Abstract: One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include an X-ray applicator for emitting an X-ray beam for irradiating an object. The mobile X-ray unit may further include a phantom-based dosimetry system configured to perform a dosimetry check of the X-ray beam. The phantom-based dosimetry system may include two sets of dose meters, each set being positioned on a surface at a distinct depth. The mobile X-ray unit may also include a dosimetry control unit configured to receive measurements from the two sets of dose meters and determine whether the dosimetry check is passed based on the measurements.

Abstract: Embodiments of the disclosure are drawn to methods of forming an applicator body of an applicator for insertion into an anatomical cavity of a patient for delivering a treatment to the patient. In some instances, the method may include receiving a first three-dimensional image of the anatomical cavity, which was generated while the anatomical cavity contained an expandable container adjacent a tissue region of the patient, and while the expandable container was filled with fluid such that the container was expanded to substantially conform to the shape of at least a portion of the tissue region. The method also may include isolating, from the first three-dimensional image, a first sub-image corresponding to an image of the filled expanded container. The method further may include using the first sub-image as a design template for forming the applicator body for use with the patient.

Abstract: One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base accommodating a control unit for controlling an X-ray applicator and a power supply for supplying power to the X-ray applicator. The mobile X-ray unit may further include an arm associated with the base. The arm may be configured to support an X-ray applicator having an X-ray tube. The arm may be articuable. The X-ray tube may include a target element configured to generate an X-ray beam and a collimator configured to shape the X-ray beam. The target element may be disposed at a set distance from the collimator.

Abstract: The invention relates to a real time radiation treatment planning system for use in effecting radiation therapy of a pre-selected anatomical portion of an animal body using hollow needles. According to embodiments of the invention, the system may include a processing means processing means-configured to perform a three-dimensional imaging algorithm and a three-dimensional image segmentation algorithm, with respect to one or more specific organs within the pre-selected anatomical portion and with respect to the needles, for converting the image data obtained with an imaging means into a three-dimensional image of the anatomical portion, using at least one single or multi-objective anatomy-based genetic optimization algorithm.

Abstract: An embodiment of the present disclosure is directed to a radioactive source tracking system adapted to determine in real time a spatial position of a gamma source in a volume, including a set of spatially distributed position sensitive detectors operable in real time arranged about the volume. The system includes a real time computer system adapted to calculate the spatial position per time stamp of the gamma source in the volume based on respective signals generated by the position sensitive detectors. In addition, the radioactive source is represented by a 3D or 4D data stream in real time. Other embodiments of the present disclosure are directed to a method for tracking a radioactive gamma source and a computer program product for causing a processor to determine a real time 3D or a 4D spatial position of a gamma source.

Abstract: The invention relates to a method for identifying the location at least one treatment channel from a group of a plurality of treatment channels as wells as a system for effecting radiation treatment on a pre-selected anatomical portion of an animal body. According to the invention the identifying method being characterized by the steps of A selecting at least one of said plurality of treatment channels; B reconstructing the actual location of said selected treatment channel relative to said animal body; and C comparing said reconstructed location said pre-planned plurality of locations. Furthermore the system according to the invention is characterized in that identifying means are present for identifying the location of at least one treatment channel from said group of said plurality of inserted treatment channels and comparing said identified location with one or more of said pre-planned locations present in said treatment plan.

Abstract: One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base and an arm associated with the base. The arm may be configured to support an X-ray applicator having an X-ray tube. The X-ray tube may be configured to generate an X-ray beam. The X-ray applicator may include an exit surface through which the X-ray beam passes in use. The X-ray unit may further include an applicator cap for covering at least the exit surface of the X-ray applicator.

Abstract: The invention relates to a brachytherapy instrument comprising a body, wherein the body is provided with at least one marker comprising a material suitable to be visualized using an ultrasonic and/or magnetic resonance imaging technique. The invention further relates to an image acquisition system and a method of image acquisition.

Abstract: The invention relates to a brachytherapy applicator device for insertion in a body cavity. The applicator device comprises an applicator shaped for insertion in the body cavity; the applicator comprising connectable segments; at least one connectable part having a form following wall surface shaped to follow the body cavity, the wall surface having a multichannel groove structure, so as to guide a plurality of catheters along the grooves in the groove structure along the wall surface.

Abstract: One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base for accommodating a control unit for controlling an X-ray applicator and a power supply for supplying power to the X-ray applicator. The mobile X-ray unit may further include an articulated arm associated with the base and coupled to the X-ray applicator. The X-ray applicator may have an X-ray tube configured to emit an X-ray beam through an exit window to irradiate an object. The mobile X-ray unit may further include a dosimetry system adapted for real time dosimetry.

