Patents Assigned to Novozyme A/S
  • PROTEASE VARIANTS WITH IMPROVED SOLUBILITY
    Publication number: 20230265408
    Abstract: The present invention relates to protease variants, polynucleotides encoding said variants, nucleic acid constructs and expression vectors comprising said polynucleotides, host cells expressing said variants, methods of obtaining the variants, detergent compositions comprising said variants, and use of said variants or said detergent compositions.
    Type: Application
    Filed: August 30, 2021
    Publication date: August 24, 2023
    Applicant: Novozymes A/S
    Inventors: Rolf Thomas Lenhard, Esben Peter Friis, Poul Erik Pedersen, Rasmus Lund Andersen
  • DNase variants
    Patent number: 11732252
    Abstract: The present invention relates to polypeptide variants and methods for obtaining variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: November 19, 2021
    Date of Patent: August 22, 2023
    Assignee: Novozymes A/S
    Inventors: Lars Henrik Oestergaard, Gernot J. Abel, Dorte Marie Koefoed Klitgaard, Annette Helle Johansen
  • Polypeptides having mannanase activity and polynucleotides encoding same
    Patent number: 11732221
    Abstract: The present invention relates to polypeptides having mannanase activity, catalytic domains, and carbohydrate binding modules, and polynucleotides encoding the polypeptides, catalytic domains, and carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains, and carbohydrate binding modules.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: August 22, 2023
    Assignee: Novozymes A/S
    Inventors: Tine Hoff, Markus Klinger
  • Lipase variants and polynucleotides encoding same
    Patent number: 11725197
    Abstract: The present invention relates to a variant of a parent lipase, wherein said variant has at least 60% but less than 100% sequence identity with SEQ ID NO: 2; has lipase activity; has substitutions corresponding to G91A and N92D in the lid region located from position G82 to position 1100 of SEQ ID NO: 2; has one or more additional substitutions in the lid region; and has at least mutations in positions corresponding to position T231 and position N233 of SEQ ID NO: 2. The present invention also relates to compositions, methods for cleaning a surface using a variant or a composition of the invention; polynucleotides encoding the variants; nucleic acid constructs, vectors, host cells comprising the polynucleotides; methods of using the variants; and methods for obtaining the lipase variant.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: August 15, 2023
    Assignee: Novozymes A/S
    Inventors: Allan Svendsen, Sune Fang Christensen, Lars Lehman Hylling Christensen, Vikram Kjoller Bhatia, Jesper Vind, Vibeke Skovsgaard Nielsen
  • Method for screening alpha-amylases
    Patent number: 11718840
    Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: August 8, 2023
    Assignee: NOVOZYMES A/S
    Inventors: Svend Kaasgaard, Signe Eskildsen Larsen, Jens Oebro, Lars Beier, Connie Pontoppidan, Iben Damager, Carsten Andersen, Allan Svendsen
  • MUTANTS OF A FILAMENTOUS FUNGAL CELL HAVING INCREASED PRODUCTIVITY IN THE PRODUCTION OF A POLYPEPTIDE
    Publication number: 20230242960
    Abstract: The present invention relates to a mutant of a parent filamentous fungal cell, comprising: a polynucleotide encoding a polypeptide of interest; a racA gene encoding a Rho-GTPase RacA protein, wherein the racA gene is modified rendering the mutant partially or completely deficient in the production of the Rho-GTPase RacA protein; and a ras2 gene encoding a GTPase Ras2 protein, wherein the GTPase Ras2 protein is modified to produce a GTPase Ras2 variant comprising a substitution at a position corresponding to position 16 of SEQ ID NO: 11, wherein the combination of the modified racA gene and the Ras2 variant synergistically increases the productivity of the mutant in the production of the polypeptide of interest. The present invention also relates to a method of producing a polypeptide of interest with such a mutant.
    Type: Application
    Filed: January 12, 2021
    Publication date: August 3, 2023
    Applicant: Novozymes A/S
    Inventor: Gloria Erichsen
  • PROCESS FOR PRODUCING ETHANOL FROM RAW STARCH USING ALPHA-AMYLASE VARIANTS
    Publication number: 20230235367
    Abstract: The present invention relates to raw starch hydrolysis and in particular to a raw starch hydrolysis and fermentation process.
