Patents Assigned to NxStage Medical, Inc.
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Patent number: 10869958Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.Type: GrantFiled: April 11, 2019Date of Patent: December 22, 2020Assignee: NxStage Medical, Inc.Inventors: Jeffrey H. Burbank, Dennis M. Treu, Daniel J. Rubery, Jr., Scott W. Newell, James M. Brugger, William J. Schnell, William K. Weigel, Steven A. White, Mark T. Wyeth, Jerome James, David Desouza, Joseph E. Turk, Jr., Garrett Casey
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Publication number: 20200386625Abstract: A system for measuring electrical conductivity includes a fluid conduction measuring circuit and a temperature measuring element having at least one thermal contact portion with a temperature sensor and a temperature measuring circuit. A controller is configured to control the conduction measuring circuit and the temperature measuring element. A fluid circuit is configured to carry a fluid and has a wetted conductor inside a conductivity cell portion, the wetted conductor having a contact, external to the fluid circuit, for interfacing with the fluid conduction measuring circuit. Further, at least one temperature measurement portion has predefined thermal properties and is configured to touch the thermal contact portion. The controller controls the temperature measuring element and the conduction measuring circuit to generate and output at least one set of contemporaneous temperature and conduction measurements.Type: ApplicationFiled: August 25, 2020Publication date: December 10, 2020Applicant: NxStage Medical, Inc.Inventors: Scott W. NEWELL, Yakov KOGAN
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Patent number: 10835657Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.Type: GrantFiled: April 11, 2019Date of Patent: November 17, 2020Assignee: NxStage Medical, Inc.Inventors: Jeffrey H. Burbank, Dennis M. Treu, Daniel J. Rubery, Jr., Scott W. Newell, James M. Brugger, William J. Schnell, William K. Weigel, Steven A. White, Mark T. Wyeth, Jerome James, David Desouza, Joseph E. Turk, Jr., Garrett Casey
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Patent number: 10835658Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.Type: GrantFiled: April 11, 2019Date of Patent: November 17, 2020Assignee: NxStage Medical, Inc.Inventors: Jeffrey H. Burbank, Dennis M. Treu, Daniel J. Rubery, Jr., Scott W. Newell, James M. Brugger, William J. Schnell, William K. Weigel, Steven A. White, Mark T. Wyeth, Jerome James, David Desouza, Joseph E. Turk, Jr., Garrett Casey
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Patent number: 10835659Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.Type: GrantFiled: April 11, 2019Date of Patent: November 17, 2020Assignee: NxStage Medical, Inc.Inventors: Jeffrey H. Burbank, Dennis M. Treu, Daniel J. Rubery, Jr., Scott W. Newell, James M. Brugger, William J. Schnell, William K. Weigel, Steven A. White, Mark T. Wyeth, Jerome James, David Desouza, Joseph E. Turk, Jr., Garrett Casey
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Patent number: 10835662Abstract: According to embodiments, priming systems, methods, and devices are disclosed which allow medical treatment devices which pump fluid to be primed with minimal operator intervention and a high level of convenience. A blood circuit with a filter fitted with one or more air vents on a non-blood compartment is attached to a treatment system and priming fluid pumped slowly through the blood circuit in a loop. The source of fluid may be elevated, or the pumping may generate pressure, such that priming fluid is forced through the membrane of the filter and out the air vent(s). In embodiments, the vents are hydrophobic which prevent fluid from being ejected, so the priming system can run without intervention.Type: GrantFiled: May 11, 2018Date of Patent: November 17, 2020Assignee: NxStage Medical, Inc.Inventors: James M. Brugger, William J. Schnell
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Publication number: 20200289733Abstract: A system for filling multiple sterile containers includes a filter with an inlet port and multiple outlet ports, the outlet ports being pre-attached to sterile containers by respective filling lines of each container. Each container has an interior and each of the respective filling lines are connected to a respective container interior. The respective filling lines are sealed to the outlet ports and the containers such that the container interiors are isolated from an external environment except the inlet port, via the filter, forming a combined interior volume which is sterile. A container that is connectable to an outlet port the system has a bladder, a first tube and a second tube connected to the bladder, and a sterilizing filter. The container, the first tube and the second tube, and the sterilizing filter are sterile before water is flowed through the sterilizing filter into the bladder.Type: ApplicationFiled: June 2, 2020Publication date: September 17, 2020Applicant: NxStage Medical, Inc.Inventors: Jeffrey H. BURBANK, James M. BRUGGER
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Publication number: 20200284471Abstract: A low leakage current fluid heater and systems and methods thereof. The fluid heater has a configuration whereby a heating element is isolated from a fluid channel so as to leak into fluid passing through the channel an allowed amount of leakage current. Fluid passing through the fluid heater can be heated to a desired temperature. A controller can provide control signals to driver the fluid heater to the desired temperature and maintain the temperature at the desired temperature.Type: ApplicationFiled: May 27, 2020Publication date: September 10, 2020Applicant: NxStage Medical, Inc.Inventor: Scott W. NEWELL
