Patents Assigned to Nycomed Pharma AS
  • Patent number: 5643438
    Abstract: The invention relates to a new process for the preparation of substituted diaminodicarboxylic acid derivatives of the formula ##STR1## in a high yield by a modified Kolbe synthesis.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: July 1, 1997
    Assignee: Hafslund Nycomed Pharma Aktiengesellschaft
    Inventors: Johann Hiebl, Franz Rovenszky
  • Patent number: 5627198
    Abstract: The invention relates to heterocyclic amides of the formula ##STR1## in which the radicals A, Z, A.sub.1, R.sub.1, R.sub.2 and R.sub.3 are as defined in the description, to a process for the preparation of these amides and to their use as active substances for the curing and amelioration of disorders and diseases which can be treated by exerting influence on potassium channels.
    Type: Grant
    Filed: December 4, 1995
    Date of Patent: May 6, 1997
    Assignee: Hafslund Nycomed Pharma Aktiengesellschaft
    Inventors: Peter Esch, Robertson Towart, Franz Rovenszky
  • Patent number: 5627302
    Abstract: The invention relates to novel asymmetrically substituted diaminodicarboxylic acid derivatives of the formula ##STR1##
    Type: Grant
    Filed: April 24, 1996
    Date of Patent: May 6, 1997
    Assignee: Hafslund Nycomed Pharma Aktiengesellschaft
    Inventors: Johann Hiebl, Franz Rovenszky
  • Patent number: 5554618
    Abstract: An intravenously administrable, aqueous solution of a water-soluble, physiologically tolerable salt of sulfametrole and of trimethoprim, in which malic acid, L-serine and/or L-threonine are present as solubilizers, and which has a pH of of 6.5-7.0 is disclosed.
    Type: Grant
    Filed: September 14, 1994
    Date of Patent: September 10, 1996
    Assignee: Hafslund Nycomed Pharma Aktiengesellschaft
    Inventor: Karl Groke
  • Patent number: 5537213
    Abstract: Light measurement apparatus includes an elongate member which has at one end thereof light emitter(s) and light detector(s). At least the end of the elongate member that has the light emitter(s) and light detector(s) is surrounded by a resiliently biased sheath. In use, when the elongate member is applied to a surface to take a reading, the sheath defines a light-tight enclosure. A related method for determining intensity and/or color of a colored spot on a surface of a test site uses the light measurement apparatus. The method includes bringing the end of the elongate member into contact with the surface, pressing the resiliently biased sheath towards the surface to define a light-tight enclosure, and measuring the intensity and/or color of the colored spot on the surface.
    Type: Grant
    Filed: December 23, 1994
    Date of Patent: July 16, 1996
    Assignee: Nycomed Pharma AS
    Inventors: Torstein Seim, Stig M. Borch
  • Patent number: 5206420
    Abstract: Preparation of succinylcholine halides of formula I: ##STR1## by reacting dialkyl succinates with an excess dimethylaminoethanol in the presence of an alkali metal alcoholate or alkali metal amide catalyst and then reacting the resulting bis(2-dimethylaminoethyl) succinates with methyl halides.
    Type: Grant
    Filed: June 24, 1992
    Date of Patent: April 27, 1993
    Assignee: Hafslund Nycomed Pharma Aktiengesellschaft
    Inventors: Walter Raml, Gunther Eichberger
  • Patent number: 5155099
    Abstract: Compounds of formula I ##STR1## in which R denotes a straight-chain or branched, saturated or unsaturated aliphatic hydrocarbon radical having 6-30 C atoms wich may optionally be substituted by halogen or the radicals OR.sub.1, SR.sub.1 or NR.sub.1 R.sub.2, where R.sub.1 and R.sub.2 in each case denote a hydrogen atom or an alkyl or acyl radical having 1-6 C atoms which have excellent virustatic and cytostatic action.
    Type: Grant
    Filed: October 19, 1990
    Date of Patent: October 13, 1992
    Assignee: Hafslund Nycomed Pharma Aktiengesellschaft
    Inventors: Hans Brachwitz, Reinhild Schonfeld, Peter Langen, Friedrich Paltauf, Albin Hermetter
  • Patent number: 5138072
    Abstract: Process for the preparation of 5-chloro-3-chlorosulphonyl-2-thiophenecarboxylic acid esters by chlorination in the presence of activated iron.
    Type: Grant
    Filed: December 2, 1991
    Date of Patent: August 11, 1992
    Assignee: Hafslund Nycomed Pharma Aktiengesellschaft
    Inventor: Hans P. Wagner
  • Patent number: 5051439
    Abstract: Allylaminoethyltriazoles of the formula: ##STR1## in which R is a hydrogen atom or an alkyl group containing 1 to 5 carbon atoms; each of Ar and Ar' is an unsubstituted phenyl group, a phenyl group substituted by one or more substituents selected from C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkoxy, nitro and halogen, an unsubstituted thienyl group, or a thienyl group substituted by halogen or naphthyl; phytophysiologically or pharmacologically tolerated acid addition salts thereof; and fungicidal and antimycotic agents containing such compounds.
    Type: Grant
    Filed: July 5, 1990
    Date of Patent: September 24, 1991
    Assignee: Hafslund Nycomed Pharma Aktiengesellschaft
    Inventors: Karl Schermanz, Gerald Saischek, Dietmar Kores, Josef Graf, Gerhard Haas, Kurt Martetschlager