Patents Assigned to NAZIONALE DELLE RICERCHE
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Patent number: 9575029Abstract: A transistor includes at least one conductive layer, at least one gate dielectric layer and at least one semiconducting film deposited on top of a receptor molecule layer previously deposited or covalently linked to the surface of the gate dielectric. The layer of biological material includes single or double layers of phospholipids, layers made of proteins such as receptors, antibodies, ionic channels and enzymes, single or double layers of phospholipids with inclusion or anchoring of proteins such as: receptors, antibodies, ionic channels and enzymes, layers made of oligonucleotide (DNA, RNA, PNA) probes, layers made of cells or viruses, layers made of synthetic receptors for example molecules or macromolecules similar to biological receptors for properties, reactivity or steric aspects.Type: GrantFiled: October 31, 2011Date of Patent: February 21, 2017Assignees: UNIVERSITA DEGLI STUDI DI BARI, CONSIGLIO NAZIONALE DELLE RICERCHE ISTITUTO PROCESSI CHIMICO FISICI-IPCF, SEDE DI BARIInventors: Luisa Torsi, Gerardo Palazzo, Nicola Cioffi, Maria Daniela Angione, Maria Magliulo, Serafina Cotrone, Gaetano Scamarcio, Luigia Sabbatini, Antonia Mallardi
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Patent number: 9561355Abstract: There is described a method for making an array of micro-needles, comprising the steps of: depositing a plurality of drops of a liquid substance comprising a polymer on a surface of a starting substrate; positioning a pyroelectric substrate at a certain distance from the starting substrate in such a way that the drops deposited are positioned between said surface of the starting substrate and a surface of the pyroelectric substrate; varying the temperature of the pyroelectric substrate or a part thereof to induce on said surface of the pyroelectric substrate a charge density such that starting from the drops deposited, under the effect of an electrodynamic force, respective cones are formed having a tip facing towards the pyroelectric substrate; determining a consolidation of the cones, to form said micro-needles, preventing the tip of said cones from contacting said surfaces of the pyroelectric substrate.Type: GrantFiled: February 11, 2014Date of Patent: February 7, 2017Assignees: CONSIGLIO NAZIONALE DELLE RICERCHE, FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIAInventors: Pietro Ferraro, Sara Coppola, Andrea Finizio, Simonetta Grilli, Veronica Vespini, Paolo Antonio Netti, Raffaele Vecchione, Eliana Esposito
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Patent number: 9505086Abstract: In a method for detecting flaws in continuous laser welding processes, including a sensor measures plasma emission spectrum in a range of wavelengths between ?max and ?min in N channels, each measuring radiation strength emitted in the band centered at wavelength ?i (1?i?N) and width ??i. Deviation detection is based upon calculating intensity relationships of signals measured at specific wavelengths and in comparison with pre-determined threshold values. A calibration phase ensures a series of K weldings is performed, under optimized conditions, for each a number J of spectra OJ,K, is acquired, each one corresponding to a vector of N intensity values at wavelengths ?i, 1?i?N, and a series of weldings K? is then performed, (K??K), a single welding parameter A is altered by a known quantity, for each welding being acquired a sequence of J? spectra AJ?,K?, (J??J), which are stored.Type: GrantFiled: August 29, 2011Date of Patent: November 29, 2016Assignee: CONSIGLIO NAZIONALE DELLE RICERCHEInventors: Guido Toci, Roberto Pini
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Patent number: 9488778Abstract: A method for realizing an optical waveguide in a substrate by means of a femtosecond laser system, the waveguide including a birefringence axis tilted by a predetermined angle for at least a segment, is disclosed. The method includes preparing a substrate including a free surface, focusing a femtosecond laser beam into the substrate, in order to induce a refractive index modification of a volume of such substrate around the focal region. The method further includes varying a propagation direction of the femtosecond laser beam to reach a propagation direction describing a predetermined non-vanishing angle with respect to the normal to the free surface of the substrate, and translating the focal region with respect to the substrate, in order to generate the waveguide segment.Type: GrantFiled: April 18, 2014Date of Patent: November 8, 2016Assignees: CONSIGLIO NAZIONALE DELLE RICERCHE, SAPIENZA UNIVERSITA' DI ROMAInventors: Roberto Osellame, Andrea Crespi, Giacomo Corrielli, Fabio Sciarrino