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Patent number: 10760974Abstract: A system for measuring electrical conductivity includes a fluid conduction measuring circuit and a temperature measuring element having at least one thermal contact portion with a temperature sensor and a temperature measuring circuit. A controller is configured to control the conduction measuring circuit and the temperature measuring element. A fluid circuit is configured to carry a fluid and has a wetted conductor inside a conductivity cell portion, the wetted conductor having a contact, external to the fluid circuit, for interfacing with the fluid conduction measuring circuit. Further, at least one temperature measurement portion has predefined thermal properties and is configured to touch the thermal contact portion. The controller controls the temperature measuring element and the conduction measuring circuit to generate and output at least one set of contemporaneous temperature and conduction measurements.Type: GrantFiled: November 18, 2017Date of Patent: September 1, 2020Assignee: NxStage Medical, Inc.Inventors: Scott W. Newell, Yakov Kogan
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Publication number: 20200230309Abstract: A blood treatment system employing at least two pumps for performing a low blood flow treatment is operable for high blood flow treatments such as extracorporeal membrane oxygenation (ECMO) by providing a fluid circuit with parallel blood flow paths and recruiting multiple ones of the pumps for parallel blood flow.Type: ApplicationFiled: February 5, 2018Publication date: July 23, 2020Applicant: NxStage Medical, Inc.Inventor: Dennis M. TREU
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Publication number: 20200206405Abstract: A blood treatment system with pressure sensors may be configured to control blood flow to and from the patient and use readings of the pressure sensors to determine a change in a pressure drop across a flow restriction in the blood circuit to estimate a condition of the machine or the patient, or outputting data responsive to the estimation. Further embodiments employ measurement of pressure drop to detect abnormal viscosity or viscosity variations in order to detect possible infection.Type: ApplicationFiled: August 30, 2017Publication date: July 2, 2020Applicant: NxStage Medical, Inc.Inventors: Mark T. WYETH, Robert Paul MCCARTY, Gregory YANTZ, James Ian JOHNSON, Joseph E. TURK, Jr., James M. BRUGGER, Jeffrey H. BURBANK
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Patent number: 10697667Abstract: A low leakage current fluid heater and systems and methods thereof. The fluid heater has a configuration whereby a heating element is isolated from a fluid channel so as to leak into fluid passing through the channel an allowed amount of leakage current. Fluid passing through the fluid heater can be heated to a desired temperature. A controller can provide control signals to driver the fluid heater to the desired temperature and maintain the temperature at the desired temperature.Type: GrantFiled: January 12, 2018Date of Patent: June 30, 2020Assignee: NxStage Medical, Inc.Inventor: Scott W Newell
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Patent number: 10688235Abstract: A method of performing a dialysis treatment includes using a pump and a dialysate supply line to transport peritoneal dialysis fluid, the supply line having a proximal end into which peritoneal dialysis fluid is supplied and from which spend dialysate is withdrawn, and a distal end which is connected to a patient's peritoneal access. The method further includes generating proximal and distal pressure signals using pressure detectors located at both the proximal and distal ends, respectively, of said supply line. During a drain cycle in which spent dialysate is pumped from the patient, the method includes, responsively to the proximal and distal pressure signals, detecting a characteristic of a pressure difference between the distal and proximal ends whose magnitude is determined by a predicted change in dialysate properties, and responsively to the characteristic, generating a signal indicating the change in dialysate properties.Type: GrantFiled: March 31, 2017Date of Patent: June 23, 2020Assignee: NxStage Medical, Inc.Inventors: Jeffrey H. Burbank, James M. Brugger, Dennis M. Treu, Mark T. Wyeth
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Patent number: 10688234Abstract: A method of performing a peritoneal dialysis treatment includes connecting a disposable unit to a source of water. The disposable unit includes at least a first container holding a sterile concentrate containing an osmotic agent, a second container holding a sterile concentrate containing electrolytes, an empty sterile mixing container, and a tubing set with a pre-attached peritoneal fill/drain line. The method also includes receiving a prescription command by a controller, indicating at least the fill volume and desired final concentration of the osmotic agent to be used for a current fill cycle under said treatment, and pumping a quantity of the concentrated osmotic agent that is at least sufficient to achieve the desired final concentration into the mixing container. The contest of the mixing container are mixed, further diluted or concentrated, and then flowed to a patient.Type: GrantFiled: March 31, 2017Date of Patent: June 23, 2020Assignee: NxStage Medical, Inc.Inventors: Jeffrey H. Burbank, James M. Brugger, Dennis M. Treu, Mark T. Wyeth
