Patents Assigned to PARI Pharma GmbH
  • Patent number: 11707758
    Abstract: An aerosol generator for generating an aerosol from a fluid, comprising: a vibratable membrane having a first side for being in contact with the fluid and an opposite second side, the membrane having a plurality of through holes penetrating the membrane in an extension direction from the first side to the second side, whereby the fluid passes the through holes from the first side to the second side when the membrane is vibrated for generating the aerosol at the second side, each through hole having along its extension direction a smallest diameter, a larger diameter that is larger than the smallest diameter and defined by that diameter that is closest to triple, preferably twice said smallest diameter, each through hole having a nozzle portion defined by that continuous portion of the through hole in the extension direction comprising the smallest diameter of the through hole and bordered by the larger diameter of the through hole, wherein the ratio of the total length of each through hole in the extension di
    Type: Grant
    Filed: October 19, 2021
    Date of Patent: July 25, 2023
    Assignee: PARI Pharma GmbH
    Inventors: Harald Schulz, Philipp Holzmann, Dominique Mutschmann, Michael Hahn
  • Publication number: 20230119086
    Abstract: The invention relates to an aerosol delivery device comprising an aerosol generator for generating an aerosol in the aerosol delivery device, a sensor configured to detect a use of the aerosol delivery device for aerosol treatment, and a controller configured to deactivate the aerosol generator if no use of the aerosol delivery device for aerosol treatment is detected by the sensor. Further, the invention relates to a method for operating an aerosol delivery device, comprising the steps of operating an aerosol generator for generating an aerosol in the aerosol delivery device, detecting a use of the aerosol delivery device for aerosol treatment by means of a sensor, and deactivating the aerosol generator by means of a controller if no use of the aerosol delivery device for aerosol treatment is detected by the sensor.
    Type: Application
    Filed: December 15, 2022
    Publication date: April 20, 2023
    Applicant: PARI Pharma GmbH
    Inventor: Martin Knoch
  • Patent number: 11610473
    Abstract: The present invention relates to a control device for controlling an operation of an aerosol nebulizer system (30), said aerosol nebulizer system (30) comprising an aerosol generator (31) for nebulizing a liquid and a plurality of sensor units (38a, 38b, 38c, 38d, 38e), said control device (20) comprising: a communication unit (21), configured to establish a wireless communication connection and to perform data transmission with the aerosol nebulizer system (30), a sensor data control unit (22), configured to trigger a selection of sensor data related to the sensor units (38a, 38b, 38c, 38d, 38e) to be wirelessly transmitted to the control device (20).
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: March 21, 2023
    Assignee: PARI Pharma GmbH
    Inventors: Matthias Finke, Carola Fuchs, Björn Eschrich, Edgard Osswald, Philipp Kroneberg, Michael Hahn, Ingo Schraut, Sascha Roeder
  • Publication number: 20230028709
    Abstract: Provided is a control device (20, 20a) for controlling an operation of an aerosol nebulizer system (30), said aerosol nebulizer (system 30) comprising an aerosol generator (31) for nebulizing a liquid or an aerosol source for dispensing aerosol, said control device (20), 20a comprising: a communication unit (21, 21a), configured to establish a first wireless communication connection and to perform first data transmission with the aerosol nebulizer system (30), a control unit (22, 22a), configured to evaluate a progression of identifications received via the first data transmission and received in association with aerosol nebulizer data units respectively related to a usage of the aerosol nebulizer system (30).
    Type: Application
    Filed: December 22, 2020
    Publication date: January 26, 2023
    Applicant: PARI Pharma GmbH
    Inventors: Carola Fuchs, Matthias Finke, Philippine Reimpell, David Fiebig
  • Patent number: 11547822
    Abstract: The invention relates to an aerosol delivery device (10) comprising an aerosol generator (3) for generating an aerosol in the aerosol delivery device (10), a sensor (5) configured to detect a use of the aerosol delivery device (10) for aerosol treatment, and a controller (7) configured to deactivate the aerosol generator (3) if no use of the aerosol delivery device (10) for aerosol treatment is detected by the sensor (5). Further, the invention relates to a method for operating an aerosol delivery device (10), comprising the steps of operating an aerosol generator (3) for generating an aerosol in the aerosol delivery device (10), detecting a use of the aerosol delivery device (10) for aerosol treatment by means of a sensor (5), and deactivating the aerosol generator (3) by means of a controller (7) if no use of the aerosol delivery device (10) for aerosol treatment is detected by the sensor (5).
