Patents Assigned to Nuvelo, Inc.
  • hC1Q/TNF7 and uses thereof
    Publication number: 20050180949
    Abstract: The invention relates to pharmaceutical compositions comprising hC1Q/TNF7 polynucleotides and polypeptides. The invention further relates to the therapeutic use of hC1Q/TNF7 to prevent or treat conditions or disorders associated with wasting disorders, such as cachexia, or diseases associated with impaired growth.
    Type: Application
    Filed: February 11, 2005
    Publication date: August 18, 2005
    Applicant: NUVELO, Inc.
    Inventors: Peter Emtage, Shouchun Liu, Kerri Thai
  • Nucleic acids and polypeptides
    Patent number: 6919193
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Grant
    Filed: April 10, 2002
    Date of Patent: July 19, 2005
    Assignee: Nuvelo, Inc.
    Inventors: Y. Tom Tang, Ryle Goodrich, Chenghua Liu, Feiyan Ren, Dunrui Wang, Radoje T. Drmanac
  • Methods and materials relating to novel growth regulatory-like polypeptides and polynucleotides
    Publication number: 20050153334
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human growth regulatory-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human thymus (Hyseq clone identification number 16372272). Other aspects of the invention include vectors containing processes for producing novel human growth regulatory-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: December 2, 2004
    Publication date: July 14, 2005
    Applicant: NUVELO, Inc.
    Inventors: Nancy Mize, Bryan Boyle, John Ford, Matthew Arterburn, Y. Tang, Chenghua Liu, Radoje Drmanac, Yong Song, Michael Sjaastad
  • Methods and compositions relating to CD39-like polypeptides and nucleic acids
    Patent number: 6899875
    Abstract: The present invention provides novel polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides and polynucleotides of the invention comprise amino acid and nucleic acid sequences of novel CD39-like gene and gene products.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: May 31, 2005
    Assignee: Nuvelo, Inc.
    Inventors: Brian Paul Chadwick, Anna-Maria Frischauf
  • Methods and compositions relating to CD39-like polypeptides and nucleic acids
    Patent number: 6884872
    Abstract: The present invention provides polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides and polynucleotides of the invention comprise amino acid and nucleic acid sequences of novel CD39-like gene and gene products.
    Type: Grant
    Filed: July 13, 2001
    Date of Patent: April 26, 2005
    Assignee: NUVELO, Inc.
    Inventors: Brian Paul Chadwick, Anna-Maria Frischauf
  • Methods and materials relating to novel CD39-like polypeptides
    Patent number: 6858207
    Abstract: The invention provides novel polynucleotides isolated from cDNA libraries of human fetal liver-spleen and macrophage as well as polypeptides encoded by these polynucleotides and mutants or variants thereof. The polypeptides correspond to a novel human CD39-like protein. Other aspects of the invention include vectors containing polynucleotides of the invention and related host cells as well a processes for producing novel CD39-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: March 5, 2002
    Date of Patent: February 22, 2005
    Assignee: Nuvelo, Inc.
    Inventors: John Ford, Julio J. Mulero
  • Methods for selecting a therapy for a subject suffering from schizophrenia
    Patent number: 6833243
    Abstract: The invention features methods for diagnosing subjects at risk for or suffering from a disease or disorder, such as a psychosis. Methods are also provided for selecting a preferred therapy for a particular subject or group of subjects.
    Type: Grant
    Filed: August 16, 2001
    Date of Patent: December 21, 2004
    Assignee: Nuvelo, Inc.
    Inventor: Rima Rozen
  • Methods and compositions relating to CD39-like polypeptides and nucleic acids
    Patent number: 6828423
    Abstract: The present invention provides polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides and polynucleotides of the invention comprise amino acid and nucleic acid sequences of novel CD39-like gene and gene products.
    Type: Grant
    Filed: July 13, 2001
    Date of Patent: December 7, 2004
    Assignee: Nuvelo, Inc.
    Inventors: Brian Paul Chadwick, Anna-Maria Frischauf
  • Method of promoting stem cell proliferation or survival by contacting a cell with a stem cell factor-like polypeptide
    Patent number: 6824973
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human stem cell growth factor-like protein. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human testis cells (Hyseq clone identification numbers 2880984 and 2881695), from human fetal skin (Hyseq clone identification number 15375176), adult spleen (Hyseq clone identification number 14856094), and human endothelial cells (Hyseq clone identification numbers 13804756, 13687487, 13804756). Other aspects of the invention include vectors containing processes for producing novel human stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: November 30, 2004
    Assignees: Kirin Beer Kabushiki Kaisha, Nuvelo Inc.
    Inventors: Y. Tom Tang, Ivan Labat, Radoje T. Drmanac, Nancy Mize, Mitsuo Nishikawa, Cheng-Chi Chao
  • Methods and materials relating to semaphorin-like polynucleotides
    Patent number: 6818754
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted semaphorin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal liver-spleen (Hyseq clone identification numbers 5688868 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted semaphorin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: June 12, 2003
    Date of Patent: November 16, 2004
    Assignee: Nuvelo. Inc.
