Abstract: A method for optimal selection of cytotoxic agents for organ or region specific therapy that includes extracorporeal filtration of the cytotoxic agent from blood drained from the organ or region being treated and return of the filtered blood to a mammal is disclosed.

Abstract: A connector-equipped case that includes a case that includes a through hole; a connector fixed to the case, the connector including: a core that supports a plurality of terminals; and a hood that is formed by forming a region around the through hole of the case and a portion of the core in one piece; and an adhesive layer that is interposed between the case and the hood, wherein a constituent material of the adhesive layer is an adhesive that contains acrylic rubber.

Abstract: The present disclosure is directed to a computerized method, system and software application for coordinating medical care through a Pathways Community Hub (HUB). A Pathways Community Hub is a network of care coordination agencies which focuses its mission towards reaching individuals within the community having the greatest risk-factors through the deployment of service providers such as community care coordinators. The Pathways Community Hub finds at-risk individuals in need of medical, health-related or social services, treats identified risk factors and measures a patient's risk status over time. The goal of the Pathways Community Hub is to achieve a reduction of risk among patients through open communication and collaboration among service providers including medical service providers and community-based organizations and to reduce the overall cost of medical, health-related and social services over time within a region.

Abstract: In one embodiment, a distributed antenna system comprises at least one master unit; at least one remote antenna unit coupled to the master unit and comprising a power amplifier to radiate a remote downlink radio frequency signal, the remote antenna unit further configured to receive a remote uplink radio frequency signal from at least one antenna, the remote downlink radio frequency signal comprises first and second downlink frequency bands and wherein the remote uplink radio frequency signal comprises first and second uplink frequency bands; a band suppression module comprising: a controller; an uplink band suppression element configured to apply an attenuation to suppress the first uplink frequency band in response to a signal from the controller; and a downlink band suppression element configured to apply an attenuation to suppress the first downlink frequency band in response to the signal from the band suppression controller.

Abstract: A method and apparatus for the rapid and reliable preparation of a sample for use in testing for target analytes such as bacteria, viruses, toxins and pathogenic agents in various products. A sample for testing the target analyte is collected from various sources. The method for sample preparation provides for an express process for preparing collected samples for testing. The collected sample may be concentrated by centrifugation, filtration, or other means suitable for sample concentration, homogenized with the addition of a broth and enriched for specified period of time. Immunomagnetic separation of the sample occurs with receptor-coated magnetic microspheres in different test-specific formulations (singleplex or multiplex). An automatic testing system is disclosed which includes a biological testing cassette, in which testing of the sample occurs using liquid crystal diagnostic methodologies.

Abstract: A connector-equipped case that includes a case that includes a through hole; a connector fixed to the case, the connector including: a core that supports a plurality of terminals; and a hood that is formed by forming a region around the through hole of the case and a portion of the core in one piece; and an adhesive layer that is interposed between the case and the hood, wherein a constituent material of the adhesive layer is an adhesive containing non-diene-based rubber and an amino silane coupling agent.

Abstract: An electron microscope (EM) preparation and imaging system including an EM device and a sample preparation device for forming a vitreous ice layer containing a liquid sample through vitrification, which are located within a sealable environment. The sample preparation apparatus includes a cryogenically-cooled stage that receives a sample deposit surface, such as a cryo-EM grid, which is cryogenically cooled through direct contact with the stage. A sample dispenser is movable with respect to the stage and is configured to deposit a liquid sample onto the sample deposit surface at a selected rate of deposition. Once the liquid sample is deposited onto the sample deposit surface by the sample dispenser, it is vitrified automatically in place.

Abstract: An encapsulation system (100) for use in securing a rock bolt in a bore hole drilled into a rock face to be stabilised, said encapsulation system comprising at least two separate encapsulation mediums (112,122) and one or more elongate cartridges (110,120) containing said encapsulation mediums (112,122), each said cartridge having a frangible casing (111,121), said encapsulation mediums including: a first encapsulation medium (112) comprising a curable first resin formulation; and a second encapsulation medium (122); wherein, following use in securing a rock bolt, said second encapsulation medium has a lower bond strength and/or a lower compressive strength than said first resin formulation.

Abstract: A squirrel-cage induction rotating electrical machine comprises: a solid rotor, a stator, and bearings. The solid rotor includes a shaft part, a columnar-shaped rotor core part integrally formed with the shaft part and having rotor slots formed therein, and a plurality of conductor bars passing through the respective rotor slots and coupled together at both axial ends outside the rotor core part. The stator includes a cylindrical stator core provided radially outside the rotor core part, and stator windings passing through a plurality of respective stator slots which are formed in the radially inner surface of the stator core. An outer wall and an inner wall of each rotor slot are tilted at a predetermined angle or more with respect to a plane including a rotation axis of the shaft part.

Abstract: The invention relates to a belt deflector with a main element (100) that can be attached to the structure of a vehicle, and with a belt support element (200) that is movable relative to the main element (100) and forms a support surface (231) or support edge for a safety belt (20) to be deflected. According to the invention, the belt deflector comprises an intermediate element (300, 400) that is deformed when the movable belt support element (200) is moved relative to the main element (100), in the direction of the intermediate element (300, 400), and because of this deformation is pressed against the safety belt (20).

