Patents Assigned to NAZIONALE DELLE RICERCHE
  • Patent number: 9052372
    Abstract: A method of generating 2D or 3D maps of MRI T1 and T2 relaxation times by acquiring 2D or 3D MRI gradient-echo images and extracting the T1 and T2 values from the images, wherein MRI images are acquired using a combination of gradient-echo sequences, including a first MRI image acquired using a SSFP-FID (Steady State Free Precession-Free Induction Decay) acquisition sequence; two further images acquired using a Dual-Echo SSFP acquisition sequence; and the T1 and T2 values are extracted for each image pixel or voxel from the corresponding MRI signals.
    Type: Grant
    Filed: March 1, 2012
    Date of Patent: June 9, 2015
    Assignees: ESAOTE S.P.A., CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Guiseppe Palma, Danilo Greco, Stefania Innocenti, Bruno Alfano
  • Publication number: 20150123703
    Abstract: A logic gate (1) comprising a spintronic memristor device (2), which has two spin-polarized magnetic electrodes (3, 4) for injecting and/or receiving a spin-polarized current and a layer of material (5) interposed between the two electrodes (3, 4) for transporting the spin-polarized current from one electrode to the other. The layer of material (5) is composed of a layer of organic semiconductor that is able to endow the spintronic memristor device (2) with at least two non-volatile electrical resistance states (RH, RL), each of which can be selected by applying a voltage to the electrodes (3, 4) that reaches or exceeds a respective voltage threshold (VT1, VT2) and, in at least a first resistance state (RH) of which, the spintronic memristor device (2) does not present a magnetoresistive effect.
    Type: Application
    Filed: October 5, 2012
    Publication date: May 7, 2015
    Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Valentin Alek Dediu, Mirko Prezioso, Alberto Riminucci, Ilaria Bergenti, Patrizio Graziosi
  • Patent number: 9007237
    Abstract: Lighting devices are provided including those which have an array of spatially distributed optoelectronic sources, each source being adapted to emit a respective incident optical beam; a first reflector having an optical axis, and having a first reflective surface that is concave and facing the array of sources to intercept said incident optical beams and to produce corresponding reflected optical beams; a second reflector having a second reflective surface interposed along said optical axis between said array of optoelectronic sources and the first reflector adapted to intercept and deflect said reflected optical beams producing corresponding deflected optical beams, the first reflector being adapted to concentrate the reflected optical beams on the second reflective surface.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: April 14, 2015
    Assignee: Consiglio Nazionale Delle Ricerche
    Inventors: David Jafrancesco, Luca Mercatelli, Paola Sansoni, Daniela Fontani, Elisa Sani, Franco Francini
  • Patent number: 8999655
    Abstract: The present invention relates to a method for the diagnostic and/or prognostic of a neurological disease characterized by an inflammation process in a subject comprising measuring the amount of myeloid derived microvesicles in a cerebrospinal fluid sample obtained from the subject. The invention further relates to a method for predicting and/or monitoring the efficacy of a treatment for a neurological pathology or for monitoring a neurological disease progression.
    Type: Grant
    Filed: March 3, 2011
    Date of Patent: April 7, 2015
    Assignees: Consiglio Nazionale delle Ricerche, Universita degli Studi di Milano, Ospedale San Raffaele S.r.l.
    Inventors: Claudia Verderio, Michela Matteoli, Roberto Furlan
  • Publication number: 20150086608
    Abstract: A porous polymeric matrix and a device for optically-controlled release of chemicals allow a controlled and localized administration of a chemical species, by exploiting the thermosensitivity of amphiphilic supramolecular structures used as reservoir without this requesting a direct heating, at the same time by guaranteeing a precise dosage and positioning of the release of the chemical species.
    Type: Application
    Filed: April 17, 2013
    Publication date: March 26, 2015
    Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Paolo Matteini, Fulvio Ratto, Roberto Pini
  • Patent number: 8948561
    Abstract: A waveguide is provided on which an electromagnetic wave impinges, the electromagnetic wave having a wavelength ? included in a given interval ?? of interest centered on a ?centr. The waveguide comprises a film defining a surface on a plane on which the electromagnetic waves are apt to impinge, having a thickness in a direction substantially perpendicular to the surface, the film being realized in a material having a first refractive index; a plurality of scatterers being randomly distributed in two directions in at least a portion of the surface of the film, the scatterers having a substantially constant cross section along said substantially perpendicular direction. The scatterers are realized in a material having a second refractive index lower than the first refractive index, wherein the wavelength of the incident electromagnetic waves is comprised between 0.
