Patents Assigned to Optonol Ltd.
  • Patent number: 6558342
    Abstract: An implant having a tube for permitting fluid flow has an outer flange at the outlet end and a retention projection near the inlet end. A delivery device for implanting the implant has a central bore for accommodating the implant during the implantation procedure. When the implant is loaded in the delivery device, the retention projection of the implant protrudes beyond the outside surface of the delivery device. After the delivery device and implant have penetrated the tissue through which drainage is desired, and the retention projection has fully penetrated through the tissue, the delivery device is withdrawn. The retention projection acts as a hook engaging the inside surface of the tissue, causing the implant to stay implanted in the tissue. An implant may also be provided with a mechanism for temporary occlusion, in whole or in part, of the flow passage.
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: May 6, 2003
    Assignee: Optonol Ltd.
    Inventors: Ira Yaron, Orit Yarden
  • Patent number: 6510600
    Abstract: An implant includes a tube for permitting fluid flow. A flow controlling rod may be inserted within the tube passage. One or more holes around the circumference of the tube may be selectively permanently or temporarily occluded to give desired flow characteristics. A delivery device for implanting the implant may include a central bore in which a retractable wire is located. The retractable wire penetrates a tube passage of the implant when the implant is attached to the delivery device. A hook on the delivery device prevents the implant from moving down the wire. After the implant is in position in the eye, the retention wire is retracted out of the implant. With the retention wire retracted, the implant is then free to slide away from the hook, allowing the delivery device to be withdrawn, leaving the implant in place. In a method for manufacturing an implant, two tubes of different diameters are utilized. The smaller tube fits inside the longitudinal bore of the larger tube.
    Type: Grant
    Filed: December 4, 2000
    Date of Patent: January 28, 2003
    Assignee: Optonol, Ltd.
    Inventors: Ira Yaron, Orit Yarden
  • Patent number: 6468283
    Abstract: An ophthalmic implant for treatment of glaucoma, a delivery device for implanting such an implant, and a method of implanting such an implant. The implant includes a tube having an inlet end, an outlet end, and a tube passage therebetween, and a disk connected to the tube at the outlet end of the tube. The tube passage has a cross-sectional area sufficiently small to inhibit the flow of aqueous humor through the tube passage. The implant provides a bleb of aqueous humor under the conjunctiva so that the bleb and the elasticity of the conjunctiva assist in regulating the flow of aqueous humor through the tube as a function of the IOP. The tube at its inlet end has a beveled surface facing away from the iris and one or more circumferential holes. One or more retention projections are provided for anchoring and may be extended outwardly when the implant is implanted in the eyeball. The disk has an outer rim and one or more inner uprights.
    Type: Grant
    Filed: August 26, 1999
    Date of Patent: October 22, 2002
    Assignee: Optonol, Ltd.
    Inventors: Jacob Richter, Gregory Pinchasik, Ira Yaron
  • Publication number: 20010000527
    Abstract: An implant includes a tube for permitting fluid flow. A flow controlling rod may be inserted within the tube passage. One or more holes around the circumference of the tube may be selectively permanently or temporarily occluded to give desired flow characteristics.
    Type: Application
    Filed: December 4, 2000
    Publication date: April 26, 2001
    Applicant: Optonol Ltd.
    Inventors: Ira Yaron, Orit Yarden
  • Patent number: 6203513
    Abstract: An implant includes a tube for permitting fluid flow. A flow controlling rod may be inserted within the tube passage. One or more holes around the circumference of the tube may be selectively permanently or temporarily occluded to give desired flow characteristics. A delivery device for implanting the implant may include a central bore in which a retractable wire is located. The retractable wire penetrates a tube passage of the implant when the implant is attached to the delivery device. A hook on the delivery device prevents the implant from moving down the wire. After the implant is in position in the eye, the retention wire is retracted out of the implant. With the retention wire retracted, the implant is then free to slide away from the hook, allowing the delivery device to be withdrawn, leaving the implant in place. In a method for manufacturing an implant, two tubes of different diameters are utilized. The smaller tube fits inside the longitudinal bore of the larger tube.
    Type: Grant
    Filed: November 20, 1997
    Date of Patent: March 20, 2001
    Assignee: Optonol Ltd.
    Inventors: Ira Yaron, Orit Yarden
  • Patent number: 5968058
    Abstract: An ophthalmic implant for treatment of glaucoma, a delivery device for implanting such an implant, and a method of implanting such an implant. The implant includes a tube having an inlet end, an outlet end, and a tube passage therebetween, and a disk connected to the tube at the outlet end of the tube. The tube passage has a cross-sectional area sufficiently small to inhibit the flow of aqueous humor through the tube passage. The implant provides a bleb of aqueous humor under the conjunctiva so that the bleb and the elasticity of the conjunctiva assist in regulating the flow of aqueous humor through the tube as a function of the IOP. The tube at its inlet end has a beveled surface facing away from the iris and one or more circumferential holes. One or more retention projections are provided for anchoring and may be extended outwardly when the implant is implanted in the eyeball. The disk has an outer rim and one or more inner uprights.
    Type: Grant
    Filed: July 14, 1997
    Date of Patent: October 19, 1999
    Assignee: Optonol Ltd.
    Inventors: Jacob Richter, Gregory Pinchasik, Ira Yaron
  • Patent number: 5868697
    Abstract: An ophthalmic implant for treatment of glaucoma, a delivery device for implanting such an implant, and a method of implanting such an implant. The implant includes a tube having an inlet end, an outlet end, and a tube passage therebetween, and a disk connected to the tube at the outlet end of the tube. The tube passage has a cross-sectional area sufficiently small to inhibit the flow of aqueous humor through the tube passage. The implant provides a bleb of aqueous humor under the conjunctiva so that the bleb and the elasticity of the conjunctiva assist in regulating the flow of aqueous humor through the tube as a function of the intraocular pressure. The tube at its inlet end has a beveled surface facing away from the iris and one or more circumferential holes. One or more retention projections are provided for anchoring and may be extended outwardly when the implant is implanted in the eyeball. The disk has an outer rim and one or more inner uprights.
    Type: Grant
    Filed: March 27, 1996
    Date of Patent: February 9, 1999
    Assignee: Optonol Ltd.
    Inventors: Jacob Richter, Gregory Pinchasik, Ira Yaron
  • Patent number: 5702414
    Abstract: An ophthalmic implant for treatment of glaucoma, a delivery device for implanting such an implant, and a method of implanting such an implant. The implant includes a tube having an inlet end, an outlet end, and a tube passage therebetween, and a disk connected to the tube at the outlet end of the tube. The tube passage has a cross-sectional area sufficiently small to inhibit the flow of aqueous humor through the tube passage. The implant provides a bleb of aqueous humor under the conjunctiva so that the bleb and the elasticity of the conjunctiva assist in regulating the flow of aqueous humor through the tube as a function of the IOP. The tube at its inlet end has a beveled surface facing away from the iris and one or more circumferential holes. One or more retention projections are provided for anchoring and may be extended outwardly when the implant is implanted in the eyeball. The disk has an outer rim and one or more inner uprights.
    Type: Grant
    Filed: September 5, 1996
    Date of Patent: December 30, 1997
    Assignee: Optonol Ltd
    Inventors: Jacob Richter, Gregory Pinchasik, Ira Yaron