Abstract: Compositions for use in the treatment or prevention of influenza infection are provided, and the compositions contain a 2-fucosylated oligosaccharide, such as 2?-fucosyllactose (2?FL). The compositions can also include fructooligosaccharides (FOS). Additionally said compositions can be used for improving resistance to an influenza virus, decreasing influenza in the lung, decreasing influenza-induced anorexia, decreasing influenza-induced pulmonary mucin secretion, and decreasing influenza-induced IgG response. They may be used in a infant or a young child.
Abstract: The present invention provides methods for measuring the total and/or activation levels of one or more analytes such as HER1, HER2, HER3, cMET, IGF-1R, PI3K, AKT, PRAS40, MEK, RSK, JAK1, STAT1, STAT3, TNF?, and/or anti-TNF? drug to determine whether a subject with inflammatory bowel disease (IBD) has non-inflamed and/or non-involved or inflamed and/or involved gastrointestinal tissue. The methods of the present invention can be used to evaluate mucosal healing, to diagnose, prognose, and monitor the progression of IBD, and to select and monitor the therapeutic response to IBD therapy.
Type:
Application
Filed:
June 2, 2016
Publication date:
December 8, 2016
Applicant:
NESTEC S.A.
Inventors:
SHARAT SINGH, KATHERINE DRAKE, ANJALI JAIN, RICHARD KIRKLAND, XINJUN LIU
Abstract: A beverage preparation machine (1) comprises: a beverage preparation module (2) that vibrates during use, in particular a module for preparing a beverage by circulating a liquid via a flavoring ingredient such a pre-portioned ingredient contained in a capsule; and a reservoir (4) for storing liquid and supplying such liquid to the beverage preparation module. The beverage preparation module and the reservoir are connected by a vibration-barrier mechanical connection (3, 45, 291, 431) for inhibiting or preventing propagation of vibrations from the beverage preparation module to the reservoir.
Abstract: The present invention provides compositions, methods, and kits for discriminating sequence variation between different alleles. More specifically, in some embodiments, the present invention provides compositions, methods, and kits for determining the presence and/or level (e.g., quantitating) of rare (e.g., mutant) allelic variants, such as single nucleotide polymorphisms (SNPs) or nucleotide insertions or deletions, in samples comprising abundant (e.g., wild-type) allelic variants with high sensitivity and/or specificity. As such, in certain embodiments, the present invention provides a highly selective method for the detection of somatic mutations, e.g., in samples containing abundant levels of a wild-type allele compared to very low levels of a mutant allele.
Type:
Grant
Filed:
February 18, 2014
Date of Patent:
December 6, 2016
Assignee:
Nestec S.A.
Inventors:
Fred Princen, Fabiyola Selvaraj, Sharat Singh
Abstract: The present invention relates to a beverage preparation machine with ambience emulation functionality. A providing arrangement (11, 21, 17) provides data with visible 5 content for generating a predefined ambience when reproduced, wherein the provided data are linked to context information, said context information being indicative of a situation. An acquisition arrangement (11, 37, 60, 62, 63) acquires at least one actual context 10 information indicating an actual situation, and a display (10) reproduces data being associated to the acquired actual context information for generating an ambience related to the actual situation.
Abstract: The present invention provides assays for detecting and measuring the presence or level of anti-TNF? drug therapeutics and autoantibodies in a sample. The present invention is useful for optimizing therapy and monitoring patients receiving anti-TNF? drug therapeutics to detect the presence or level of autoantibodies (e.g., HACA and/or HAHA) against the drug.
Type:
Grant
Filed:
July 21, 2014
Date of Patent:
November 29, 2016
Assignee:
Nestec S.A.
Inventors:
Sharat Singh, Shui Long Wang, Linda Ohrmund
Abstract: The present invention relates to filling compositions comprising an encapsulated oil, and optionally a free liquid oil. The encapsulated oil comprises at least 40% w/w of a liquid oil encapsulated in a matrix material. The invention also relates to processes for the preparation of the filling composition and its use in composite food products.
