Patents Assigned to Nihon University
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Patent number: 7552850Abstract: The present invention provides a clothes holding device which is easily assembled (formed) as a clothes holding device (for example, a hanger), which is compact, which has an interior function for use as an interior material. The device includes a plate member having flexibility, wherein the plate member is bent on the symmetrical axis, and clothes are held with a resulting bent portion. When clothes are not held, the clothes holding device of the present invention is assimilated with the surface of a wall, and appears to be a part of a room's interior. When holding clothes, a vertical-directional lower area of the plate member is bent along the horizontal axis, and the bent portion and the remaining portion hold clothes.Type: GrantFiled: December 8, 2003Date of Patent: June 30, 2009Assignees: Nihon University, Seems Inc.Inventors: Fujio Koeda, Kei Matsuzawa
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Patent number: 7550577Abstract: The present invention provides a polynucleotide comprising all or a part of the nucleotide sequence identified as SEQ ID NO:1 that regulates transcription of the human high-affinity IgE receptor (Fc?FI) ?-chain gene, and a method for regulating transcription of the Fc?FI ?-chain gene which comprises the step of promoting binding between a transcription regulatory complex containing MZF-1 and the transcription regulatory region of the Fc?FI ?-chain gene that contains the nucleotide sequence identified as SEQ ID NO: 1. In addition, the present invention provides a screening method and a kit therefor that utilizes the method for regulating transcription of the Fc?FI ?-chain gene having the step of promoting binding between a transcription regulatory complex containing MZF-1 and the transcription regulatory region of the Fc?FI ?-chain gene that contains the nucleotide sequence identified as SEQ ID NO:1, thereby enabling development of a novel agent for the prevention and treatment of allergic diseases.Type: GrantFiled: June 4, 2003Date of Patent: June 23, 2009Assignee: Nihon UniversityInventors: Chisei Ra, Kyoko Takahashi
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Patent number: 7537228Abstract: A monocycle, includes a wheel, a pedal, a frame portion, a saddle portion, a handle portion, and a braking unit. The wheel includes a rim having a tire, an axle arranged at a center portion of the rim, and a connecting piece for connecting the rim and the axle. The pedal can be driven to rotate the axle of the wheel. The frame portion is pivotably fixed with the axle on one end side thereof. The saddle portion is connected to the other end side of the frame portion. The handle portion is slidably and fixably connected to the other end side of the frame portion such that handle shafts of the handle portion can be slid to a position below the axle to form a stand with a bottom of the wheel. The braking unit can manually brake the wheel.Type: GrantFiled: July 22, 2003Date of Patent: May 26, 2009Assignees: Nihon University, Pixen Inc.Inventors: Toshinari Shimizu, Susumu Sasaki, Humiyoshi Suetake
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Patent number: 7534105Abstract: It is intended to provide an occludator whereby joint movements at occlusion being similar to the actual tempromandibular joint movements of an individual patient or ideal movements can be reproduced, and a face bow to be used for the occludator. To achieve this object, an occlusion plane against a standard plane is accurately drawn by using the above face bow F whereby the occlusion plane can be drawn at a high accuracy. A solid model of the tempromandibular joint similar to the tempromandibular joint form of an actual patient is used as the joint unit of the occludator K, while the positional relationship in the body at occlusion is three-dimensionally reproduced in the occludator I with the use of the above-described face bow F.Type: GrantFiled: September 26, 2003Date of Patent: May 19, 2009Assignee: Nihon UniversityInventors: Yoshinori Arai, Yutaka Akiyama, Toru Ishizuka, Hitoshi Tsunashima, Ayuta Yamada
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Patent number: 7536432Abstract: In the basic form of merge processing, that is sort processing, two sorted partial data string pairs are input, and one series of sorted data string is output as a whole. Conventionally, high parallelism of this processing has been considered difficult. A method for dividing a sorted partial data string pair into a plurality of segment pairs, if invented, would allow an advanced parallel merge processing to be performed even in a homogeneous configuration parallel computer system, such as a tightly coupled multi-processor sharing a main storage. The basis of merge processing is processing to input a pair of two sorted partial data strings and to output one sorted data string. A method for sub-dividing this input data string pair into arbitrary data string pairs from the first part of both data strings of the input data string pair, while considering the magnitude of the key value, has been invented.Type: GrantFiled: April 25, 2003Date of Patent: May 19, 2009Assignee: Nihon University School Juridical PersonInventor: Noboru Yamamoto
