Abstract: Atomizer for a ventilation machine with a ventilator, including a body with a first connection for connecting the atomizer to a ventilator and a second connection for connecting the atomizer to a line leading to a patient, wherein the body forms a flow channel from the first connection to the second connection; and an atomizing device for atomizing a fluid; wherein the atomizing device is disposed between the first connection and the second connection in the flow channel and adapted so that the fluid can be atomized substantially parallel to, and preferably in, the flow direction from the first connection to the second connection.

Abstract: The disclosure relates to an aerosol therapy device including: a housing; an aerosol generator, which is arranged in the housing; an air inlet, which is formed in the housing upstream of the aerosol generator; and an air outlet, which is formed in the housing downstream of the aerosol generator to administer the aerosol produced, wherein an air flow from the air inlet to the air outlet can be generated by a negative pressure at the air outlet, wherein the air flow flows around the aerosol generator, wherein a truncated-cone-shaped flow channel, the central axis of which extends in a curved manner, is arranged between the aerosol generator and the air outlet.

Abstract: Inhalator (50) comprising an aerosol generator (64) configured to generate an aerosol by nebulizing a fluid and a controller (24) configured to control operation of the aerosol generator and a housing (11, 51) accommodating at least the aerosol generator and the controller, the housing having a base (12) for supporting the housing on a horizontal surface, wherein a portion (35) of the housing accommodating at least a portion of the controller is arranged further away from the base than the aerosol generator as seen in a vertical direction, when the base is supported on the horizontal surface.

Abstract: The invention provides aqueous liquid pharmaceutical compositions comprising arbekacin and chloride ions. The compositions are well tolerable for use in a method for treatment or prevention of a disease of the upper or lower respiratory tract, wherein the composition is aerosolized and inhaled by the patient. Furthermore, the invention provides arbekacin hydrochloride.

Abstract: The present invention relates to a control device for an aerosol nebulizer, comprising: a communication unit (100), configured to establish a wireless communication connection and to perform data communication with a communication device (20); a control unit (200), configured to control an operation of the aerosol generator; a storage unit (300), configured to store in advance an identification value of said communication device (20), wherein, based on said identification value, said communication unit (100) is further configured to establish said wireless communication connection by an authentication of the communication device (20) based on the identification value of the communication device (20).

Abstract: An ampoule for insertion into an aerosol generator, in order to atomize a substance (40) contained in the ampoule, comprising: a container portion (10), which forms a chamber (11, 23) for receiving at least one constituent of the substance (40); and an interface portion (20), which is designed for receiving and fixing the ampoule receiving portion of the aerosol generator and has, in a direction in which the ampoule is intended to be inserted into the aerosol generator, a push-up bottom (15, 31), characterized in that the container portion (10) and the interface portion (20) are formed by separate parts and the interface portion is of a closable design.

Abstract: The invention relates to an aerosol delivery device (A) comprising an aerosol generator for generating an aerosol in the aerosol delivery device with a membrane (1) and a vibrator (7) which is configured to vibrate a fluid and to aerosolise the fluid by the membrane (1).

Abstract: The invention relates to a fluid reservoir (1, 100, 330, 400) which is attachable to an aerosol generation device for guiding a fluid from a fluid container (16, 116, 300) to the aerosol generation device. The fluid reservoir has an interface portion (2, 102, 202) arranged at the fluid reservoir for attaching the fluid reservoir to the aerosol generation device. The interface portion has a locking element (8, 10, 12, 14; 110, 114; 210, 214) configured to non-detachably lock the fluid reservoir to the aerosol generation device after attachment of the fluid reservoir to the aerosol generation device. The locking element is breakable to enable detachment of the fluid reservoir from the aerosol generation device. Further, the invention relates to a combination of the fluid reservoir and a primary fluid package (250), wherein the primary fluid package has at least one chamber (252, 254) containing a fluid therein.

Abstract: For use in premature babies and infants, in particular for administering surfactant to the lungs, the inhalation therapy device described herein comprises an aerosol generating device 1, a respiratory air flow generating means 3 and a nebulising chamber 5 into which the generated liquid droplets 2 and the respiratory air flow 4 are supplied. The nebulising chamber 5 comprises a tapering area 52 which ends in a tubular intubation means 6. The intubation means 6 is designed such that the intubation end 6b can be positioned in such a manner that the liquid droplet/respiratory air mixture conveyed via the intubation means is released behind those areas of the respiratory tract that filter out to a great extent the liquid droplets from the mixture.

