Patents Assigned to Northeastern University
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Patent number: 8713948Abstract: A drilling system including a motor that produces a sonic, linear oscillatory motion is provided for removing a frozen biological sample from a stored frozen specimen and methods of use thereof without thawing the remainder of the specimen. The stator and slider assembly is operated by a servo controller which can communicate and be programmed through a port of a PC equipped with software.Type: GrantFiled: May 23, 2013Date of Patent: May 6, 2014Assignees: President and Fellows of Harvard College, Northeastern UniversityInventors: Dale Larson, Jeffrey Ruberti, John Slusarz, Trevor Ehret, Nicholas Goulas, Erin Rush
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Patent number: 8719936Abstract: An intrusion detection system collects architectural level events from a Virtual Machine Monitor where the collected events represent operation of a corresponding Virtual Machine. The events are consolidated into features that are compared with features from a known normal operating system. If an amount of any differences between the collected features and the normal features exceeds a threshold value, a compromised Virtual Machine may be indicated. The comparison thresholds are determined by training on normal and abnormal systems and analyzing the collected events with machine learning algorithms to arrive at a model of normal operation.Type: GrantFiled: February 2, 2009Date of Patent: May 6, 2014Assignee: Northeastern UniversityInventors: Micha Moffie, David Kaeli, Aviram Cohen, Javed Aslam, Malak Alshawabkeh, Jennifer Dy, Fatemeh Azmandian
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Patent number: 8703501Abstract: The present invention provides a method for directed assembly of a conducting polymer. A method of the invention comprises providing a template such as an insulated template and electrophorectically assembling a conducting polymer thereon. Preferably, the template comprises a patterned electrode on which the conducting polymer is assembled. Moreover, the invention provides a method for transferring an assembled conducting polymer. For example, a method of the invention comprises providing a substrate such as a polymeric substrate and contacting a surface thereof with an assembled conducting polymer. The assembled conducting polymer can be disposed on a patterned electrode of a template, hi one embodiment, a method comprises removing the substrate. By removing the substrate, the assembled conducting polymer is transferred from the patterned electrode of the template to the substrate. The invention also provides a device with a template or substrate comprising an assembled conducting polymer.Type: GrantFiled: June 7, 2006Date of Patent: April 22, 2014Assignee: Northeastern UniversityInventors: Joey L. Mead, Carol M. F. Barry, Ahmed Busnaina, Ming Wei, Zhenghong Tao
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Patent number: 8691088Abstract: A method of preparing an ultra-nanoscale-LC monolithic separation medium for use in capillary columns, or channels in microfabricated devices (microchips), and capillaries prepared by the method are disclosed. The application of moderate positive pressure to both ends of the capillary during the monolith polymerization process permits the preparation of monolithic capillary columns having very low i.d., e.g., 25 ?m and smaller, with enhanced mass transfer properties and low back pressures, and excellent column-to-column reproducibility of retention times.Type: GrantFiled: April 21, 2006Date of Patent: April 8, 2014Assignee: Northeastern UniversityInventors: Alexander R. Ivanov, Li Zang, Barry L. Karger
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Patent number: 8685538Abstract: Stable nanoparticles comprising poorly soluble drugs are disclosed, as well as methods of making and methods of using such nanoparticles, e.g., as therapeutics and diagnostics.Type: GrantFiled: March 25, 2010Date of Patent: April 1, 2014Assignees: Northeastern University, Louisiana Tech University Research Foundation, a Division of Louisiana Tech University Foundation, Inc.Inventors: Vladimir Torchilin, Yuri Lvov, Zhiguo Zheng
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Publication number: 20140085693Abstract: A birefringent reflectarray having a planar metasurface containing metallic patches of subwavelength dimension is provided. The reflectarray is capable of simultaneously reflecting, concentrating, and splitting incident infrared light into two orthogonal linearly polarized reflections, and transforms the phase front of an incoming polarized light to a desired phase for the two reflections. Also provided is an optical modulator having a metasurface containing layers of nanoantennas of subwavelength dimension, and capable of modulating the phase and amplitude of light scattered from the modulator. The optical modulator has ability to perform computation through processing of light.Type: ApplicationFiled: September 26, 2013Publication date: March 27, 2014Applicant: Northeastern UniversityInventors: Hossein Mosallaei, Mohsen Farmahini Farahani, Babak Memarzadeh Isfahani
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Publication number: 20140070111Abstract: In some aspects, the disclosure is directed to signal processing methods and systems for identifying a material on a body of a person using electromagnetic radiation. A radar system may measure a first reflection of radiation incident on a body of a person. The first reflection may be from a surface of the body. The radar system may measure a second reflection of the radiation. The second reflection may be from a first material residing on or proximate to the surface of the body. An analyzer may determine, relative to the first reflection, a delay in the second reflection due to propagation of a portion of the radiation through the first material. The analyzer may determine, based on the delay, at least one of: the first material and a dielectric constant of the first material.Type: ApplicationFiled: August 16, 2013Publication date: March 13, 2014Applicant: Northeastern UniversityInventors: Carey Rappaport, Jose Angel Martinez-Lorenzo
