Abstract: The object of the present invention is to provide a method for determining the sensitivity of a subject to an SGLT2 inhibitor, and a sensitivity marker for the SGLT2 inhibitor. The present invention provides a method for determining the sensitivity of a subject to an SGLT2 inhibitor, comprising measuring a biomarker in the biological sample of a subject, and determining the sensitivity of the subject to the SGLT2 inhibitor using the measured biomarker value as an indicator.

Abstract: A draw solution contains a polymeric compound produced using, as starting materials, a compound represented by general formula (a) and a compound represented by general formula (b) as a draw solute. [In formula (a) and formula (b), R1 and R2 each independently represent a hydrogen atom or a methyl group.

Abstract: A composition for absorbing carbon dioxide including an ionic liquid (A) containing a cation and an anion, and a protic compound (B) having a relative permittivity at 25° C. of 20 or more, wherein the cation at least includes a cation represented by the formula (1), the anion includes an anion where an acid dissociation constant (pKa) at 25° C. of its conjugate acid in water is 4.5 or more, and the ratio of a value obtained by multiplying the number of hydroxyl groups of the protic compound (B) by the number of moles of the protic compound (B) to the number of moles of the ionic liquid (A) [number of moles of protic compound (B)/number of moles of ionic liquid (A)] is 0.2 to 1.0: wherein R1 and R2 each independently represent a hydrogen or a C1-C6 linear alkyl group.

Abstract: A magnetized plasmoid injection device including a cylindrical external electrode, a cylindrical internal electrode coaxially disposed inside the external electrode, a plasma generating gas supply unit that supplies plasma generating gas in a pulse shape between the external electrode and the internal electrode, a magnetic field generation unit that applies a magnetic field that generates magnetized plasmoid between the external electrode and the internal electrode, a power supply control unit that applies a discharge voltage between the external electrode and the internal electrode, and an impurity generation unit that contains an impurity in the magnetized plasmoid, the impurity generation unit having a cover electrode that opens to the external electrode, a thin-rod electrode that is located inside the cover electrode and is formed of an impurity, and an impurity generation power supply that applies a voltage to the cover electrode and the thin-rod electrode.

Abstract: An object of the present invention is to provide an antifungal agent which is effective against cryptococcosis. The present invention provides an antifungal agent comprising ravuconazole as an active ingredient, wherein the agent is administered to an animal suffering from cryptococcosis. Further, the present invention provides an antifungal agent comprising ravuconazole as an active ingredient, wherein the agent is administered to an animal suffering from cryptococcus that is resistant to triazole-based antifungal agents selected from the group consisting of fluconazole, itraconazole and voriconazole.

Abstract: A panoramic X-ray imaging apparatus includes: an X-ray generating unit; an X-ray detecting unit; a support that supports the X-ray generating unit and the X-ray detecting unit; a drive mechanism that turns at least the X-ray generating unit and the X-ray detecting unit by driving the support; a displacement mechanism that adds movement including a displacement component in a direction different from the turning to the X-ray detecting unit; a subject holding unit that holds an imaging subject; a turning controller that controls the turning by a drive mechanism and the displacement mechanism. The turning controller controls the drive mechanism and the displacement mechanism so as to add the movement avoiding the contact with the shoulder of the imaging subject during the turning of the X-ray generating unit and the X-ray detecting unit by the drive mechanism during the panoramic X-ray imaging.

Abstract: The present invention is to provide a tissue slice selection method and an embedded block-preparing cassette which are capable of suppressing occurrence of errors in inspection results. The present invention makes it possible to suppress the occurrence of errors in inspection results by including: an embedded block-preparing process of preparing an embedded block by embedding both a biological tissue fragment and a standard substance in the same embedding agent; an embedded tissue slice preparing step of slicing the embedded block to prepare a sheet-like embedded tissue slice having a tissue slice and standard substance slices appearing on a surface thereof; and a tissue slice selecting step of selecting the tissue slice to be inspected, based on a light signal from the standard substance slice.

Abstract: The present invention has an object of providing a composition that is effective for the treatment of a prototheca disease. According to the present invention, a composition containing ravuconazole as an active ingredient, which is administered to an animal suffering from a prototheca disease caused by Prototheca wickerhamii or Prototheca zopfii, is provided.

Abstract: A panoramic X-ray imaging apparatus includes: an X-ray generating unit; an X-ray detecting unit; a support that supports the X-ray generating unit and the X-ray detecting unit; a drive mechanism that turns at least the X-ray generating unit and the X-ray detecting unit by driving the support; a displacement mechanism that adds movement including a displacement component in a direction different from the turning to the X-ray detecting unit; a subject holding unit that holds an imaging subject; a turning controller that controls the turning by a drive mechanism and the displacement mechanism. The turning controller controls the drive mechanism and the displacement mechanism so as to add the movement avoiding the contact with the shoulder of the imaging subject during the turning of the X-ray generating unit and the X-ray detecting unit by the drive mechanism during the panoramic X-ray imaging.