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Publication number: 20200171230Abstract: A medicament preparation system includes a disposable cartridge with a flow path. Various sensors may be placed on the cartridge to measure qualities of the fluid flowing through the flow path. The sensors are placed in precise locations using various approaches that make manufacturing of the cartridge efficient and repeatable. A drain line that is susceptible to fouling may be preattached and various approaches are used to remove or reduce the fouling. An elastomeric contact can also be present in the medical preparation system and used in a conductivity measurement subsystem.Type: ApplicationFiled: June 24, 2018Publication date: June 4, 2020Applicant: NxStage Medical, Inc.Inventors: James M. BRUGGER, Jeffrey H. BURBANK, Goetz FRIEDERICHS, Scott W. NEWELL, William J. SCHNELL, Orlando SOTO
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Patent number: 10668206Abstract: A core temperature measurement may be made by varying the heat transfer dynamics of a blood circuit and fitting parameters of a blood circuit heat transfer configuration to measurements under the varied conditions. Then the input temperature of the patient core can be extracted from the model and a current temperature measurement remote from the patient core and optionally other measurements such as blood flow rate.Type: GrantFiled: October 8, 2016Date of Patent: June 2, 2020Assignee: NxStage Medical, Inc.Inventors: Scott W. Newell, Dennis M. Treu, Jerome James
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Publication number: 20200155747Abstract: A conductivity measurement device includes first and second conductivity measurement flow channels positioned in a fluid circuit and fluidly linked for fluid flow between the first and second conductivity measurement flow channels. A controller having a current source connected to the first and second conductivity channels applies alternating voltages at frequencies that are different, each being respective to one of the first and second conductivity cells.Type: ApplicationFiled: December 12, 2019Publication date: May 21, 2020Applicant: NxStage Medical, Inc.Inventors: Orlando SOTO, Joseph RAUSA, James M. BRUGGER, William J. SCHNELL, Goetz FRIEDERICHS, Jeffrey H. BURBANK, Joseph E. TURK, JR., Scott W. NEWELL, Amanda WOZNIAK
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Publication number: 20200114061Abstract: Features for protecting against leaks in a fluid circuit are disclosed. In an embodiment, a first indicator of a leak is used to trigger confirmation by blood flow reversal and air detection in the blood circuit. A method for performing a blood treatment includes, at blood treatment machine, pumping blood to a patient through a first blood line. Further, at a controller of the blood treatment machine, a first signal is received, indicating a probability of a leak in the first blood line. Responsively to the first signal, the controller commands a leak verification operation and receives a second signal indicating whether a leak in the first blood line is verified. Further, a leak indicating signal is generated if the second signal indicates a leak is verified.Type: ApplicationFiled: December 16, 2019Publication date: April 16, 2020Applicant: NxStage Medical, Inc.Inventors: Jeffrey H. BURBANK, Dennis M. TREU, James M. BRUGGER, Daniel Joseph RUBERY, JR.
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Patent number: 10610630Abstract: A method of performing a peritoneal dialysis treatment includes connecting a disposable unit to a source of water, the disposable unit including at least a first container holding a sterile concentrate containing an osmotic agent, a second container holding a sterile concentrate containing electrolytes, an empty sterile mixing container, and a tubing set with a pre-attached peritoneal fill/drain line. The method further includes receiving a prescription command by a controller, indicating at least the fill volume and desired final concentration of the osmotic agent to be used for a current fill cycle under said treatment, and using the controller, pumping a quantity of the concentrated osmotic agent that is at least sufficient to achieve the desired final concentration into the mixing container. The contents of the mixing container are mixed, further diluted or concentrated, and then flowed to a patient.Type: GrantFiled: March 31, 2017Date of Patent: April 7, 2020Assignee: NxStage Medical, Inc.Inventors: Jeffrey H. Burbank, James M. Brugger, Dennis M. Treu, Mark T. Wyeth
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Patent number: 10603424Abstract: A disposable fluid circuit used in a medical device that performs peritoneal dialysis includes a peritoneal dialysis tubing set that has a connection tube with a connector for a peritoneal catheter at a distal end and a connector configured to connect to a peritoneal cycler at a proximal end. The circuit also includes a pressure pod at the distal end, the pressure pod being of the type that has a flow chamber for carrying a liquid and an air chamber separated from the flow chamber by a diaphragm and an air port in fluid communication with the air chamber. The flow chamber is connected in-line with a lumen of the connection tube and a length of tubing runs from the air-port along the length of the connection tube with a connector at the proximal end configured to connect to a pressure transducer.Type: GrantFiled: March 31, 2017Date of Patent: March 31, 2020Assignee: NxStage Medical, Inc.Inventors: Jeffrey H. Burbank, James M. Brugger, Dennis M. Treu, Mark T. Wyeth