Patents Assigned to NxStage Medical, Inc.
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Patent number: 11071814Abstract: A core temperature measurement may be made by varying the heat transfer dynamics of a blood circuit and fitting parameters of a blood circuit heat transfer configuration to measurements under the varied conditions. Then the input temperature of the patient core can be extracted from the model and a current temperature measurement remote from the patient core and optionally other measurements such as blood flow rate.Type: GrantFiled: April 18, 2019Date of Patent: July 27, 2021Assignee: NxStage Medical, Inc.Inventors: Scott W. Newell, Dennis M. Treu, Jerome James
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Publication number: 20210213191Abstract: Simple-to-use systems, methods, and devices for priming replacement blood treatment devices, for swapping the blood treatment devices out, for replacing swapped-out blood treatment devices, and other related operations are described. In embodiments, a blood treatment device can be primed while a therapy is still running. When the replacement blood treatment device is needed, the therapy can be stopped momentarily (less than a minute) for the rapid and safe swap of the blood treatment device. Blood loss can be minimized. The down time from therapy can be minimized.Type: ApplicationFiled: March 31, 2021Publication date: July 15, 2021Applicant: NxStage Medical, Inc.Inventors: James M. BRUGGER, David DESOUZA
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Publication number: 20210205519Abstract: A fluid treatment plant has a filter module including at least a first filter and a second filter connected in series and connectable to a supply of fluid. A pump is fluidly connected to the filter module and a controller with a fluid quality sensor is connected to detect a quality of the fluid between the first filter and the second filter. A filter module detector is connected to the controller configured to uniquely detect a filter module connected to the pump, and the controller is controls the pump responsively to a signal from the fluid quality sensor and the module detector. The controller is configured to continue pumping based on output of the quality sensor and/or based on output from the filter module detector.Type: ApplicationFiled: March 25, 2021Publication date: July 8, 2021Applicant: NxStage Medical, Inc.Inventors: Jeffrey H. BURBANK, Dennis M. TREU, Goetz FRIEDERICHS, Brian C. GREEN, Christopher S. MCDOWELL, James M. BRUGGER
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Publication number: 20210178041Abstract: A method of automatically ensuring against chloramine contamination in purified product water includes supplying input water to the system and purifying the water to generate the purified product water. The purifying includes removing chlorine and chloramine contamination from the water using a carbon filter and supplying chlorine-depleted water to a deionization filter, and deionizing the chlorine-depleted water using said deionization filter. The product water is supplied to a sensor for continuous monitoring of the resistivity of the purified product water by the first sensor, and an alarm is generated indicating possible chloramine breakthrough when the resistivity of the product water falls below a predetermined resistivity level, which is selected to provide a reserve filter capacity before breakthrough would occur. The carbon filter is replaced at least responsively to the alarm to ensure excess capacity of said carbon filter sufficient to prevent chloramine breakthrough in said product water.Type: ApplicationFiled: March 2, 2021Publication date: June 17, 2021Applicant: NxStage Medical, Inc.Inventors: Goetz FRIEDERICHS, Dennis M. TREU, Jeffrey H. BURBANK, Yuriy N. TATASHIN
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Publication number: 20210163320Abstract: A fluid purification system has cells whose purifying capability can be regenerated. Some of the cells are arranged in series to reach a high level of purification. An automatic valve network is controlled to cycle the cells in a way that levels the loads on each, thereby maximizing the service interval for replacing expired cells, enabling all of the cells to be replaced at the same time after having each contributing approximately equally to the purification load, and operated such that at any one time, at least one cell is regenerated so as to enable continuous up-time.Type: ApplicationFiled: February 16, 2021Publication date: June 3, 2021Applicant: NxStage Medical, Inc.Inventors: Joseph E. TURK, JR., William K. WEIGEL, Goetz FRIEDERICHS, Jeffery B. HOVER, SR.
