Patents Assigned to New Zealand Limited
  • Dosage Forms and Related Therapies
    Publication number: 20160324804
    Abstract: This invention is directed in part to novel doses, dosage formulations, and routes of administration of such doses and dose formulations, said dose and dose formulations containing one or more copper chelators, for example, one or more trientine active agents, including trientine analogues, trientine salts, trientine prodrugs, and trientine derivatives, useful in the treatment of diseases, disorders and conditions, including in indications where copper may play a role.
    Type: Application
    Filed: July 22, 2016
    Publication date: November 10, 2016
    Applicant: PhilEra New Zealand Limited
    Inventors: Garth James Smith Cooper, John Richard Baker, Nigel Robert Arnold Beeley
  • ACCELERATED DIRECTED EVOLUTION OF MICROBIAL CONSORTIA FOR THE DEVELOPMENT OF DESIRABLE PLANT PHENOTYPIC TRAITS
    Publication number: 20160289667
    Abstract: The disclosure relates to methods for the screening, identification, and/or application of one or more microorganisms of use in imparting one or more beneficial properties to one or more plants.
    Type: Application
    Filed: June 9, 2016
    Publication date: October 6, 2016
    Applicant: BioDiscovery New Zealand Limited
    Inventors: Peter Wigley, Caroline George, Susan Turner
  • Recombinant microorganisms comprising NADPH dependent enzymes and methods of production therefor
    Patent number: 9422565
    Abstract: The invention provides a recombinant carboxydotrophic Clostridia microorganism with increased overall utilization of NADPH relative to a parent microorganism. Further, the invention provides a method of producing a recombinant carboxydotrophic Clostridia microorganism which exhibits increased NADPH utilization relative to a parental microorganism. In particular, the invention relates to increasing the overall utilization of NADPH in a recombinant carboxydotrophic Clostridia microorganism in order to increase the production of at least one fermentation product by the microorganism.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: August 23, 2016
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventors: Alexander Paul Mueller, Michael Koepke
  • Recombinant microorganisms and uses therefor
    Patent number: 9410130
    Abstract: The invention provides, inter alia, methods for the production of acetone, isopropanol and/or precursors of acetone and/or isopropanol by microbial fermentation of substrates comprising CO, genetically modified microorganisms of use in such methods, nucleic acids suitable for preparation of genetically modified microorganisms, a novel alcohol dehydrogenase and nucleic acids encoding same.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: August 9, 2016
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventors: Michael Koepke, Sean Simpson, FungMin Liew, Wendy Chen
  • Blender
    Patent number: 9393533
    Abstract: A blender including (i) a base with an interior space; (ii) a hollow central column extending upwardly from the base; (iii) a top housing mounted to the top of the column, a motor, drive transmission means and a drive shaft; (iv) an auger attached to a distal end of the drive shaft (v) a mixing bowl in coaxial alignment with the auger, (vi) a mixing bowl holder for releasably holding the mixing bowl in coaxial alignment; (vii) a ball screw drive mechanism housed within the column and for moving the mixing bowl in linear movement toward and away from the auger; and (viii) a splash guard positioned above the auger.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: July 19, 2016
    Assignee: LITTLE JEM (NEW ZEALAND) LIMITED
    Inventors: Dennis James Little, Christopher John Little
  • Fermentation process for producing isopropanol using a recombinant microorganism
    Patent number: 9365868
    Abstract: The invention provides, inter alia, methods for the production of acetone, isopropanol and/or precursors of acetone and/or isopropanol by microbial fermentation of substrates comprising CO, genetically modified microorganisms of use in such methods, nucleic acids suitable for preparation of genetically modified microorganisms, a novel alcohol dehydrogenase and nucleic acids encoding same.
