Patents Assigned to Northeastern University
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Patent number: 8494676Abstract: A robotic architecture for capturing the autonomous performance advantages the animal models enjoy in the natural environment is disclosed. A biomimesis process is employed to allow selective utilization of basic physical components and adaptation of a common control paradigm for each of different vehicle types. The biomimetic architecture involves five functional elements: a basic biomorphic plant for capturing the biomechanical advantages of the model organism; a neural circuit-based controller consisting of a finite state machine; myomorphic actuators producing linear graded force in response to trains of current pulses for mediating movements; labeled line code output by neuromorphic sensors; and a reactive behavioral sequencer executing command sequences defined within a behavioral library.Type: GrantFiled: June 22, 2010Date of Patent: July 23, 2013Assignee: Northeastern UniversityInventors: Joseph Ayers, Jan Witting, Stephane Ryder, Christopher Olcott
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Patent number: 8449427Abstract: A sequential planetary stack transmission system is provided. The system includes a stack of planetary gear sets, each gear set including a sun gear engageable with a rotatable central shaft, and freely rotatable concentrically about the central input or output shaft when not engaged with the central shaft. A plurality of planet gears engage with the sun gear, and a ring gear engages with the planet gears. The ring gears form a ring gear barrel rotatable as a unit concentrically with respect to the central shaft. A shifting assembly within the hollow central shaft engages sequentially with the sun gears to provide a desired gear ratio. The planetary stack assembly and the shifting assembly are disposed within a case. The system is suitable for a variety of applications, and is particularly suitable for bicycles.Type: GrantFiled: December 3, 2008Date of Patent: May 28, 2013Assignee: Northeastern UniversityInventors: Michael Witonis, Jay Seiter, Morgan Misek, Joshua Filgate, Jesse Kuhn
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Patent number: 8452371Abstract: Techniques for imaging a blood vessel are described. A transducer attached to a catheter is guided to a first site within a blood vessel. The catheter is moved to a second site proximal to the first site at a speed selected to enable the transducer to generate a signal indicative of a geometry wall, the lumen, and a portion of the side branch. A first image of the blood vessel obtained from the signal is oriented with a second image of the blood vessel such that a first portion of the first image aligns with a second portion of the second image.Type: GrantFiled: March 1, 2007Date of Patent: May 28, 2013Assignees: The Brigham and Women's Hospital, Inc., Northeastern UniversityInventors: Charles L. Feldman, Peter Stone, Ahmet U. Coskun
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Patent number: 8448456Abstract: A drilling system including a motor that produces a sonic, linear oscillatory motion is provided for removing a frozen biological sample from a stored frozen specimen and methods of use thereof without thawing the remainder of the specimen. The stator and slider assembly is operated by a servo controller which can communicate and be programmed through a port of a PC equipped with software.Type: GrantFiled: January 16, 2007Date of Patent: May 28, 2013Assignees: President and Fellows of Harvard College, Northeastern UniversityInventors: Dale Larson, Jeffrey Ruberti, John Slusarz, Nicholas Goulas, Erin Rush, Trevor Ehret
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Patent number: 8450674Abstract: A light microscope for imaging a sample containing one or more fluorescent agents, comprising a source for generating acoustic waves that are focused at a focus in the sample, wherein the acoustic waves frequency shift a frequency of light passing through the focus, thereby creating a frequency shifted light beam; at least one spatial light modulator (SLM) positioned to illuminate the sample with an output beam that is an optical phase conjugate of the frequency shifted light beam, wherein the output beam is a reflection of a first reference beam off one or more pixels of the SLM, and the pixels are for modulating the first reference beam to create the output beam; and a detector positioned to detect fluorescence generated by the output beam exciting the fluorescent agents at the focus in the sample, thereby imaging the sample.Type: GrantFiled: November 10, 2010Date of Patent: May 28, 2013Assignees: California Institute of Technology, Northeastern UniversityInventors: Changhuei Yang, Charles DiMarzio, Meng Cui, Ying Min Wang