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Publication number: 20210128812Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.Type: ApplicationFiled: December 15, 2020Publication date: May 6, 2021Applicant: NxStage Medical, Inc.Inventors: David DESOUZA, Daniel Joseph RUBERY, JR., Dennis M. TREU, Mark T. WYETH, Jerome JAMES, Garrett D. CASEY, James M. BRUGGER, William J. SCHNELL, Jeffrey H. BURBANK, Goetz FRIEDERICHS
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Patent number: 10994067Abstract: A system associated with a medical treatment device for detecting a condition of a patient includes an input device including at least a camera or a microphone. The system also includes a medical treatment device with a controller/classifier and at least one of flow controller, a pump, and/or an alarm output. The controller/classifier has at least a video-image processor or an audio processor configured to recognize a face and a body or to recognize changes in skin color, facial expression, or body position. The controller/classifier may also recognize speech and classify predefined normal and irregular sound patterns, and output state data corresponding thereto. The controller/classifier is connected to apply the state data to the at least one flow controller, pump, and/or alarm output.Type: GrantFiled: November 9, 2018Date of Patent: May 4, 2021Assignee: NxStage Medical, Inc.Inventors: Jeffrey H. Burbank, James M. Brugger
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Publication number: 20210125715Abstract: An automatic monitoring system for a medical treatment device helps to ensure that an a medical treatment device operated at a treatment location away from a clinic is preformed safely. The monitoring system may verify that an assistant is present during treatment of the patient. Among the features disclosed biometric authentication to verify that a trained assistant is present, a presence detector to ensure the assistant is continuously present during treatment, and warning and recovery processes that allow intermittent lapses in the continuous presence of the assistant. The treatment device also communicates with a remote server or terminal.Type: ApplicationFiled: December 31, 2020Publication date: April 29, 2021Applicant: NxStage Medical, Inc.Inventors: Jeffrey H. BURBANK, Dennis M. TREU, James M. BRUGGER
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Patent number: 10987461Abstract: Simple-to-use systems, methods, and devices for priming replacement blood treatment devices, for swapping the blood treatment devices out, for replacing swapped-out blood treatment devices, and other related operations are described. In embodiments, a blood treatment device can be primed while a therapy is still running. When the replacement blood treatment device is needed, the therapy can be stopped momentarily (less than a minute) for the rapid and safe swap of the blood treatment device. Blood loss can be minimized. The down time from therapy can be minimized.Type: GrantFiled: March 27, 2019Date of Patent: April 27, 2021Assignee: NxStage Medical, Inc.Inventors: James M. Brugger, David Desouza
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Publication number: 20210113756Abstract: A medical treatment system includes a disposable fluid circuit that includes a water inlet and a batch container arranged to hold a mixture, the mixture including water that is received from the water inlet and at least one concentrate. The fluid circuit also includes a drain line for draining fluid from the disposable fluid circuit, and a configurable fluid pathway with a plurality of fluid lines, the configurable fluid pathway connecting the water inlet, the batch container, a source of the at least one concentrate, and the drain line. A source of purified water supplies the purified water to the water inlet and a sensor detects a property of fluid in the disposable fluid circuit. A controller controls flowing of a first fluid followed by displacement by a second fluid causing the first fluid to flow to the sensor.Type: ApplicationFiled: December 23, 2020Publication date: April 22, 2021Applicant: NxStage Medical, Inc.Inventors: Jeffrey H. BURBANK, James M. BRUGGER, Dennis M. TREU, Mark T. WYETH
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Patent number: 10973969Abstract: A fluid preparation system has a sealed sterilized fluid circuit with a sealed sterilized container with a conductivity sensor in communication with an interior of said container. Further, at least one sealed connector is adapted for adding fluid to said container, and at least one sealed connector is adapted for removing fluid from said container. The conductivity sensor is contained in a test line in communication with said interior and is adapted to be connected to a source of suction thereby to draw a sample of contents of said container. Furthermore, the test line may have a check valve to prevent ingress of contaminants into said container, and the sealed connector is adapted for adding fluid to said container and may have an inline sterile filter. Furthermore, the system may have a controller that controls pumping actuators.Type: GrantFiled: May 28, 2019Date of Patent: April 13, 2021Assignee: NxStage Medical, Inc.Inventors: Jeffrey H. Burbank, Dennis M. Treu, Goetz Friederichs, Brian C. Green, Christopher S. McDowell, James M. Brugger
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Patent number: 10960121Abstract: A method of automatically ensuring against chloramine contamination in purified product water includes supplying input water to the system and purifying the water to generate the purified product water. The purifying includes removing chlorine and chloramine contamination from the water using a carbon filter and supplying chlorine-depleted water to a deionization filter, and deionizing the chlorine-depleted water using said deionization filter. The product water is supplied to a sensor for continuous monitoring of the resistivity of the purified product water by the first sensor, and an alarm is generated indicating possible chloramine breakthrough when the resistivity of the product water falls below a predetermined resistivity level, which is selected to provide a reserve filter capacity before breakthrough would occur. The carbon filter is replaced at least responsively to the alarm to ensure excess capacity of said carbon filter sufficient to prevent chloramine breakthrough in said product water.Type: GrantFiled: March 19, 2018Date of Patent: March 30, 2021Assignee: NxStage Medical, Inc.Inventors: Goetz Friederichs, Dennis M. Treu, Jeffrey H. Burbank, Yuriy N. Tatashin
