Abstract: Described herein are recombinant host organisms having an active pentose fermentation pathway and further comprising a heterologous polynucleotide encoding a non-phosphorylating NADP-dependent glyceraldehyde-3-phosphate dehydrogenase (GAPN). Also described are processes for producing a fermentation product, such as ethanol, from starch or cellulosic-containing material with the recombinant host organisms.
Abstract: The reformulation of RONOZYME® ProAct protease polypeptide to a more economical microgranulate, extrudate, high-shear granulate or spray drying formulation each provide good thermostability and suitability for use as an animal feed additive.
Abstract: The invention provides a method for preparing a plurality of granules comprising a biological active and a non-volatile liquid by using mixer-granulation, wherein the granules exhibit reduced dust release upon exposure to mechanical stress.
Type:
Application
Filed:
October 15, 2018
Publication date:
June 22, 2023
Applicant:
Novozymes A/S
Inventors:
Ole Simonsen, Poul Bach, Albert Cervera-Padrell, Lars Jensen, Lei Shang, Lotte Elisabeth Nissen
Abstract: The present invention relates to serine protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease derived from a strain of Meripilus giganteus belonging to the S53 family. The varinats according to the invention have in particular increased stability, e.g., increased thermo-stability, increased specific activity, and/or increased expression levels, compared to the parent protease. The present invention also relates to polynucleotides encoding the variants; nucleic N acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Type:
Application
Filed:
July 14, 2017
Publication date:
June 22, 2023
Applicant:
NOVOZYMES A/S
Inventors:
Dorte M.K. Klitgaard, Roland Alexander Pache, Martin Gudman, Anders G. Sandström
Abstract: The present invention relates to polypeptides having hexosaminidase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
Type:
Grant
Filed:
March 11, 2020
Date of Patent:
June 20, 2023
Assignee:
NOVOZYMES A/S
Inventors:
Christian Berg Oehlenschlaeger, Dorotea Raventos Segura, Rebecca Munk Vejborg, Henrik Marcus Geertz-Hansen, Lilian Eva Tang Baltsen, Jesper Salomon
Abstract: The present invention relates to processes for separating wheat flour into two or more fractions including a gluten fraction and a starch fraction, comprising the steps of: a) mixing wheat flour and water; b) adding one or more polypeptide (s) having GH8 xylanase activity; c) incubating the mixture for a predefined period of time; d) separating the mixture into two or more fractions including a gluten rich fraction and a starch rich fraction; and e) recovering the two or more fractions including a gluten rich fraction and a starch rich fraction.
Type:
Application
Filed:
December 20, 2018
Publication date:
June 15, 2023
Applicant:
Novozymes A/S
Inventors:
James Lavigne, Gernot Abel, Jesper Salomon, Tucker Shepperd
Abstract: The present invention relates to xylanase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; compositions comprising the xylanase variants and methods of using the variants.
Type:
Application
Filed:
October 25, 2022
Publication date:
June 15, 2023
Applicant:
Novozymes A/S
Inventors:
Annette Helle Johansen, Steffen Danielsen, Frank Winther Rasmussen, Peter Kamp Hansen, Roland Alexander Pache
Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants and to nucleic acid constructs, vectors, and host cells comprising the polynucleotides, and methods of using the variant enzymes.
Type:
Application
Filed:
February 6, 2023
Publication date:
June 15, 2023
Applicants:
Novozymes A/S, Novozymes North America, Inc.
Inventors:
carsten Andersen, Randall Deinhammer, Thomas Agersten Poulsen, Miguel Duarte Toscano, Peter Kamp Hansen, Henrik Friis-Madsen, Anders Viksoe-Nielsen, Signe Eskildsen Larsen, Lars L.H. Christensen
Abstract: The present invention relates to protease variants and methods for obtaining protease variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Type:
Application
Filed:
November 3, 2022
Publication date:
June 15, 2023
Applicant:
Novozymes A/S
Inventors:
Jens Erik Nielsen, Pernille Hede, Esben Peter Friis
Abstract: Described herein are recombinant host organisms having an active arabinose fermentation pathway and further comprising a heterologous polynucleotide a heterologous polynucleotide encoding a L-xylulose reductase (LXR). Also described are processes for 5 producing a fermentation product, such as ethanol, from starch or cellulosic-containing material with the recombinant host organisms.
