Abstract: Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2?3-cGAMP, 2?2-cGAMP, 3?2?-cGAMP and 3?3?-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics.

Abstract: The present invention relates to control of wind turbines where a noise measure is taken into account. Control of a wind turbine is described where a control trajectory is calculated based on noise measure, the noise measure being determined from a predicted operational trajectory. In embodiments the predicted operational trajectories are calculated by using a model predictive control (MPC) routine.

Abstract: A data storage system includes a generic snapshot interface, allowing for integration with a wide variety of snapshot-capable storage devices. The generic interface can be a programming interface (e.g., an application programming interface [API]). Using the snapshot interface, storage device vendors can integrate their particular snapshot technology with the data storage system. For instance, the data storage system can access a shared library of functions (e.g., a dynamically linked library [DLL]) provided by the vendor (or another by appropriate entity) and that complies with the specifications of the common programming interface. And by invoking the appropriate functions in the library, the data storage system implements the snapshot operation on the storage device.

Abstract: Some aspects of the disclosure generally relate to providing single sign on features in mobile applications in a secure environment using a shared vault. An application may prompt a user to provide user entropy such as a passcode (e.g. a password and/or PIN). The application may use the user entropy to decrypt a user-entropy-encrypted vault key. Once the vault key is decrypted, the application may decrypt a vault database of the shared vault. The shared vault may store shared secrets, such as server credentials, and an unlock key. The application may store the unlock key, generate an unlock-key-encrypted vault key, and cause the shared vault to store the unlock-key-encrypted vault key, thereby “unlocking” the vault. The application may then use the unlock key to decrypt the vault database without prompting the user to provide user entropy again.

Abstract: An exhaust gas cooler comprises at least one exhaust gas pipe for exhaust gas being cooled and is characterized in that at least one gap is provided between the wall of the exhaust gas pipe and laterally adjacent components at the inlet of at least one exhaust gas pipe in the direction of extension of at least one wall perpendicular to the flow direction of the exhaust gas.

Abstract: A heat source system that optimizes a load on compressors in multiple heat source machines with respective independent refrigeration cycles that are situated in series. This is accomplished by using an information acquisition unit that acquires measurement values of operation frequencies of compressors from the respective heat source machines, a load distribution change unit that changes a load distribution currently assigned to each of the heat source machines, and a temperature setting unit that sets the hot/chilled water outlet temperatures of respective heat source machines.

Abstract: A system and method for using an embedded microprocessor in an RF amplifier. The use of an embedded microprocessor avoids manual calibration. The Microprocessor collects initial amplifier performance data based on a set of parameters and calculates the needed corrections. The microprocessor can change levels within the circuit to achieve those operating points. The embedded microprocessor sets voltage levels with internal circuitry and communicates this information externally through a serial communication port, or the like, to allow a user to communicate with and look at the amplifier data and readjust the internal bias levels, as needed. Thus, the internal microprocessor provides for calibration, self-testing, and monitoring of the RF amplifier and also functions as an in situ bias and temperature compensation controller for use in the presence of temperature variation and provides bias sequencing control to protect against improper applied timing of voltage inputs to the amplifier.

Abstract: An anchor bolt fastener assembly with specialized connection capabilities and features for attaching building components to concrete slabs, walls, ceilings, and/or structural surfaces. Compression force can be established and maintained over time using a compression washer in combination with a specialized fastener stud that is designed to exploit the compression washer benefits. Methods of using exemplary embodiments include installing the anchor bolt fastener assembly relatively flush with the surface of the concrete slurry by direct insertion in the slurry using a specialized threaded anchor bolt float. Once the slurry hardens, the anchor bolt and anchor bolt float embedded in the concrete slurry cooperate with the specialized fastener stud to secure the building component to the concrete.

Abstract: Brake discs, systems, and methods may include a brake disc and a brake drum. In various embodiments, the brake disc includes a central hub, configured to engage with an axial shaft. The brake disc includes protrusions, each of which is coupled to the central hub and extends perpendicularly from the central hub. The brake disc includes expansion components, each of which is coupled to the central hub at two locations. Each expansion component surrounds an outer periphery of one of the protrusions. The expansion components define a segmented periphery configured as a braking surface. The brake drum is configured to have an inner diameter that is larger than an outer diameter of the brake disc. The outer diameter of the brake disc is defined by the segmented periphery, such that an inner surface of the brake drum is concentric around the segmented periphery of the brake disc.

Abstract: A method and apparatus for generating electricity by electromagnetic induction, using a magnetic field modulated by the formation, dissipation, and movement of vortices produced by a vortex material such as a type II superconductor. Magnetic field modulation occurs at the microscopic level, facilitating the production of high frequency electric power. Generator inductors are manufactured using microelectronic fabrication, in at least one dimension corresponding to the spacing of vortices. The vortex material fabrication method establishes the alignment of vortices and generator coils, permitting the electromagnetic induction of energy from many vortices into many coils simultaneously as a cumulative output of electricity. A thermoelectric cycle is used to convert heat energy into electricity.