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Patent number: 7517655Abstract: The present invention provides the following partial fragment (a) or (b) of developmentally regulated endothelial cell locus-1 (Del-1) protein: (a) a protein consisting of the amino acid sequence as shown in SEQ ID NO: 6, 8, 10, 12, 18 or 24; or (b) a protein which consists of the amino acid sequence as shown in SEQ ID NO: 6, 8, 10, 12, 18 or 24 having deletion, substitution or addition of one or several amino acids, and has deposition activity onto extracellular matrix.Type: GrantFiled: June 30, 2004Date of Patent: April 14, 2009Assignee: Nihon UniversityInventor: Chiaki Hidai
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Publication number: 20090047685Abstract: The present invention is related to an ultrahighly sensitive determination reagent for C-reactive protein (CRP) for use in determination of CRP in a test sample with high sensitivity; and a CRP determination method using the reagent. A reagent for determining C-reactive protein containing an insoluble carrier particle loading an antibody directed to the C-reactive protein via an amino acid; and a method for determining a C-reactive protein including the steps of reacting the reagent with an antigenic substance in a test sample, and determining a resulting aggregate.Type: ApplicationFiled: June 2, 2006Publication date: February 19, 2009Applicant: Nihon UniversityInventors: Hideki Kohno, Masahiro Ogawa
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Patent number: 7462478Abstract: 2-Hydroxyisoflavanone dehydratase substantially having the amino acid sequence represented by SEQ ID NO: 1 is isolated from licorice. Further, a polynucleotide encoding 2-hydroxyisoflavanone dehydratase of the SEQ ID NO: 2 is obtained. Furthermore, the amino acid sequence of 2-hydroxyisoflavanone dehydratase is identified from soybean and a polynucleotide encoding 2-hydroxyisoflavanone dehydratase is obtained.Type: GrantFiled: March 25, 2004Date of Patent: December 9, 2008Assignee: Nihon UniversityInventors: Shin-ichi Ayabe, Tomoyoshi Akashi, Toshio Aoki
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Patent number: 7460700Abstract: An image processing method which corrects a 3-dimensional CT data value obtained from a 3-dimensional object is provided. The image processing method comprises: a threshold setting step of setting a threshold value used for generating a correction value from the 3-dimensional CT data value obtained from the 3-dimensional object; an average calculating step of calculating an average value of a 3-dimensional CT data block comprising a 3-dimensional CT data element of a correction target and a plurality of 3-dimensional CT data elements in a neighborhood of the 3-dimensional CT data element of the correction target; and a correction step of correcting the 3-dimensional CT data value by using the threshold value set in the threshold setting step and the average value obtained in the average calculating step.Type: GrantFiled: July 26, 2004Date of Patent: December 2, 2008Assignees: Nihon University, Matsumoto Dental University, J. Morita Manufacturing CorporationInventors: Hitoshi Tsunashima, Ayuta Yamada, Hozumi Kanari, Yoshinori Arai
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Patent number: 7441376Abstract: A base isolation device for a structure capable of efficiently and effectively suppressing the vibration of a structural body in surface outside direction, wherein a tension member having on overall length longer than an interval between support points provided on the structural body at a specified interval is disposed between the support points, one end parts of first link pieces are rotatably connected midway to the tension member directly or through rigid members, one end parts of second link pieces are rotatably connected to the structural body, the other end parts of the first link pieces are rotatably connected to the other end parts of the second link pieces, and an energizing member providing a tension to the tension member by energizing the first link piece and the second link piece and a damping member operated by the rotation of the first link piece and the second link piece are installed between the structural body forming the structure and connection parts between the first link pieces and the seType: GrantFiled: December 26, 2002Date of Patent: October 28, 2008Assignee: Nihon University, School Juridical PersonInventors: Shinji Ishimaru, Hidenori Ishigaki, Ippei Hata
