Patents Assigned to Peking University
  • Publication number: 20240384433
    Abstract: The present invention provides a method for scalable fabrication of ultra-flat polycrystalline diamond membranes, the method comprising: (1) performing chemical vapor deposition on a growth substrate having diamond seeds thereon to grow a polycrystalline diamond membrane, wherein an exposed surface of the polycrystalline diamond membrane is a grown surface having a first roughness; and a surface bonded to the growth substrate is a buried surface; (2) bonding the grown surface to a transfer substrate using an adhesive; and (3) removing the growth substrate to expose the buried surface of the polycrystalline diamond membrane, wherein the buried surface has a second roughness after exposure, and the second roughness is less than the first roughness.
    Type: Application
    Filed: May 14, 2024
    Publication date: November 21, 2024
    Applicants: The University of Hong Kong, Dongguan Institute of Opto-electronics, Peking University, Southern University of Science and Technology
    Inventors: Zhiqin CHU, Jixiang Jing, Qi WANG, Zhongqiang WANG, Kwai Hei LI
  • Patent number: 12144543
    Abstract: Provided are a controllably self-deformable optical fiber, a multifunctional laser scalpel and a laser processing device including the same. The controllably self-deformable optical fiber drives the protective layer and the optical fiber to deform through controllable deformation of a deformation portion on an outer surface of the protective layer. In addition, the optical fiber also has multiple functions, and can be applied in the treatment of complex lacunae in medical and other related fields.
    Type: Grant
    Filed: March 7, 2021
    Date of Patent: November 19, 2024
    Assignee: Peking University School of Stomatology
    Inventors: Fusong Yuan, Peijun Lyu, Shanshan Liang
  • Patent number: 12126523
    Abstract: This application provides a method for multiplexing HTTP channels. The method includes: sending, by the terminal, a first HTTP request to a first server through a first HTTP channel, to request first data; after receiving a first HTTP response returned by the first server, receiving, through the first HTTP channel, a first part that is of the first data and that is sent by the first server; and if a size that is of the first data and that is carried in the first HTTP response is greater than a first threshold, generating a second HTTP request, and sending a second HTTP request to a second server through a second HTTP channel, to request a second part of the first data; and after receiving the first part of the first data, sending control signaling to the first server, to disconnect the first HTTP channel.
    Type: Grant
    Filed: June 13, 2022
    Date of Patent: October 22, 2024
    Assignees: Huawei Technologies Co., Ltd., Peking University
    Inventors: Hao Wang, Zheng Hu, Chenren Xu, Shuo Chen, Xingmin Guo, Xiaojin Li
  • Patent number: 12120331
    Abstract: A system and a method for compressing an image based on a FLASH in-memory computing array are provided. The system includes: a convolutional neural network for encoding of the FLASH in-memory computing array, a convolutional neural network for decoding based on the FLASH in-memory computing array, and a quantization module; the convolutional neural network for encoding based on the FLASH in-memory computing array is configured to encode an original image to obtain a feature image; the quantization module is configured to quantize the feature image to obtain a quantized image; the convolutional neural network for decoding based on the FLASH in-memory computing array is configured to decode the quantized image to obtain a compressed image.
    Type: Grant
    Filed: December 31, 2019
    Date of Patent: October 15, 2024
    Assignee: Peking University
    Inventors: Jinfeng Kang, Yachen Xiang, Peng Huang, Xiaoyan Liu, Runze Han
  • Publication number: 20240319129
    Abstract: A methane sensor includes a substrate, a conductive connection electrode, and a sensing electrode, the conductive connection electrode is arranged on the substrate, and the sensing electrode is covered on the conductive connection electrode, the sensing electrode is a layer of conductive polymer film, and the conductive connection electrode is coated with an insulating layer in addition to the sensing area. The sensing electrode adopts one of poly (3,4-ethylenedioxythiophene): poly (styrene sulfonic acid), polyaniline, polythiophene and polypyrrole, which is made into a film by a screen printing, inkjet printing or other coating method in the form of liquid or paste. The present invention adopts the above methane sensor, with a small and stable sensor, realizing sensitive and rapid detection of methane, and solving the problems of high power consumption of methane sensors in the prior art, high working temperature, expensive and bulky casing of the equipment, and high price.