    Type: Grant
    Filed: September 2, 2010
    Date of Patent: February 3, 2015
    Assignee: CNR—Consiglio Nazionale Delle Ricerche
    Inventors: Diederik Sybolt Wiersma, Francesco Riboli, Kevin Vynck, Matteo Burresi
  • Publication number: 20150031193
    Abstract: A semiconductive substrate (1) is described that is suitable for realising electronic and/or optoelectronic devices of the type comprising at least one substrate (3), in particular of single crystal silicon, and an overlying layer of single crystal silicon (5). Advantageously, according to the invention, the semiconductive substrate (1) comprises at least one functional coupling layer (10) suitable for reducing the defects linked to the differences in the materials used. In particular, the functional coupling layer 10 comprises a corrugated portion (6) made in the layer of single crystal silicon (5) and suitable for reducing the defects linked to the differences in lattice constant of such materials used.
    Type: Application
    Filed: October 14, 2014
    Publication date: January 29, 2015
    Applicant: Consiglio Nazionale Delle Ricerche
    Inventors: Guiseppe Alessio Maria D'Arrigo, Francesco LA VIA
  • Publication number: 20140378876
    Abstract: A device (7) for the rehabilitation of the movements of the foot (1) includes a supporting base (8) and a mobile platform (9) with a supporting surface (10) for resting the sole of the foot (1), wherein the mobile platform (9) is secured to the supporting base (8) by a pure rotation movement mechanism (12) with three degrees of freedom of rotary movement independent the one from the other and placed in parallel which allow rotations of the mobile platform around three axes (13, 14, 15) which intersect one another in a single rotation center (P). The supporting surface (10) is turned towards the rotation center (P) and is distant from the rotation center (P) in such a way that the rotation center (P) is positioned in correspondence to the ankle (2) of the foot (1).
    Type: Application
    Filed: December 19, 2012
    Publication date: December 25, 2014
    Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Matteo Malosio, Simone Pio Negri, Nicola Pedrocchi, Marco Caimmi, Federico Vicentini, Lorenzo Tosatti Molinari
  • Patent number: 8916717
    Abstract: The invention relates to dioxaspiroketal derivatives of formula (I): wherein R, is selected from the group consisting of H, straight or branched chain C1-C6 alkyl, C1-C6 alkoxy, C2-C6 alkenyl, cycloalkyl, heterocyclyl, phenyl, optionally para-, meta- or ortho-substituted with 0 to 3 substituent selected from halogen, —CN, —NH2, —OH, —NO2, COOR2, wherein R2 is selected from H and C1-C6 alkyl, n is 1 or 2, X is O or S, R1 is selected from H, OH, halogen, C1-C6 alkyl, C1-C6 alkoxy, COOR3, wherein R3 is selected from H and C1-C6 alkyl, or physiologically acceptable salts thereof, process for preparation thereof, their uses in medical field, in particular as anti-tumor medicaments.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: December 23, 2014
    Assignee: Consiglio Nazionale Delle Ricerche
    Inventors: Antonella DeMico, Andrea Cottarelli, Mariapia Fuggetta, Giulia Lanzilli, Maria Tricarico
  • Patent number: 8890103
    Abstract: A semiconductive substrate that is suitable for realising electronic and/or optoelectronic devices that include at least one substrate, in particular of single crystal silicon, and an overlying layer of single crystal silicon. Advantageously, the semiconductive substrate comprises at least one functional coupling layer suitable for reducing the defects linked to the differences in the materials used. The functional coupling layer can comprise a corrugated portion made in the layer of single crystal silicon and suitable for reducing the defects linked to the differences in lattice constant of such materials used. Alternatively, the functional coupling layer can comprise a porous layer arranged between the substrate of single crystal silicon and the layer of single crystal silicon, and suitable for reducing the stress caused by the differences between the thermal expansion coefficients of the materials used. A manufacturing process of such a semiconductive substrate is also described.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: November 18, 2014
    Assignee: Consiglio Nazionale Delle Ricerche
    Inventors: Giuseppe Alessio Maria D'Arrigo, Francesco La Via
  • Publication number: 20140312879
    Abstract: A transistor includes at least one conductive layer, at least one gate dielectric layer and at least one semiconducting film deposited on top of a receptor molecule layer previously deposited or covalently linked to the surface of the gate dielectric. The layer of biological material includes single or double layers of phospholipids, layers made of proteins such as receptors, antibodies, ionic channels and enzymes, single or double layers of phospholipids with inclusion or anchoring of proteins such as: receptors, antibodies, ionic channels and enzymes, layers made of oligonucleotide (DNA, RNA, PNA) probes, layers made of cells or viruses, layers made of synthetic receptors for example molecules or macromolecules similar to biological receptors for properties, reactivity or steric aspects.