Type:
Grant
Filed:
December 23, 2011
Date of Patent:
November 29, 2016
Assignee:
Nestec S.A.
Inventors:
Judith Arfsten, Everton De Padua Chicaroni, Emmanuel Heinrich, James William Outram, Anwesha Sarkar
Abstract: The invention concerns a cultured savory base with increased umami power comprising: up to 80% of naturally derived compounds taken in the group consisting of glutamate, IMP and GMP, naturally food derived compounds such as organic acids, amino acids, peptides and aroma compounds.
Type:
Grant
Filed:
July 17, 2008
Date of Patent:
November 29, 2016
Assignee:
Nestec S.A.
Inventors:
Stefan Palzer, David Nikolic, Pieter Berends, Thang Ho Dac, Yvette Fleury Rey, Helge Ulmer
Abstract: The present invention relates to an efficient method of improving the solubility of zinc in zinc-containing still drinking water so as to extend its shelf life. This method comprises a carbonating step of said still drinking water with a low carbon dioxide concentration.
Abstract: Bifidobacterium breve CNCM I-3865 (NCC2950), a composition comprising Bifidobacterium breve CNCM I-3865 (NCC2950), and the use of Bifidobacterium breve CNCM I-3865 (NCC2950) in the prevention or treatment of allergic diarrhoea are provided. The Bifidobacterium breve CNCM I-3865 (NCC2950) can be in a non-replicating form and can be administered to at least partially treat allergic diarrhoea or at least partially reduce the risk of developing allergic diarrhoea.
Type:
Grant
Filed:
May 7, 2010
Date of Patent:
November 22, 2016
Assignee:
Nestec S.A.
Inventors:
Sophie Nutten, Annick Mercenier, Swantje Duncker
Abstract: The present invention presents a capsule 1 having an inlet face C, which is formed by a circular section 2a and a bulge section 2b extending from the circular section 2a giving the inlet face C a not symmetric in rotation. The capsule 1 further has an optically readable code 3 on a side wall 4 of a cup-shaped body of the capsule 1 opposite the bulge section 2b. The present invention further presents a beverage production machine with a capsule holder 13 for holding a capsule 1 in such a way in the beverage production machine 10, that the optically readable code can be read by a code reader 24. Liquid can be supplied to the capsule to produce a nutritional product. The present invention provides means to prevent the optically readable code 3 and the code reader 24, respectively, from being contaminated with liquid, vapor, dirt or the like.
Type:
Grant
Filed:
November 10, 2011
Date of Patent:
November 22, 2016
Assignee:
Nestec S.A.
Inventors:
Ines Magniet, Yann Epars, Vincent Martin, Heinz Wyss, Raphael Bernhardsgruetter, Roland Lehmann
Abstract: The present invention relates generally to the field of nutrition and health. In particular, the present invention relates to a new biomarker, its use and a method that allows it to diagnose the likelihood to resist diet induced weight gain, and/or to be susceptible to a diet induced weight gain. For example, the biomarker may be isovalerylglycine.
Type:
Grant
Filed:
November 25, 2013
Date of Patent:
November 22, 2016
Assignee:
Nestec S.A.
Inventors:
Francois-Pierre Martin, Claire L. Boulange, Ivan Montoliu Rora, Sebastiano Collino, Marc-Emmanuel Dumas, Elaine Holmes, Serge Andre Dominique Rezzi, Jeremy Nicholson, Sunil Kochhar
Abstract: The present invention provides methods for predicting post-operative recurrence of Crohn's disease (CD) in a subject. With the present invention it is possible to predict whether a patient undergoing surgical treatment of CD is at risk of developing histological, radiographic, endoscopic, and/or clinical recurrence of the disease.