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Patent number: 8438513Abstract: A new method is presented for eliminating existential quantifiers from a Boolean CNF (Conjunctive Normal Form) formula. This new method designs circuits by solving a quantifier elimination problem (QEP) by using derivation of dependency sequents (DDS). This new method begins with a first quantified conjunctive normal form formula, determines dependency sequents for the left branch and the right branch of a branching variable, resolves dependency sequents derived in both branches, and designs a circuit using a current formula having less variables than the first quantified conjunctive normal formula. Utility of this method includes verification, in particular, determining reachability of a state of a design.Type: GrantFiled: December 30, 2011Date of Patent: May 7, 2013Assignee: Northeastern UniversityInventors: Evgueni I. Goldberg, Panagiotis Manolios
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Publication number: 20130110422Abstract: A fault detector for operating process of electric arc furnace and method thereof are disclosed, which belong to the technical field of fault detection. The fault detector includes the temperature signal acquisition equipment, the current signal acquisition equipment and a host computer. The multimode fault monitoring and diagnosis method comprises the following steps: acquiring and standardizing the data; establishing the preliminary monitoring model for the operating process to obtain common subsets of M operating modes and typical subsets of every operating mode; calculating the T2 statistics and the SPE statistics, and monitoring and diagnosing fault in the operating process. The present invention has the advantages that the colorimetric temperature measurement can improve the calculation accuracy, different equipment becomes compatible, and the fault detector is suitable for operating in industrial production process with a variety of steady modes and can diagnose faults in a certain operating mode.Type: ApplicationFiled: January 31, 2011Publication date: May 2, 2013Applicant: Northeastern UniversityInventors: Yingwei Zhang, Wenyou Du, Zhiming Li, Yunpeng Fan
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Patent number: 8428320Abstract: Embodiments of the present disclosure provides improved methods for determining the presence of abnormalities in exfoliated cells. In one embodiment, the present disclosure provides methods for reconstructing cellular spectrum of a cell sample by creating a spectral map of the cellular sample, generating a binary mask of the spectral map, removing edge artifacts from each cell, and co-adding spectral data of each pixel corresponding to the cell to reconstruct the spectrum of each cell.Type: GrantFiled: May 29, 2009Date of Patent: April 23, 2013Assignee: Northeastern UniversityInventors: Max Diem, Milos Miljkovic, Melissa Romeo, Benjamin Bird, Jennifer Schubert, Kostas Papamarkakis
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Patent number: 8428331Abstract: A method and device are provided for counting cells in a sample of living tissue, such as an embryo. The method involves obtaining a microscopic image of the unstained tissue that reveals cell boundaries, such as a differential interference contrast (DIC) image, and an optical quadrature microscopy (OQM) image which is used to prepare an image of optical path length deviation (OPD) across the cell cluster. The boundaries of individual cells in the cell cluster are modeled as ellipses and used, together with the maximum optical path length deviation of a cell, to calculate ellipsoidal model cells that are subtracted from the OPD image. The process is repeated until the OPD image is depleted of phase signal attributable to cells of the cell cluster, and the cell count is obtained from the number of cells subtracted.Type: GrantFiled: August 7, 2007Date of Patent: April 23, 2013Assignee: Northeastern UniversityInventors: Charles A. DiMarzio, William C. Warger, II
