a task quantity of streaming data processing tasks to be processed; determining a core quantity to be adjusted corresponding to central processor units and the second quantity of computing nodes to be adjusted, according to the parallelism degree to be adjusted, the first quantity of the computing nodes that have been created in the service cluster, and a resource utilization rate of central processor units in each computing node that has been created; and executing the resource adjustment operation according to the core quantity to be adjusted and the second quantity, and obtaining a service cluster subject to resource adjusting.
    Type: Grant
    Filed: June 20, 2024
    Date of Patent: February 4, 2025
    Assignees: Beijing Volcano Engine Technology Co., Ltd., National University of Singapore
    Inventors: Yifan Zhang, Zhanghao Chen, Meng Wang, Guanghui Zhang, Yong Fang, Rui Shi, Tianbai Ma, Yancan Mao
  • Publication number: 20250040258
    Abstract: Disclosed is a tandem solar module and a method for forming such a module. The module includes a plurality of cell strips formed by cutting a full cell parallel to a direction of extension of a bus bar of the full cell, a plurality of strings arranged in one or more parallel sets, each string comprising two or more said cells strips interconnected end-to-end with respect to the direction of extension, and a terminal at each opposite end the one or more parallel sets.
    Type: Application
    Filed: December 5, 2022
    Publication date: January 30, 2025
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Jai PRAKASH, Shubham DUTTAGUPTA, Nitin NAMPALLI, Carlos Enrico Cobar
  • Patent number: 12212367
    Abstract: A method of encoding quantum information on one or several degrees of freedom of coherent states of photons of a baseband input optical signal, a quantum transmitter, and a computer-readable medium. The quantum transmitter comprises a modulator configured to encode quantum information on one or several degrees of freedom of coherent states of photons of a baseband input optical signal using sideband modulation of the baseband optical input signal.
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: January 28, 2025
    Assignee: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Chao Wang, Ci Wen Lim, Koon Tong Goh
  • Publication number: 20250029383
    Abstract: A relationship extracting apparatus acquires event information that indicates features of an event of interest, determine target duration based on one or more features of the event of interest, and extract one or more action-related relationships that exist during the target duration from object relationships information. The object relationship information indicates two or more action-related relationships between objects in association with time at which or during which the action-related relationship exists.
    Type: Application
    Filed: July 19, 2024
    Publication date: January 23, 2025
    Applicants: NEC CORPORATION, National University of Singapore
    Inventors: Karen STEPHEN, Satoshi Yamazaki, Jianquan LIU, Rishabh Sheoran, Yong Kang Wong, Mohan Kankanhalli
  • Patent number: 12204184
    Abstract: A structure for an optoelectronics platform and a method of fabricating a structure for an optoelectronics platform such as a Mach-Zehnder modulator or a waveguide. The method comprises the steps of providing a substrate, and depositing a BaTi03, BTO, film on a surface of the substrate and having a thickness suitable for single mode operation with one or more possible polarization configurations with optical confinement in the BTO film at a wavelength or wavelength range of operation; wherein the substrate is chosen to provide vertical refractive index confinement in a direction perpendicular to the surface of the substrate for the single mode operation optical confinement in the BTO film at the wavelength or wavelength range of operation.
    Type: Grant
    Filed: March 26, 2020
    Date of Patent: January 21, 2025
    Assignee: National University of Singapore
    Inventors: Yu Cao, Shawn Yohanes Siew, Aaron James Danner, Thirumalai Venky Venkatesan
  • Patent number: 12202202
    Abstract: A personalized naturally designed mitral valve prosthesis and a method for manufacturing the such to precisely fit a specific patient for which the valve prosthesis is made for, is provided. The method includes measuring size and shape of a mitral valve of the specific patient by using imaging means, building a 3D model of the personalized mitral valve prosthesis, optimizing the 3D model using FEM method and fabricating the personalized mitral valve prosthesis by cutting and connecting the annular ring, leaflets and chords to form a personalized prosthesis mitral valve.
