Abstract: Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids.

Abstract: Systems, methods, and devices enable spectrum management by identifying, classifying, and cataloging signals of interest based on radio frequency measurements. In an embodiment, signals and the parameters of the signals may be identified and indications of available frequencies may be presented to a user. In another embodiment, the protocols of signals may also be identified. In a further embodiment, the modulation of signals, data types carried by the signals, and estimated signal origins may be identified.

Abstract: The scintillation detector assembly 10 comprises a first scintillation detector 11A of a set SSD of scintillation detectors 11, comprising a first scintillator 12A of a set SS of scintillators 12 and a first light sensor 13A of a set SLS of respective light sensors 13 optically coupled thereto, arranged to detect electromagnetic radiation and output a first signal; a first radiation source 14A of a set SRS of radiation sources 14, configured to emit first gamma radiation G1 of a first set SG of gamma radiation G, having a first reference energy RE1 of a set SRE of respective first reference energies RE; and a controller 15 configured to control a gain of the first scintillation detector 11A based, at least in part, on the first gamma radiation, having the first reference energy, detected by the first scintillation detector 11A.

Abstract: A method and system for generating a voxel-based quadratic penalty model for automatic intensity modulated radiation therapy (IMRT) treatment planning are disclosed herein. A computing system generates an initial assignment of threshold values to a penalty function for IMRT treatment planning. The computing system receives an update to a dose value associated with the IMRT treatment planning. The computing system dynamically updates the threshold values based on the updated dose value. The computing system continues to iterate the threshold values based on further updated dose values.

Abstract: A laser transmission apparatus utilizing multiple laser beams and beam paths with a diverger lens to provide an illumination pattern that can compensate for lateral movement of the platform during shearography is provided. Further, this optical setup requires no moving parts and does not reduce power of the laser beams as they move through the individual components thereof. From the perspective of the surface being scanned or inspected, the present disclosure may provide two laser images of a single surface that appear to be identical despite the fact that they were taken from two different spatial positions of the moving platform.

Abstract: A surgical device for suturing a body lumen is described, as well as methods for suturing tissue employing the surgical device. The device can include a body having a shaft and a foot for insertion into an opening in the body lumen. The device can include tissue ports between the shaft and the foot configured to receive tissue surrounding the opening in the body lumen. The foot can include a suture secured to needle capture devices. The device can include needles that can be advanced through tissue and into the needle capture devices. The needle capture devices can then be withdrawn, thereby harvesting the suture, which can then be used to close the opening in the body lumen.

Abstract: Various embodiments described herein relate to methods, apparatuses, and systems for recovering gas sensors from silicone poisoning. In an example embodiment, a method of recovering a gas sensing apparatus from silicone poisoning is provided. The method includes exposing the gas sensing apparatus to a predetermined hydrogen concentration for a period of hydrogen exposure time. The predetermined hydrogen concentration breaks down the silicon oxide bonds formed on a catalytic bead of the gas sensing apparatus. The method also includes providing a methane concentration to the gas sensing apparatus for a period of methane exposure time. The method further includes determining that the gas sensing apparatus satisfies a predetermined calibration sensitivity based on the reaction of the gas sensing apparatus to the methane concentration.

Abstract: A medical fluid storage and transportation enclosure can include a housing, a chamber, an exhaust duct, an inlet duct, and a valve. The housing can include walls defining a cavity, where the cavity can be configured to receive a medical product therein. The chamber can be adjacent to the cavity and can be configured to exchange heat with the cavity. The valve can be located in the inlet duct, where the valve can be movable in response to an air.

Abstract: In one embodiment, an EV charging system includes: a plurality of first converters to receive and convert grid power at a distribution grid voltage to at least one second voltage; a high frequency transformer coupled to the first converters to receive the at least one second voltage and output at least one high frequency AC voltage; and a plurality of port rectifiers coupled to a plurality of secondary windings of the high frequency transformer, each of the port rectifiers comprising a unidirectional AC-DC converter to receive and convert the at least one high frequency AC voltage to a DC voltage. At least some of the port rectifiers may be coupled in series to provide at least one of a charging current or a charging voltage to at least one dispenser to which at least one EV is to couple.

Abstract: An optical measurement unit for a scanning device, a scanning device, and a method for operating a scanning device, for high throughput sample analysis of biological samples are disclosed. An illumination system is used to emit light of at least two different illumination wavelength ranges, and an imaging system is used to detect light of at least two different detection wavelength ranges, in order to detect electromagnetic radiation within a field of view for determining the positioning of a sample within the field of view.