Abstract: A learning model provided in a segmentation device is a learning model which is generated using training data such that segmentation data of a biologically important region is output when data of a constituent maxillofacial region is input.

Abstract: A three-dimensional printing apparatus (1) allowing a linear filament (F) in which a fiber bundle (C) is impregnated with resin (P) to be continuously ejected includes twisting means (6) for allowing a total amount of twisting of the filament (F) or an amount of twisting of the fiber bundle (C) to be changed.

Abstract: A method of producing induced pluripotent stem cells including a step for introducing an initialization factor into somatic cells of a mammal, and culturing in a neural stem cell culture medium to obtain induced neural stem cell-like cells, and a step for cultivating said induced neural stem cell-like cells in a growth medium to obtain induced pluripotent stem cells, wherein the initialization factor contains an OCT family, a SOX family, a KLF family, a MYC family, a LIN28 family and a P53 function inhibitor.

Abstract: A nucleic acid detection kit including: (i) a first single-stranded circular DNA; (ii) a first oligonucleotide primer; (iii) a second single-stranded circular DNA; and (iv) a second oligonucleotide primer; wherein the first oligonucleotide primer is hound to a carrier through the 5?-end thereof, and the second oligonucleotide primer is bound, through the 5?-end thereof, to the carrier to which the first oligonucleotide primer is hound.

Abstract: An object of the present invention is to provide an antifungal agent which is effective against cryptococcosis. The present invention provides an antifungal agent comprising ravuconazole as an active ingredient, wherein the agent is administered to an animal suffering from cryptococcosis. Further, the present invention provides an antifungal agent comprising ravuconazole as an active ingredient, wherein the agent is administered to an animal suffering from cryptococcus that is resistant to triazole-based antifungal agents selected from the group consisting of fluconazole, itraconazole and voriconazole.

Abstract: A culture container includes: a culture container body; a partition plate disposed in the vicinity of a bottom of the culture container body to face the bottom so that a culture region is formed as a culture region between the partition plate and the bottom; and a sample inlet/outlet provided in the culture container body, the culture region and the sample inlet/outlet communicating with each other via an opening formed adjacent to one end of the partition plate. With the culture container and a culture method using this container, a large amount of adipocytes can be cultured at one time with easy handling. Dedifferentiation of a large amount of adipocytes and removal of cells having failed to dedifferentiate can be efficiently accomplished.

Abstract: A magnetized plasmoid injection device including a cylindrical external electrode, a cylindrical internal electrode coaxially disposed inside the external electrode, a plasma generating gas supply unit that supplies plasma generating gas in a pulse shape between the external electrode and the internal electrode, a magnetic field generation unit that applies a magnetic field that generates magnetized plasmoid between the external electrode and the internal electrode, a power supply control unit that applies a discharge voltage between the external electrode and the internal electrode, and an impurity generation unit that contains an impurity in the magnetized plasmoid, the impurity generation unit having a cover electrode that opens to the external electrode, a thin-rod electrode that is located inside the cover electrode and is formed of an impurity, and an impurity generation power supply that applies a voltage to the cover electrode and the thin-rod electrode.

Abstract: There is provided with a method of treating cancer. A set of administration of a compound represented by General Formula (I) or a pharmaceutically acceptable salt thereof to a patient, at a dose such that 8 mg/kg or less of the compound represented by General Formula (I) is administered, and irradiation to the patient immediately following the administration is repeated. A total dosage of the irradiation to a cancer is 10 Gy or more.

Abstract: A dental caries diagnosis device comprising a light source which is configured to emit examination light (R) and a light receiving unit (4f) which is configured to receive the examination light (R) with which a tooth has been irradiated includes: a head-side casing (4a1) which is inserted into a mouth in a contactless manner with respect to a tooth or a gum and which projects the examination light (R) toward a tooth; and a filter (4e) which is disposed in front of the light receiving unit (4f) and which is configured to remove a noise component from the received light, wherein the light receiving unit (4f) is configured to receive the examination light (R) which has been transmitted through the tooth.

Abstract: A three-dimensional printing system (1) includes: a head (2) to which a first continuous material (FL) including a resin and a second continuous material (FB) including fibers are fed; a platform (3) on which a printing material based on the first and second continuous materials from the head is stacked; a cutting device (10) which is capable of cutting at least fibers; and a controller (5) which controls an operation device including at least one of the head, the platform, and the cutting device.

Abstract: A pharmaceutical preparation efficaciously promotes tissue wound repair. The wound repair promoter according to the present invention includes at least one active ingredient selected from the group consisting of compounds represented by Formula (1), salts of the compounds, and hydrates of the compounds or the salts. In the formula, R1 and R2 are each, identically or differently, selected from hydrogen and a hydrocarbon group optionally having one or more substituents selected from the group consisting of halogens, —COOR3, —CONR32, —COR3, —CN, —NO2, —NHCOR3, —OR3, —SR3, —OCOR3, —SO3R3, and —SO2NR32, where R3 is, identically or differently in each occurrence, selected from hydrogen and an optionally substituted aliphatic hydrocarbon group; and n represents an integer of 1 or more.