Abstract: A memory device includes a memory stack formed on a substrate to program skyrmions within at least one layer of the stack. The skyrmions represent logic states of the memory device. The memory stack further includes a top and bottom electrode to receive electrical current from an external source and to provide the electrical current to the memory stack. A free layer stores a logic state of the skyrmions in response to the electrical current. A Dzyaloshinskii-Moriya (DM) Interaction (DMI) layer in contact with the free layer induces skyrmions in the free layer. A tunnel barrier is interactive with the DMI layer to facilitate detection of the logic state of the skyrmions in response to a read current. At least one fixed magnetic (FM) layer is positioned within the memory stack to facilitate programming of the skyrmions within the free layer in response to the electrical current.

Abstract: Disclosed are various embodiments for reinforcement learning-based irrigation control to maintain or increase a crop yield or reduce water use. A computing device may be configured to determine an optimal irrigation schedule for a crop planted in a field by applying reinforcement learning (RL), where, for a given state of a total soil moisture, the computing device performs an action, the action comprising waiting or irrigating crop. An immediate reward may be assigned to a state-action pair, the state-action pair comprising the given state of the total soil moisture and the action performed. The computing device may instruct an irrigation system to apply irrigation to at least one crop in accordance with the optimal irrigation schedule determined, where the optimal irrigation schedule includes an amount of water to be applied at a predetermined time.

Abstract: Systems and methods for point-of-care determination of blood potassium are provided. The approaches are based on the reaction of ADP and PEP in the presence of potassium ion and pyruvate kinase to produce pyruvate and ATP. In one method, the produced pyruvate is reacted with phosphate and mediator, in the presence of pyruvate oxidase, to yield acetylphosphate and reduced mediator, and the reduced mediator is used to determine the blood potassium using conventional electrochemical methods. In an alternative method, the produced pyruvate is reacted with phosphate and oxygen in the presence of pyruvate oxidase to yield acetylphosphate and hydrogen peroxide, and the hydrogen peroxide is measured optically in accordance with known methods.

Abstract: In some aspects, there is provided a method for determining a rotational orientation of an object in an image. The image depicts the object in a scene. The method includes providing images depicting the object in the scene to a trained statistical model. The images depict the scene of the image at different rotation angles. A rotation angle of a respective image corresponds to a potential rotational orientation of the object depicted in the respective image. The method further includes, in response to the providing, receiving, for each image, a confidence score indicating a likelihood generated by the trained statistical model that the object is at the potential rotational orientation corresponding to the rotation angle of the respective image. The method further includes determining the rotational orientation of the object in the image based at least in part on an analysis of the confidence scores and respective potential rotational orientations.

Abstract: Vaccine compositions including a yeast comprising an immunostimulatory polypeptide and optionally an antigenic polypeptide are provided herein. The immunostimulatory polypeptide and the antigenic polypeptide are expressed or displayed on the surface of the yeast vaccine composition. Methods of using the vaccine composition to vaccinate subjects are also provided.

Abstract: A seal member that includes an insertion hole into which a connector terminal is insertable, wherein, when a direction in which the connector terminal is to be inserted into the insertion hole is defined as an insertion axis: an inner diameter of a cross-section of the insertion hole orthogonal to the insertion axis at a position at which the inner diameter is the smallest is denoted as a minimum hole diameter D, an outer length of a cross-section of the connector terminal orthogonal to the insertion axis at a position at which the outer length is the largest is denoted as a maximum terminal outer length L, and the minimum hole diameter D and the maximum terminal outer length L satisfy a relationship 2.1?L/D?4.2.

Abstract: A connector-equipped case that includes a case that includes a through hole; and a connector fixed to the case, the connector including: a core that supports a plurality of terminals; and a hood that is formed by forming a region around the through hole of the case and a portion of the core in one piece, wherein a constituent material of the hood is a resin composition containing polybutylene terephthalate and polyethylene terephthalate.

Abstract: In an ultrasound automatic scanning system according to an embodiment, one or more ultrasound probes transmit and receive an ultrasound wave. A mechanical mechanism holds the ultrasound probe and moves the ultrasound probe while a surface of the ultrasound probe is directed toward a subject. Processing circuitry detects, based on the ultrasound wave, distance information between a body surface and the surface of the ultrasound probe, with respect to a first scan position and a second scan position set along the body surface. The processing circuitry controls ultrasound scans performed in the first scan position and in the second scan position by the ultrasound probe moved by the mechanical mechanism based on the distance information. The processing circuitry controls the mechanical mechanism so as to move the ultrasound probe to the second scan position after the distance information detection and the ultrasound scan in the first scan position are performed.

Abstract: Methods of pyrolytically producing carbons comprising graphene sheets at temperatures below 800° C. are disclosed. The graphene sheets, which are not substantially stacked, are formed by templating on hexagonal metal oxides, for example. Extensive stacking of the graphene sheets, which would lead to formation of graphite, is avoided at the low temperatures employed. Also provided are methods of producing heavily nitrogen doped graphene comprising carbons. Methods of using graphene and heavily nitrogen doped graphene are also disclosed.

Abstract: The invention relates to a tester apparatus of the kind including a portable supporting structure for removably holding and testing a substrate carrying a microelectronic circuit. An interface on the stationary structure is connected to the first interface when the portable structure is held by the stationary structure and is disconnected from the first interface when the portable supporting structure is removed from the stationary structure. An electrical tester is connected through the interfaces so that signals may be transmitted between the electrical tester and the microelectronic circuit to test the microelectronic circuit.