    Type: Application
    Filed: October 31, 2011
    Publication date: October 23, 2014
    Applicants: UNIVERSITÁ DEGLI STUDI DI BARI, Consiglio Nazionale delle Ricerche Istituto Pro- cessi Chimico Fisici-IPCF
    Inventors: Luisa Torsi, Gerardo Palazzo, Nicola Cioffi, Maria Daniela Angione, Maria Magliulo, Serafina Cotrone, Gaetano Scamarcio, Luigia Sabbatini, Antonia Malllardi
  • Publication number: 20140305510
    Abstract: A device for controlling liquid motion includes a substrate (10) of material having piezoelectric properties, and a system for controlling the motion of a quantity of liquid placed in contact with the substrate. The control system includes at least one interdigitated transducer (T1, T3, T5, T7), applied to the substrate (10) and designed for selectively generating a surface acoustic wave adapted to propagate on the substrate (10) and interact with the quantity of liquid. The control system further includes an acoustic resonator (30) which is placed on the path of the surface acoustic wave, and which is adapted to normally allow the forward transmission of the surface acoustic wave having a frequency equal to a resonance frequency of the acoustic resonator, and to reflect the surface acoustic wave back towards the transducer when the quantity of liquid is present within the acoustic resonator.
    Type: Application
    Filed: October 10, 2012
    Publication date: October 16, 2014
    Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Vincenzo Piazza, Giorgio De Simoni, Marco Cecchini, Marco Travagliati, Fabio Beltram
  • Patent number: 8859599
    Abstract: The present invention concerns compounds of general formula (I): Method of preparation and uses thereof.
    Type: Grant
    Filed: February 11, 2010
    Date of Patent: October 14, 2014
    Assignees: CNR—Consiglio Nazionale delle Ricerche, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.) S.r.l.
    Inventors: Greta Varchi, Andrea Guerrini, Anna Tesei, Giovanni Brigliadori
  • Patent number: 8840557
    Abstract: An apparatus (10) for measuring one or more labor progress parameters (25) as the dilation of the endocervical canal (8), the rotation and the position of the head (4) of the foetus (3) during the descent, the duration and the intensity of the uterine contractions, other morphological and physiological parameters, without introducing foreign objects into the body of a pregnant woman (2) and independently from the sensitivity of the operator. The apparatus (10) comprises automatic means for tracking, in a sequence of ultrasound images (11,12) that are obtained by an ultrasound probe (1), one or more regions of interest (ROI, 21), that may be both two-dimensional or three-dimensional and are centered about anatomic reference points (28) that define said parameters selected in a reference image by a displaying unit (14).
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: September 23, 2014
    Assignee: CNR—Consiglio Nazionale delle Ricerche
    Inventors: Sergio Casciaro, Ernesto Casciaro, Francesco Conversano
  • Publication number: 20140264385
    Abstract: A method is provided for fabricating a wafer of semiconductor material intended for use for the integration of electronic and/or optical and/or optoelectronic devices. The method comprises: providing a starting wafer of crystalline silicon (205); on the starting wafer of crystalline silicon, epitaxially growing a buffer layer (210) consisting of a sub-stoichiometric alloy of silicon and germanium; epitaxially growing on the buffer layer a layer (225) of a semiconductor material having an energy gap greater than that of the crystalline silicon constituting the starting wafer, wherein the layer of semiconductor material having an energy gap greater than that of the crystalline silicon is grown so to have a thickness capable of constituting a substrate for the integration therein of electronic and/or optical and/or optoelectronic devices.