    Type: Grant
    Filed: April 29, 2012
    Date of Patent: June 14, 2016
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventors: Michael Koepke, Sean Simpson, Fungmin Liew, Wendy Chen
  • Genetically engineered bacterium with altered carbon monoxide dehydrogenase (CODH) activity
    Patent number: 9365873
    Abstract: The invention provides genetically engineered microorganisms with altered carbon monoxide dehydrogenase (CODH) activity and methods related thereto. In particular, the invention provides a genetically engineered carboxydotrophic acetogenic bacterium having decreased or eliminated activity of CODH1 and/or CODH2. In certain embodiments, the bacterium may also have increased activity of CODH/ACS. The invention further provides a method for producing a product by culturing the bacterium in the presence of a gaseous substrate comprising one or more of carbon monoxide, carbon dioxide, and hydrogen.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: June 14, 2016
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventors: Michael Koepke, Fungmin Liew
  • Recombinant microorganism and methods of production thereof
    Patent number: 9359611
    Abstract: The invention relates, inter alia, to novel genetically modified microorganisms capable of using CO to produce 1-butanol and/or a precursor thereof, novel methyltransferases and nucleic acids encoding same, methods for producing genetically modified microorganisms using said novel methyltransferases, and methods of producing 1-butanol and/or a precursor thereof by microbial fermentation.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: June 7, 2016
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventors: Michael Koepke, Sean Dennis Simpson, FungMin Liew
  • Recombinant microorganisms that make biodiesel
    Patent number: 9347076
    Abstract: A carboxydotrophic acetogenic recombinant microorganism is modified so that it produces biodiesel and optionally one or more other products by fermentation of a substrate comprising CO. Biodiesel is produced by microbial fermentation of a substrate comprising CO. The recombinant microorganism is modified to express one or more exogenous enzymes in the biodiesel biosynthesis pathway not present in a parental microorganism from which the recombinant microorganism is derived. The one or more enzymes comprise a nonspecific acyltransferase.
    Type: Grant
    Filed: June 20, 2013
    Date of Patent: May 24, 2016
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventors: FungMin Liew, Michael Koepke
  • Dosage forms and related therapies
    Patent number: 9339479
    Abstract: This invention is directed in part to novel doses, dosage formulations, and routes of administration of such doses and dose formulations, said dose and dose formulations containing one or more copper chelators, for example, one or more trientine active agents, including trientine analogs, trientine salts, trientine prodrugs, and trientine derivatives, useful in the treatment of diseases, disorders and conditions, including in indications where copper may play a role.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: May 17, 2016
    Assignee: PHILERA NEW ZEALAND LIMITED
    Inventor: Garth James Smith Cooper
  • Fermentation of gaseous substrates
    Patent number: 9340802
    Abstract: Processes, as well as associated systems, are disclosed for the biological conversion of CO into desired end products such as ethanol. The use of a plurality of perforated plates, for example in the riser section of a bioreactor, which are positioned substantially horizontally and normal to the upward flow of both a CO-containing substrate and liquid culture medium, can significantly improve CO utilization of the bacteria and consequently the overall process economics. The geometry of apertures in the perforated plates is an important determinant of their performance, with fractal patterns and other multi-edged shapes leading to particularly advantageous results.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: May 17, 2016
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventor: Simon Richard Trevethick
  • ACCELERATED DIRECTED EVOLUTION OF MICROBIAL CONSORTIA FOR THE DEVELOPMENT OF DESIRABLE PLANT PHENOTYPIC TRAITS
    Publication number: 20160122750
    Abstract: The disclosure relates to methods for the screening, identification, and/or application of one or more microorganisms of use in imparting one or more beneficial properties to one or more plants.
    Type: Application
    Filed: January 8, 2016
    Publication date: May 5, 2016
    Applicant: BioDiscovery New Zealand Limited
    Inventors: Peter Wigley, Caroline George, Susan Turner
  • System and method for improved gas dissolution
    Patent number: 9327251
    Abstract: The invention provides a microbubble generation system with increased efficiency and flexibility compared to known systems. Further, the invention provides a method of microbubble generation. In particular, invention relates to increasing the efficiency of a fermentation reaction by reducing bubble size and increasing gas absorption into a liquid fermentation broth.
