Patents Assigned to OSAKA ORGANIC CHEMICAL INDUSTRIES LTD.
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Patent number: 11530286Abstract: The present invention provides a protein aggregation inhibitor for use in preventing aggregation of a protein, containing a crosslinked polymer obtained by polymerizing polymerizable polymer components containing a sulfobetaine polymer obtained by polymerizing monomer components containing a sulfobetaine monomer, the sulfobetaine monomer, and a crosslinkable monomer.Type: GrantFiled: May 30, 2017Date of Patent: December 20, 2022Assignees: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Kazuaki Matsumura, Rajan Robin, Yoko Taniyama, Yoshiyuki Saruwatari
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Patent number: 10995160Abstract: The present invention provides a protein aggregation inhibitor for use in preventing aggregation of a protein, which contains a terminal sulfanyl group-containing sulfobetaine polymer having a repeat unit derived from a sulfobetaine monomer represented by the formula (II), and a noble metal particle, and in which the terminal sulfanyl group-containing sulfobetaine polymer is chemisorbed on the noble metal particle by the sulfanyl group (the groups in the following formula are as defined in the DESCRIPTION).Type: GrantFiled: June 29, 2017Date of Patent: May 4, 2021Assignees: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Kazuaki Matsumura, Rajan Robin, Yoko Taniyama, Yoshiyuki Saruwatari
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Patent number: 10913806Abstract: A (meth)acrylic conductive material which contains a (meth)acrylic elastomer and a conductive agent, and which is characterized in that: the (meth)acrylic elastomer is obtained by polymerizing a monomer component containing a (meth)acrylic monomer represented by formula (I) (wherein R1 represents a hydrogen atom or a methyl group; and R2 represents an alkyl group having 1-10 carbon atoms, which may have a hydroxyl group or a halogen atom, or an alkoxyalkyl group having 2-12 carbon atoms, which may have a hydroxyl group); and the (meth)acrylic elastomer has a weight average molecular weight of 1,200,000 to 10,000,000 and a molecular weight distribution (weight average molecular weight/number average molecular weight) of 1-6.Type: GrantFiled: July 19, 2017Date of Patent: February 9, 2021Assignee: OSAKA ORGANIC CHEMICAL INDUSTRY LTD.Inventors: Kanami Fujii, Yuya Tomimori, Mitsuhiro Kouda
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Patent number: 10822298Abstract: A (meth)acrylic monomer is represented by general formula (1) (wherein R1 represents a hydrogen atom or a methyl group; R2 to R4 independently represent —CH3 or —CH2—O—R5, wherein at least one of R2 to R4 represents —CH2—O—R5; R5 represents an alkyl group having 1 to 4 carbon atoms; and Z represents multiple atoms necessary for the formation of an alicyclic hydrocarbon group having 3 to 10 carbon atoms in conjunction with a carbon atom). The (meth)acrylic monomer has a property of high acid degradability and can be removed by the action of an acid.Type: GrantFiled: October 4, 2017Date of Patent: November 3, 2020Assignee: OSAKA ORGANIC CHEMICAL INDUSTRY LTD.Inventors: Naoko Tanikawa, Toru Sugiue, Naoki Shima
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Publication number: 20200332044Abstract: The present invention provides a protein aggregation inhibitor for use in preventing aggregation of a protein, containing a crosslinked polymer obtained by polymerizing polymerizable polymer components containing a sulfobetaine polymer obtained by polymerizing monomer components containing a sulfobetaine monomer, the sulfobetaine monomer, and a crosslinkable monomer.Type: ApplicationFiled: May 30, 2017Publication date: October 22, 2020Applicants: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Kazuaki MATSUMURA, Rajan ROBIN, Yoko TANIYAMA, Yoshiyuki SARUWATARI
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Patent number: 10774025Abstract: The present invention provides a production method of a multifunctional acrylate with a reduced tin content which includes adding an acid to a mixture containing an organotin compound and a multifunctional acrylate and distilling the mixture containing the acid.Type: GrantFiled: April 26, 2018Date of Patent: September 15, 2020Assignee: OSAKA ORGANIC CHEMICAL INDUSTRY LTD.Inventors: Keisuke Ito, Shigeaki Matsumoto, Keita Shigematsu
