Patents Assigned to Novo Industri A/S
  • Immobilization of biologically active material with glutaraldehyde and polyazetidine
    Patent number: 4892825
    Abstract: Immobilized biologically active material in particle form is prepared by cross-linking with glutaraldehyde and polyazetidine. An aqueous dispersion or solution of biologically active material is partially cross-linked with glutaraldehyde, a wet pasty mass is recovered by dewatering and the mass is sub-divided into discrete particles. A polyazetidine prepolymer is added before, at the beginning or subsequent to partially cross-linking but prior to subdividing the pasty mass into particles, and the prepolymer is allowed to cross-link.
    Type: Grant
    Filed: June 30, 1988
    Date of Patent: January 9, 1990
    Assignee: Novo Industri A/S
    Inventors: Mogens Wumpelmann, Henrik Mollgaard
  • Process for the liquefaction of beets and chicory roots by enzymatic hydrolysis and liquid hydrolysate obtained
    Patent number: 4886672
    Abstract: A process for the liquifaction of beets or chicory roots which includes washing and grinding the beets or chicory roots to provide a ground product; mixing the ground product with a mixture of enzymes that include SPS-ase, cellulase and cellobiase, as well as an acid so as to provide a pH of about 3 to 5.5; leaving the mixture for about 1 to 6 hours to accomplish a prehydrolysis of the ground product; grinding the prehydrolyzed ground product; allowing the prehydrolyzed ground product to hydrolyze for about 20 to 120 hours; and recovering the liquid hydrolyzed product.
    Type: Grant
    Filed: March 2, 1988
    Date of Patent: December 12, 1989
    Assignees: Sucre Recherches et Developpement, Novo Industri A/S
    Inventors: Regis J. M. P. de Baynast de Septfontaines, Francois E. M. E. Brouard, Jean-Luc A. G. Baret, Yvon G. A. J. M. Gicquiaux, Hans S. Olsen
  • Enzymatic detergent additive, a detergent, and a washing method
    Patent number: 4876024
    Abstract: A lipolytic enzymatic detergent additive, the lipase of which is from a lipase producing strain of Pseudomonas cepacia, detergent compositions containing such an additive and washing with the detergent compositions at temperatures below about 60.degree. C.
    Type: Grant
    Filed: August 6, 1986
    Date of Patent: October 24, 1989
    Assignee: Novo Industri A/S
    Inventors: Michiyo Enomoto, Steen Riisgaard
  • Method for production of an enzyme granulate
    Patent number: 4876198
    Abstract: An enzyme granulation process wherein an enzyme solution or suspension, filler, binder and cellulose or artificial fibres are granulated with fines and oversize particles of the granulate product particle the process being characterized by recirculation of fines without grinding, by grinding oversize particles then recirculation thereof, with the recirculated particles as a whole exhibiting a cumulative size distribution of the same general shape as the cumulative size distribution of the granulate product particles.
    Type: Grant
    Filed: August 19, 1988
    Date of Patent: October 24, 1989
    Assignee: Novo Industri A/S
    Inventor: Erik K. Markussen
  • Dietetic foodstuff containing low calorie bulking agent
    Patent number: 4871571
    Abstract: A bulking agent which can replace sucrose and other soluble simple carbohydrates in food, the active component of which is a glucose oligomer or a mixture of glucose oligomers, DP=3, or 4, wherein each oligomer exhibits one beta-1,3-glucosidic bond, all other bonds being beta-1,4-glucosidic bonds. The bulking agent has a satisfactory taste and a satisfactory stability at low pH values. The bulking agent can be produced by hydrolysis of .beta.-glucan.
    Type: Grant
    Filed: June 30, 1987
    Date of Patent: October 3, 1989
    Assignee: Novo Industri A/S
    Inventors: Villy J. Jensen, Sven Pedersen, Hans A. S. Olsen
  • Enzymatic method for preparation of epoxy compounds
    Patent number: 4859589
    Abstract: An epoxy group in a molecule can enzymatically be transferred to another molecule, thereby synthesizing carbohydrates carrying an epoxy group in the aglycone position.