Abstract: A process of recovering oil, comprising (a) converting a starch-containing material into dextrins with an alpha-amylase; (b) saccharifying the dextrins using a carbohydrate source generating enzyme to form a sugar; (c) fermenting the sugar in a fermentation medium into a fermentation product using a fermenting organism; (d) recovering the fermentation product to form a whole stillage; (e) separating the whole stillage into thin stillage and wet cake; (e?) optionally concentrating the thin stillage into syrup; (f) recovering oil from the thin stillage and/or optionally the syrup, wherein a protease and a phospholipase are present and/or added during steps (a) to (c). Use of a protease and a phospholipase for increasing oil recovery yields from thin stillage and/or syrup in a fermentation product production process.
Type:
Grant
Filed:
May 3, 2021
Date of Patent:
June 13, 2023
Assignee:
NOVOZYMES A/S
Inventors:
Joseph Jump, Nathaniel Edward Kreel, Bernardo Vidal, Jr., Chee-Leong Soong, Madison Roberts, Melissa Carrie Hooss, Xinyu Shen
Abstract: The present invention relates to fungal host cells comprising nucleic acid constructs comprising a heterologous promoter operably linked to polynucleotidea encoding a chaperone, nucleic acid constructs comprising a polynucleotide encoding a chaperone, and methods for producing polypeptides of interest.
Type:
Grant
Filed:
March 25, 2019
Date of Patent:
June 6, 2023
Assignee:
Novozymes A/S
Inventors:
Jean-Marie Mouillon, Pernille Hvid Christensen
Abstract: The present invention relates to a method of making glucose syrup from liquefied starch comprising, (a) contacting the liquefied starch with a glucoamylase, a pullulanase, and optionally an alpha-amylase wherein the ratio of pullulanase dose expressed as NPUN/gDS, to alpha-amylase dose expressed as FAU(A)/gDS is at least 60, particularly at least 75, particularly at least 100, more particularly at least 150, more particularly at least 200, more particularly at least 250, more particularly at least 300, more particularly at least 400, more particularly at least 500, more particularly at least 600, more particularly at least 800 or if no alpha-amylase is present the pullulanse is present in a dose of at least 0.5, particularly at least 0.75, particularly at least 1.0, particularly at least 1.5 NPUN/gDS, and (b) saccharifying the liquefied starch.
Abstract: Disclosed is a method for controlling the carbon feed to a fed-batch fermenter based on the disturbance of the pH signal following the addition or a limiting substrate.
Abstract: The invention relates to cleaning compositions comprising a fructan degrading enzyme and at least one cleaning component, and use of such compositions for cleaning of an item such as a textile or a surface.
Type:
Application
Filed:
April 20, 2021
Publication date:
June 1, 2023
Applicant:
Novozymes A/S
Inventors:
Marc Dominique Morant, Lorena Gonzalez Palmen, Klaus Gori, Jesper Salomon
Abstract: Disclosed are variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.
Type:
Grant
Filed:
April 12, 2019
Date of Patent:
May 30, 2023
Assignee:
Novozymes A/S
Inventors:
Svend Gunnar Kaasgaard, Frank Winther Rasmussen, Roland Alexander Pache, Lars Anderson, Mette Louise Dissing Overgaard, Thomas Agersten Poulsen, Lars Giger
Abstract: The present invention relates to compositions such as cleaning compositions comprising a mix of enzymes. The invention further relates to use of compositions comprising such enzymes in cleaning processes.
Type:
Application
Filed:
January 19, 2021
Publication date:
May 25, 2023
Applicant:
Novozymes A/S
Inventors:
Iben Damager, Lise Munch Mikkelsen, Henrik Lund
Abstract: The present invention relates to xylanase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; compositions comprising the xylanase variants and methods of using the variants.
Type:
Application
Filed:
November 3, 2022
Publication date:
May 25, 2023
Applicant:
Novozymes A/S
Inventors:
Annette Helle Johansen, Steffen Danielsen, Frank Winther Rasmussen, Peter Kamp Hansen, Roland Alexander Pache
Abstract: The present invention deals with a method for improving the rollability of flat breads comprising a) adding a maltogenic alpha-amylase and a beta amylase to a flour or directly to a dough comprising a flour; b) making the dough; and c) making flat breads from the dough.