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Patent number: 9445869Abstract: A microwave surgical device with high energy efficiency produces, at an antenna, an asymmetric heating pattern directed towards the side and it comprises: a plain curved portion extending from the distal end of said external conductor; and an inflection point at said distal end of the external conductor, so that said curved portion has a single cavity directed towards the axis of the coaxial end part.Type: GrantFiled: May 16, 2011Date of Patent: September 20, 2016Assignee: CONSIGLIO NAZIONALE DELLE RICERCHEInventor: Iginio Longo
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Patent number: 9448290Abstract: A hyperpolarization and multiple irradiation probe head, suitable for use in connection with magnetic resonance techniques (DNP-NMR, photo-DNP-NMR, ENDOR-EPR, MRI, DNP-MRI), comprising a RF transducer for generating and detecting a RF signal, wherein said RF transducer has a conducting element (2) allowing, together with at least one fully or partially connected grid polarizer made of conducting grid elements (1) which are reciprocally spaced so as the grid is at least partially transparent to a given microwave beam (3), controlled RF current paths and a substantially uniform RF magnetic field inside the RF transducer, wherein the grid polarizer (1) and the conducting element (2) forming the RF transducer are shaped and oriented to conform to said microwave beam phase fronts, said grid polarizer and said conducting element surrounding a sample (8), which is apt to be irradiated also by said microwaves (3); the probe head being also suited for a simultaneous irradiation of the sample with THz, FIR, IR, visibleType: GrantFiled: June 27, 2012Date of Patent: September 20, 2016Assignee: CONSIGLIO NAZIONALE DELLE RICERCHEInventors: Giuseppe Annino, Alessandro Macor, Emile De Rijk, Stefano Alberti
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Publication number: 20160242449Abstract: The subject-matter of the invention is a food composition derived from ass's milk, which is useful in the feeding of premature babies, weak and/or delicate and/or convalescent subjects and/or the elderly.Type: ApplicationFiled: October 14, 2014Publication date: August 25, 2016Applicants: Consiglio Nazionale Delle Ricerche, Universita ' Degli Studi di TorinoInventors: Amedeo Conti, Guido Moro, Laura Cavallarin, Enrico Bertino
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Publication number: 20160245846Abstract: A method for measuring an alternating electric field is disclosed. The method includes realizing a first diffraction grating in a first location, in a core of a silica-based optical fiber, and measuring a peak reflection wavelength of the first diffraction grating. The method also includes positioning the optical fiber along a direction having a non-zero component of an electrical field generated by an alternating voltage to be measured, and coupling a substantially monochromatic light to said optical fiber surrounded by the electric field. The method further includes measuring a parameter dependent on a shift of the peak reflection wavelength due to intrinsic mechanical deformation or refractive index change of the material in which the optical fiber and the diffracting grating are realized due to the alternating electric field, and calculating a value of the electric field causing such a measured deformation or refractive index change.Type: ApplicationFiled: October 9, 2014Publication date: August 25, 2016Applicants: CNR-CONSIGLIO NAZIONALE DELLE RICERCHE, LEDA SRL, LABORATORIO DI ELETTRODINAMICA AVANZATAInventors: Gianluca GAGLIARDI, Fabrizio MARIGNETTI
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Patent number: 9414789Abstract: A diagnostic device for morpho-functional investigations includes a plurality of measuring elements (5, 6, 7, 8, 9) of the scintillation type, positioned around a receiving area (3) for performing relative three-dimensional investigations on different parts of a patient (P) positioned in the receiving area, the first ring (5) having an internal diameter (d) less than the internal diameter (D) of the second ring (6).Type: GrantFiled: October 11, 2012Date of Patent: August 16, 2016Assignee: CONSIGLIO NAZIONALE DELLE RICERCHE (C.N.R.)Inventors: Alessandro Soluri, Roberto Massari
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Patent number: 9408583Abstract: A portable gamma camera includes a containment body (2), a scintillation measuring structure (3) housed in the containment body (2), a collimator (4) associated with the measuring structure (3), a display (5) positioned on the containment body (2) and an electronic controller unit (6), operating between the measuring structure (3) and the display (5) for generating on the display (5) images representing the radiation intercepted by the measuring structure (3).Type: GrantFiled: October 15, 2013Date of Patent: August 9, 2016Assignee: CONSIGLIO NAZIONALE DELLE RICERCHE (CNR)Inventors: Alessandro Soluri, Roberto Massari