Abstract: Disposable ampoule for use in an aerosol generating device, comprising: a medicament container that contains a medicament and is formed of a container body and a container bottom, and a predetermined break point that at least partly surrounds the container bottom, characterised by a collar that surrounds the predetermined break point at its outside and extends the container body over and beyond the container bottom.

Abstract: For use in premature babies and infants, in particular for administering surfactant to the lungs, the inhalation therapy device described herein comprises an aerosol generating device 1, a respiratory air flow generating means 3 and a nebulizing chamber 5 into which the generated liquid droplets 2 and the respiratory air flow 4 are supplied. The nebulizing chamber 5 comprises a tapering area 52 which ends in a tubular intubation means 6. The intubation means 6 is designed such that the intubation end 6b can be positioned in such a manner that the liquid droplet/respiratory air mixture conveyed via the intubation means is released behind those areas of the respiratory tract that filter out to a great extent the liquid droplets from the mixture.

Abstract: Disposable ampoule for use in an aerosol generating device, comprising: a medicament container that contains a medicament and is formed of a container body (10) and a container bottom (11), and a predetermined break point (12) that at least partly surrounds the container bottom, characterized by a collar (15) that surrounds the predetermined break point (12) at its outside and extends the container body (10) over and beyond the container bottom (11).

Abstract: Liquid aqueous pharmaceutical solutions, containing a mast cell stabilizing active agent for application to the upper and lower respiratory tract or in the eye are provided. The solutions comprise both a non-ionic and an ionic tonicity-adjusting excipient. They are particularly useful for the aerosol treatment of respiratory diseases such as asthma. Furthermore, methods for nebulization of these solutions and methods of packaging the solutions are provided.

Abstract: Atomizer for a ventilation machine with a ventilator, including a body with a first connection for connecting the atomizer to a ventilator and a second connection for connecting the atomizer to a line leading to a patient, wherein the body forms a flow channel from the first connection to the second connection; and an atomizing device for atomizing a fluid; wherein the atomizing device is disposed between the first connection and the second connection in the flow channel and adapted so that the fluid can be atomized substantially parallel to, and preferably in, the flow direction from the first connection to the second connection.

Abstract: A membrane nebulizer for producing aerosol in an aerosol therapy device includes a membrane having several through-holes for nebulizing a fluid; and a laminar carrier having an opening, the membrane being arranged in the opening and fastened to the carrier in such a way that the nebulizing occurs on a first side of the carrier and the fluid is present at the membrane on the opposite second side of the carrier, wherein the membrane is welded to the carrier by means of a resistance welding method.

Abstract: The invention relates to liquid pharmaceutical compositions containing: a) a therapeutically effective dose of a cyclosporin; b) an aqueous carrier liquid; c) a first solubilizing substance selected among the group of phospholipids; and d) a second solubilizing substance selected among the group of non-ionic surfactants. Preferably, the cyclosporin is liposome solubilized. The inventive composition is suitable for oral, parenteral, nasal, mucosal, topical, and particularly pulmonary application in the form of an aerosol.

Abstract: The invention relates to an opening element (1, 50, 50?, 80) for opening an ampoule (118) in an aerosol generation device (100). The opening element (1, 50, 50?, 80) comprises a first member (2, 82) which has a conduit (6, 86) extending therethrough for guiding a fluid (120) contained in the ampoule (118) through the first member (2, 82) and a second member (4, 52, 84) which is arranged at least partly inside or on the conduit (6, 86). Further, the invention relates to an aerosol generation device (100) comprising such an opening element (1, 50, 50?, 80).

Abstract: Atomizer for a ventilation machine with a ventilator, including a body with a first connection for connecting the atomizer to a ventilator and a second connection for connecting the atomizer to a line leading to a patient, wherein the body forms a flow channel from the first connection to the second connection; and an atomizing device for atomizing a fluid; wherein the atomizing device is disposed between the first connection and the second connection in the flow channel and adapted so that the fluid can be atomized substantially parallel to, and preferably in, the flow direction from the first connection to the second connection.

Abstract: For use in premature babies and infants, in particular for administering surfactant to the lungs, the inhalation therapy device described herein comprises an aerosol generating device 1, a respiratory air flow generating means 3 and a nebulising chamber 5 into which the generated liquid droplets 2 and the respiratory air flow 4 are supplied. The nebulising chamber 5 comprises a tapering area 52 which ends in a tubular intubation means 6. The intubation means 6 is designed such that the intubation end 6b can be positioned in such a manner that the liquid droplet/respiratory air mixture conveyed via the intubation means is released behind those areas of the respiratory tract that filter out to a great extent the liquid droplets from the mixture.