Patents Assigned to OXITEC LTD
  • SELF-LIMITING, SEX-SPECIFIC GENE AND METHODS OF USING
    Publication number: 20240093230
    Abstract: The invention provides a splice control module for sex-specific splicing and expression of a gene of interest. In certain embodiments, a dsx-based splice control module is used to express a lethal gene in an insect that is spliced in a sex-specific manner to impart lethality to female insects but not male insects.
    Type: Application
    Filed: October 18, 2023
    Publication date: March 21, 2024
    Applicant: Oxitec Ltd.
    Inventors: Luke ALPHEY, Tarig DAFA'ALLA, Amandine COLLADO, Simon WARNER, Kelly MATZEN, Sian SPINNER
  • Self-limiting, sex-specific gene and methods of using
    Patent number: 11827876
    Abstract: The invention provides a splice control module for sex-specific splicing and expression of a gene of interest. In certain embodiments, a dsx-based splice control module is used to express a lethal gene in an insect that is spliced in a sex-specific manner to impart lethality to female insects but not male insects.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: November 28, 2023
    Assignee: OXITEC LTD.
    Inventors: Luke Alphey, Tarig Dafa'alla, Amandine Collado, Simon Warner, Kelly Matzen, Sian Spinner
  • A SELF-LIMITING, SEX-SPECIFIC GENE AND METHODS OF USING
    Publication number: 20200407748
    Abstract: The invention provides a splice control module for sex-specific splicing and expression of a gene of interest. In certain embodiments, a dsx-based splice control module is used to express a lethal gene in an insect that is spliced in a sex-specific manner to impart lethality to female insects but not male insects.
    Type: Application
    Filed: August 9, 2017
    Publication date: December 31, 2020
    Applicant: OXITEC LTD.
    Inventors: Luke ALPHEY, Tarig DAFA'ALLA, Amandine COLLADO, Simon WARNER, Kelly MATZEN, Sian SPINNER
  • Multiplex amplification and detection
    Patent number: 10400276
    Abstract: The invention relates to the field of multiplex amplification. In particular, the invention relates to methods for assaying a sample for one or more nucleic acid targets in a single reaction based on the distinct melting temperatures or melting profiles of primers and/or probes. The invention also provides probes and kits for use in such methods.
    Type: Grant
    Filed: March 14, 2016
    Date of Patent: September 3, 2019
    Assignee: OXITEC LTD
    Inventor: Guoliang Fu
  • Multiplex amplification and detection
    Patent number: 9284607
    Abstract: The invention relates to the field of multiplex amplification. In particular, the invention relates to methods for assaying a sample for one or more nucleic acid targets in a single reaction based on the distinct melting temperatures or melting profiles of primers and/or probes. The invention also provides probes and kits for use in such methods.
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: March 15, 2016
    Assignee: OXITEC LTD
    Inventor: Guoliang Fu
  • STRAND DISPLACEMENT ACTIVITY OF MODIFIED POLYMERASES AND USES THEREOF
    Publication number: 20120115145
    Abstract: The present invention is directed to the use of the strand displacement activity of a modified polymerase. The present invention is more specifically directed to a modified Taq DNA polymerase, which exhibits strand displacement activity, whereas the native polymerase does not possess the strand displacement activity.
    Type: Application
    Filed: November 4, 2011
    Publication date: May 10, 2012
    Applicant: OXITEC LTD
    Inventor: Guoliang Fu