Abstract: The invention provides, in various embodiments, polypeptides (e.g., camelid antibodies and antigen binding fragments thereof) that specifically bind to Spike glycoprotein of severe acute respiratory syndrome coronavirus (e.g., SARS-CoV-2-Spike). The invention also provides, in various embodiments, fusion proteins comprising one or more of the polypeptides, polynucleotides encoding the polypeptides, vectors and host cells suitable for expressing the polypeptides, and methods for treating viral infections (e.g., COVID-19).

Abstract: An expandable device includes a base having a top side and a bottom side, an expanding mechanism operably coupled to the base, and a button. The bottom side of the base is adapted to engage a portion of a portable electronic device. The button has a top side and a bottom side and is operably coupled to the expanding mechanism. The expanding mechanism is selectively movable between a first configuration whereby the button is disposed in a first, collapsed configuration and a second configuration whereby the button is disposed in a second, expanded configuration. Upon urging the button to the first configuration, the expandable device retains the button in the first configuration, and upon further urging the button towards the base, the button is released from the first configuration and moves to the second configuration.

Abstract: The present invention relates to compounds, compositions, and methods for brightening skin. The compounds, compositions, and methods of the present invention generally involve compounds produced by a Malassezia yeast, and chemical analogs thereof. In addition to skin brightening applications, the compounds, compositions, and methods of the present invention may be used to modulate melanocyte activity, induce melanocyte apoptosis, agonize an arylhydrocarbon receptor (AhR), improve hyperpigmentation caused by a hyperpigmentation disorder, and modulate melanin production, melanosome biogenesis, and melanosome transfer.

Abstract: A computing device displays a user interface for a data preparation application, including a flow pane that visually represents a data preparation flow and a plurality of icons in a flow element palette. Using a feature/version matrix, the device determines that (i) a first subset of parameterized operations represented by a first subset of icons is not supported by the data preparation server application according to a version number of the data preparation server application and (ii) a second subset of parameterized operations represented by a second subset of icons is supported by the data preparation server application. The device provides a first indication that the parameterized operations represented by the icons in the first subset are unavailable to be inserted into the data preparation flow and displays a visual indication that each of the icons in the second subset is available to be inserted.

Abstract: A system includes an optical source configured to emit a pulsed light beam, the optical source comprising one or more chambers, each of the one or more chambers configured to hold a gaseous gain medium, the gaseous gain medium being associated with an assumed gas life; at least one detection module configured to: receive and analyze data related to the pulsed light beam, and produce a beam quality metric based on the data related to the pulsed light beam; and a monitoring module configured to: analyze the beam quality metric, determine a health status of the gaseous gain medium based on the analysis of the beam quality metric, and produce a status signal based on the determined health status, the status signal indicating whether to extend use of the gaseous gain medium beyond the assumed gas life or to end use of the gaseous gain medium.

Abstract: An electronic lock, including: a power storage device; and photovoltaic cells located on a surface of the electronic lock, the photovoltaic cells being electrically coupled to the power storage device in order to provide a charging current to the power storage device.

Abstract: A docking accessory adapted to couple to a platform of a mobile electronic device. The docking accessory includes a docking connector portion comprising a first magnetic element configured to detachably attach to a second docking connector portion of the platform, wherein the second docking connector portion comprises a second magnetic element. The docking accessory further includes an accordion forming a tapered shape capable of extending outward from the platform generally along its axis to achieve an extended position, and retracting back toward the platform by collapsing generally along its axis to achieve a collapsed position, as well as a foot disposed at the distal end of the accordion. The docking accessory is operable as a stand for the platform and mobile electronic device when the docking accessory is in the extended position.

Abstract: A wheeled luggage case comprises (a) a storage chamber, (b) a cover defining an opening on at least one side of the storage chamber for providing ready access therein and at least two labyrinth axle-free wheels operatively connected to the chamber for towing the case along a ground surface. The labyrinth axle-free wheel comprises an internal rim, an external rim provided with a ground interface, rollers being rotatably disposed within a roller spacer between the internal and external rims in a uniform circumferential manner by means of a spacer and external covers. A labyrinth type dust passage in the wheel is defined by the rims and the external plates mechanically connected to the internal rim.

