Patents Assigned to Orion Genomics LLC
  • Sample collection device
    Patent number: 11268885
    Abstract: A sampling device having a lower portion with a sample container. A cap is moveably attached with the lower portion and includes a cutting edge configured for cutting a leaf. When the cap is attached to the lower portion with a leaf there between, a leaf sample is deposited into the sample container of the lower portion. The cap includes a vent in fluid communication with the sample container such that the leaf sample is dried. A detachable label can extend from the lower portion.
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: March 8, 2022
    Assignee: Orion Genomics LLC
    Inventors: Jacob Paul Hendrickx, Michael Sylvester Botzet, Nathan D. Lakey, Anthony D. Favello
  • Sample collection device
    Patent number: 10508975
    Abstract: A sampling device having a lower portion with a sample container. A cap is moveably attached with the lower portion and includes a cutting edge configured for cutting a leaf. When the cap is attached to the lower portion with a leaf there between, a leaf sample is deposited into the sample container of the lower portion. The cap includes a vent in fluid communication with the sample container such that the leaf sample is dried. A detachable label can extend from the lower portion.
    Type: Grant
    Filed: June 6, 2016
    Date of Patent: December 17, 2019
    Assignee: Orion Genomics LLC
    Inventors: Jacob Paul Hendrickx, Michael Sylvester Botzet, Nathan D. Lakey, Anthony D. Favello
  • NOVEL SINGLE NUCLEOTIDE POLYMORPHISMS AND COMBINATIONS OF NOVEL AND KNOWN POLYMORPHISMS FOR DETERMINING THE ALLELE-SPECIFIC EXPRESSION OF THE IGF2 GENE
    Publication number: 20140162255
    Abstract: Single nucleotide polymorphisms and uses for determining the imprinting status of the Insulin Growth Factor-2 gene in a clinical specimen are described.
    Type: Application
    Filed: August 7, 2013
    Publication date: June 12, 2014
    Applicant: Orion Genomics LLC
    Inventors: Jared Ordway, Nathan Lakey, Rebecca Maloney, Theresa Rohlfing
  • NOVEL SINGLE NUCLEOTIDE POLYMORPHISMS AND COMBINATIONS OF NOVEL AND KNOWN POLYMORPHISMS FOR DETERMINING THE ALLELE-SPECIFIC EXPRESSION OF THE IGF2 GENE
    Publication number: 20130317125
    Abstract: Single nucleotide polymorphisms and uses for determining the imprinting status of the Insulin Growth Factor-2 gene in a clinical specimen are described.
    Type: Application
    Filed: August 7, 2013
    Publication date: November 28, 2013
    Applicant: Orion Genomics LLC
    Inventors: Jared Ordway, Nathan Lakey, Rebecca Maloney, Theresa Rohlfing
  • NOVEL SINGLE NUCLEOTIDE POLYMORPHISMS AND COMBINATIONS OF NOVEL AND KNOWN POLYMORPHISMS FOR DETERMINING THE ALLELE-SPECIFIC EXPRESSION OF THE IGF2 GENE
    Publication number: 20130317124
    Abstract: Single nucleotide polymorphisms and uses for determining the imprinting status of the Insulin Growth Factor-2 gene in a clinical specimen are described.
    Type: Application
    Filed: August 7, 2013
    Publication date: November 28, 2013
    Applicant: Orion Genomics LLC
    Inventors: Jared Ordway, Nathan Lakey, Rebecca Maloney, Theresa Rohlfing
  • DETECTION OF NUCLEIC ACID SEQUENCES ADJACENT TO REPEATED SEQUENCES
    Publication number: 20130316339
    Abstract: The present invention provides methods of quantifying a target locus adjacent to an extended repeat sequence in genomic DNA. The present invention further provides methods and kits for detecting methylation at a target locus adjacent to an extended repeat sequence in genomic DNA.
    Type: Application
    Filed: August 31, 2011
    Publication date: November 28, 2013
    Applicant: ORION GENOMICS LLC
    Inventors: Jared Ordway, Blaire Bacher
  • NOVEL SINGLE NUCLEOTIDE POLYMORPHISMS AND COMBINATIONS OF NOVEL AND KNOWN POLYMORPHISMS FOR DETERMINING THE ALLELE-SPECIFIC EXPRESSION OF THE IGF2 GENE
    Publication number: 20130177911
    Abstract: Single nucleotide polymorphisms and uses for determining the imprinting status of the Insulin Growth Factor-2 gene in a clinical specimen are described.
    Type: Application
    Filed: March 8, 2013
    Publication date: July 11, 2013
    Applicant: Orion Genomics LLC
    Inventors: Jared ORDWAY, Nathan Lakey, Rebecca Maloney, Theresa Rahlfing
  • Single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the IGF2 gene
    Patent number: 8420315
    Abstract: Single nucleotide polymorphisms and uses for determining the imprinting status of the Insulin Growth Factor-2 gene in a clinical specimen are described.
    Type: Grant
    Filed: August 6, 2008
    Date of Patent: April 16, 2013
    Assignee: Orion Genomics LLC
    Inventors: Jared Ordway, Nathan Lakey, Rebecca Maloney, Theresa Rohlfing
  • Methods for quantitative determination of methylation density in a DNA locus
    Patent number: 8361719
    Abstract: The present invention is a novel method of determining the average DNA methylation density of a locus of interest within a population of DNA fragments.
