Abstract: A fiber reinforced plastic (FRP) flat plate having no warps is continuously prepared by curing a continuous FRP plate molding material both top and back surfaces of which are covered with film-like sheetings by means of an ionizing radiation. In the process, the FRP molding material is continuously transported in lengthwise direction, and tensions are given to said film-like sheetings in both lengthwise and widthwise directions before and in the course of the irradiation.
Type:
Grant
Filed:
June 25, 1975
Date of Patent:
February 7, 1978
Assignees:
Nitto Boseki Co., Ltd., Japan Atomic Energy Research Institute
Abstract: A peptide having the formula:X-A-B-C-YwhereinA represents Ala., Gln., Asn., .omega.-BOC-Lys., Leu., Gly., Glu., ##EQU1## OR A represents A.sub.1 -- A.sub.2 wherein A.sub.1 represents a hydrophilic amino acid residue and A.sub.2 represents Val., Met., Leu. or Gln.;B represents Phe., Tyr., Leu., Met., Glu., Asp., Gln., Asn or Trp.;C represents Phe., Leu., Ileu., Try., Cys-SBzl., Ser-OBzl., Trp. or Met.;X represents an .alpha.-amino acid protective group; an amino acid residue having an N-terminal protective group or a peptide residue having an N-terminal protective group; Y represents a carboxyl protective group, an amino acid residue having a C-terminal protective group or a peptide residue having a C-terminal group, is produced in a process which comprises reacting a peptide having the formulaX-A-B-OHwith an amino acid or a peptide having the formulaH-C-Yin the presence of enzyme pepsin.
Type:
Grant
Filed:
April 29, 1975
Date of Patent:
August 3, 1976
Assignees:
Sagami Chemical Research Center, Nitto Boseki Co., Ltd.
Abstract: Pyrimidine derivatives represented by the formula, ##SPC1##Wherein R.sub.1 and R.sub.2 are individually a hydrogen atom or a methyl group, and R.sub.3 is a group formed by removing the carboxyl group from a carboxylic acid, are quite useful in acylating compounds having amino and/or imino and/or hydroxyl groups. The pyrimidine derivatives can easily be prepared by reacting a 2-mercapto-4- and/or 6-methyl-substituted or unsubstituted pyrimidine with a carboxylic acid or a reactive derivative thereof in an inert solvent.
Abstract: Thiolcarbonates represented by the formula, ##SPC1##Wherein R.sub.1 and R.sub.2 are individually a hydrogen atom or a methyl group, and R.sub.3 is a straight chain or branched chain saturated or unsaturated alkyl group having 1 to 5 carbon atoms or is a benzyl or benzhydryl group which may be nuclear substituted, are easily produced by reacting an alkali metal salt of 2-mercaptopyrimidine with phosgene, and reacting the resulting thiolchloroformate with an alcohol (R.sub.3 OH).
Abstract: Thiolcarbonates represented by the formula, ##SPC1##Wherein R.sub.1 and R.sub.2 are individually a hydrogen atom or a methyl group, and R.sub.3 is a straight chain or branched chain saturated or unsaturated alkyl group having 1 to 5 carbon atoms or is a benzyl or benzhydryl group which may be nuclear substituted, are quite useful for protecting the amino or imino groups of amines, hydrazines, amino acids and peptides with groups of the formula ##EQU1## The thiolcarbonates can be easily produced by reacting an alkali metal salt of 2-mercaptopyrimidine with phosgene, and reacting the resulting thiolchloroformate with an alcohol (R.sub.3 OH), or by reacting a 2-mercaptopyrimidine with a halocarbonic acid ester.