Patents Assigned to Oxyrane UK Limited
  • METHODS AND COMPOSITIONS FOR DISPLAYING A POLYPEPTIDE ON A YEAST CELL SURFACE
    Publication number: 20130096281
    Abstract: Provided herein are methods and compositions for use in displaying a polypeptide (e.g., an antibody polypeptide or an antibody polypeptide fragment) on the surface of a yeast cell. Exemplary yeast that can be used in conjunction with various methods and compositions disclosed herein include those of the genus Yarrowia, e.g., Yarrowia lipolytica.
    Type: Application
    Filed: January 21, 2011
    Publication date: April 18, 2013
    Applicant: OXYRANE UK LIMITED
    Inventors: Stefan Ryckaert, Guillaume Lerondel
  • YEAST STRAINS PRODUCING MAMMALIAN-LIKE COMPLEX N-GLYCANS
    Publication number: 20130053550
    Abstract: Described herein are methods and genetically engineered fungal cells useful for producing target molecules containing mammalian-like complex N-glycans or containing intermediates in a mammalian glycosylation pathway.
    Type: Application
    Filed: November 19, 2010
    Publication date: February 28, 2013
    Applicant: OXYRANE UK LIMITED
    Inventors: Steven Christian Jozef Geysens, Wouter Vervecken
  • and HAC1 nucleic acids
    Patent number: 8026083
    Abstract: Described herein are methods and genetically engineered cells useful for producing an altered N-glycosylation form of a target molecule. Also described are methods and molecules with altered N-glycosylation useful for treating a variety of disorders such as metabolic disorders.
    Type: Grant
    Filed: April 3, 2008
    Date of Patent: September 27, 2011
    Assignees: Oxyrane UK Limited, VIB vzw, Universiteit Gent
    Inventors: Nico Luc Marc Callewaert, Wouter Vervecken, Karen Jacqueline Marcel De Pourcq, Steven Christian Jozef Geysens, Mouna Guerfal
  • Methods of Obtaining Optically Active Epoxides and Vicinal Diols from Styrene Oxides
    Publication number: 20090275077
    Abstract: The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific meso-epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors. Also embraced by the invention are methods for obtaining containing such nucleic acid molecules, and cells containing such vectors.
    Type: Application
    Filed: February 17, 2009
    Publication date: November 5, 2009
    Applicant: Oxyrane (UK) Limited
    Inventors: Adriana Leonora Botes, Jeanette Lotter, Michel Labuschagne, Robin Kumar Mitra
  • Process for Synthesizing Atazanavir
    Publication number: 20090270499
    Abstract: This invention relates to a process for synthesizing Atazanvir, including novel intermediates and novel steps to various intermediates along the synthetic pathway.
    Type: Application
    Filed: April 24, 2008
    Publication date: October 29, 2009
    Applicant: OXYRANE (UK) LIMITED
    Inventor: Weiping Chen