    Type: Grant
    Filed: October 1, 2010
    Date of Patent: January 29, 2013
    Assignee: Orion Genomics LLC
    Inventors: Jeffrey A. Jeddeloh, Nathan D. Lakey
  • GENE METHYLATION IN CANCER DIAGNOSIS
    Publication number: 20120122090
    Abstract: The present invention provides DNA biomarker sequences that are differentially methylated in samples from normal individuals and individuals with cancer. The invention further provides methods of identifying differentially methylated DNA biomarker sequences and their use the detection and diagnosis of cancer.
    Type: Application
    Filed: May 5, 2011
    Publication date: May 17, 2012
    Applicant: ORION GENOMICS LLC
    Inventors: MUHAMMAD A. BUDIMAN, JEFFREY A. JEDDELOH, REBECCA MALONEY, YULIA KORSHUNOVA
  • GENE METHYLATION IN CANCER DIAGNOSIS
    Publication number: 20120100541
    Abstract: The present invention provides DNA biomarker sequences that are differentially methylated in samples from normal individuals and individuals with cancer. The invention further provides methods of identifying differentially methylated DNA biomarker sequences and their use in detecting and diagnosing cancer.
    Type: Application
    Filed: October 24, 2011
    Publication date: April 26, 2012
    Applicant: Orion Genomics LLC
    Inventors: Jared Ordway, Jeffrey A. Jeddeloh, Joseph Bedell
  • METHODS FOR QUANTITATIVE DETERMINATION OF METHYLATION DENSITY IN A DNA LOCUS
    Publication number: 20120100535
    Abstract: The present invention is a novel method of determining the average DNA methylation density of a locus of interest within a population of DNA fragments.
    Type: Application
    Filed: October 1, 2010
    Publication date: April 26, 2012
    Applicant: Orion Genomics LLC
    Inventors: Jeffrey A. Jeddeloh, Nathan D. Lakey
  • Differential enzymatic fragmentation
    Patent number: 8163485
    Abstract: The present invention provides methods for detecting the presence of methylation at a locus within a population of nucleic acids.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: April 24, 2012
    Assignee: Orion Genomics, LLC
    Inventors: Jeffrey A. Jeddeloh, Nathan D. Lakey
  • Differential enzymatic fragmentation by whole genome amplification
    Patent number: 8088581
    Abstract: The present invention provides methods for detecting the presence of methylation at a locus within a population of nucleic acids.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: January 3, 2012
    Assignee: Orion Genomics LLC
    Inventors: Nathan D. Lakey, Jeffrey A. Jeddeloh, Yulia Korshunova
  • Novel Single Nucleotide Polymorphisms and Combinations of Novel and Known Polymorphisms for Determining the Allele-Specific Expression of the IGF2 Gene
    Publication number: 20110311967
    Abstract: Single nucleotide polymorphisms and uses for determining the imprinting status of the Insulin Growth Factor-2 gene in a clinical specimen are described.
    Type: Application
    Filed: August 6, 2008
    Publication date: December 22, 2011
    Applicant: Orion Genomics LLC
    Inventors: Jared Ordway, Nathan Lakey, Rebecca Maloney, Theresa Rohlfing
  • Gene methylation in cancer diagnosis
    Patent number: 8067168
    Abstract: The present invention provides DNA biomarker sequences that are differentially methylated in samples from normal individuals and individuals with cancer. The invention further provides methods of identifying differentially methylated DNA biomarker sequences and their use in detecting and diagnosing cancer.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: November 29, 2011
    Assignee: Orion Genomics LLC
    Inventors: Jared Ordway, Jeffrey A. Jeddeloh, Joseph Bedell
  • Gene methylation in cancer diagnosis
    Patent number: 7960112
    Abstract: The present invention provides DNA biomarker sequences that are differentially methylated in samples from normal individuals and individuals with cancer. The invention further provides methods of identifying differentially methylated DNA biomarker sequences and their use the detection and diagnosis of cancer.
    Type: Grant
    Filed: February 1, 2008
    Date of Patent: June 14, 2011
    Assignee: Orion Genomics LLC
    Inventors: Muhammad A. Budiman, Jeffrey A. Jeddeloh, Rebecca Maloney, Yulia Korshunova
  • Differential enzymatic fragmentation by whole genome amplification
    Publication number: 20110076726
    Abstract: The present invention provides methods for detecting the presence of methylation at a locus within a population of nucleic acids.
    Type: Application
    Filed: October 10, 2008
    Publication date: March 31, 2011
    Applicant: Orion Genomics LLC
    Inventors: Nathan D. Lakey, Jeffrey A. Jeddeloh, Yulia Korshunova
  • Methods for quantitative determination of methylation density in a DNA locus
    Patent number: 7910296
    Abstract: The present invention is a novel method of determining the average DNA methylation density of a locus of interest within a population of DNA fragments.
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: March 22, 2011
    Assignee: Orion Genomics LLC
    Inventors: Jeffrey A. Jeddeloh, Nathan D. Lakey
  • Differential enzymatic fragmentation
    Patent number: 7901880
    Abstract: The present invention provides methods for detecting the presence of methylation at a locus within a population of nucleic acids.
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: March 8, 2011
    Assignee: Orion Genomics LLC
    Inventors: Jeffrey A. Jeddeloh, Nathan D. Lakey