Type:
Application
Filed:
May 20, 2016
Publication date:
November 17, 2016
Applicants:
NESTEC S.A., UNIVERSITY HOSPITALS LEUVEN
Inventors:
STEVEN LOCKTON, MARC FERRANTE, SEVERINE VERMIERE, SHARAT SINGH
Abstract: The present invention relates generally to the field of food supplements and/or food products for cosmetic purpose. More specifically, the present invention aims to provide an ingredient containing caftaric acid and/or derivatives for preventing and/or treating hyper-pigmentation of skin, skin color imperfections such as age-spots and other skin disorders characterized by abnormal pigments. The present invention also aims at improving skin tone as well as providing a skin lightening agent.
Abstract: The present invention relates generally to the field of food supplements for cosmetic purpose. More specifically, the present invention aims to provide an ingredient containing chicoric acid and/or derivatives for preventing and/or treating hyper-pigmentation of skin, skin color imperfections such as age-spots and other skin disorders characterized by abnormal pigments. The present invention also aims at improving skin tone as well as providing a skin lightening agent.
Abstract: Nutritional products and methods for modulating off-taste intensity in nutritional products are provided. In a general embodiment, a nutritional product is provided and includes a blend of carbohydrates in an approximate 1 to 1 to 1 weight ratio. The blend of carbohydrates may include maltodextrin, corn syrup, and sugar. In another embodiment, methods for modulating off-taste intensity of nutritional compositions are provided and include modifying the sweetness of the nutritional product so that it is moderate.
Abstract: The present invention relates generally to the field of cosmetic and/or food supplement. More specifically, the present invention aims to provide the use of at least an ingredient containing caftaric acid and/or derivatives and a micro-organism and/or an enzyme capable of hydrolyzing caftaric acid and/or derivatives thereof to generate tartaric and/or caffeic acid, for improving skin tone and preventing and/or treating hyper-pigmentation of skin and/or skin color imperfections such as age-spots and other skin disorders characterized by abnormal pigments. Also, the present invention aims at providing a skin lightening agent.
Abstract: Use of a pomegranate skin extract for use in the treatment of metabolic syndrome, more particularly, fatty liver disease. More particularly, the pomegranate skin extract is used in inhibiting body weight gain in the prevention and/or the treatment of fatty liver disease in mammals.
Abstract: The present invention relates to a capsule (1) for containing beverage ingredients intended to produce a beverage in a beverage preparation device (20) upon liquid injection into the capsule and by rotating the capsule around its central axis in the device (20), the capsule (1) comprising: a side wall (2a), a bottom wall (2b) and a flange-like rim (2c), an upper wall (3) attached to the flange-like rim (2c) and/or the side wall (2b) of the capsule (1), the upper wall (3) comprising a central liquid inlet (4) and peripheral outlet apertures (5), wherein the upper wall (3) further comprises an outwardly protruding sealing member (6) which is arranged at an annular portion (3a) of the upper wall (3) between the central liquid inlet (4) and the peripheral outlet apertures (5), and which is designed to at least significantly hinder, preferably prevent liquid from flowing at the outside of the capsule (1) from the liquid inlet (4) to the outlet apertures (5) when the sealing member is engaged by the beverage prepar
Type:
Grant
Filed:
October 26, 2012
Date of Patent:
November 8, 2016
Assignee:
Nestec S.A.
Inventors:
Alexandre Perentes, Daniel Abegglen, Arnaud Gerbaulet, Jean-Francois Tinembart, Bruno Bizet, Nicolas Jean-Guy Bezet
Abstract: The present invention relates generally to compositions with a health benefit. In particular, the invention relates to treatment or prevention of liver disorders. A subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of liver disorders. A further subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of liver disorders linked to an insufficient activity of phase II enzymes in the liver.
Type:
Grant
Filed:
March 25, 2013
Date of Patent:
November 8, 2016
Assignee:
Nestec S.A.
Inventors:
Francia Jacqueline Arce Vera, Bertrand Bourqui, Timo Buetler, Stephane Duboux, Francis Foata, Philippe Alexandre Guy, Nicolas Page, Serge Andre Dominique Rezzi