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Patent number: 8668978Abstract: Nanosubstrates as biosensors, methods of making such nanosubstrates, and methods of using such nanosubstrates to detect biomarkers are described.Type: GrantFiled: September 2, 2010Date of Patent: March 11, 2014Assignee: Northeastern UniversityInventors: Asanterabi Malima, Ahmed Busnaina, Salome Siavoshi, Sivasubramanian Somu, Cihan Yilmaz, Tiziana Musacchio, Jaydev Upponi, Vladimir Torchilin
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Patent number: 8661891Abstract: An apparatus for measuring the liquid level of molten metal including an image measuring device (5), a measuring probe (6), a lifting mechanism (1), a displacement sensor (11), an data processing system (4) and a correction marker(7). The lifting mechanism (1) is fixed to the molten metal container (10) or is independent of the molten metal container, the image measuring device (5) and the measuring probe (6) are installed on the lifting mechanism (1) or are independent of the lifting mechanism, and the optical axis of the image measuring device (5) is set at an angle with the geometric axis of the measuring probe (6), the measuring probe (6) is located within the field of view of the image measuring device (5), the image measuring device (5), the lifting mechanism (1) and the displacement sensor (11) are connected to the data processing system (4) respectively. A method for measuring the level of molten metal is also disclosed.Type: GrantFiled: October 28, 2008Date of Patent: March 4, 2014Assignees: Northeastern University, Shenyang Taihe Metallurgy Measurement & Control Technology Co., Ltd.Inventors: Zhi Xie, Zhenwei Hu, Ying Ci, Da Zhang
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Publication number: 20140055314Abstract: In some aspects, the disclosure is directed methods and systems for focusing millimeter-wave radiation to a line for scanning a target object. A source may provide millimeter-wave radiation, and may include a substantially point source. A reflector may include a surface with an elliptical cross-section within a first plane and a curved cross-section within a second plane perpendicular to the first plane. The curved cross-section may be shaped differently from the elliptical cross-section within their respective planes. The surface may focus the millimeter-wave radiation from the source at a line on a third plane parallel to or coinciding with the second plane. The line may be located at an approximate location where a target object is expected to be positioned. At least one sensor may measure the millimeter-wave radiation from the reflector scattered off the target object.Type: ApplicationFiled: August 20, 2013Publication date: February 27, 2014Applicant: Northeastern UniversityInventor: Carey Rappaport
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Publication number: 20140033804Abstract: A polymer-based PLOT capillary column prepared by in situ copolymerization of a functional monomer and a crosslinking monomer, which enhances the strength of the polymer matrix, is disclosed. Also disclosed is a system comprising the polymer-based PLOT column coupled to a mass flow or concentration sensitive detector, for carrying out a chemical analysis method on samples separated by liquid chromatography using the column, and a process for using the system. Columns of the invention can be prepared in a robust fashion with a very narrow i.d., e.g., 5-15 ?m. Thus, they are suitable for commercial use in ultratrace LC/MS proteomic analysis. Columns according to the invention are characterized by high resolving power and high column-to-column reproducibility. When these columns are coupled on-line with, e.g., ESI-MS detection, the resulting systems are capable of detecting the component parts of complex proteomic samples down to the low attomole to sub-attomole level.Type: ApplicationFiled: October 8, 2013Publication date: February 6, 2014Applicant: Northeastern UniversityInventors: Barry L. Karger, Jian Zhang
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Patent number: 8637356Abstract: A non-volatile bistable nano-electromechanical switch is provided for use in memory devices and microprocessors. The switch employs carbon nanotubes as the actuation element. A method has been developed for fabricating nanoswitches having one single-walled carbon nanotube as the actuator. The actuation of two different states can be achieved using the same low voltage for each state.Type: GrantFiled: June 27, 2012Date of Patent: January 28, 2014Assignee: Northeastern UniversityInventors: Sivasubramanian Somu, Ahmed Busnaina, Nicol McGruer, Peter Ryan, George G. Adams, Xugang Xiong, Taehoon Kim
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Patent number: 8631091Abstract: In one embodiment, program code is added to a social network's web pages or site such that the content a first user accesses is locally stored at the first user's system. When another user, who is a friend of the first user, as defined by the social networking site, browses to that same content, the program code fetches it from the first user, instead of directly from the social networking site. The content is thus directly exchanged between the users without a transaction at the website. The present invention leverages the storage and bandwidth resources of social networking users to help serve content.Type: GrantFiled: October 17, 2011Date of Patent: January 14, 2014Assignee: Northeastern UniversityInventors: Alan Mislove, Ravi Sundaram
