Abstract: The invention provides a method for producing a terpene or a precursor thereof by microbial fermentation. Typically, the method involves culturing a recombinant bacterium in the presence of a gaseous substrate whereby the bacterium produces a terpene or a precursor thereof, such as mevalonic acid, isopentenyl pyrophosphate, dimethylallyl pyrophosphate, isoprene, geranyl pyrophosphate, farnesyl pyrophosphate, and/or farnesene. The bacterium may comprise one or more exogenous enzymes, such as enzymes in mevalonate, DXS, or terpene biosynthesis pathways.

Abstract: The present invention relates to methods for the screening, identification and/or application of microorganisms and/or compositions of use in imparting beneficial properties to plants, and microorganisms and compositions identified therefrom.

Abstract: The invention provides animal feed comprising microbial biomass and methods of producing animal feed by culturing a microorganism to produce microbial biomass. In particular, the invention relates to animal feed produced by fermentation of a gaseous substrate comprising one or more of CO, CO2, and H2, especially by a Gram-positive, anaerobic, and/or Clostridium microorganism.

Abstract: The present invention relates to a composition, the composition including a therapeutically effective amount of at least one active agent, and a base including, an amount of colloidal silica; at least one oil; and at least one surfactant, wherein the viscosity of the composition is below 1000 mPas at a shear rate of 100 l/s and at a temperature of 20° C.

Abstract: The invention provides processes and methods for utilization of carbon dioxide (CO2) in the fermentation of a gaseous substrate comprising hydrogen (H2) and CO2. In particular, the invention allows for the conversion of at least a portion of the CO2 in the gaseous substrate to one or more products, such as ethanol, acetate, and/or 2,3-butanediol.

Abstract: This invention is directed in part to novel doses, dosage formulations, and routes of administration of such doses and dose formulations, said dose and dose formulations containing one or more copper chelators, for example, one or more trientine active agents, including trientine analogues, trientine salts, trientine prodrugs, and trientine derivatives, useful in the treatment of diseases, disorders and conditions, including in indications where copper may play a role.

Abstract: This invention relates generally to method for producing products, particularly alcohols, by microbial fermentation. In particular, the invention relates to methods for increasing the efficiency of the fermentation, by providing a method for treating the used fermentation broth to produce a treated permeate which is then passed back to the bioreactor. The invention provides a method whereby at least one treatment step used to treat the permeated, produces a gaseous product which is then used in one or more stages of the fermentation process.

Abstract: The invention provides a recombinant, carboxydotrophic Clostridium bacterium that expresses one or more of pyruvate:ferredoxin oxidoreductase (EC 1.2.7.1), acetolactate synthase (EC 2.2.1.6), and acetolactate decarboxylase (EC 4.1.1.5). The invention further provides a method of producing a fermentation product by fermenting the recombinant bacterium in the presence of a gaseous substrate comprising CO to produce one or more of ethanol, butanol, isopropanol, isobutanol, higher alcohols, butanediol, 2,3-butanediol, succinate, isoprenoids, fatty acids, biopolymers, and mixtures thereof.

Abstract: The invention provides methods and systems for the production of lipid products from a gaseous substrate using a two stage fermentation process. The method comprises providing a gaseous substrate comprising CO, CO2 or H2 or mixtures thereof, to a first bioreactor containing a culture or one or more microorganisms, and fermenting the substrate to produce acetate. The acetate from the first bioreactor is then provided to a second bioreactor, where it is used as a substrate for fermentation to lipids by one or more microalgae.

Abstract: A panel carriage hanger designed to travel slidable along a track, the panel carriage hanger having a cylindrical bore in a body, the bore having a lip substantially at a first end, the lip having a plurality of castellations. An anti-rotating sleeve having a plurality of castellations is located in the bore, and a biasing mechanism provides a substantially downwards force to the anti-rotating sleeve to mate the castellations. The anti-rotating sleeve movable substantially upwards from a first position in the bore where the castellations of the anti-rotating sleeve and the castellations of the bore mate such that the anti-rotating sleeve cannot rotate into a second position in the bore where the anti-rotating sleeve can rotate. A rod passing through and keyed to the anti-rotating sleeve such that the rod and the anti-rotating sleeve can rotate together, or both cannot rotate.

Abstract: This invention is directed in part to novel doses, dosage formulations, and routes of administration of such doses and dose formulations, said dose and dose formulations containing one or more copper chelators, for example, one or more trientine active agents, including trientine analogues, trientine salts, trientine prodrugs, and trientine derivatives, useful in the treatment of diseases, disorders and conditions, including in indications where copper may play a role.

Abstract: The disclosure relates to methods for the screening, identification, and/or application of one or more microorganisms of use in imparting one or more beneficial properties to one or more plants.

Abstract: A closure mechanism is described, the closure mechanism comprising: a base; a carriage movable along the base; a catching mechanism movable along the carriage; a first resilient mechanism connecting the base and the catching mechanism; and a second resilient mechanism connecting the carriage and the catching mechanism.

Abstract: The invention provides a novel bacterium with improved properties, including improved ethanol production, ethanol productivity, CO uptake, specific growth rate, ethanol to acetate ratio, and alcohol tolerance. The bacterium may be derived from Clostridium autoethanogenum and/or may comprise at least one DNA or amino acid sequence selected from SEQ ID NOs: 1, 3, 6, 8, 10, 12, 14, and 16. In one embodiment, the bacterium is Clostridium autoethanogenum deposited under DSMZ accession number DSM23693 or a bacterium derived therefrom.

Abstract: Described herein is an apparatus and method to convey an object through the air in a controlled and repeatable manner. The apparatus may comprise an object attached to at least one resilient member, the resilient member or members constraining object movement in a substantially vertical y-axis direction. The apparatus may also comprise at least one support member coupled to the at least one resilient member, and the support member or members constrain object movement in a substantially horizontal x-axis direction. In use, the resilient member is energised, movement initiated, and object movement then occurs in an x-axis and a y-axis direction, the movement path substantially governed by the resilient member(s) and the support member(s). The apparatus and method may allow the object to experience a variety of movement sensations, one being the feeling of flight or gliding.

Abstract: The invention relates to a method for producing products by microbial fermentation. The method comprises first converting a feed stream containing methane to a gaseous substrate comprising CO, of the invention include converting CO H2, and CO2 using a steam reforming zone and a water gas shift zone. The gaseous substrate is then converted to products such as alcohols and/or acids by to one or more products including alcohols and/or acids by fermentation using a carboxydotrophic microorganism.