Abstract: A physical method for regulating molecular transport within a brain extracellular space includes: applying an external pressure to brain tissue of an animal, wherein a rhythm of applying the external pressure is related to intrinsic rhythmicity of the animal. An apparatus for regulating molecular transport within a brain extracellular space includes: a detection mechanism (10), a pressurization mechanism (30), and a control mechanism (50). The detection mechanism (10) is capable of detecting intrinsic rhythmicity of an animal. The pressurization mechanism (30) is capable of applying an external pressure to brain tissue of the animal. The control mechanism (50) is capable of control the pressurization mechanism (10) based on a detection result of the detection mechanism (30), such that a rhythm of applying the external pressure by the pressurization mechanism (30) is related to the intrinsic rhythmicity of the animal.

Abstract: An operating circuit and an operating method of a resistive random-access memory are provided, the operating circuit includes: at least one capacitance connected in series with the resistive random-access memory, so that the resistive random-access memory is grounded through the at least one capacitance. The operating method includes: connecting at least one capacitance in series with a resistive random-access memory, so that the resistive random-access memory is grounded through the capacitance; applying a forming pulse voltage or a set pulse voltage on the resistive random-access memory to achieve a forming operation or a set operation of the resistive random-access memory.

Abstract: An image inpainting method includes: acquiring an image to be inpainted based on depth information and texture information of a reference image, the image to be inpainted including at least one region to be inpainted; determining at least one reference block matching the at least one region to be inpainted respectively in the reference image; and inpainting the at least one region to be inpainted by using the at least one reference block to obtain a composite image.

Abstract: The present disclosure discloses a defect location method and device based on coverage information, the method including: characterizing program structure information and test case coverage information of a target program in a graph to obtain a graph-characterized structure; generating a node attribute sequence and an adjacency matrix based on the graph-characterized structure; and inputting the node attribute sequence and the adjacency matrix to a trained graph neural network model, so that the graph neural network model outputs a suspicious degree list of the target program based on the node attribute sequence and the adjacency matrix. Through the graph-based unified information characterization, the coverage information can be saved without loss and compression, and the structure information may also be considered, thereby improving the accuracy of defect location.

Abstract: A memory network method based on automatic addressing and recursive information integration. The method is based on a memory neural network framework integrating automatic addressing and recursive information, and is an efficient and lightweight memory network method. A memory is read and written by means of an automatic addressing operation having low time and space complexity, and memory information is effectively utilized by a novel computing unit. The whole framework has the characteristics of high efficiency, high speed and high universality. The method is suitable for various time sequence processing tasks, and shows the performance superior to that of the conventional LSTM and the previous memory network.

Abstract: The present disclosure provides a complementary phototransistor pixel unit, a sensing and computing array structure and an operation method thereof. The complementary phototransistor pixel unit includes: a first photoelectric field effect transistor, which is a photoelectric field effect transistor based on an ultra-thin body and buried oxide layer; and a second photoelectric field effect transistor, the second photoelectric field effect transistor is a photoelectric field effect transistor based on an ultra-thin body and buried oxide layer, each of the first photoelectric field effect transistor and the second photoelectric field effect transistor is four-end device and has a gate electrode G, a source electrode S, a drain electrode D, and a well base electrode B, and the source electrode S or drain electrode D of the first photoelectric field effect transistor is connected to the source electrode S or drain electrode D of the second photoelectric field effect transistor.