    Type: Grant
    Filed: April 15, 2021
    Date of Patent: January 21, 2025
    Assignees: NATIONAL UNIVERSITY OF SINGAPORE, NATIONAL UNIVERSITY HOSPITAL (SINGAPORE) PTE LTD
    Inventor: Theodoros Kofidis
  • Publication number: 20250020589
    Abstract: A metasurface uses pairs of nanorod plasmonic resonators that are arranged perpendicular to each other and have an in-plane asymmetry and an out-of-plane asymmetry in their geometric arrangement. The metasurface can be used to provide chirality sensor that provides an enhanced vibrational circular dichroism signal. The sensor can be used in various different molecule-sensing applications.
    Type: Application
    Filed: July 10, 2024
    Publication date: January 16, 2025
    Applicant: National University of Singapore
    Inventors: Cheng XU, Zhihao REN, Chengkuo LEE
  • Patent number: 12195526
    Abstract: The invention relates to methods for producing an antibody which is specific for a mutant p53 polypeptide over wildtype p53 polypeptide, comprising using as an immunogen a peptide or polypeptide comprising: (i) an antigen sequence, comprising an amino acid sequence of the mutant p53 polypeptide including the mutation and at least one amino acid immediately adjacent to the mutation, and (ii) a scaffold sequence for providing the antigen sequence in a solvent-accessible configuration. Also provided are antibodies produced by such methods, and uses thereof.
    Type: Grant
    Filed: February 22, 2023
    Date of Patent: January 14, 2025
    Assignees: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, Singapore Health Services Pte Ltd, NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Tr Kanaga Sabapathy, David P. Lane, Le-Ann Hwang, Xin Yu Koh, Liew Oi Wah
  • Patent number: 12187869
    Abstract: A polyethylene terephthalate aerogel. There is provided a polyethylene terephthalate (PET) aerogel comprising a porous network of cross-linked recycled PET fibers, wherein the PET aerogel has a thermal conductivity of 0.030-0.050 W/m K. There is also provided a method of forming the PET aerogel.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: January 7, 2025
    Assignees: Agency for Science, Technology and Research, National University of Singapore
    Inventors: Hai Minh Duong, Nhan Phan Thien, Thanh Xuan Nguyen, Salomo Steven, Xiwen Zhang, Duyen Khac Le
  • Patent number: 12171731
    Abstract: The present disclosure is directed to methods of treating a steatosis- associated disorder by administering a therapeutic agent selected from a lysosomal enzyme, an autophagy-inducing agent, or a combination thereof. Steatosis-associated disorders discussed herein include GSD Ia, GSD Ib, GSD Ic, NAFLD, and NASH. Other embodiments are directed to methods of reversing steatosis, modulating autophagy, inducing autophagy, and reversing glycogen storage.
    Type: Grant
    Filed: May 22, 2023
    Date of Patent: December 24, 2024
    Assignees: Duke University, National University of Singapore
    Inventors: Dwight D. Koeberl, Paul M. Yen, Benjamin L. Farah
  • Patent number: 12161979
    Abstract: The present invention provides a composite membrane suitable for liquid-liquid filtration/reverse osmosis. The invention also provides a copolymer useful in the composite membrane, the copolymer comprising an anchoring repeating unit and a foulant-repelling repeating unit, as well as methods for preparing the composite membrane and copolymers. In a preferred embodiment, a copolymer (P [SBMA-co-HEMA]) is synthesized via the free radical copolymerization of a zwitterionic monomer of sulfobetaine methacrylate (SBMA) and an anchoring monomer of hydroxyl ethyl methacrylate (HEMA).
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: December 10, 2024
    Assignee: National University of Singapore
    Inventors: Yu Zhang, Tai-Shung Chung, Sui Zhang, Feng Li
  • Publication number: 20240398896
    Abstract: The present disclosure provides ASC inhibitors, compositions comprising said ASC inhibitors, methods of identifying said ASC inhibitors, and therapeutic and prophylactic methods of using said ASC inhibitors.