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Patent number: 8395552Abstract: A broadband integrated circulator antenna (BICA) module for receiving and transmitting signals with high efficiency and high gain. The BICA can have a bandwidth of over 70% of a radar band and can operate in frequencies from UHF to S-band and above. The BICA has a stack configuration that includes a low profile antenna, a reflecting layer or a metamaterial substrate layer, and a circulator. The circulator is placed proximal to antenna, which greatly reduces the size of the BICA. The circulator can be a stripline Y-junction ferrite circulator and the antenna can be a coaxial center fed bow-tie antenna. The reflecting layer or metamaterial substrate layer can comprise electronic bandgap metamaterial and a high permeability ferrite substrate. The high permeability ferrite substrate can be cobalt substituted Z-type barium hexaferrite.Type: GrantFiled: November 21, 2011Date of Patent: March 12, 2013Assignees: Metamagnetics, Inc., Northeastern UniversityInventors: Anton L. Geiler, Carmine Vittoria, Vincent G. Harris
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Patent number: 8362618Abstract: An assembly of nanoelements forms a three-dimensional nanoscale circuit interconnect for use in microelectronic devices. A process for producing the circuit interconnect includes using dielectrophoresis by applying an electrical field across a gap between vertically displaced non-coplanar microelectrodes in the presence of a liquid suspension of nanoelements such as nanoparticles or single-walled carbon nanotubes to form a nanoelement bridge connecting the microelectrodes. The assembly process can be carried out at room temperature, is compatible with conventional semiconductor fabrication, and has a high yield. The current-voltage curves obtained from the nanoelement bridge demonstrate that the assembly is functional with a resistance of ?40 ohms for gold nanoparticles. The method is suitable for making high density three-dimensional circuit interconnects, vertically integrated nanosensors, and for in-line testing of manufactured conductive nanoelements.Type: GrantFiled: November 8, 2007Date of Patent: January 29, 2013Assignee: Northeastern UniversityInventors: Ahmed Busnaina, Mehmet R. Dokmeci, Nishant Khanduja, Selvapraba Selvarasah, Xugang Xiong, Prashanth Makaram, Chia-Ling Chen
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Patent number: 8338570Abstract: Methods and compositions are described for organizing collagen into fibrillar networks, e.g, short and long-range organization. Collagen produced by the disclosed methods can be used for tissue engineering.Type: GrantFiled: October 8, 2010Date of Patent: December 25, 2012Assignee: Northeastern UniversityInventors: Nima Saeidi, Jeffrey W. Ruberti
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Publication number: 20120323136Abstract: Electrical impedance myography (EIM) can be used for the assessment and diagnosis of muscular disorders. EIM includes applying an electrical signal to a region of tissue and measuring a resulting signal. A characteristic of the region of tissue is determined based on the measurement. Performing EIM at different frequencies and/or different angular orientations with respect to a muscle can aid in the assessment and diagnosis. Devices are described that facilitate assessment and diagnosis using EIM.Type: ApplicationFiled: August 29, 2012Publication date: December 20, 2012Applicants: Beth Israel Deaconess Medical Center, Inc., Northeastern UniversityInventors: Carl A. Shiffman, Ronald Aaron, Seward B. Rutkove
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Publication number: 20120302653Abstract: Disclosed herein are gel and plastic compositions comprising tightened layers of polymerized vinyl monomers, as well as methods of making the same, where the layers are tightened in having smaller pores. The tightened layers comprise tightened inner layers and exterior layers, and the compositions comprise polymer-attached (pendant) initiator or helper residues.Type: ApplicationFiled: September 9, 2010Publication date: November 29, 2012Applicant: Northeastern UniversityInventors: Roger W. Giese, Gang Shao
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Publication number: 20120264224Abstract: Systems and methods are disclosed herein for a microfluidic calorimeter apparatus. A microfluidic calorimeter system includes a calorimetry apparatus and a processor in connection with the apparatus. The apparatus includes a microfluidic laminar flow channel connected to two inlets for flowing fluid into the laminar flow channel. Below the laminar flow channel is a plurality of microscale temperature sensors at known positions in the channel. The processor is in connection with the discrete temperature sensors and determines a calorimetry measurement based on local temperatures derived from data output by the microscale temperature sensors and the respective positions of the sensors in the channel.Type: ApplicationFiled: January 13, 2012Publication date: October 18, 2012Applicants: Northeastern University, The Charles Stark Draper Laboratory, Inc.Inventors: Jason O. Fiering, Dale Larson, Gregory Kowalski, Mehmet Sen
