Abstract: An antigen membrane for syphilis diagnosis comprises cardiolipin immobilized in a polymer maxtrix. The membranes are used in syphilis diagnosis and in an apparatus for syphilis diagnosis.
Abstract: .alpha.-Cyanoamine compounds represented by the following formula or an acid addition salt thereof ##STR1## WHEREIN R.sub.1 is a halogen atom or lower alkoxy group, R.sub.2 and R.sub.3 are a hydrogen atom or lower alkoxy group, R.sub.4 is a hydrogen atom or lower alkyl group, R.sub. 5 is a hydrogen atom, --COOR.sub.6 (R.sub.6 is lower alkyl group), ##STR2## (R.sub.7 is lower alkoxy group, m is a numeral 0-3), --R.sub.8 --COOR.sub.9 (R.sub.8 is lower alkylene group, R.sub.9 is lower alkyl group), ##STR3## (R.sub.10 and R.sub.11 are a hydrogen atom or lower alkyl group, or R.sub.10 and R.sub.11 jointly form alkylene group), or ##STR4## (R.sub.1 to R.sub.4 are the same as defined above) and n is a numeral 2 or 3; but it is excluded when R.sub.5 is hydrogen atom or --COOR.sub.6 (R.sub.
Type:
Grant
Filed:
January 12, 1976
Date of Patent:
January 10, 1978
Assignees:
Fuji Chemical Industry Co., Ltd., Nippon Chemiphar Co., Ltd.
Abstract: Adamantane derivatives of this invention are represented by the formula ##STR1## wherein R.sub.1 is ##STR2## or --CH.sub.2 -- and R.sub.2 is ##STR3## or --CH.sub.2 CH=CH--. Said derivatives are cerebral vasodilators or intermediates for the same.
Abstract: .alpha.-Cyanoamine compounds represented by the following formula or an acid addition salt thereof ##SPC1##Wherein R.sub.1 is a halogen atom or lower alkoxy group, R.sub.2 and R.sub.3 are a hydrogen atom or lower alkoxy group, R.sub.4 is a hydrogen atom or lower alkyl group, R.sub.5 is a hydrogen atom, -COOR.sub.6 (R.sub.6 is lower alkyl group), ##SPC2##(R.sub.7 is lower alkoxy group, m is a numeral 0-3), --R.sub.8 --COOR.sub.9 (R.sub.8 is lower alkylene group, R.sub.9 is lower alkyl group), ##EQU1## (R.sub.10 and R.sub.11 are a hydrogen atom or lower alkyl group, or R.sub.10 and R.sub.11 jointly form alkylene group), or ##SPC3##(R.sub.1 to R.sub.4 are the same as defined above) and n is a numeral 2 or 3; but it is excluded when R.sub.5 is hydrogen atom or --COOR.sub.6 (R.sub.
Type:
Grant
Filed:
August 6, 1974
Date of Patent:
June 8, 1976
Assignees:
Fuji Chemical Industry Co., Ltd., Nippon Chemiphar Co., Ltd.
Abstract: .alpha.-Cyanobenzylpiperazines represented by the formula ##SPC1##Or an acid addition salt thereof, wherein R.sub.1 is a halogen or 1-3C lower alkoxy, R.sub.2 and R.sub.3 are each hydrogen or 1-3C lower alkoxy, R.sub.4 is 1-3C lower alkyl, and R.sub.5 is hydrogen or 1-3C lower alkyl, which are produced by reacting an aromatic carbonyl compound with hydrogen cyanide or a salt thereof and N-alkoxycarbonyl piperazine or an acid addition salt thereof.
Type:
Grant
Filed:
August 7, 1974
Date of Patent:
April 6, 1976
Assignees:
Fuji Chemical Industry Co., Ltd., Nippon Chemiphar Co., Ltd.
Abstract: Protoberberine derivatives having the general formula: ##SPC1##Wherein R.sub.1 is a lower alkoxy group, i.e. C.sub.1 to C.sub.5 alkoxy; R.sub.2 is a lower alkyl group, i.e. C.sub.1 to C.sub.5 alkyl, pyridyl group, phenyl group substituted by two or three lower alkoxy groups, i.e. C.sub.1 to C.sub.5 alkoxy or a phenylvinyl group substituted by two or three lower alkoxy groups, i.e. C.sub.1 to C.sub.5 alkoxy; having excellent analgesic, vasodilating and hypotensive effects and are prepared from know protoberberines by reaction with carobxylic acids.