Abstract: A method of producing a graphene film (22) includes forming a catalyst film (20) on a support (18); forming a graphene film (22) on the catalyst film (20); and electrolytically removing the catalyst film (20) from the support (18). The method may include transferring the graphene film (22) to a substrate (29). A supported graphene film includes a conductive support (18); a catalyst film (20) formed on the conductive support (18) having a thickness in a range of 1 nm to 10 ?m, and a graphene film (22) formed on the catalyst film (20).

Abstract: FSP27 compositions and methods for treating cardiovascular diseases are described.

Abstract: A force-absorbing barrier 10 includes a plurality of concentric chambers 21, 23, 25 and 27 at least partially filled with fluid 42. The walls 22, 24, 26 and 28 defining the chambers are flexible. Fluid passages 30 in the interior walls 24, 26 and 28 between chambers allow fluid flow between the chambers. The fluid flow from chamber to chamber will absorb energy from the impact a motor vehicle, preventing the vehicle from impacting the terminal of a guardrail.

Abstract: Glucose deprivation is an attractive strategy in cancer research and treatment. Cancer cells upregulate glucose uptake and metabolism for maintaining accelerated growth and proliferation rates. Specifically blocking these processes is likely to provide new insights to the role of glucose transport and metabolism in tumorigenesis, as well as in apoptosis. As solid tumors outgrow the surrounding vasculature, they encounter microenvironments with a limited supply of nutrients leading to a glucose deprived environment in some regions of the tumor. Cancer cells living in the glucose deprived environment undergo changes to prevent glucose deprivation-induced apoptosis. Knowing how cancer cells evade apoptosis induction is also likely to yield valuable information and knowledge of how to overcome the resistance to apoptosis induction in cancer cells.

Abstract: Compositions and methods for the inhibiting tau phosphorylation, and treating or preventing neurodegenerative diseases, utilizing a tR1 peptide having the amino acid sequence of NVKSKIGSTENLK [SEQ ID NO: 1], or a variant thereof, are described.

Abstract: Devices, circuits, and methods for fabricating circuits. A device having ambipolar characteristics includes a semiconductor layer and multiple gates, a source contact, and a drain contact coupled to the semiconductor layer. One channel may have elections as the majority charge carrier and may be formed proximate to one of the gates. Another channel may have holes as the majority charge carrier and be formed proximate another gate. Each of the channels is generally parallel to the other and couples the source contact to the drain contact. The device may be optimized by adjusting the work-functions in one or more of source and drain contacts or gates to compensate for differences in the effective masses of the majority carriers in each of the channels. The ambipolar nature of the devices allows logic circuits to be fabricated using one or two of the devices.

Abstract: Compositions and methods for the inhibiting human growth hormone (hGH), and treating or preventing hGH-mediated disorders, using a S1H peptide having the amino acid sequence of [SEQ ID NO: 1], or a variant thereof, are described.

Abstract: A composite is formed from a combination of a polymer and pulverized coal and optionally a compatibilizing agent. The coal forms from about 10 to about 80% of the composite. The composite is form by blending the pulverized coal with the polymer to form the composite.

Abstract: Cables including conductors formed form ultra-conductive copper wires which have a lower temperature coefficient of resistance are disclosed. Methods of making the cables including conductors with ultra-conductive copper wires are further disclosed.

Abstract: A fluid processing system and method of processing a fluid includes a tank having an outer wall, a heating element, and an insulating element. The heating element is situated within the tank and includes a first electrode and a second electrode. The insulating element is positioned between the first electrode and the second electrode. As such, powering the heating element directs an electric current through the fluid within the tank for heating the fluid, while the insulating element provides electrical and thermal insulation to the outer wall of the tank.

Abstract: A single element antenna with the ability to have pattern control by placing multiple feeds on opposite ends of the antenna element and controlling the amplitude and phase distribution of each of the feed ports.

Abstract: A passive variable negative stiffness device (passive VNSD) configured to facilitate a transition to zero stiffness by using elastic devices (e.g., springs) combined with translating and rotating components. An exemplary embodiment of a passive VNSD may comprise at least one pretensioned and/or precompressed elastic device to produce the desired force-displacement profiles. For instance, an exemplary embodiment of a passive VNSD may be adapted to produce force-displacement profiles that transition from zero stiffness, to negative stiffness, and then to positive stiffness (ZNP) and from zero stiffness, to negative stiffness, and then back to zero stiffness (ZNZ).

Abstract: Stable monomeric phosphaplatins, namely, (pyrophosphato)platinum(II) or platinum(IV) complexes containing a cis-cyclohexanediamine ligand or enantiomerically enriched or enantiopure trans-cyclohexanediamine ligands, and synthesis of these complexes, are provided. Efficacies and toxicities of the phosphaplatin compounds are determined toward a variety of cancers, including sensitive and resistant ovarian cancers, head and neck, and colon cancers. Compositions comprising the platinum complexes, and methods for treatment of proliferative diseases or disorders by means of the complexes or the compositions comprising them are disclosed.

Abstract: An electrochemical cell 10 is provided that includes first and second electrodes 13, 15, an electrolyte medium 17 in electrolytic communication with the first and second electrodes 13, 15, a chemical substance capable of undergoing an electrochemical reaction, and a voltage source 19 in electrolytic communication with the first and second electrodes 13, 15. The first electrode 13 includes a layer of an active catalyst material 25, and graphene coating 27 at least partially covering the layer of the active catalyst material 25. Methods for making and using the graphene coated electrode are further provided.

Abstract: Parametric model based computer implemented methods for determining the stiffness of a bone and systems for estimating the stiffness of a bone in vivo. The computer implemented methods include determining a complex compliance frequency response function Y(f) and an associated complex stiffness frequency response function H(f) and independently fitting a parametric mathematical model to Y(f) and to H(f). The systems include a device for measuring the stiffness of the bone in vivo and a data analyzer to determine a complex compliance frequency response function Y(f) and an associated complex stiffness frequency response function H(f).

Abstract: Devices and methods for determining a propensity to diabetic and/or macular degeneration in a subject by measuring certain featured from a captured retinal image from a subject are described.

Abstract: FSP27 compositions and methods for treating cancers are described.

Abstract: Methods and FSP27 compositions for treating and/or preventing metabolic disease and conditions associated insulin resistance, obesity, inflammation and dyslipidemia are described.

Abstract: Methods of patient-specific modeling of the mechanical properties of bone and related systems. The methods include obtaining a bending stiffness (K) of a bone specimen non-invasively and non-destructively in a dynamic 3-point bending test, creating a mathematical mechanical model of the bone specimen, assigning an elastic modulus (E) to the bone specimen of the mathematical mechanical model, determining the flexural rigidity of the bone specimen from simulating the mathematical mechanical model, determining a discrepancy between the flexural rigidity of the bone specimen from the simulated mechanical model and based on the obtained K, adjusting the elastic modulus of the simulated mechanical model to minimize the discrepancy, adjusting the elastic modulus until an optimized elastic modulus is determined where the discrepancy is reduced below a predetermined threshold, and applying the optimized elastic modulus to the simulated mechanical model to determine a strength of the bone.

Abstract: Compounds that inhibit or reduce glucose transport and methods of using the compounds to treat cancer are provided herein.