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Publication number: 20120219489Abstract: Methods and apparatus to generate carbon nanostructures from organic materials are described. Certain embodiments provide solid waste materials into a furnace, that pyrolyzes the solid waste materials into gaseous decomposition products, which are then converted to carbon nanostructures. Methods and apparatuses described herein provide numerous advantages over conventional methods, such as cost savings, reducion of handling risks, optimization of process conditions, and the like.Type: ApplicationFiled: March 26, 2010Publication date: August 30, 2012Applicant: Northeastern UniversityInventors: Yiannis Levendis, Henning Richter, Chuanwei Zhuo
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Patent number: 8231070Abstract: A device and method to provide a simplified wash process and controlled disintegration of a soft substance, such as a gel, are disclosed. In use, a block of, e.g., gel matrix is placed in the device and washed with a series of appropriate solutions to remove interfering contaminants. The washing liquid is removed through a deformable narrow opening in the bottom of the device, and, subsequently, the gel block is extruded through the deformable narrow opening, by a physical force, such as centrifugal force, a vacuum or positive pressure from a gas or liquid, etc., resulting in fragmentation of the gel block into a series of particles of similar size. The fragmentation of the gel results from shear forces exerted onto the gel block traveling through the deformable narrow opening in the device.Type: GrantFiled: May 29, 2007Date of Patent: July 31, 2012Assignee: Northeastern UniversityInventors: Alexander Lazarev, Thomas Rejtar, Barry L. Karger
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Patent number: 8225677Abstract: A capacitive sensor for measuring flow parameters of a two-phase flow, a device for measuring phase concentration of a two-phase flow, and a system and method for measuring flow parameters of a two-phase flow is disclosed. In the capacitive sensor, at least one pair of electrodes is twisted by 180° in a common direction into a spiral shape. Edge guard electrodes are twisted in the common direction and are formed between adjacent electrode edges. Problems of non-homogeneous sensitivity distribution of a measuring field and soft field effect can be effectively addressed, thereby allowing reliable and accurate measurement of phase concentration of a two-phase flow. The system for measuring flow parameters of the two-phase flow can output signals with a current of 4˜20 mA to a PLC system or communicate with an industrial process control computer or with a remote control computer system in a operating room.Type: GrantFiled: November 6, 2009Date of Patent: July 24, 2012Assignee: Northeastern UniversityInventors: Yutao Wang, Gang Yang, Zengxi Lu
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Publication number: 20120172339Abstract: Novel resorcinol derivatives and methods of preparation and use are presented. These compounds can stimulate angiogenesis as a biological function triggered by the activation of one cannabinoid receptor distinct from CB1 and CB2. Thus, these compounds are specific ligands for one cannabinoid receptor distinct from CB1 and CB2. The invented compounds, when administered in a therapeutically effective amount to an individual or animal, results in a sufficiently high level of that compound in the individual or animal to cause a physiological response. The physiological response may be useful to treat a number of physiological conditions.Type: ApplicationFiled: July 9, 2010Publication date: July 5, 2012Applicant: Northeastern UniversityInventors: Alexandros Makriyannis, Spyridon P. Nikas, Shariku O. Alapafuja
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Patent number: 8211765Abstract: A non-volatile bistable nano-electromechanical switch is provided for use in memory devices and microprocessors. The switch employs carbon nanotubes as the actuation element. A method has been developed for fabricating nanoswitches having one single-walled carbon nanotube as the actuator. The actuation of two different states can be achieved using the same low voltage for each state.Type: GrantFiled: September 9, 2011Date of Patent: July 3, 2012Assignee: Northeastern UniversityInventors: Sivasubramanian Somu, Ahmed Busnaina, Nicol McGruer, Peter Ryan, George G. Adams, Xugang Xiong, Taehoon Kim