    Inventors: Bryan J. Boyle, George Yeung, Matthew C. Arterburn, Nancy K. Mize, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Method of detecting a cancerous cell expressing EGFL6, and EGF mutif protein
    Patent number: 6808890
    Abstract: The present invention provides novel polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides of the invention are useful for detecting cancers.
    Type: Grant
    Filed: October 15, 2001
    Date of Patent: October 26, 2004
    Assignee: Nuvelo, Inc.
    Inventors: John E. Ford, George Yeung, Hua Zhou
  • Methods and materials relating to alpha-2-macroglobulin-like polypeptides and polynucleotides
    Patent number: 6806254
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted alpha-2-macroglobulin-like polypeptides. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal brain mRNA (Clontech) (SEQ ID NO: 1) and uterus mRNA (Clontech) (SEQ ID NO: 26). Other aspects of the invention include vectors containing processes for producing novel human secreted alpha-2-macroglobulin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: January 8, 2001
    Date of Patent: October 19, 2004
    Assignee: Nuvelo, Inc.
    Inventors: Shubhada D. Godbole, Bryan J. Boyle, Nancy K. Mize, Cenhua Deng, Ryle W. Goodrich, Matthew C. Arterburn, Ping Zhou, Y. Tom Tang, Chenghua Liu, George Yeung, Radoje T. Drmanac
  • Method of detecting a cancerous cell expressing an EGF motif polynucleotide
    Patent number: 6800443
    Abstract: The present invention provides novel polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides of the invention are useful for detecting cancers.
    Type: Grant
    Filed: May 1, 2002
    Date of Patent: October 5, 2004
    Assignee: Nuvelo, Inc.
    Inventors: John E. Ford, George Yeung, Hua Zhou
  • Methods and compositions relating to CD39-like polypeptides and nucleic acids
    Patent number: 6787328
    Abstract: The present invention provides polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides and polynucleotides of the invention comprise amino acid and nucleic acid sequences of novel CD39-like gene and gene products.
    Type: Grant
    Filed: July 13, 2001
    Date of Patent: September 7, 2004
    Assignee: Nuvelo, Inc.
    Inventors: Brian Paul Chadwick, Anna-Maria Frischauf
  • Methods and compositions relating to CD39-like polypeptides and nucleic acids
    Patent number: 6783959
    Abstract: The present invention provides novel polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides and polynucleotides of the invention comprise amino acid and nucleic acid sequences of novel CD39-like gene and gene products.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: August 31, 2004
    Assignee: Nuvelo, Inc.
    Inventors: Brian Paul Chadwick, Anna-Maria Frischauf
  • Cathepsin V-like polypeptides
    Patent number: 6783969
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: August 31, 2004
    Assignee: Nuvelo, Inc.
    Inventors: Y. Tom Tang, Ryle W. Goodrich, Vinod Asundi, Radoje T. Drmanac
  • Methods and compositions relating to CD39-like polypeptides and nucleic acids
    Patent number: 6780410
    Abstract: The present invention provides polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides and polynucleotides of the invention comprise amino acid and nucleic acid sequences of novel CD39-like gene and gene products.
    Type: Grant
    Filed: July 13, 2001
    Date of Patent: August 24, 2004
    Assignee: Nuvelo, Inc.
    Inventors: Brian Paul Chadwick, Anna-Maria Frischauf
  • Methods and compositions relating to CD39-like polypeptides and nucleic acids
    Patent number: 6780977
    Abstract: The present invention provides novel polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides and polynucleotides of the invention comprise amino acid and nucleic acid sequences of novel CD39-like gene and gene products.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: August 24, 2004
    Assignee: Nuvelo, Inc.
    Inventors: Brian Paul Chadwick, Anna-Maria Frischauf
  • Thymidine phosphorylase gene sequence variances having utility in determining the treatment of disease
    Patent number: 6759200
    Abstract: The present disclosure describes the use of genetic variance information for folate transport or metabolism genes or pyrimidine transport or metabolism genes in the selection of effective methods of treatment of a disease or condition. The variance information is indicative of the expected response of a patient to a method of treatment. Methods of determining relevant variance information and additional methods of using such variance information are also described.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: July 6, 2004
    Assignee: Nuvelo, Inc.
    Inventor: Vincent P. Stanton, Jr.
  • Methods and compositions relating to CD39-like polypeptides and nucleic acids
    Patent number: 6759214
    Abstract: The present invention provides polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides and polynucleotides of the invention comprise amino acid and nucleic acid sequences of novel CD39-like gene and gene products.
    Type: Grant
    Filed: July 13, 2001
    Date of Patent: July 6, 2004
    Assignee: Nuvelo, Inc.
    Inventors: Brian Paul Chadwick, Anna-Maria Frischauf