Patents Assigned to Nereus Pharmaceuticals, Inc.
  • Patent number: 6358957
    Abstract: A compound, its pharmaceutically acceptable salts, and/or its pro-drug esters, in isolated form, and methods for isolating, for formulating, and for administering the compound, salt, and/or pro-drug ester as an antitumor agent, wherein the compound, salt, or pro-drug ester has the following structure: wherein: R1, R2, R5, R7,and R8 are each separately selected from the group consisting of a hydrogen atom, a halogen atom, and saturated C1-C24 alkyl, unsaturated C1-C24 alkenyl, cycloalkyl, cycloalkenyl, alkoxy, cycloalkoxy, aryl, substituted aryl, heteroaryl, substituted heteroaryl, amino, substituted amino, nitro, substituted nitro, phenyl, and substituted phenyl groups, R3, R4, and R6 are each separately selected from the group consisting of a hydrogen atom, a halogen atom, and saturated C1-C12 alkyl, unsaturated C1-C12 alkenyl, cycloalkyl, alkoxy, cycloalkoxy, aryl, substituted aryl, heteroaryl, substituted heteroaryl, amino, substituted amino, nitro, and substituted nitro groups, X1 and
    Type: Grant
    Filed: November 12, 1999
    Date of Patent: March 19, 2002
    Assignee: Nereus Pharmaceuticals, Inc.
    Inventors: Kenji Fukumoto, Shinkichi Kohno, Kaneo Kanoh, Tohru Asari, Hiroshi Kawashima, Hirokatsu Sekiya, Kazunori Ohmizo, Takeo Harada