    Type: Application
    Filed: September 27, 2022
    Publication date: December 5, 2024
    Applicant: National University of Singapore
    Inventors: Lin-Fa Wang, Matae Ahn, Vivian Chih-Wei Chen
  • Publication number: 20240400823
    Abstract: The invention relates to a polymeric composite comprising poly(ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), waterborne polyurethane (WPU) and a sugar alcohol, wherein the sugar alcohol is selected from the group consisting of glycerol, erythritol, threitol, arabitol, xylitol, ribitol, mannitol, sorbitol, galactitol, fucitol, iditol, inositol, volemitol, isomalt, maltitol, lactitol, maltotriitol, maltotetraitol, polyglycitol, or a combination thereof, and wherein the sugar alcohol is 20 wt % to 50 wt % of the polymer composite; an electrical device comprising such composite. The present invention also relates to methods of fabricating and its uses thereof. In particular, the present invention relates to intrinsically conductive polymer composites suitable for use in efficient dry/wet epidermal biopotential monitoring. The polymer composites are advantageously self-adhesive and stretchable, and can be used as dry electrodes.
    Type: Application
    Filed: October 16, 2020
    Publication date: December 5, 2024
    Applicant: National University of Singapore
    Inventors: Jianyong OUYANG, Lei ZHANG, Hongliang REN, Kirthika SENTHIL KUMAR
  • Patent number: 12157713
    Abstract: Disclosed herein are compounds of formula I, where said compounds displays antibacterial properties. Also disclosed herein is the use of said compounds to treat microbial infection. The compounds of formula I have the following structure: where n, m, p, q, X, R1 to R11 are as defined herein.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: December 3, 2024
    Assignees: Nanyang Technological University, National University of Singapore
    Inventors: Jamie Hinks, Cheng Zhou, Guillermo C. Bazan
  • Publication number: 20240377701
    Abstract: An optical tweezer arrays system and a method of arranging a particle array. In one embodiment, the optical tweezer arrays system comprises first and second optical paths from respective light sources to a substrate; and a sensor for imaging the particle array; wherein the first optical path comprises a first pair of acousto-optic deflectors configured for deflecting a first light beam for generating static optical tweezers for the particle array on the substrate; and wherein the second optical path comprises a second pair of acousto-optic deflectors configured for deflecting a second light beam for generating multiple mobile optical tweezers simultaneously for re-arranging particles in the particle array on the substrate.
    Type: Application
    Filed: May 12, 2023
    Publication date: November 14, 2024
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Weikun TIAN, Wen Jun WEE, An QU, Jun Ming LIM, Prithvi Raj DATLA, Vanessa Pei Wen KOH, Huanqian LOH
  • Publication number: 20240377252
    Abstract: Infrared spectrometer and method of performing infrared spectrometry.
    Type: Application
    Filed: July 22, 2022
    Publication date: November 14, 2024
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Zi Heng LIM, Yi QI, Senthil Kumar ANANTHARAJAN, Chengkuo LEE, Guangya ZHOU
  • Patent number: 12143705
    Abstract: An assembly and method of switching direction of camera view. The method comprises disposing a beam splitter element on a camera, the beam splitter element being configured such that first and second beams of light incident on first and second faces, respectively, of the beam splitter element are directable towards an entry lens of the camera; disposing first and second shutter elements in the paths of the first and second beams of light, respectively; and controlling the first and second shutter elements such that one of the first and second shutter elements is in an open state while the other one is in a closed state, and vice-versa.
    Type: Grant
    Filed: May 15, 2023
    Date of Patent: November 12, 2024
    Assignee: National University of Singapore
    Inventor: Mark Breese
  • Patent number: 12138742
    Abstract: Methods and apparatus for processing a substrate are provided herein. For example, a method of processing a substrate using extended spectroscopic ellipsometry (ESE) includes directing a beam from an extended spectroscopic ellipsometer toward a surface of a substrate for determining in-situ ESE data therefrom during substrate processing, measuring a change of phase and amplitude in determined in-situ ESE data, and determining various aspects of the surface of the substrate using simultaneously complex dielectric function, optical conductivity, and electronic correlations from a measured change of phase and amplitude in the in-situ ESE data.
    Type: Grant
    Filed: February 16, 2021
    Date of Patent: November 12, 2024
    Assignees: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Prayudi Lianto, Guan Huei See, Arvind Sundarrajan, Andrivo Rusydi, Muhammad Avicenna Naradipa