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Patent number: 10624831Abstract: A cosmetic is characterized by containing a polymer which is produced by polymerizing a fluorine atom-containing monomer represented by formula (I) (wherein R1 represents a hydrogen atom or a methyl group; R2 represents a hydrogen atom or a fluorine atom; m is an integer of 0 or 1 to 4; and n is an integer of 1 to 12), (B) a betaine monomer represented by formula (II) (wherein R3 represents a hydrogen atom or a methyl group; R4 and R5 independently represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; p represents an integer of 1 to 4: and q represents an integer of 1 to 4) and (C) a monomer component containing an alkyl (meth)acrylate represented by formula (III) (wherein R6 represents a hydrogen atom or a methyl group and R7 represents an alkyl group having 8 to 22 carbon atoms) with one another.Type: GrantFiled: February 2, 2016Date of Patent: April 21, 2020Assignees: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., SHISEIDO COMPANY, LTD.Inventors: Hideyuki Aoshima, Daisuke Iitsuka, Takumi Watanabe, Kazuyuki Miyazawa
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Publication number: 20200048178Abstract: The present invention provides a production method of a multifunctional acrylate with a reduced tin content which includes adding an acid to a mixture containing an organotin compound and a multifunctional acrylate and distilling the mixture containing the acid.Type: ApplicationFiled: April 26, 2018Publication date: February 13, 2020Applicant: OSAKA ORGANIC CHEMICAL INDUSTRY LTD.Inventors: Keisuke ITO, Shigeaki MATSUMOTO, Keita SHIGEMATSU
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Publication number: 20190161563Abstract: The present invention provides a protein aggregation inhibitor for use in preventing aggregation of a protein, which contains a terminal sulfanyl group-containing sulfobetaine polymer having a repeat unit derived from a sulfobetaine monomer represented by the formula (II), and a noble metal particle, and in which the terminal sulfanyl group-containing sulfobetaine polymer is chemisorbed on the noble metal particle by the sulfanyl group (the groups in the following formula are as defined in the DESCRIPTION).Type: ApplicationFiled: June 29, 2017Publication date: May 30, 2019Applicants: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Kazuaki MATSUMURA, Rajan ROBIN, Yoko TANIYAMA, Yoshiyuki SARUWATARI
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Publication number: 20180305573Abstract: Provided are a clear coating composition which is used for top coats, the composition containing a crosslinking agent and a functional group-containing (meth)acrylate polymer formed by polymerization of a monomer component that includes an aromatic ring-containing (meth)acrylate and a functional group-containing monomer. Also provided is a clear coat composition which is used for top coats, the composition containing a crosslinking agent and a functional group-containing (meth)acrylate polymer formed by polymerization of a monomer component that includes a functional group-containing monomer and a fluorine atom-containing monomer. This clear coat composition has low colorability, has a high refractive index without the use of a filler, provides excellent glossy even when a filler is used, and can be applied to a thick film.Type: ApplicationFiled: June 29, 2018Publication date: October 25, 2018Applicants: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., HONDA MOTOR CO., LTD.Inventors: Mitsuko Kitanohara, Kazuyoshi Matsuoka, Yoshiyuki Saruwatari, Keisuke Kojima, Masuo Kondo