    Type: Grant
    Filed: November 17, 1987
    Date of Patent: August 22, 1989
    Assignee: Novo Industri A/S
    Inventors: Sven E. Godtfredsen, Fredrik Bjorkling
  • Process for preparing glucagon or fragments or derivatives thereof in yeast
    Patent number: 4826763
    Abstract: Glucagon or fragments or derivatives thereof are prepared by cultivation of a yeat strain transformed with a replicable expression vehicle comprising a gene encoding the expression of such products. Synthetic genes encoding glucagon or derivatives thereof have been constructed. Also provided are replicable expression vehicles comprising a replication system for providing stable maintenance in yeast and a DNA-sequence encoding glucagon or fragments or derivatives thereof and transformant yeast strains containing such expression vehicles.
    Type: Grant
    Filed: January 21, 1986
    Date of Patent: May 2, 1989
    Assignee: Novo Industri A/S
    Inventors: Kjeld Norris, Lars Thim, Fanny Norris, Mogens T. Hansen, Alister J. Moody
  • Enzymatic synthesis of waxes
    Patent number: 4826767
    Abstract: Process for generating an about 98% ester yield from fatty acids and fatty alcohols comprising esterifying the acid and alcohol in liquid phase under a vacuum of at least 0.5 bar in the presence of an immobilized lipase.
    Type: Grant
    Filed: October 31, 1986
    Date of Patent: May 2, 1989
    Assignee: Novo Industri A/S
    Inventor: Tomas T. Hansen
  • Immobilized Mucor miehe lipase for transesterification
    Patent number: 4818695
    Abstract: Immobilized lipase is produced by mixing an aqueous lipase solution with a particulate, macroporous, weak anion exchange resin, and recovering and drying the resin having lipase immobilized thereon. The resin has a particle size such that more than 90% resin particles have a size between 100-1000 .mu.m. The immobilized lipase is used in a packed bed for continuous transesterification or solvent free fats. Preferably, the lipase is Mucor miehei lipase.
    Type: Grant
    Filed: July 31, 1987
    Date of Patent: April 4, 1989
    Assignee: Novo Industri A/S
    Inventor: Peter Eigtved
  • Peptides and compositions
    Patent number: 4816441
    Abstract: Peptides of the formula R.sup.1 -His-Asp-Glu-Ala-R wherein R.sup.1 is Ala-Gln, and R is a polypeptide residue with up to 50 amino acid residues, and wherein one, more or all of the amino acid residues in R.sup.1 and/or R independently may be omitted, can be used to augment cell mediated cytotoxicity and thereby to treat cancers and viral infections. These peptides may be prepared by proteolytic digestion of Staphylococcus aureus protein A, as well as by protein synthesis, recombinant DNA methods or any other methods known in the art.
    Type: Grant
    Filed: November 14, 1986
    Date of Patent: March 28, 1989
    Assignee: Novo Industri A/S
    Inventors: Jesper Zeuthen, Lars Thim, Niels P. H. Moller
  • Enzymatic detergent additive
    Patent number: 4810414
    Abstract: Lipase is derived from Humicola sp. (incl. Theremomyces sp.), preferably H. lanuginosa. This lipase is found to have high activity at alkaline pH and to be compatible with anionic surfactants, and it is more effective as a detergent additive than previously described detergent lipases.
    Type: Grant
    Filed: August 28, 1987
    Date of Patent: March 7, 1989
    Assignee: Novo Industri A/S
    Inventors: Ida B. Huge-Jensen, Erik Gormsen
  • Immobilized Mucor miehei lipase for transesterification
    Patent number: 4798793
    Abstract: Immobilized lipase is produced by mixing an aqueous lipase solution with a particulate, macroporous, phenolformaldehyde adsorbent resin, and recovering and drying the resin having lipase immobilized thereon. The resin has a particle size such that more than 90% resin particles have a size between 100-1000 .mu.m. The immobilized lipase is used in a packed bed for continuous transesterfication of solvent free fats. Preferably, the lipase is Mucor miehei lipase. The immobilized lipase has on a dry basis at least 10 batch interesterification units (BIU) and at least 500 lipase units (LU).