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Patent number: 9355474Abstract: An automatic or semiautomatic method of processing intravascular Optical Coherence Tomography (OCT) images, comprising: pre-processing the primary image by segmenting the guidewire in the lumen to exclude it from the image, determining whether the lumen is open or closed; if the lumen is determined to be closed, performing a first automatic lumen segmentation procedure on the pre-processed image to define a perimeter line of the lumen, corresponding to the inner edge of the vessel wall, and determine a centroid CL of the lumen area; if the lumen is determined not to be closed, sequentially performing an automatic lumen closing procedure on the pre-processed image, and a second automatic lumen segmentation procedure, to define a perimeter line of the lumen, corresponding to the inner edge of the vessel wall, and determine a centroid CL of the lumen area; automatically finding an outer edge of the vessel wall and defining a first region of interest ROI1 between the inner edge and the outer edge of the lumen; auType: GrantFiled: June 28, 2013Date of Patent: May 31, 2016Assignees: Consiglio Nazionale delle Ricerche, Fondazione Toscana Gabriele Monasterio per IA Ricerca Medica e di Sanita PubblicaInventors: Simona Celi, Sergio Berti
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Patent number: 9351983Abstract: The present invention refers to glycerophosphoinositols (GPIs) and derivatives thereof for use in the treatment of pathologies related to a Lipopolysaccharide (LPS)-activated tissue-factor (TF) activity, as pathologies induced by high bacteremia, i.e. septic shock.Type: GrantFiled: October 4, 2013Date of Patent: May 31, 2016Assignee: CONSIGLIO NAZIONALE DELLE RICERCHEInventors: Daniela Corda, Pasquale Zizza, Alberto Luini, Stefania Mariggio'
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Patent number: 9327027Abstract: The present invention relates to hydroxyapatite doped with Fe2+ ions and Fe3+ ions which partially substitute the calcium ions in the crystal lattice. The hydroxyapatite is characterized by an intrinsic magnetism of 0.05 to 8 emu/g, measured by applying a magnetic field of 34 Oe, due to the presence of magnetic nano-domains in the crystal lattice of HA, given the limited amount of magnetic secondary phases present, less than about 3% by volume. The intrinsically magnetic hydroxyapatite can be loaded with biological substances selected in the group consisting of proteins, genes, stem cells, growth factors, vascularization factors, active substances and drugs, under the control of an external magnetic field, as a carrier and release agent for biological substances or drugs, as a contrast agent in diagnostics or for bone or osteocartilage regeneration.Type: GrantFiled: July 28, 2011Date of Patent: May 3, 2016Assignees: CONSIGLIO NAZIONALE DELLE RICERCHE, UNIVERSIDADE DE SANTIAGO DE COMPOSTELA, FIN-CERAMICA FAENZA S.P.A.Inventors: Anna Tampieri, Elena Landi, Monica Sandri, Daniele Pressato, José Rivas Rey, Manuel Banobre López, Maurilio Marcacci
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Patent number: 9327976Abstract: The present invention relates to a hydroxyapatite multi-substituted with, physiologically compatible ion species and to its biohybrid composite with a natural and/or synthetic polymer, which are useful in the preparation of a biomimetic bone substitute for treating bone tissue defects. Furthermore, the present invention relates to a method for their preparation and uses.Type: GrantFiled: October 12, 2006Date of Patent: May 3, 2016Assignees: C.N.R. CONSIGLIO NAZIONALE DELLE RICERCHE, FIN-CERAMICA FAENZA S.P.A.Inventors: Elena Landi, Anna Tampieri, Giancarlo Celotti, Simone Sprio, Daniele Pressato, Claudio De Luca
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Patent number: 9326948Abstract: The present invention relates to a bone substitute comprising a core based on hydroxyapatite (HA), obtained from at least one porous wood, or based on collagen fibers and hydroxyapatite, and a shell, based on hydroxyapatite (HA) or silicon carbide (SiC), obtained from at least one wood having a lower porosity than the at least one wood of the core. The porous wood has a total porosity of between 60% and 95%, preferably between 65% and 85%, and it is selected from amongst the choices of rattan, pine, abachi and balsa wood. The wood of the shell has a porosity of between 20% and 60%, preferably between 30% and 50%. The bone substitute is utilized for the substitution and regeneration of bone, preferably for bones subjected to mechanical loads, such as long bones of the leg and arm, preferably the tibia, metatarsus, femur, humerus or radius.Type: GrantFiled: November 8, 2011Date of Patent: May 3, 2016Assignee: CONSIGLIO NAZIONALE DELLE RICERCHEInventors: Anna Tampieri, Simone Sprio, Andrea Ruffini, Julia Will, Peter Greil, Frank Muller, Julian Martinez Fernandez, Carmen Torres Raya, Francisco Manuel Varela Feria, Joaquin Ramirez Rico, Marie-Francoise Harmand