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Patent number: 10040965Abstract: Provided are a clear coating composition which is used for top coats, the composition containing a crosslinking agent and a functional group-containing (meth)acrylate polymer formed by polymerization of a monomer component that includes an aromatic ring-containing (meth)acrylate and a functional group-containing monomer. Also provided is a clear coat composition which is used for top coats, the composition containing a crosslinking agent and a functional group-containing (meth)acrylate polymer formed by polymerization of a monomer component that includes a functional group-containing monomer and a fluorine atom-containing monomer. This clear coat composition has low colorability, has a high refractive index without the use of a filler, provides excellent glossy even when a filler is used, and can be applied to a thick film.Type: GrantFiled: November 19, 2014Date of Patent: August 7, 2018Assignees: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., HONDA MOTOR CO., LTD.Inventors: Mitsuko Kitanohara, Kazuyoshi Matsuoka, Yoshiyuki Saruwatari, Keisuke Kojima, Masuo Kondo
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Patent number: 9976000Abstract: An aqueous gel that is prepared by gelling a polymer components, the polymer components containing polymer A, which is obtained by polymerizing a monomer component containing a betaine monomer represented by the formula (I): wherein R1 represents hydrogen atom or an alkyl group, R2 represents an alkylene, arylene, aralkylene, —COOH— or —CONH— group; R3 and R4 represent an alkyl group, and R5 represents an alkylene group, and a polymer B, which is obtained by polymerizing a monomer component containing an acidic monomer represented by the formula (II): wherein R1 represents hydrogen atom or an alkyl group; R6 represents an optionally neutralized sulfonate group, an optionally neutralized phosphate group, or an alkyl, aryl, aralkyl, carboxyl or amino group carrying an optionally neutralized sulfonate group or an optionally neutralized phosphate group.Type: GrantFiled: November 7, 2014Date of Patent: May 22, 2018Assignees: NATIONAL UNIVERSITY CORP. HOKKAIDO UNIVERSITY, OSAKA ORGANIC CHEMICAL INDUSTRIES LTD.Inventors: Jian Ping Gong, Takayuki Kurokawa, Haiyan Yin, Taigo Akasaki, Yoshiyuki Saruwatari
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Publication number: 20180118859Abstract: Provided is a protein aggregation inhibitor capable of inhibiting aggregation of a protein even when the protein is heated, and further, capable of inhibiting a decrease in the protein activity even when the protein is heated, which characteristically contains a sulfobetaine polymer obtained by polymerizing monomer components containing sulfobetaine monomer represented by the formula (I): wherein R1 is a hydrogen atom or a methyl group, R2 is an alkylene group having a carbon number of 1-4, R3 is an alkyl group having a carbon number of 1-4, R4 is an alkylene group having a carbon number of 1-4, and X is an —NH— group or an —O— group.Type: ApplicationFiled: May 10, 2016Publication date: May 3, 2018Applicants: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Kazuaki MATSUMURA, Rajan ROBIN, Tsuyoshi FURUKAWA, Kentaro MAEHARA, Yoshiyuki SARUWATARI
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Publication number: 20180028430Abstract: A cosmetic is characterized by containing a polymer which is produced by polymerizing a fluorine atom-containing monomer represented by formula (I) (wherein R1 represents a hydrogen atom or a methyl group; R2 represents a hydrogen atom or a fluorine atom; m is an integer of 0 or 1 to 4; and n is an integer of 1 to 12), (B) a betaine monomer represented by formula (II) (wherein R3 represents a hydrogen atom or a methyl group; R4 and R5 independently represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; p represents an integer of 1 to 4: and q represents an integer of 1 to 4) and (C) a monomer component containing an alkyl (meth)acrylate represented by formula (III) (wherein R6 represents a hydrogen atom or a methyl group and R7 represents an alkyl group having 8 to 22 carbon atoms) with one another.Type: ApplicationFiled: February 2, 2016Publication date: February 1, 2018Applicants: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., SHISEIDO COMPANY, LTD.Inventors: Hideyuki AOSHIMA, Daisuke IITSUKA, Takumi WATANABE, Kazuyuki MIYAZAWA
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Patent number: 9795549Abstract: Provided is a composition containing, as an alkane polyol, a C4-18 1,2-alkane polyol in which the degradation over time of the C4-18 1,2-alkane polyol, which has inferior chemical stability and degrades easily, is suppressed, the composition being suitable for use in a cosmetic, an inkjet ink, a fiber or a coating material such as a paint. A composition containing 1,2-alkane polyol that can be used in a cosmetic, an inkjet ink, a raw material for fibers or a coating material, the alkane polyol being a C4-18 1,2-alkane polyol, and the composition containing a radical scavenger.Type: GrantFiled: October 9, 2015Date of Patent: October 24, 2017Assignee: OSAKA ORGANIC CHEMICAL INDUSTRY LTD.Inventors: Yutaka Hoshino, Takahiro Mukaiyama