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Publication number: 20080255368Abstract: A TGF-? gene expression inhibitor containing a pyrrole-immidazole polyamide comprising an N-methylpyrrole unit (hereinafter also referred to as Py), an N-methylimidazole unit (hereinafter also referred to as Im) and a ?-aminobutyric acid unit which can be folded into an U-shaped conformation at the above-described ?-aminobutyric acid unit site in a minor groove of a double-stranded region (hereinafter referred to as the target region) containing a part or the whole of the following base sequence (SEQ ID NO: 2) corresponding to ?450 to ?310 of human transforming growth factor ?1 (hereinafter also referred to as h TGF-?1) promoter and a strand complementary thereto and in which a Py/Im pair, an Im/Py pair and a PY/Py pair correspond respectively to a C-G base pair, a G-C base pair and an A-T base pair and a T-A base pair.Type: ApplicationFiled: August 2, 2005Publication date: October 16, 2008Applicants: Nihon University, Gentier Biosystems IncorporationInventors: Noboru Fukuda, Takahiro Ueno
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Patent number: 7431953Abstract: It is an object of the present invention to provide anti-allergic agents, skin creams, dermatitis-blocking agents, pollinosis-alleviating agents, and bath agents that serve as antipruritics derived from natural products and that prevent, alleviate and treat various itches felt on the skin. The present invention relates to anti-allergic agents, skin creams, dermatitis-blocking agents, pollinosis-alleviating agents, and bath agents comprising Purpuricenus temminckii frass as an ingredient.Type: GrantFiled: January 15, 2003Date of Patent: October 7, 2008Assignee: Nihon UniversityInventors: Seishiro Mochizuki, Hirotaka Kishida, Toshinori Ishikawa, Toshihiro Akihisa, Yoshihiro Suzuki
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Patent number: 7423405Abstract: In order to obtain an electromagnetic rotating machine of lightweight and high energy efficiency, which produces big torque for rotating a large-diameter fan, a coil A and coil B as excitation coils are disposed on an inner peripheral surface of a fan casing so as to face an outer circumference of the fan, and a coil M as an armature coil crosses at a central portion and is disposed on the outer circumference of the fan. The relationships |Iai|=|Iai+1| and Iai=?Iai+1, or |Ibi|=|Ibi+1| and Ibi=?Ibi+1 are obtained respectively for the coil A or coil B by a current control device (not shown). Moreover, the coil A and coil B are subjected to excitation control such that the direction of effective electromagnetic force, which is generated by an interaction between an effective magnetic field formed by the coil A and effective induced current applied to the coil M by the coil B, corresponds to the direction of rotation of the fan.Type: GrantFiled: January 23, 2006Date of Patent: September 9, 2008Assignees: Japan Aerospace Exploration Agency, Nihon UniversityInventors: Keiichi Okai, Takeshi Tagashira, Ryoji Yanagi, Hiroshi Nomura
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Patent number: 7416708Abstract: Efficient measuring of protein solubility with the use of a precipitating agent as crystallization parameter; and production of a high-quality protein crystal with the use of a solubility curve obtained by the measuring. Protein crystal is disposed, and the surrounding thereof is filled with a protein solution. Not only is the concentration of precipitating agent in the protein solution increased but also the interference fringes of the protein solution around the crystal are observed, and in which of dissolution, growth and equilibrium the condition of crystal resides is judged from the interference fringes. The protein concentration of protein solution is simultaneously measured, and the solubility, of protein is determined from the observation results of interference fringes together with the measured protein concentration and precipitating agent concentration. Further, a solubility curve is prepared, and a protein crystal is produced through controlling of supersaturation condition.Type: GrantFiled: October 10, 2003Date of Patent: August 26, 2008Assignee: Nihon UniversityInventor: Katsuyoshi Nakazato
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Publication number: 20080096198Abstract: It is intended to provide a primer having a promoter region added thereto; and a method of using the primer having a promoter region added thereto in RNA amplification, gene expression analysis and/or identification analysis of an organism. A primer is constructed by adding a promoter region to a random primer capable of binding to a part highly complementary to an RNA or a primer containing a base sequence complementary to a specific gene. Then, the obtained primer is employed in RNA amplification, gene expression analysis and/or identification analysis of an organism.Type: ApplicationFiled: October 14, 2005Publication date: April 24, 2008Applicant: Nihon UniversityInventors: Koichi Hiratsuka, Yoshimitsu Abiko, Michiko Kishikawa