    Type: Grant
    Filed: January 28, 2014
    Date of Patent: May 3, 2016
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventor: Xueliang Li
  • Method of producing a recombinant microorganism
    Patent number: 9315830
    Abstract: The invention provides a genetic tool to insert, replace, delete, or otherwise manipulate a nucleic acid sequence in a microorganism to produce a recombinant microorganism. Notably, the invention makes use of homologous recombination, a type of genetic recombination in which nucleotide sequences are exchanged between two similar or identical molecules of DNA. Since the invention involves three homologous recombination events, it is referred to as a “triple cross” method.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: April 19, 2016
    Assignee: LanzaTech New Zealand Limited
    Inventors: David Jeffrey Fraser Walker, Michael Koepke
  • Lactose crystallisation
    Patent number: 9315533
    Abstract: The invention relates to a method of crystallizing lactose from a lactose-containing liquid comprising the steps of providing a lactose-containing liquid comprising less than 80% by weight total solids, providing an evaporator system that comprises a heat exchanger and an evaporation vessel, the heat exchanger comprising a tube or tubes that define a flowpath having an inlet and an outlet, heating the lactose-containing liquid in the heat exchanger to about 50 to about 90° C. such that the lactose-containing liquid passes along the flowpath by forced circulation or thermo-siphoning, concentrating the lactose-containing liquid in the evaporation vessel, to generate crystallized lactose in the lactose-containing liquid in the evaporator system.
    Type: Grant
    Filed: October 10, 2011
    Date of Patent: April 19, 2016
    Assignees: FONTERRA CO-OPERATIVE GROUP LIMITED, AUERCON NEW ZEALAND LIMITED
    Inventors: Anthony James Styles, Paul Stephenson
  • Recombinant microorganisms and methods of use thereof
    Patent number: 9297026
    Abstract: The invention relates to methods for the production of chemical compounds, particularly but not exclusively ethanol, by microbial fermentation. Also described are genetically modified micro-organisms capable of using carbon monoxide to produce one or more products, particularly but not exclusively ethanol as a main product, and producing a reduced amount or substantially no 2,3-butanediol and/or a precursor thereof.
    Type: Grant
    Filed: May 4, 2015
    Date of Patent: March 29, 2016
    Assignee: LanzaTech New Zealand Limited
    Inventors: Michael Koepke, Shilpa Nagaraju, Wendy Yiting Chen
  • Recombinant microorganisms comprising stereospecific diol dehydratase enzyme and methods related thereto
    Patent number: 9284564
    Abstract: A stereospecific enzyme in C. autoethanogenum permits the conversion of racemic propanediol to acetone and/or propionaldehyde. Entantiomeric starting materials lead to different products. If desired, the products may be reduced to form alcohols. The reaction can be performed in various host cells, so that various materials may be used as carbon and/or energy sources.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: March 15, 2016
    Assignee: LanzaTech New Zealand Limited
    Inventors: Alexander Paul Mueller, Michael Koepke
  • Therapeutic Compositions and Uses Thereof
    Publication number: 20160051594
    Abstract: The invention provides pharmaceutical compositions, including anti-gastrointestinal cancer compositions, containing propolis and cyclodextrin. Methods of using such compositions, in particular in the treatment or prevention of gastrointestinal cancers, and in the resenitisation of gastrointestinal cancers to therapy, are also provided.
    Type: Application
    Filed: April 7, 2014
    Publication date: February 25, 2016
    Applicant: Manuka Health New Zealand Limited
    Inventors: Kerry PAUL, Owen CATCHPOLE, Darina LAZAROVA
  • Accelerated directed evolution of microbial consortia for the development of desirable plant phenotypic traits
    Patent number: 9260713
    Abstract: The disclosure relates to methods for the screening, identification, and/or application of one or more microorganisms of use in imparting one or more beneficial properties to one or more plants.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: February 16, 2016
    Assignee: BIODISCOVERY NEW ZEALAND LIMITED
    Inventors: Peter Wigley, Caroline George, Susan Turner
  • GENETICALLY ENGINEERED BACTERIUM WITH ALTERED CARBON MONOXIDE DEHYDROGENASE (CODH) ACTIVITY
    Publication number: 20160040193
    Abstract: The invention provides genetically engineered microorganisms with altered carbon monoxide dehydrogenase (CODH) activity and methods related thereto. In particular, the invention provides a genetically engineered carboxydotrophic acetogenic bacterium having decreased or eliminated activity of CODH1 and/or CODH2. In certain embodiments, the bacterium may also have increased activity of CODH/ACS. The invention further provides a method for producing a product by culturing the bacterium in the presence of a gaseous substrate comprising one or more of carbon monoxide, carbon dioxide, and hydrogen.
    Type: Application
    Filed: June 29, 2015
    Publication date: February 11, 2016
    Applicant: LANZATECH NEW ZEALAND LIMITED
    Inventors: Michael Koepke, Fungmin Liew