Abstract: An electronic smoking article includes a heater in communication with a liquid supply reservoir including liquid material and operable to heat the liquid material to a temperature sufficient to volatilize the liquid material contained therein and form an aerosol. The volatilized material flows through a sheath flow and aerosol promoter insert that is operable to cool the aerosol, reduce the particle size of the aerosol and increase the delivery rate of the aerosol.

Abstract: This disclosure relates to administration of a combination of: 1) about 100-110 mg, about 104-106 mg, or about 105 mg of bupropion hydrochloride, or a molar equivalent amount of a free base form or another salt form of bupropion; and 2) about 40-50 mg, about 44-46 mg, or about 45 mg of dextromethorphan hydrobromide, or a molar equivalent amount of a free base form or another salt form of dextromethorphan in certain patient populations, such as patients having moderate renal impairment, patients having mild or moderate hepatic impairment, patients receiving a concomitant strong CYP2D6 inhibitor, patients who are known CYP2D6 poor metabolizers, those in need of an NMDA antagonist that does not cause dissociation, and those at risk of QT prolongation.

Abstract: A computing system that can receive an object search request from a user indicating a request to search for a specific object in an area traversed by one or more autonomous vehicle. The object search request can include a set of physical characteristics of the specific object. The computing system can then transmit a signal to an autonomous vehicle indicating a request for the autonomous vehicle to search for the specific object. The signal can cause the autonomous vehicle to transmit an image, selected based on a physical characteristic of the object, to the computing system. The computing system can then generate a score indicative of a difference between one or more physical characteristic of the object in the image and the specific object. The computing system can then selectively transmit the image to a mobile device operated by the user based on the score.

Abstract: The invention relates to systems and methods for sensing fluid characteristics of peritoneal dialysate infused into and removed from a patient during treatment. The systems and methods include sensors, processors, and flow paths for determining patient health based on the fluid characteristics of the peritoneal dialysate. The system can be a peritoneal dialysis cycler which can include an infusion line; an effluent line; at least one pump positioned in the infusion and/or effluent line; and at least one sensor fluidly connected to the effluent line. The sensor can be at least one of a flow sensor, an ion selective electrode, a pH sensor, a pressure sensor, a refractive index sensor, and a temperature sensor. The method can include infusing peritoneal dialysate through an infusion line; removing peritoneal dialysate through an effluent line; and determining at least one fluid characteristic of the peritoneal dialysate in the effluent line.

Abstract: Various embodiments of the inventive cycle-mountable cargo retention apparatus may feature: a cargo cradle having a cradle longitudinal axis, a spine that defines a spine plane, and cargo support fastener holes established at respective non-zero cargo support fastener hole distances from the spine plane; and a cargo support that is removably fastenable to the cargo cradle with fasteners, where such fasteners, when the cargo support is fastened to the cargo cradle, define fastener centerlines that lie in an installed cargo support fastener plane that is perpendicular to the cradle longitudinal axis.

Abstract: A mobility management entity (MME) receives, from a first base station, a request for a handover of a wireless device to a second base station. Based on the handover request, the MME sends, to an access and mobility management function (AMF), an indication of an authentication and/or authorization (AA) status for an aerial service of the wireless device.

Abstract: A display device according to the present technology includes: a plurality of linear portions that, when three directions orthogonal to each other are a first direction, a second direction, and a third direction, extends in the first direction and is positioned apart from each other in the second direction; and a connecting portion that connects respective parts of two linear portions adjacent to each other in the second direction. The linear portion and the connecting portion are integrally formed by injection molding, the linear portion has a base extending in the first direction and a pair of protrusions protruding in the third direction from both end portions of the base in the second direction, and both end portions of the connecting portion are continuous to respective tip portions of the protrusions of the two adjacent linear portions.

Abstract: Disclosed herein are methods for training and deploying a predictive model for generating a prediction, e.g., patient eligibility for a CAR-T therapy. Datasets, such as open healthcare claims datasets, may be missing data. Missing data may hamper the ability to generate sufficient information needed for training a predictive model. Methods include leveraging comprehensive datasets, such as closed claims datasets, to create training examples for input into a machine learning algorithm. In various embodiments, the comprehensive dataset is modified to simulate the data missingness in the target dataset; then, the modified dataset is paired with the ground truth label derived from the comprehensive dataset to create training examples. In various embodiments, a comprehensive dataset is paired with a target dataset to create training examples. After training a predictive model on such examples, the model can be deployed to make predictions in the target dataset even in light of missing data.