Abstract: The present disclosure discloses a conflict detection method for Internet of Things (IoT) device scheduling, relating to the technical field of the IoT, and specific steps include: acquiring data of a device model; converting a device scheduling instruction into a conditional instruction according to the data of the device model; determining a scheduling conflict rule according to device scheduling conflicts in historical data; detecting whether the conditional instruction is in a conflict state based on the scheduling conflict rule; if the conditional instruction is in a conflict state, performing a first conflict resolution, or if the conditional instruction is in a non-conflict state or after a conflict is resolved, performing a second detection; converting, in the second detection, the conditional instruction into an SMT formula, inputting the SMT formula into an SMT solver for detection, and determining whether the conditional instruction is in a conflict state; and if the conditional instruction is in a

Abstract: A direct structured illumination microscopy (dSIM) reconstruction method is provided. First, a time domain modulation signal is extracted through a wavelet. Then, an incoherent signal is converted into a coherent signal. Next, an accumulation amount at each pixel is calculated. Finally, a super-resolution image is generated by using a correlation between signals at different spatial positions. An autocorrelation algorithm of dSIM is insensitive to an error of a reconstruction parameter. dSIM bypasses a complex frequency domain operation in structured illumination microscopy (SIM) image reconstruction, and prevents an artifact caused by the parameter error in the frequency domain operation. The dSIM algorithm has high adaptability and can be used in laboratory SIM, nonlinear SIM imaging systems, or commercial systems.

Abstract: Provided are circular RNAs (circRNAs) encoding an antigenic polypeptide of a SARS-CoV-2 variant. Provided are circRNA vaccines against a SARS-CoV-2 variant, such as a Delta or Omicron variant. The circRNA vaccine comprises a circRNA comprising a nucleic acid sequence encoding an antigenic polypeptide comprising a Spike(S) protein or a fragment thereof of a SRAS-CoV-2 variant. Also provided are methods of treating or preventing a SARS-CoV-2 infection using the circRNAs or compositions thereof.

Abstract: An expanding and shaping device for cervical spinal canal and a mounting device are provided, including the first fixing part, the second fixing part, and the fasteners. The passing-through direction of the fasteners is consistent with the direction of the incision. The fasteners are nailed along a coronal surface. The fasteners pass through the second fixing hole to connect the lateral mass.

Abstract: Embodiments of the present application provides a method for improving the short-circuit capability of an enhancement-mode (E-mode) GaN HEMT and its device structure. This is achieved by depositing metal in the active region between the gate and the source, adjacent to the source region of a conventional E-mode GaN HEMT, the metal is directly connected with the source of the conventional E-mode GaN HEMT. The conventional E-mode GaN HEMT is combined with a gate-source-shorted depletion-mode (D-mode) GaN HEMT to form a complete E-mode GaN HEMT with improved short-circuit capability. By clamping the saturation current of the complete device through the D-mode GaN HEMT, the saturation current density of the E-mode GaN HEMT can be reduced, and the purpose of improving the short-circuit capability is finally realized.

Abstract: The present disclosure provides a method and an apparatus for operating an in-memory computing architecture applied to a neural network and a device, the method includes: generating a mono-pulse input signal based on discrete time coding; inputting the mono-pulse input signal into a memory array of the in-memory computing architecture to generate a bit line current signal corresponding to the memory array; and controlling a neuron circuit of the in-memory computing architecture to output a mono-pulse output signal based on discrete time coding according to the bit line current signal, wherein the mono-pulse output signal is configured as a mono-pulse input signal of a memory array of the next layer of neural network in the next in-memory computing cycle.

Abstract: The present disclosure provides a cell segmentation and typing method, device, apparatus and medium based on machine learning. The method includes: acquiring at least one cell metabolism image of a target object; performing single cell image segmentation on the at least one cell metabolism image by using a machine learning segmentation model to obtain a plurality of single cell metabolism images; performing single cell feature extraction on each single cell metabolism image of the plurality of single cell metabolism images to obtain a single cell image feature map corresponding to the single cell metabolism image; combining the single cell image feature map corresponding to each single cell metabolism image of the plurality of single cell metabolism images to obtain an image feature map of the target object; performing typing of the cell by clustering the image feature map of the target object.