    Type: Grant
    Filed: July 31, 1987
    Date of Patent: January 17, 1989
    Assignee: Novo Industri A/S
    Inventor: Peter Eigtved
  • Pet food
    Patent number: 4784860
    Abstract: A pet food containing a proteinaceous vegetable source component treated with an SPS-ase preparation in aqueous medium. Presence of this component imparts a decisive improvement in regard to the elasticity and palatability of the pet food.
    Type: Grant
    Filed: October 22, 1986
    Date of Patent: November 15, 1988
    Assignee: Novo Industri A/S
    Inventors: Flemming M. Christensen, Hans A. S. Olsen, Columbus O. L. Boyce
  • Herbicide
    Patent number: 4753670
    Abstract: Disease causing material obtained by cultivation of Phomopsis cirsii or Septoria cirsii can be used for controlling weeds such as compositae.
    Type: Grant
    Filed: September 6, 1984
    Date of Patent: June 28, 1988
    Assignee: Novo Industri A/S
    Inventor: Vibeke Leth
  • 2,3,4,5-tetrahydro-1H-3-benzazepines and CNS affecting use thereof
    Patent number: 4751222
    Abstract: Novel 2,3,4,5-tetrahydro-1H-3-benzazepines which in the 5-position have furyl, thienyl, pyridyl, or ring systems consisting of phenyl ortho condensed with a benzen, cyclohexan, cyclohexen, cyclopentan or cyclopenten ring wherein one of the carbon atoms may be exchanged with oxygen, sulphur or nitrogen, have interesting central nervous system and cardiovascular effects.
    Type: Grant
    Filed: April 21, 1986
    Date of Patent: June 14, 1988
    Assignee: Novo Industri A/S
    Inventors: Claus Braestrup, Peter H. Andersen, Poul Borrevang, Frederik C. Gr nvald, Louis B. Hansen, Rolf Hohlweg
  • Clarification agent for colored cellulose fabrics and method for treatment of such fabrics
    Patent number: 4738682
    Abstract: Treatment of colored cellulose fiber fabrics for at least fifteen minutes with an aqueous solution of cellulase containing at least about 250 CMC units per liter under pH conditions conducive to high activity for the cellulase clarifies the color.
    Type: Grant
    Filed: October 2, 1986
    Date of Patent: April 19, 1988
    Assignee: Novo Industri A/S
    Inventors: Kirsten Boegh, Soren J. Jepsen
  • Xylose isomerase (glucose isomerase) from Streptomyces murinus cluster
    Patent number: 4687742
    Abstract: Xylose isomerase, from strains of the Streptomyces murinus cluster, a method for production of such xylose isomerase, immobilized xylose isomerase and a method for isomerization of glucose to fructose therewith.
    Type: Grant
    Filed: March 25, 1985
    Date of Patent: August 18, 1987
    Assignee: Novo Industri A/S
    Inventors: Georg Skoet, Hanne Guertler
  • Method for production of a low alcoholic wine
    Patent number: 4675191
    Abstract: Generating a low alcohol content wine by oxidizing the glucose content in unfermented grape juice to gluconic acid through treatment of the juice with glucose oxidase in the presence of oxygen followed by fermentation.The process may be carried out to adjust the acidity of the wine, in which only a small proportion of the glucose is oxidized.
    Type: Grant
    Filed: February 7, 1986
    Date of Patent: June 23, 1987
    Assignee: Novo Industri A/S
    Inventor: Jean-Claude Villettaz
  • Method for production of an immobilized enzyme preparation by means of a crosslinking agent
    Patent number: 4665028
    Abstract: A method for production of an immobilized enzyme by means of a crosslinking agent wherein the following components are brought together in aqueous medium:(a) an enzyme preparation;(b) a crosslinking agent; and(c) an inert water soluble salt in a relatively high concentration.The salt hinders solubility of the enzyme in the medium, yet the enzyme is fully accessible to the crosslinking agent. High enzyme activity recovery may be obtained.
    Type: Grant
    Filed: October 5, 1983
    Date of Patent: May 12, 1987
    Assignee: Novo Industri A/S
    Inventor: Shmuel Amotz
  • Applicator for inserting a suppositorium or the like
    Patent number: D289691
    Type: Grant
    Filed: September 28, 1984
    Date of Patent: May 5, 1987
    Assignee: Novo Industri A/S
    Inventor: Jorn Rex