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Patent number: 7358338Abstract: A novel heme peptide and a method for producing the same are disclosed. The invention provides a peptide with a potent NO-scavenging ability which can be used in capturing/quantifying NO and can be used as a diagnostic agent, prophylactic agent or therapeutic agent for diseases in which NO is involved, as a research reagent, as a reagent for measuring NO concentrations in the environment, and as a treating agent for removing NO in the environment.Type: GrantFiled: February 28, 2003Date of Patent: April 15, 2008Assignee: Nihon UniversityInventors: Tadatake Oku, Toshiyuki Nishio, Ryu Kawachi, Kohei Suruga
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Patent number: 7329237Abstract: To provide infusion therapy that can effectively transluminally deliver drugs or the like to a target spot without invading areas other than a diseased area. The infusion therapy is for administering a drug, cells or the like, or inserting a treatment instrument into the target diseased area. A blood vessel area including a bifurcated blood vessel connecting to the diseased area is occluded at the distal and the proximal region thereof to form an occluded area, and the drugs or the like are pumped and supplied to the occluded area, which causes the drugs or the like to flow retrogressively and retentively in the bifurcated blood vessel connecting in the occluded area, and be infused and administered to the diseased area.Type: GrantFiled: March 10, 2005Date of Patent: February 12, 2008Assignee: Nihon UniversityInventors: Shinichiro Yokoyama, Satoshi Saito, Noboru Fukuda, Daisuke Kawabe
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Patent number: 7309313Abstract: Disclosed are a vascular disease examination system capable of examining and diagnosing vascular diseases such as arterial obliteration by determining the feature quantities of blood flow velocity waveforms or blood pressure waveforms or blood flow rates, and a bypass vascular diagnosing system. A blood flow velocity or blood pressure at a target location of the body is measured A waveform analysis unit 4 determines the feature quantity of a blood flow waveform (or blood pressure waveform), for displaying on an output unit 5. The feature quantity includes a time constant, Fourier transform value, differentiated value, integrated value, rise/fall time, and sharpness or gradient of rise. Feature quantity of a blood flow velocity waveform (or blood pressure waveform) indicated in numeric value enables a correct examination/diagnosis.Type: GrantFiled: June 21, 2002Date of Patent: December 18, 2007Assignees: Nihon University, Tsukuba Technology Seed Co., Ltd.Inventors: Kin-ichi Nakata, Yoshiyuki Sankai
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Patent number: 7297405Abstract: Magnetic particles each including particulate magnetic material and a readily decomposable or easily soluble polymer coating layer containing a reactive component, the coating layer being disposed on the surface of the magnetic material; and a method for producing a reaction product by use of the magnetic particles. Employment of the magnetic particles of the present invention allows solid phase reaction to proceed efficiently and attains an easy recovery of reaction product.Type: GrantFiled: October 11, 2002Date of Patent: November 20, 2007Assignee: Nihon UniversityInventor: Hideki Kohno
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Patent number: 7281432Abstract: To be able to detect a displacement amount of a moving object by a resolution of from micrometer to nanometer by a simple structure. An excitation coil 23 and a detection coil 25 are arranged to align and a magnetic body probe 27 in a conical shape a sectional area of which is change in a longitudinal direction is arranged in a state of being inserted into an air core portion of the excitation coil 23. An output terminal from the detection coil 25 is connected to an amplifier 33 and a phase shifting circuit 35 is provided between the amplifier 33 and an input terminal of the excitation coil 23. When the probe 27 of the magnetic body is moved at inside of the air core portion of the excitation coil 23, inductance of the excitation coil 23 is changed, a phase difference is produced between an input signal inputted to the excitation coil 23 and an output signal outputted from the detection coil 25 and the phase shifting circuit 35 changes a frequency to nullify the phase difference.Type: GrantFiled: July 12, 2005Date of Patent: October 16, 2007Assignee: Nihon UniversityInventor: Sadao Omata