    Type: Application
    Filed: July 25, 2012
    Publication date: September 18, 2014
    Applicant: Consiglio Nazionale delle Ricerche
    Inventors: Camarda Massimo, Andrea Severino, Francesco La Via
  • Publication number: 20140265830
    Abstract: A UV lamp includes a UV lamp unit including a tubular bulb and an antenna inserted in the tubular bulb, and an antenna lead for supplying microwave energy from a microwave energy source to the UV lamp unit.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Applicants: CONSIGLIO NAZIONALE DELLE RICERCHE, HERAEUS NOBLELIGHT FUSION UV INC.
    Inventors: Pradyumna Kumar SWAIN, Andrew David Paul HARBOURNE, Iginio LONGO, Carlo FERRARI
  • Publication number: 20140228448
    Abstract: The present invention relates to the use of R—OH alcohols as phagodeterrents, and to a method for treating plants infested with aphids which comprises the administration of these R—OH alcohols.
    Type: Application
    Filed: May 14, 2012
    Publication date: August 14, 2014
    Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Maria Agnese Sabatini, Sonia Ganassi, Claudio Altomare, Mara Favilla, Antonio Evidente, Anna Andolfi
  • Patent number: 8801639
    Abstract: A biomedical device (1) for robotized rehabilitation of a human upper limb, particularly for neuromotor rehabilitation of the shoulder and elbow joint, includes a first rigid rod (2) and a second rigid rod (3), both of which can be associated with the upper limb (4) of a patient (5) and are articulated to each other at two adjacent ends (2a, 3a) thereof by way of a first universal joint (6) which can be arranged proximate to the elbow joint (7) of the upper limb (4).
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: August 12, 2014
    Assignee: C.N.R. Consiglio Nazionale Delle Ricerche
    Inventors: Matteo Malosio, Nicola Pedrocchi, Lorenzo Molinari Tosatti
  • Patent number: 8795262
    Abstract: A method of suturing the lens capsule of the eye in the event of accidental rupture thereof or to create a valve and/or to close a capsulorhexis by laser-induced welding onto the capsule's surface of a flap of biocompatible biological tissue prepared so as to be optically absorbent at the wavelength of the laser being used for welding. The method is suitable for use in so-called Phaco-Ersatz or “lens refilling” ophthalmologic surgery. Welding is desirably performed using laser devices that comprise a laser generator and a fiberoptic system for conveying the laser beam, complete with an applicator handpiece suitable for use in welding the flaps onto the lens capsule in a liquid environment. The handpiece is shaped so as to exert moderate pressure on the tissues to be welded with the free end of the optic fiber.
    Type: Grant
    Filed: August 30, 2005
    Date of Patent: August 5, 2014
    Assignees: Azienda USL 4 Prato, Consiglio Nazionale Delle Ricerche
    Inventors: Roberto Pini, Luca Menabuoni, Ivo Lenzetti, Francesca Rossi, Jean-Marie Parel
  • Publication number: 20140184779
    Abstract: A microscopy optoelectronic device for reconstructing a three-dimensional model of a sample, which can be connected to any PC in order to obtain three-dimensional surface micro-reliefs, includes a portable device body, having a casing and a frame supporting: a digital optical sensor; an optical group, coupled to the sensor including an objective lens directed towards a distal end of the device body, faceable towards the sample; a motor that translates the optical group and sensor with respect to said frame; a connector to connect the device body to an energy source and to a device that controls the position of the optical group and to transmit the digitalized images; and a light source that provides diffused lighting at the objective lens arranged to surround a front region with respect to the objective lens and also includes a luminescent and diffusing surface having a tubular portion coaxial to the optical group.
    Type: Application
    Filed: July 31, 2012
    Publication date: July 3, 2014
    Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Salvatore Siano, Andrea Azelio Mencaglia, Ilaria Cacciari