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: January 10, 2023
    Assignee: PARI Pharma GmbH
    Inventor: Martin Knoch
  • Patent number: 11471617
    Abstract: The invention relates to methods for generating an aerosol by nebulization of a composition comprising polyclonal immunoglobulin (Ig). The selection of an efficient membrane nebulizer and a composition optimized for nebulization with such membrane nebulizer results in a particularly efficient method of generating an aerosol for administration of Ig to the respiratory tract.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: October 18, 2022
    Assignees: CSL BEHRING AG, PARI PHARMA GMBH, MEDIZINISCHE HOCHSCHULE HANNOVER
    Inventors: Cédric Pierre Vonarburg, Karin Steinfuehrer, Ulrich Baumann
  • Patent number: 11419993
    Abstract: Inhalator comprising an aerosol generator configured to generate an aerosol by nebulizing a fluid and a controller configured to control operation of the aerosol generator and a housing accommodating at least the aerosol generator and the controller, the housing having a base for supporting the housing on a horizontal surface, wherein a portion of the housing accommodating at least a portion of the controller is arranged further away from the base than the aerosol generator as seen in a vertical direction, when the base is supported on the horizontal surface.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: August 23, 2022
    Assignee: PARI Pharma GmbH
    Inventors: Tom McPherson Allnutt, Wolfgang Achtzehner, Thomas Gallem, Uwe Hetzer
  • Publication number: 20220226856
    Abstract: The present invention relates to a membrane unit for generating an aerosol in an aerosol therapy device, the membrane unit comprising a membrane (1) having an area (6) comprising a plurality of through-holes for nebulizing a fluid and a flange (7) circumferentially surrounding the area (6), and a substrate (2) having an opening (8) wherein the flange (7) of the membrane (1) is welded to the substrate (2) so that the area (6) is located in the opening (8) wherein the weld (5) comprises at least three discontinuous welds (5c) arranged at a distance from each other a long a circumference of the opening (8) and a first annular weld (5b) circumferentially surrounding the opening (8).
    Type: Application
    Filed: April 27, 2020
    Publication date: July 21, 2022
    Applicant: PARI Pharma GmbH
    Inventors: Hans-Lukas Anzenberger, Martin Schlun, René Seifert
  • Publication number: 20220118198
    Abstract: The present disclosure relates to a mouthpiece (40) for delivering an aerosol supplied by a nebulizer (100) to a user, the mouthpiece (40) comprising a body (46) defining a fluid path (47) from an inlet port (41) connectable to the nebulizer (100) to an inhalation opening (42) to be received in the mouth of a user and a filter (30). The filter (30) has a filter base (31) in fluid communication with the fluid path (47), a filter top (33) detachably connected to the filter base (31) and a filter material (32) provided between the filter base (31) and the filter top (33). The filter top (33) has an exhalation opening (36) cooperating with a one-way valve (39) allowing exhaustion of fluid from the fluid path (47) through the filter material (32) to the outside of the mouthpiece upon exhalation of a patient through the inhalation opening (42). The body (46) and the filter base (31) are an integrated one-piece unit so as to provide for an easy to handle and comfortable mouthpiece (40).