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Patent number: 9322775Abstract: The present invention relates to a method and an apparatus to perform frequency comb spectroscopy.Type: GrantFiled: December 28, 2012Date of Patent: April 26, 2016Assignee: CNR—CONSIGLIO NAZIONALE DELLE RICERCHEInventors: Gianluca Gagliardi, Saverio Avino, Antonio Giorgini, Paolo De Natale
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Patent number: 9314391Abstract: A joint for articulations with pseudo-elastic elements comprising a pair of coupled box-shaped elements (13, 14), facing each other in an open surface, moveable and rotating with respect to each other, around a common longitudinal axis (15) and containing a spring-charged pseudo-elastic element (12) which causes the reciprocal rotation, the box-shaped elements (13, 14) carrying an arm (20, 25) facing outwardly for connection with associated portions of an articulation and including stop elements (21, 32; 132, 20) of their rotation. The spring-charged pseudo-elastic element (12) comprises a curved portion, more or less closed to form a ring (36) and two straight portions (37) terminating in ends (23, 34), inserted into holes (22, 33) of the box-shaped elements (13, 14), the straight portions (37) being intersected to obtain a pre-charge before being inserted into the holes (22, 33).Type: GrantFiled: May 2, 2011Date of Patent: April 19, 2016Assignee: CONSIGLIO NAZIONALE DELLE RICERCHEInventors: Simone Pittaccio, Stefano Viscuso, Stefano Besseghini
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Publication number: 20160076518Abstract: A method and system for converting mechanical energy from a generator operated by a turbine into electric energy to be input into an electric network, comprising the following: (A) supplying a power electronic converter connectable to input of the generator and to output of the electric network; (B) supplying an electrical power outputting the generator to the power electronic converter; (C) adapting the electrical power using the power electronic converter to input the electrical power to the electric network by the following substeps: (C1) calculating rotation speed of the turbine; (C2) calculating wind speed moving the turbine; (C3) calculating reference rotation speed, corresponding to the maximum point of power input to the electric network, using a Maximum Power Point Tracking algorithm; the method comprising substep (C1) implemented by an algorithm carrying out a virtual encoder, and substep (C2) implemented by training a neural network implementing a virtual anemometer.Type: ApplicationFiled: May 5, 2014Publication date: March 17, 2016Applicant: CONSIGLIO NAZIONALE DELLE RICERCHEInventors: Gianpaolo VITALE, Marcello PUCCI, Massimiliano LUNA
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Patent number: 9274841Abstract: Assigning of application-hosting virtual machines to a plurality of servers inclusive of active and inactive servers in a data or calculation center is described.Type: GrantFiled: August 8, 2012Date of Patent: March 1, 2016Assignees: CONSIGLIO NAZIONALE DELLE RICERCHE, UNIVERSITA DELLA CALABRIAInventors: Domenico Talia, Carlo Mastroianni, Agostino Forestiero, Giuseppe Papuzzo, Raffaele Giordanelli
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Publication number: 20160054180Abstract: The present invention relates to a ring-down spectrometry apparatus in absorption saturation condition, for measuring the concentration of a gas through a measurement of the spectrum of a molecular transition of said gas. The apparatus includes a laser source, an adjuster for varying the wavelength of said radiation emitted by said laser, and a resonant cavity. A photodetector is adapted to detect an electromagnetic radiation beam and is adapted to generate a decay signal. An electronic circuit receives the signal from the photodetector and is adapted to convert it to a processor. A processor is adapted to receive said decay signal from the photodetector and perform interpolation to obtain a concentration of said gas.Type: ApplicationFiled: April 15, 2014Publication date: February 25, 2016Applicant: CONSIGLIO NAZIONALE DELLE RICERCHEInventors: Giovanni Giusfredi, Iacopo Galli, Pablo Cancio Pastor, Davide Mazzotti, Paolo De Natale