Abstract: An afterloading device for effectuating a brachytherapy treatment, comprising a first elongated flexible transport element, arranged to maneuver a radiation source between a storage position inside the afterloading device and a treatment position outside the afterloading device, the afterloading device further comprising a second elongated flexible transport element, having at least one transducer, the second transport element being arranged to move the at least one transducer between a first transducer position and a second transducer position.

Abstract: This invention relates to an assembly for performing brachytherapy treatment of tumour tissue in an animal body comprising at least a longitudinally extending intracavitary component and at least a guiding unit which extends at least partly parallel to said intracavitary component. Said guiding unit comprises at least one interstitial needle for guiding a radiation source into the tumour tissue. Said guiding unit is tubular over at least a longitudinal distance sufficient that in use a proximal end of said guiding unit is situated outside said body to be treated, while a distal end of said guiding unit is situated in situ close to or adjacent the tumour tissue.

Abstract: An embodiment of the present disclosure is directed to a brachytherapy source assembly including a guiding wire and a brachytherapy capsule located at a distal end of the guiding wire. The capsule includes a chamber defined by a wall for holding a radioactive source. At least a portion of an exterior surface of the wall of the capsule includes at least one of a friction-reducing coating, a wear-resistant coating, and a wear-indication coating a coating.

Abstract: The invention relates to a real time radiation treatment planning system for use in effecting radiation therapy of a pre-selected anatomical portion of an animal body using hollow needles. According to embodiments of the invention, the system may include a processing means processing means-configured to perform a three-dimensional imaging algorithm and a three-dimensional image segmentation algorithm, with respect to one or more specific organs within the pre-selected anatomical portion and with respect to the needles, for converting the image data obtained with an imaging means into a three-dimensional image of the anatomical portion, using at least one single or multi-objective anatomy-based genetic optimization algorithm.

Abstract: A modular applicator for enabling a brachytherapy treatment comprising a central element and one or more of peripheral elements, wherein the central element is adapted with a fixation mechanism having a core for affixing the said peripheral elements thereto, wherein the fixation mechanism prevents a rotational displacement of the peripheral elements attached to the core of the fixation element with respect to the central element.

Abstract: Embodiments of the present disclosure relate to a modular applicator for enabling a brachytherapy treatment, comprising a central core and an outer sleeve, wherein the central core is adapted with a fixation mechanism for affixing the outer sleeve to the central core, wherein the outer sleeve is manufactured from a substantially rigid or shapeable material.

Abstract: Embodiments of the disclosure relate to a method for reconstructing a spatial position of a conduit arranged to accommodate a radiotherapeutic radioactive source. The method includes displacing an object emitting radiation inside the conduit prior to the administration of a treatment, detecting said radiation using detectors; generating data upon detecting the said radiation using a processor; and reconstructing the spatial position of the conduit by the processor based on the said data to identify a delivery path of the treatment.

Abstract: The invention relates to a brachytherapy applicator device for insertion in a body cavity. The applicator device comprises an applicator shaped for insertion in the body cavity; the applicator comprising connectable segments; at least one connectable part having a form following wall surface shaped to follow the body cavity, the wall surface having a multichannel groove structure, so as to guide a plurality of catheters along the grooves in the groove structure along the wall surface.

Abstract: The invention relates to a real time radiation treatment planning system for use in effecting radiation therapy of a pre-selected anatomical portion of an animal body using hollow needles. According to embodiments of the invention, the system may include a processing means processing means-configured to perform a three-dimensional imaging algorithm and a three-dimensional image segmentation algorithm, with respect to one or more specific organs within the pre-selected anatomical portion and with respect to the needles, for converting the image data obtained with an imaging means into a three-dimensional image of the anatomical portion, using at least one single or multi-objective anatomy-based genetic optimization algorithm.

Abstract: The invention relates to a real time radiation treatment planning system for use in effecting radiation therapy of a pre-selected anatomical portion of an animal body using hollow needles. According to embodiments of the invention, the system may include a processing means processing means-configured to perform a three-dimensional imaging algorithm and a three-dimensional image segmentation algorithm, with respect to one or more specific organs within the pre-selected anatomical portion and with respect to the needles, for converting the image data obtained with an imaging means into a three-dimensional image of the anatomical portion, using at least one single or multi-objective anatomy-based genetic optimization algorithm.