Abstract: Example apparatus to communicatively couple three-wire field devices to controllers in a process control system are disclosed. An example terminal block is disclosed that includes a first interface including termination points to couple with a field device, a second interface to couple with a shared bus of a termination panel, wherein the shared bus is to remain coupled to a controller when the terminal block is removed, a third interface to couple with a power bus of the termination panel, and a fuse disposed between the first interface and the third interface.

Abstract: An ophthalmological laser treatment system comprising a laser source (2) for producing laser radiation, a light projector (3) for focusing the laser radiation onto a focus (F) and a scanner system (5) for moving the focus (F) along a work line (p) comprises a monitoring system (6), which comprises a light detector (60) and is configured to monitor, by way of a light path (r), a monitored region (m) moving together with the focus (F). The monitoring system (6) is configured to monitor a monitored region (m), which moves together with the focus (F) with a fixed geometric assignment to the focus (F) and is for example disposed upstream of the focus (F) in the work direction and not yet worked on by laser radiation.

Abstract: A vehicular positioning system utilizing multiple optical cameras having contiguous fields of view for reading coded markers having pre-determined positions for determining the position of vehicle inside a structure with a high degree of accuracy. The vehicle positioning system provides for the direct installation and use of a positioning apparatus on a vehicle with a limited number of coded markers to determine the vehicle's position to within millimeter level accuracy.

Abstract: A cooling member includes a fluid-tight sealed body that is formed by a first laminated sheet and a second laminated sheet being joined to each other at at least one joint portion, a coolant that is enclosed in the sealed body, and a heat dissipation plate that is joined in a fluid-tight manner to an inner surface of the sealed body at at least one joint portion and that has a heat absorption portion that is located inside the sealed body and a heat dissipation portion that is located outside the sealed body.

Abstract: We describe a wavelength division multiplexed (WDM) reconfigurable optical switch, the switch comprising: a set of arrays of optical beam connections, each comprising an array of optical outputs and having an optical input to receive a WDM input optical signal; a first diffractive element to demultiplexed said WDM input optical signal into a plurality of demultiplexed optical input beams, and to disperse said demultiplexed optical input beams spatially along a first axis; first relay optics between said set of arrays of optical beam connections and said first diffractive element; and a reconfigurable holographic array comprising a 2D array of reconfigurable sub-holograms defining sub-hologram rows and columns; wherein said arrays of said set of arrays are at least one dimensional arrays extending spatially in a direction parallel to said first axis and arranged in a column defining a second axis orthogonal to said first axis; wherein said sub-hologram rows are aligned along said first axis, and wherein said s

Abstract: A graphics verification system that handles content of a channel in a broadcast chain, partitions an on-screen view of the channel into a plurality of sections based on an overlay of a plurality of graphics on the on-screen view of the channel. The content may comprise media content and may include video, audio and/or ancillary data that is associated with any portion of a particular content. A placement of each of the overlaid plurality of graphics in the plurality of sections is determined with respect to associated content on the on-screen view of the channel. The placement is determined based on a concurrent look-up of the overlaid plurality of graphics in the plurality of sections and the associated content. The concurrent look-up is based on fingerprints or watermarks of the plurality of graphics and the associated content. One or more error parameters are detected based on the determined placement.

Abstract: A system for detecting the presence of an occupant of a seat. The system includes a sensing mat that includes an upper conducting layer and a lower conducting layer. At least one of the conducting layers comprises a printed electronic circuit separated into conductive zones by at least one resistive zone. The mat also includes a plurality of sensing zones and each of the sensing zones include a conductive zone from the upper conducting layer and a conductive zone from the lower conducting layer. Each of the conducting layers are connected to a controller configured to detect a change in capacitance of each of the sensing zones resulting from a change in distance between the upper conducting layer and the lower conducting layer. The controller is connected to a vehicle network and is configured to provide data to the network that indicates the absence or presence of the occupant.

Abstract: The specification is directed to an apparatus for combining laser beams having a same polarization. The apparatus includes a prism having a prism body and a plurality of surfaces, and a crystal coupled to the prism, the crystal having a crystal body and formed of a birefringent material. The prism is configured to receive two laser beams each having a same input linear polarization, totally internally reflect the first laser beam off one or more of the plurality of surfaces to change the linear polarization of the first beam to an orthogonal polarization, refract the second laser beam, and output the laser beams parallel to each other, and having orthogonal polarizations. The crystal is configured to receive the laser beams from the prism and combine them to form an orthogonally polarized combined laser beam.