Patents Assigned to Nuvelo, Inc.
  • Growth factor antagonist materials and methods
    Patent number: 6706871
    Abstract: The present invention provides nucleic acids encoding Sprouty related human growth factor antagonist proteins (designated FGFAn-Hy), the polypeptides encoded by these nucleic acids and uses of these and related products.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: March 16, 2004
    Assignee: Nuvelo, Inc.
    Inventors: Dennis G. Ballinger, Julie Reeder Montgomery
  • Methods for targeting RNA molecules
    Patent number: 6686148
    Abstract: Methods are described for identifying an RNA target for an allele-specific RNA inhibitor by identifying a sequence variance in an RNA encoded by a gene of interest, and determining whether the secondary structure of the RNA comprising the variance differs from that of an otherwise identical RNA not comprising the variance.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: February 3, 2004
    Assignee: Nuvelo, Inc.
    Inventors: Ling X. Shen, Gregory L. Verdine, James P. Basilion, Vincent P. Stanton, Jr.
  • Tumor necrosis factor receptor 2
    Patent number: 6673908
    Abstract: The present disclosure describes the use of genetic variance information for genes involved in inflammatory or immunologic disease, disorder, or dysfunction. The variance information is indicative of the expected response of a patient to a method of treatment. Methods of determining relevant variance information and additional methods of using such variance information are also described.
    Type: Grant
    Filed: October 1, 2001
    Date of Patent: January 6, 2004
    Assignee: Nuvelo, Inc.
    Inventor: Vincent P. Stanton, Jr.
  • Thymidylate synthase gene sequence variances having utility in determining the treatment of disease
    Patent number: 6664062
    Abstract: The present disclosure describes the use of genetic variance information for folate transport or metabolism genes or pyrimidine transport or metabolism genes in the selection of effective methods of treatment of a disease or condition. The variance information is indicative of the expected response of a patient to a method of treatment. Methods of determining relevant variance information and additional methods of using such variance information are also described.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: December 16, 2003
    Assignee: Nuvelo, Inc.
    Inventor: Vincent P. Stanton, Jr.
  • Antibodies specific for semaphorin-like polypeptides
    Patent number: 6635742
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted semaphorin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal liver-spleen (Hyseq clone identification numbers 5688868 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted semaphorin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: August 31, 2000
    Date of Patent: October 21, 2003
    Assignee: Nuvelo, Inc.
    Inventors: Bryan J. Boyle, George Yeung, Matthew C. Arterburn, Nancy K. Mize, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Nucleic acids and polypeptides
    Patent number: 6610536
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Grant
    Filed: March 14, 2001
    Date of Patent: August 26, 2003
    Assignee: NUVELO, Inc.
    Inventors: Y. Tom Tang, Ryle Goodrich, Vinod Asundi, Radoje T. Drmanac
  • Genotyping of the paraoxonase 1 gene for prognosing, diagnosing, and treating a disease
    Patent number: 6573049
    Abstract: The invention provides methods for identifying or stratifying subjects having Alzheimer's disease or at risk for Alzheimer's disease by determining the genotype at nucleotide 172 of the PON1 allele of the subject.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: June 3, 2003
    Assignee: Nuvelo, Inc.
    Inventor: Keith Schappert