    Type: Application
    Filed: December 3, 2019
    Publication date: April 21, 2022
    Applicant: PARI Pharma GmbH
    Inventors: Martin Knoch, Thomas Gallem, Mihaela Kaufmann
  • Publication number: 20220088630
    Abstract: An aerosol generator for generating an aerosol from a fluid, comprising: a vibratable membrane having a first side for being in contact with the fluid and an opposite second side, the membrane having a plurality of through holes penetrating the membrane in an extension direction from the first side to the second side, whereby the fluid passes the through holes from the first side to the second side when the membrane is vibrated for generating the aerosol at the second side, each through hole having along its extension direction a smallest diameter, a larger diameter that is larger than the smallest diameter and defined by that diameter that is closest to triple, preferably twice said smallest diameter, each through hole having a nozzle portion defined by that continuous portion of the through hole in the extension direction comprising the smallest diameter of the through hole and bordered by the larger diameter of the through hole, wherein the ratio of the total length of each through hole in the extension di
    Type: Application
    Filed: October 19, 2021
    Publication date: March 24, 2022
    Applicant: PARI Pharma GmbH
    Inventors: Harald Schulz, Philipp Holzmann, Dominique Mutschmann, Michael Hahn
  • Patent number: 11278683
    Abstract: An inhalation therapy device includes an atomizer for atomizing a drug which is advantageously present in the form of a fluid into an atomization chamber so that an aerosol or mist is provided in the atomization chamber. The patient or user can inhale the aerosol produced by the atomizer from the atomization chamber via a mouthpiece. The ampoule is inserted into an ampoule holder holding the fluid-containing ampoule. The inhalation therapy device also includes an opening unit for opening the fluid-containing ampoule. The ampoule holder advantageously includes a first part, disposed displaceably in relation to the opening unit, thereby allowing an ampoule present in the ampoule holder to be displaced in the direction of the opening unit.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: March 22, 2022
    Assignee: PARI Pharma GmbH
    Inventors: Uwe Hetzer, Thomas Gallem
  • Publication number: 20220062565
    Abstract: The invention relates to an aerosol delivery device (A, B) comprising an aerosol generator for generating an aerosol in the aerosol delivery device (A, B). The aerosol generator comprises a membrane (1) and a vibrator (7) which is configured to vibrate a fluid (3) and to aerosolise the fluid (3) by the membrane (1). The aerosol delivery device (A, B) further comprises a fluid reservoir (2) for receiving the fluid (3) to be aerosolised, wherein the fluid reservoir (2) is arranged in fluid communication with the membrane (1).
    Type: Application
    Filed: December 13, 2019
    Publication date: March 3, 2022
    Applicant: PARI Pharma GmbH
    Inventors: Markus Reinhart, Matthias Finke, Jan Pfrang, Martin Schlun
  • Publication number: 20220047818
    Abstract: The invention relates to an aerosol delivery device (A) comprising an aerosol generator for generating an aerosol in the aerosol delivery device (A). The aerosol generator comprises a membrane (1) and a vibrator (7) which is configured to vibrate a fluid (3) and to aerosolise the fluid (3) by the membrane (1). The aerosol delivery device (A) further comprises a fluid reservoir (2) for receiving the fluid (3) to be aerosolised, wherein the fluid reservoir (2) is arranged in fluid communication with the membrane (1).
    Type: Application
    Filed: December 13, 2019
    Publication date: February 17, 2022
    Applicant: PARI Pharma GmbH
    Inventors: Markus Reinhart, Matthias Finke, Wolfgang Achtzehner
  • Publication number: 20220016363
    Abstract: The present invention relates to a vibration head (210) for an aerosol generator (200), the vibration head (210) comprising: a membrane (8); a vibration generating element (4); and a secondary coil (220) configured for providing an inductive coupling with a primary coil (320) being connected with a controller (100) of the aerosol generator (200), the inductive coupling driving the vibration generating element (4) to vibrate the membrane (8) for generating the aerosol.