    Type: Application
    Filed: February 9, 2021
    Publication date: July 27, 2023
    Applicant: Novozymes A/S
    Inventors: Carsten Andersen, Thomas Agersten Poulsen, Dorota Nissen, Marie Thryøse Kruse, Sarah Schultheis Elliott, Shiro Fukuyama
  • MILLING PROCESS
    Publication number: 20230235094
    Abstract: The present invention provides process for treating crop kernels, comprising the steps of a) soaking kernels in water to produce soaked kernels; b) grinding the soaked kernels; c) treating the soaked kernels in the presence of an effective amount of GH62 polypeptide having arabinofuranosidase activity or a GH43 polypeptide having arabinofuranosidase activity, wherein step c) is performed before, during or after step b).
    Type: Application
    Filed: April 12, 2023
    Publication date: July 27, 2023
    Applicant: NOVOZYMES A/S
    Inventors: James Lavigne, Bernardo Vidal, JR., Thomas Patrick Gibbons, Chee-Leong Soong, Randall Scott Deinhammer, Zhen Long, Yi Cao, Michael John Akerman, Xinyu Shen, Yu Zhang, Brian R. Scott
  • STERILE FILTERED LACTASE PREPARATION COMPRISING SALT WITH MONOVALENT CATION
    Publication number: 20230225345
    Abstract: The present invention relates to a sterile-filtered liquid lactase preparation and to a method of sterile filtering a liquid lactase preparation.
    Type: Application
    Filed: January 6, 2023
    Publication date: July 20, 2023
    Applicant: Novozymes A/S
    Inventors: Cedric Hobel, Karen Jensen
  • IMPROVED FIBER-WASHING IN CORN WET-MILLING
    Publication number: 20230227585
    Abstract: A method for increasing starch yield and/or gluten yield from corn kernels in a wet milling process, comprising contacting a fiber rich fraction of ground kernels, with an effective amount of SO2, and an effective amount of one or more hydrolytic enzymes, wherein at least one of said hydrolytic enzymes is selected from xylanase and/or cellulase enzymes, during a fiber-washing step.
    Type: Application
    Filed: July 7, 2021
    Publication date: July 20, 2023
    Applicant: Novozymes A/S
    Inventors: Bernardo Vidal, Jr., Yi Cao, Oscar Pastor Ferrer, Brian Manning, Madelyn Mallison Shoup, Svend Gunnar Kaasgaard, Mary Ann Stringer, Lorena Gonzalez Palmen
  • METHOD FOR IMPROVING OIL YIELD FROM GERM IN A WET MILLING PROCESS
    Publication number: 20230220296
    Abstract: The present invention provides a method for improving oil yield from germ in a wet milling process, the method comprising admixing a process stream comprising corn germ with an enzyme composition comprising an effective amount of one or more hydrolytic enzymes, wherein at least one of said hydrolytic enzymes is a xylanase polypeptide selected from the group consisting of: GH5, GH10, GH30, GH11 polypeptides.
    Type: Application
    Filed: July 1, 2021
    Publication date: July 13, 2023
    Applicant: Novozymes A/S
    Inventor: Thomas Patrick Gibbons
  • Microbial Cleaning Compositions
    Publication number: 20230220307
    Abstract: The invention provides an aqueous microbial cleaning composition having excellent storage and germination properties, comprising bacterial spores and alkyl polyglucosides or sodium lauryl ether sulfates.
    Type: Application
    Filed: June 1, 2021
    Publication date: July 13, 2023
    Applicant: Novozymes A/S
    Inventors: Kenneth Edmund Kellar, Hilary Cheeseman, John Harp
  • Polypeptide Variants
    Publication number: 20230220366
    Abstract: The present invention relates to novel lactase variants having improved properties relative to the parent lactase, such as decreased galactose inhibition or increased galactose inhibition. The variants of the invention are suitable for production of dairy products, such as low-lactose dairy products or lactose-free dairy products. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the lactase variants of the invention.