Abstract: A 3-D package structure for isolated power module is discussed. The package structure has metal trace in a support layer (e.g. a substrate board), which is covered by two magnetic films from both sides, thus an effective transformer is formed. An IC die which contains a voltage regulator is stacked above the support layer, which significantly reduces the package size.

Abstract: A storage assembly includes top and bottom walls, a pair of end walls extending between the top and bottom walls and cooperating with the top and bottom walls to define an interior space, and at least one end surface configured to closely interfit with at least one end surface of an adjacent storage assembly that is substantially similar to the storage assembly at a predefined angular orientation such that a longitudinal axis of the storage assembly is angularly offset from a longitudinal axis of the adjacent storage assembly when the at least one end surface of the storage assembly is interfit with the at least one surface of the adjacent storage assembly The storage assembly may also include a pair of interior walls and a handle relief extending into the top wall and/or a frame assembly located between one of the end walls and one of the interior walls.

Abstract: Systems, methods, and apparatuses for providing dynamic, prioritized spectrum utilization management. The system includes at least one monitoring sensor, at least one data analysis engine, at least one application, a semantic engine, a programmable rules and policy editor, a tip and cue server, and/or a control panel. The tip and cue server is operable utilize the environmental awareness from the data processed by the at least one data analysis engine in combination with additional information to create actionable data.

Abstract: The medical image processing apparatus according to the present embodiment includes processing circuitry. The processing circuitry is configured to acquire volume data generated based on tomosynthesis imaging of a subject. The processing circuitry is configured to set a virtual focal point at a position different from a focal position in the tomosynthesis imaging. The processing circuitry is configured to generate a pseudo projection image based on the virtual focal point and the volume data.

Abstract: Systems and methods for providing and/or facilitating live browsing of granular mail or mailbox data, such as data stored within Exchange mailboxes, are described. For example, the systems and methods may provide mechanisms for browsing and/or restoring granular data (e.g., email data) from an Exchange database backup copy (or other secondary copy), without having to restore the entire database from the backup copy.

Abstract: An LFP electrode material is provided which has improved impedance, power during cold cranking, rate capacity retention, charge transfer resistance over the current LFP based cathode materials. The electrode material comprises crystalline primary particles and secondary particles, where the primary particle is formed from a plate-shaped single-phase spheniscidite precursor and a lithium source. The LFP includes an LFP phase behavior where the LFP phase behavior includes an extended solid-solution range.

Abstract: An outer-ring lubrication groove pattern formed in an outer-race raceway surface and an inner-race lubrication groove pattern formed in an inner-race raceway surface of a wave generator bearing of a strain wave gearing device are patterns in which linear lubrication grooves having very small widths and depths of several micrometers or less are arranged at fine pitches of several micrometers or less. The inner-race lubrication groove pattern includes a second groove pattern formed in long-axis-side inner-race raceway surface portions to hold the lubricant, and a first groove pattern formed in short-axis-side inner-race raceway surface portions to hold the lubricant and guide the lubricant to the second groove pattern. This configuration improves the contact state between balls and the inner-race and outer-race raceway surfaces of the wave generator bearing, thus reducing the coefficient of friction therebetween.

Abstract: According to one embodiment, a converter array includes a first substrate, multiple sets of a plurality of analog-digital converters and a switch. The multiple sets are arranged on the first substrate in array. The switch is configured to switch a connection relationship between the plurality of analog-digital converters to process signals from photodiodes smaller in number than the analog-digital converters.

Abstract: One example may include a method that includes receiving, at a presentation server, an audio data signal from a mobile device located in a presentation space, identifying a mobile device identification characteristic of the mobile device based on the received audio data signal, determining a mobile device location via a location determination procedure, and playing the audio signal via a loudspeaker.

Abstract: Techniques are provided for phase coherent frequency synthesis. An embodiment includes a first phase accumulator to accumulate a frequency control word (FCW) at a clocked rate to produce a first digital phase signal representing phase data corresponding to phase points on a first sinusoidal waveform. The embodiment also includes a second phase accumulator to produce an incrementing reference count at the clocked rate and multiply it by the FCW to produce a second digital phase signal representing phase data corresponding to phase points on a second sinusoidal waveform. The multiplication is performed in response to change in the FCW. The embodiment further includes a multiplexer to select between the first and second digital phase signals based on completion of the multiplication. The embodiment also includes a phase-to-amplitude converter to generate digital amplitude data corresponding to the phase points on a sinusoidal waveform associated with the selected digital phase signal.