Abstract: An intelligent deformable microneedle includes a supporting seat; a counter electrode provided above the supporting seat; an elastic object with a compressed state and a natural state, where a working electrode is provided on an outer surface of the elastic object, and a specific enzyme that can react with an analyte to be detected is provided on the working electrode; a soluble needle-shaped body fixed on the supporting seat, where the soluble needle-shaped body completely wraps the counter electrode and the elastic object from the outside, and the soluble needle-shaped body has an inner cavity structure that enables the elastic object to be in the compressed state. The microneedle is internally provided with the elastic object, after penetrating into skin, the soluble needle-shaped body is dissolved, the elastic object inside is exposed, length becomes longer, and the working electrode of an electrochemical sensor is attached to the elastic object.

Abstract: A nonlinear optical crystal structure is provided. The nonlinear optical crystal structure includes a plurality of two-dimensional material films, wherein the plurality of two-dimensional material films are stacked in a direction perpendicular to a two-dimensional plane thereof, and two-dimensional material films adjacent to each other are bonded by van der Waals forces, each of the plurality of two-dimensional material films is a crystal with a center-inversion-asymmetric crystal structure, and has a predetermined lattice orientation parallel to the two-dimensional plane in a direction parallel to the two-dimensional plane, there is a non-zero twist angle between the two-dimensional material films adjacent to each other, and the twist angle is an included angle between predetermined lattice orientations of the two-dimensional material films adjacent to each other in the same two-dimensional plane, and a thickness of each of the plurality of two-dimensional material films is greater than 5 nm.

Abstract: The present application discloses a UTBB photodetector pixel unit, array and method, including: a silicon film layer, a buried oxide layer, a charge collection layer and a substrate, the silicon film layer, the buried oxide layer, the charge collection layer and the substrate being arranged in sequence from top to bottom; the silicon film layer includes NMOS transistors or PMOS transistors; the charge collection layer includes charge collection control regions and charge accumulation regions; and the substrate includes an N-type substrate or a P-type substrate. A centripetal electric field is formed around the charge accumulation regions, and photo-generated charges are accumulated in the corresponding pixel units under the action of the centripetal electric field.

Abstract: The present invention pertains to pharmaceutical chemical field, and relates to a sterol derivative as well as preparation method and uses thereof. Specifically, the present invention relates to a compound of Formula I, or a pharmaceutically acceptable salt, ester or ether thereof, wherein, R1 is selected from the group consisting of —OH, ?O(carbonyl), H, and C1-C3 alkyl; R2 is selected from the group consisting of —OH, H, and C1-C3 alkyl; R3 is selected from the group consisting of —OH, ?O, H, and C1-C3 alkyl; R4 is selected from the group consisting of —OH, H, and C1-C3 alkyl; and none, one, two, three or four of R1, R2, R3, and R4 are —OH. The compound of the present invention can inhibit HMG-CoA reductase, tumor cells and lipase effectively, and is a potential drug for reducing blood-fat, antitumors, or for losing weight.

Abstract: A root canal treatment robot and a treatment method using the same. In the robot, a pan tilt, and a working optical fiber are driven by an x-axis movement unit and a y-axis movement unit to move on the x-y plane, and the working optical fiber is further driven by a z-axis movement unit to move along the z-axis, and driven by an a-axis movement unit to rotate around the z-axis.

Abstract: A processing method of a flexible hybrid electronic system is provided and includes the following steps: etching out embedded grooves on a front surface of a silicon-based substrate embedding a plurality of heterogeneous chips into corresponding embedded grooves, wherein front surfaces of the embedded chips are flush with the front surface of the silicon-based substrate; then gradually realize the polymer flexible connection, electrical interconnection, insulation protection, and polymer flexible coverage between chips. The processing method processes the flexible hybrid electronic system based on the method of embedding chips, which can reduce material loss and processing steps, and is beneficial to realizing large-scale manufacturing.

Abstract: The present invention discloses a method for enhancing the activity of a photosensitizer by a magnetic field, in which the photosensitizer is placed in the magnetic field under light conditions, thus improving the cytotoxicity of the photosensitizer to tumor cells and increasing the activity of the photosensitizer, thereby further enhancing the apoptosis of cancer cells or an inhibitory effect on tumor tissue by using photodynamic treatment methods, which helps to improve an effect of photodynamic therapy.