    Type: Application
    Filed: February 23, 2021
    Publication date: July 13, 2023
    Applicant: Novozymes A/S
    Inventors: Roland Alexander Pache, Anders Gunnar Sandstrom, Jan Kjoelhede Vester, Henrik Friis-Madsen, Dorota Nissen
  • SUBTILASE VARIANTS AND COMPOSITIONS COMPRISING SAME
    Publication number: 20230212548
    Abstract: The invention relates to subtilase variants, compositions comprising the variants, and methods of using the variants and compositions, e.g. for laundry or hard surface cleaning such as dishwashing.
    Type: Application
    Filed: May 26, 2021
    Publication date: July 6, 2023
    Applicant: Novozymes A/S
    Inventors: Esben Peter Friis, Rolf Thomas Lenhard, Lars Lehmann Hylling Christensen, Julie Bille Rannes
  • METHOD FOR CONTROLLING SLIME IN A PULP OR PAPER MAKING PROCESS
    Publication number: 20230212822
    Abstract: The present invention pertains to the field of pulp or paper making. More specifically the present invention relates to a method of preventing a build-up of slime or removing slime from a surface contacted with water from a pulp or paper making process. The present invention can control slime in an efficient and environmentally friendly way.
    Type: Application
    Filed: May 28, 2021
    Publication date: July 6, 2023
    Applicant: Novozymes A/S
    Inventors: Pedro Emanuel Garcia Loureiro, Anne Marie Scharff-Poulsen, Kasper Bay Tingsted
  • Polypeptides having trehalase activity and the use thereof in process of producing fermentation products
    Patent number: 11685910
    Abstract: The present invention relates to polypeptides having trehalase activity. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using a trehalase of the invention, in particular a process of producing a fermentation product, such as ethanol.
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: June 27, 2023
    Assignee: NOVOZYMES A/S
    Inventors: Zhengfang Kang, Kirk Matthew Schnorr, Lar Kobberøe Skov
  • ENGINEERED MICROORGANISM FOR IMPROVED PENTOSE FERMENTATION
    Publication number: 20230193216
    Abstract: Described herein are recombinant host organisms having an active pentose fermentation pathway and further comprising a heterologous polynucleotide encoding a non-phosphorylating NADP-dependent glyceraldehyde-3-phosphate dehydrogenase (GAPN). Also described are processes for producing a fermentation product, such as ethanol, from starch or cellulosic-containing material with the recombinant host organisms.
    Type: Application
    Filed: May 12, 2021
    Publication date: June 22, 2023
    Applicant: Novozymes A/S
    Inventors: Monica Tassone, Eric Allain
  • PROTEASE ANIMAL FEED FORMULATION
    Publication number: 20230189844
    Abstract: The reformulation of RONOZYME® ProAct protease polypeptide to a more economical microgranulate, extrudate, high-shear granulate or spray drying formulation each provide good thermostability and suitability for use as an animal feed additive.
    Type: Application
    Filed: December 8, 2022
    Publication date: June 22, 2023
    Applicant: Novozymes A/S
    Inventor: Flemming Borup
  • Method for Producing a Dairy Product
    Publication number: 20230189830
    Abstract: The present invention relates to a method for producing a dairy product using an enzyme having lactase activity.
    Type: Application
    Filed: October 13, 2022
    Publication date: June 22, 2023
    Applicant: Novozymes A/S
    Inventors: Hanne Vang Hendriksen, Steffen Ernst, Reinhard Wilting, Jeppe Wegener Tams, Mette Oerhrstroem Runge, Helle Skov Guldager
  • LOW DUSTING GRANULES
    Publication number: 20230193162
    Abstract: The invention provides a method for preparing a plurality of granules comprising a biological active and a non-volatile liquid by using mixer-granulation, wherein the granules exhibit reduced dust release upon exposure to mechanical stress.
    Type: Application
    Filed: October 15, 2018
    Publication date: June 22, 2023
    Applicant: Novozymes A/S
    Inventors: Ole Simonsen, Poul Bach, Albert Cervera-Padrell, Lars Jensen, Lei Shang, Lotte Elisabeth Nissen