Abstract: Aspects described herein may relate to a transaction exchange platform using a streaming data platform (SDP) and microservices to process transactions according to review and approval workflows. The transaction exchange platform may receive transactions from origination sources, which may be added to the SDP as transaction objects. As the transactions are processed, the transactions may require access to a resource (e.g., a key value in a database). A microservice processing the transaction may request, from a locking microservice, a lock for the resource. The locking microservice may query a local cache to determine whether a lock exists for the resource. If the local cache determines that no lock exists for resource, the locking mechanism may employ a consensus protocol to obtain a lock for the resource from a plurality of clusters. If consensus is reached, a lock for the resource may be granted to the requesting microservice.

Abstract: An oral tobacco product includes a body that is wholly receivable in an oral cavity. The body includes a mouth-stable polymer matrix and tobacco fibers embedded in the mouth-stable polymer matrix. The oral tobacco product can be formed by extruding a mixture of mouth-stable polymer and tobacco fibers.

Abstract: Systems, methods, and computer program products to transmit, by a web browser to a web server, a hypertext transfer protocol request for a web page at a first uniform resource identifier (URI). The web browser may receive, from the web server via, the web page and metadata of a plurality of candidate advertisements, the plurality of candidate advertisements determined based on a master machine learning (ML) model. A client ML model executing in the web browser may process the received metadata, the client ML model trained based on prior interactions between one or more users of the web browser and a plurality of previously displayed advertisements. The client ML model may determine based on the processing, a first candidate advertisement of the plurality of candidate advertisements to display in the web browser with the received web page.

Abstract: A method comprising receiving message content at a sending device. A location input is also received at the sending device, the location input identifying a geographic location. Using at least one processor, a location-based message is generated using the message content and the location input. A message marker is displayed, on a receiving map interface displayed on a display of a receiving device, at the geographic location identified by the location input.

Abstract: A system and apparatus for sanitizing person use items. The system is comprised essentially of a mechanism for emitting sanitizing electromagnetic radiation within an enclosed compartment. The apparatus may be light-tight such that the radiation is contained within the apparatus. It may be configured to emit a plurality of sanitizing wavelengths. The apparatus may include a series of reflective and/or refractive apparatuses to alter the reflection path of the emitted electromagnetic radiation, allowing the electromagnetic radiation to reflect in a plurality of directions. The enclosure may include a support member or personal item support that may be transparent to, or reflective of, the electromagnetic radiation.

Abstract: In some example, a hub receives a notification of activity from a particular sensor node of a plurality of sensor nodes that are monitoring an area. The notification includes sensor data including: a difference in decibels between a first volume of a first filtered audio and a second volume of a second filtered audio and at least a portion of the second filtered audio. The hub performs an analysis of the sensor data using an artificial intelligence algorithm. The hub determines, based on the analysis, a presence of one or more tunneling activities and sends, by a communications interface of the hub, a message indicating the presence of the one or more tunneling activities to a computing device.

Abstract: A dental medicament applicator is disclosed. In one embodiment, a placement device is sized for insertion at a dental site, such as an interproximal site. The placement device includes a central body and at least one active matrix secured to the central body containing a topical substance, such as a fluoride-containing chemical agent, silver diamine fluoride, or a peptide-based chemical agent, for example. One or two wings extend from the central body to provide subterminal opposition surfaces to hold the placement device during placement. The one or more wings are free of the topical substance. The active matrix, in response to being physically affixed to the dental site, delivers the topical substance at a controlled rate to the dental site while the placement device dissolves at a quicker controlled rate.

Abstract: Systems and methods are provided for automated detection and disinfection of microbes in autonomous vehicles, to prevent possible transmission of diseases or illness to subsequent users. Automated detection and disinfection of a vehicle includes autonomously scanning various parts of the autonomous vehicle for microbes, selecting a disinfectant based on detected microbes, and autonomously disinfecting at least a portion of the autonomous vehicle.

Abstract: A system includes: an inverter including: a first galvanic interface to separate a first high voltage area from a low voltage area; a first low voltage controller in the low voltage area, the first low voltage controller configured to send a first control signal using the first galvanic interface to a first high voltage controller in the first high voltage area; a second galvanic interface to separate a second high voltage area from the low voltage area; and a second low voltage controller in the low voltage area, the first low voltage controller configured to send a second control signal using the second galvanic interface to a second high voltage controller in the second high voltage area, wherein the second low voltage controller is configured to provide an output latch signal to the first low voltage controller and receive an input latch signal from the first low voltage controller.

Abstract: Disclosed herein is digital object generator that makes uses a one-way function to generate unique extended reality environments based on the user specific input. Features of the input are first extracted via a few-shot convolutional neural network model, then evaluated weight and integrated fit. The resulting digital object includes a user decipherable output such as a visual representation, an audio representation, or a multimedia representation that includes recognizable elements from the user specific input.