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Patent number: 9670129Abstract: A process for preparing 4-hydroxybutyl acrylate by transesterifying an alkyl acrylate with 1,4-butanediol in the presence of a dialkyltin oxide such that each of the alkyl groups has 4 to 8 carbon atoms, characterized in that the amount of the dialkyltin oxide is adjusted to 0.00001 to 0.01 moles per one mole of the alkyl acrylate.Type: GrantFiled: October 17, 2014Date of Patent: June 6, 2017Assignee: OSAKA ORGANIC CHEMICAL INDUSTRY LTD.Inventors: Yukio Tanaka, Kohei Okamura, Keisuke Ito
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Patent number: 9513545Abstract: A compound represented by the following formula (I), wherein R1 is a hydrogen atom, a halogen atom, a methyl group or a trifluoromethyl group.Type: GrantFiled: July 26, 2011Date of Patent: December 6, 2016Assignee: Osaka Organic Chemical Industry Ltd.Inventors: Shinji Tanaka, Yoshitaka Uenoyama, Hidetoshi Ono, Naoya Kawano, Katsuki Ito
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Publication number: 20160297984Abstract: Provided are a clear coating composition which is used for top coats, the composition containing a crosslinking agent and a functional group-containing (meth)acrylate polymer formed by polymerization of a monomer component that includes an aromatic ring-containing (meth)acrylate and a functional group-containing monomer. Also provided is a clear coat composition which is used for top coats, the composition containing a crosslinking agent and a functional group-containing (meth)acrylate polymer formed by polymerization of a monomer component that includes a functional group-containing monomer and a fluorine atom-containing monomer. This clear coat composition has low colorability, has a high refractive index without the use of a filler, provides excellent glossy even when a filler is used, and can be applied to a thick film.Type: ApplicationFiled: November 19, 2014Publication date: October 13, 2016Applicants: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., HONDA MOTOR CO., LTD.Inventors: Mitsuko Kitanohara, Kazuyoshi Matsuoka, Yoshiyuki Saruwatari, Keisuke Kojima, Masuo Kondo
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Patent number: 9434858Abstract: A hydrophilic coating agent for use in the formation of a coating film that can keep hydrophilicity, an anti-fogging property and an anti-fogging effect thereof and has water resistance, the coating agent including an alkoxysilyl-group-containing compound, a film which has an anti-fogging property and can be produced by shaping the hydrophilic coating agent into a film-like form; and a product which has an anti-fogging layer formed on the surface thereof, wherein the anti-fogging layer is formed from the hydrophilic coating agent.Type: GrantFiled: May 28, 2015Date of Patent: September 6, 2016Assignee: OSAKA ORGANIC CHEMICAL INDUSTRY LTD.Inventors: Kazuyoshi Matsuoka, Yoshiyuki Saruwatari, Masayuki Ando
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Patent number: 9434927Abstract: A method for manufacturing a cell culture substrate obtained by forming a coating layer of a polymer on the surface of a substrate, wherein the polymer is formed by polymerizing a monomer component containing a nitrogen atom-containing monomer represented by formula (I): wherein R1 is hydrogen atom or methyl group, R2 is an alkylene group having 1 to 6 carbon atoms, each of R3 and R4 is independently an alkyl group having 1 to 4 carbon atoms, R5 is an alkylene group having 1 to 4 carbon atoms, and Y is oxygen atom or —NH— group, includes irradiating the polymer with ion beam at a predetermined position of the coating layer of the polymer, to remove the coating layer of the polymer irradiated with the ion beam.Type: GrantFiled: August 30, 2011Date of Patent: September 6, 2016Assignee: OSAKA ORGANIC CHEMICAL INDUSTRY LTD.Inventors: Hiromi Kitano, Yoshiyuki Saruwatari, Kazuyoshi Matsuoka