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Patent number: 10947135Abstract: A fluid purification system has cells whose purifying capability can be regenerated. Some of the cells are arranged in series to reach a high level of purification. An automatic valve network is controlled to cycle the cells in a way that levels the loads on each, thereby maximizing the service interval for replacing expired cells, enabling all of the cells to be replaced at the same time after having each contributing approximately equally to the purification load, and operated such that at any one time, at least one cell is regenerated so as to enable continuous up-time.Type: GrantFiled: November 27, 2018Date of Patent: March 16, 2021Assignee: NxStage Medical, Inc.Inventors: Joseph E. Turk, Jr., William K. Weigel, Goetz Friederichs, Jeffery B. Hover
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Publication number: 20210060226Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.Type: ApplicationFiled: November 13, 2020Publication date: March 4, 2021Applicant: NxStage Medical, Inc.Inventors: Jeffrey H. BURBANK, Dennis M. TREU, Daniel Joseph RUBERY, JR., Scott W. NEWELL, James M. BRUGGER, William J. SCHNELL, William K. WEIGEL, Steven A. WHITE, Mark T. WYETH, Jerome JAMES, David DESOUZA, Joseph E. TURK, JR., Garrett CASEY
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Patent number: 10926021Abstract: Methods, systems, and devices are disclosed, embodiments of which provide single pass dialysis to remove water and uremic toxins is performed simultaneously with the albumin dialysis therapy by passing the albumin solution through a dialysis filter which dialyses it before the solution is returned to the cycler. In embodiments, the single pass dialysis stage is upstream of the albumin filtering stage.Type: GrantFiled: October 22, 2018Date of Patent: February 23, 2021Assignee: NXSTAGE MEDICAL, INC.Inventors: William K. Weigel, Joseph E. Turk, Jr., Jan Stange, Dennis M. Treu
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Patent number: 10926016Abstract: A system that fills multiple containers includes a filter with an inlet port and multiple outlet ports. The outlet ports are pre-attached to containers by respective filling lines of each container. Each container has an interior and each of the respective filling lines is connected to a respective container interior. All of the respective filling lines are sealed to the outlet ports and the containers such that the container interiors are isolated from an external environment except the inlet port, via the filter, forming a combined interior volume which is sterile. The system can produce batches of multiple sterile containers with sterile medicament in the containers.Type: GrantFiled: March 30, 2017Date of Patent: February 23, 2021Assignee: NXSTAGE MEDICAL, INC.Inventors: Jeffrey H. Burbank, James M. Brugger
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Publication number: 20210023291Abstract: According to embodiments, priming systems, methods, and devices are disclosed which allow medical treatment devices which pump fluid to be primed with minimal operator intervention and a high level of convenience. A blood circuit with a filter fitted with one or more air vents on a non-blood compartment is attached to a treatment system and priming fluid pumped slowly through the blood circuit in a loop. The source of fluid may be elevated, or the pumping may generate pressure, such that priming fluid is forced through the membrane of the filter and out the air vent(s). In embodiments, the vents are hydrophobic which prevent fluid from being ejected, so the priming system can run without intervention.Type: ApplicationFiled: October 8, 2020Publication date: January 28, 2021Applicant: NxStage Medical, Inc.Inventors: James M. BRUGGER, William J. SCHNELL
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Patent number: 10898635Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.Type: GrantFiled: July 18, 2017Date of Patent: January 26, 2021Assignee: NxStage Medical, Inc.Inventors: David Desouza, Daniel J. Rubery, Jr., Dennis M. Treu, Mark T. Wyeth, Jerome James, Garrett D. Casey, James M. Brugger, William J. Schnell, Jeffrey H. Burbank, Goetz Friederichs
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Patent number: 10898630Abstract: An automated peritoneal dialysis system provides both cycler-assisted peritoneal dialysis treatment. The system includes a fluid preparation and treatment device with concentrate dilution components connected to a source of purified water and medicament concentrate. The treatment device has at least one mixing container connected via a pump and valves to the sources, the valves and the pump mixing and diluting the concentrate to form a medicament. Conductivity sensors are provided for fluid quality measurement, calibration, error trapping, and fluid characterization.Type: GrantFiled: May 11, 2018Date of Patent: January 26, 2021Assignee: NxStage Medical, Inc.Inventors: Jeffrey H. Burbank, James M. Brugger, Dennis M. Treu, Mark T. Wyeth
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Patent number: 10895339Abstract: The disclosed subject matter includes embodiments of fluid couplings that prevent or discourage misconnection of fluid lines. In embodiments, a coupling device may be configured according to lookup table that defines compatible configurations of connectors. The configurations may be based on the presence and absence of interference members at standardized locations on the respective connectors. The interference members may include posts that mechanically interfere with other posts, but can be inserted into holes when two connectors have a compatible configuration.Type: GrantFiled: November 9, 2018Date of Patent: January 19, 2021Assignee: NxStage Medical, Inc.Inventors: James M. Brugger, Dennis M. Treu, David S. Utterberg