Abstract: Methods, systems, and computer readable medium include receiving, from a user device, a request for a digital component, receiving a data set of user-provided information regarding a particular product design, generating, based on the data set, a visual representation mapping design factors to potential product design geometry, segmenting the visual representation based on the design factor values, selecting a segment that contains less than a threshold amount of data points, selecting a digital component, dynamically altering, based on the selected segment, a presentation of the digital component that solicits information from the user about the segment, distributing, for presentation at the user device, the dynamically-altered digital component, obtaining, from the user device through a feedback mechanism, feedback information regarding the segment that contains less than the threshold amount of data points, and modifying a design factor of the particular product design based, at least in part, on the feedb

Abstract: Exemplary air amplifiers described herein can utilize a high-pressure stream of gas to accelerate a low-velocity stream of gas to provide a high-velocity, high-volume stream of gas. This high-velocity, high-volume stream of gas can generate unwanted noise as the high-velocity, high-volume stream of gas propagates through the air amplifier. The exemplary air amplifiers described herein can passively and/or actively suppress, for example, diminish, re-tune, or even completely cancel, the unwanted noise as the high-velocity, high-volume stream of gas propagates through these exemplary air amplifiers. The exemplary air amplifiers described herein can include one or more absorption materials to passively suppress the unwanted noise generated by the high-velocity, high-volume stream of gas. The exemplary air amplifiers described herein can generate multiple noise suppression waves to actively suppress the unwanted noise generated by the high-velocity, high-volume stream of gas.

Abstract: Disclosed are methods, systems and non-transitory computer readable memory for free-space optical (FSO) communications. For instance, a communications network may include FSO optical transceiver terminals located at remote electrically unpowered locations within the communications network. A remote unpowered FSO terminal located at a far-end location receives necessary optical power from a powered base station location (near-end) required for all optical amplification functions for NRZ or RZ format signals within the spectral range of 900 nm to 1480 nm as well as an Ultra Short Pulsed Laser (USPL) centered at 1560 nm at the far-end location. A transmitting node transmits an optical signal identified as a pump signal to a remote location over a free space medium, such as the atmosphere, where the remote location does not have available electrical power for operation of electro-optic components required for transmission and retransmission functions.

Abstract: Disclosed is an aqueous adhesive composition which comprises an admixture of: (a) a first aqueous composition comprising, (i) one or more film forming polymers, (ii) one or more lower crystallinity polynitroso compounds, (iii) one or more higher crystallinity polynitroso compounds, and (iv) one or more bismaleimide-containing monomers; and (b) a second aqueous composition comprising (i) an aqueous dispersion of at least one phenolic resin which is a condensation product of a phenol and formaldehyde, wherein the aqueous dispersion is stabilized by at least one polyacrylate; (b) one or more latices formed from one or more halogenated polyolefins; and (c) one or more metal oxides.

Abstract: A gun stand includes a support post, a tray assembly and a ground stake. A first telescoping connection connects the tray assembly to a first end of the support post. A second telescoping connection connects the ground stake to a second end of the support post. The two telescoping connections are independently adjustable.

Abstract: Systems and methods for connecting datasets are disclosed. For example, a system may include a memory unit storing instructions and a processor configured to execute the instructions to perform operations. The operations may include receiving a plurality of datasets and a request to identify a cluster of connected datasets among the received plurality of datasets. The operations may include selecting a dataset. In some embodiments, the operations include identifying a data schema of the selected dataset and determining a statistical metric of the selected dataset. The operations may include identifying foreign key scores. The operations may include generating a plurality of edges between the datasets based on the foreign key scores, the data schema, and the statistical metric. The operations may include segmenting and returning datasets based on the plurality of edges.

Abstract: Systems and methods are provided for a valve shut-off system of a medical device. In one embodiment, the valve shut-off system of the medical device includes a first pin movable between a first position where a valve is opened and a second position where the valve is closed, the first pin including a slot, and a second pin having a mating geometry with the slot of the first pin, the second pin adjustable between a locked position that holds the first pin in the first position and an unlocked position that enables movement of the first pin between the first position and the second position.

Abstract: Methods, systems, and media for transferring playback of media content are provided.