    Type: Application
    Filed: December 12, 2019
    Publication date: January 20, 2022
    Applicant: PARI Pharma GmbH
    Inventors: Wolfgang Achtzehner, Markus Reinhart, Matthias Finke
  • Patent number: 11154896
    Abstract: An aerosol generator for generating an aerosol from a fluid, comprising: a vibratable membrane having a first side for being in contact with the fluid and an opposite second side, the membrane having a plurality of through holes penetrating the membrane in an extension direction from the first side to the second side, whereby the fluid passes the through holes from the first side to the second side when the membrane is vibrated for generating the aerosol at the second side, each through hole having along its extension direction a smallest diameter, a larger diameter that is larger than the smallest diameter and defined by that diameter that is closest to triple, preferably twice said smallest diameter, each through hole having a nozzle portion defined by that continuous portion of the through hole in the extension direction comprising the smallest diameter of the through hole and bordered by the larger diameter of the through hole, wherein the ratio of the total length of each through hole in the extension di
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: October 26, 2021
    Assignee: PARI Pharma GmbH
    Inventors: Harald Schulz, Philipp Holzmann, Dominique Mutschmann, Michael Hahn
  • Patent number: 11077263
    Abstract: Disposable ampoule for use in an aerosol generating device, comprising: a medicament container that contains a medicament and is formed of a container body and a container bottom, and a predetermined break point that at least partly surrounds the container bottom, characterised by a collar that surrounds the predetermined break point at its outside and extends the container body over and beyond the container bottom.
    Type: Grant
    Filed: January 11, 2016
    Date of Patent: August 3, 2021
    Assignee: PARI Pharma GmbH
    Inventors: Mihaela Loenner, Thomas Gallem, Uwe Hetzer
  • Publication number: 20210113785
    Abstract: The present invention relates to a controller for an aerosol generator having a vibration head for generating an aerosol, the controller comprising: a connection unit (110) for connecting an electric contacting element (300), the electric contacting element being connectable with the vibration head (210); a detection unit (120) for detecting an electric energy storage capacity parameter related to the connected electric contacting element (300); and a determination unit (130) for determining whether the vibration head (210) is connected with the electric contacting element (300) based on the determined electric energy storage capacity parameter.
    Type: Application
    Filed: April 18, 2019
    Publication date: April 22, 2021
    Applicant: PARI Pharma GmbH
    Inventors: Thomas Gallem, Markus Reinhart
  • Patent number: 10758929
    Abstract: The invention relates to an aerosol generator (1), comprising a housing (20, 22), having a first holding member (24, 24?, 24?) and a second holding member (38), and a vibratable element (4) for generating an aerosol. The vibratable element (4) is at least partially accommodated in the housing (20, 22). The vibratable element (4) is contacted by and held between the first and second holding members (24, 24?, 24?; 38). The first holding member (24, 24?, 24?) is less flexible than the second holding member (38). Further, the invention relates to an aerosol delivery device comprising the aerosol generator (1).
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: September 1, 2020
    Assignee: PARI Pharma GmbH
    Inventors: Hans-Lukas Anzenberger, Carola Fuchs, Thomas Gallem, Uwe Hetzer, Philipp Holzmann, Gerhard Pumm
  • Patent number: 10744277
    Abstract: An aerosol delivery device includes an aerosol generator for generating an aerosol in the aerosol delivery device with a membrane and a vibrator which is configured to vibrate a fluid and to aerosolise the fluid by the membrane. The aerosol delivery device further includes a fluid reservoir for receiving the fluid to be aerosolised, the fluid reservoir being arranged in fluid communication with the membrane, a controller which is configured to sequentially operate the vibrator at a plurality of different vibration frequencies, a sensor which is configured to detect at least one electrical parameter of the vibrator for each of the plurality of different vibration frequencies, and a detector which is configured to detect the presence of fluid in contact with the membrane and/or in the fluid reservoir on the basis of the dependence of the detected values of the at least one electrical parameter on the vibration frequency.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: August 18, 2020
    Assignee: PARI Pharma GmbH
    Inventors: Matthias Finke, Dominique Mutschmann, Wolfgang Achtzehner, Philipp Holzmann
  • Patent number: D950044
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: April 26, 2022
    Assignee: PARI PHARMA GMBH
    Inventors: Kristina Hinz, Stefan Eckstein