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Patent number: 8628912Abstract: Methods of identifying subjects having, or at risk of developing, diabetes, obesity, and/or hypertension are disclosed, as well as methods of identifying biomarkers for diabetes, obesity, and/or hypertension, and biomarkers identified by such methods.Type: GrantFiled: July 3, 2008Date of Patent: January 14, 2014Assignee: Northeastern UniversityInventors: William S. Hancock, Marina Hincapie, M. K. Disni R. Dayarathna
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Publication number: 20130333399Abstract: A drilling system including a motor that produces a sonic, linear oscillatory motion is provided for removing a frozen biological sample from a stored frozen specimen and methods of use thereof without thawing the remainder of the specimen. The stator and slider assembly is operated by a servo controller which can communicate and be programmed through a port of a PC equipped with software.Type: ApplicationFiled: May 23, 2013Publication date: December 19, 2013Applicants: Northeastern University, President and Fellows of Harvard CollegeInventors: Dale Larson, Jeffrey Ruberti, John Slusarz, Nicholas Goulas, Erin Rush, Trevor Ehret
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Publication number: 20130330747Abstract: Nanosubstrates as biosensors, methods of making such nanosubstrates, and methods of using such nanosubstrates to detect biomarkers are described.Type: ApplicationFiled: March 15, 2013Publication date: December 12, 2013Applicant: Northeastern UniversityInventor: Northeastern University
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Patent number: 8589684Abstract: A communication device, method and network are provided. The communication method comprises generating a first registration packet including first bio data, sending the first registration packet to a network, generating a content packet having second bio data and content data and sending the content packet to the network. The other communication method comprises receiving a first registration packet including first bio data, storing the first bio data together with a device identification, receiving a content packet including second bio data, extracting the second bio data from the content packet, comparing the first bio data with the second bio data and authorizing communication when the first bio data matches the second bio data.Type: GrantFiled: March 18, 2010Date of Patent: November 19, 2013Assignee: Northeastern University Technology Transfer CenterInventor: Zhenhua Tan
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Patent number: 8580570Abstract: A polymer-based PLOT capillary column prepared by in situ copolymerization of a functional monomer, which usually contains the retentive chemistries, and a crosslinking monomer, which enhances the strength of the polymer matrix, is disclosed. Also disclosed is a system comprising the polymer-based PLOT column coupled to a mass flow or concentration sensitive detector, for carrying out a chemical analysis method on samples separated by liquid chromatography using the column, and a process for using the system. Columns of the invention can be prepared in a robust fashion with a very narrow i.d., e.g., 5-15 ?m. Thus, they are suitable for commercial use in ultratrace LC/MS proteomic analysis. Columns according to the invention are characterized by high resolving power and high column-to-column reproducibility. When these columns are coupled on-line with, e.g.Type: GrantFiled: July 15, 2011Date of Patent: November 12, 2013Assignee: Northeastern UniversityInventors: Barry L. Karger, Jian Zhang
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Patent number: 8521714Abstract: Technologies are generally described for a peer to peer search routing algorithm and system. In one example, a node in a peer to peer network includes a processor. In some examples, the processor may be configured to receive information regarding a topology of the peer to peer network and generate a first search routing algorithm for the peer to peer network based on the topology. In some examples, the processor may be configured to generate a second search routing algorithm for the peer to peer network based on a search characteristic and the topology. In some examples, the second search routing algorithm is distinct from the first search routing algorithm. In some examples, the processor may be configured to receive a request to search the peer to peer network. In some examples, the processor may be configured to search the peer to peer network using the second search routing algorithm.Type: GrantFiled: August 25, 2010Date of Patent: August 27, 2013Assignee: Northeastern University Technology Transfer CenterInventor: Zhenhua Tan
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Publication number: 20130209991Abstract: Sensors based on single-walled carbon nanotubes (SWNT) are integrated into a microfluidic system outfitted with data processing and wireless transmission capability. The sensors combine the sensitivity, specificity, and miniature size of SWNT-based nanosensors with the flexible fluid handling power of microfluidic “lab on a chip” analytical systems. Methods of integrating the SWNT-based sensor into a microfluidic system are compatible with the delicate nature of the SWNT sensor elements. The sensor devices are capable of continuously and autonomously monitoring and analyzing liquid samples in remote locations, and are applicable to real time water quality monitoring and monitoring of fluids in living systems and environments. The sensor devices and fabrication methods of the invention constitute a platform technology, because the devices can be designed to specifically detect a large number of distinct chemical agents based on the functionalization of the SWNT.Type: ApplicationFiled: January 10, 2013Publication date: August 15, 2013Applicant: Northeastern UniversityInventor: Northeastern University