    Type: Application
    Filed: December 25, 2023
    Publication date: September 26, 2024
    Applicant: Peking University
    Inventor: Yue CUI
  • Publication number: 20240319181
    Abstract: A chemiluminescent lateral flow immunoassay method is provided for reducing cross reactions and false positives when detecting protein analytes. The detection method involves a lateral flow immunoassay strip, the strip includes a sample pad, a conjugate pad, a nitrocellulose membrane, and an absorbent pad. The capture antibody of the analyte on the nitrocellulose membrane is used as the test line, and the IgG antibody is used as the control line. The lateral flow immunoassay is performed on the strip by the Au nanoparticle-antibody-horseradish peroxidase-polyethylene glycol (AuNP-Ab-RP-PEG) conjugate to detect the specific analyte. During the detection, the conjugate is prepared in the strip and then added to the analyte for detection, or the conjugate is mixed with the analyte and then added to the strip for detection.
    Type: Application
    Filed: December 21, 2023
    Publication date: September 26, 2024
    Applicant: Peking University
    Inventor: Yue CUI
  • Publication number: 20240302638
    Abstract: Disclosed are an optical instrument, an imaging system, and an imaging method for a miniature multi-photon microscope, relating to the optical configuration field. The optical instrument is configured to have a fluorescence excitation optical path and a fluorescence collection optical path. The optical instrument includes a condenser, and the condenser includes a first lens group and a second lens group separately disposed. The first lens group is located in the fluorescence collection optical path, the second lens group is located in the fluorescence excitation optical path and the fluorescence collection optical path. A relative distance the second lens group and a miniature objective is less than a first preset distance threshold. A collection efficiency of scattered fluorescence of the miniature multi-photon microscope may be improved, thereby improving an imaging signal-to-noise ratio and an imaging depth when a sample to be test with a scattering characteristic is observed.
    Type: Application
    Filed: May 17, 2024
    Publication date: September 12, 2024
    Applicants: Beijing Transcend Vivoscope Bio-Technology Co., Ltd., Peking University
    Inventors: Chunzhu ZHAO, Aimin WANG, Heping CHENG
  • Publication number: 20240303957
    Abstract: Provided in the present application are an end-edge-cloud coordination system and method based on a digital retina, and a device. The coordination system may include, but is not limited to, a front-end device, an edge device, and a cloud device. The front-end device is used for extracting, from collected video data, features having universality, and is used for generating analysis and recognition tasks on the basis of the features. The front-end device is also used for processing the analysis and recognition tasks, so as to obtain a first intermediate result to be sent to the edge device. The edge device is used for processing the analysis and recognition tasks on the basis of the first intermediate result, so as to obtain a second intermediate result to be sent to the cloud device. The cloud device is used for processing the analysis and recognition tasks on the basis of the second intermediate result, so as to obtain an analysis and recognition result for video data.
    Type: Application
    Filed: April 12, 2021
    Publication date: September 12, 2024
    Applicant: Peking University
    Inventors: Yonghong TIAN, Peiyin XING, Feng GAO, Xiaofei LIU, Peixi PENG, Wen GAO
  • Patent number: 12081298
    Abstract: A method and a system are for non-contact determination of a detection boundary. A Wi-Fi receiving device simultaneously receives data packets by using any two antennas, and measures channel state information; conjugate multiplication is performed on the CSI measured at a moment corresponding to reception of the two antennas, to obtain a new CSI signal stream; a time window with the length M is selected from the new CSI signal stream, and M CSI samples in the time window are collected, to form a conjugate set; the mean of the conjugate set is subtracted from all the samples in the conjugate set, to obtain a zero-mean conjugate set; N zero-mean conjugate sets are obtained for CSI on N sub-carriers simultaneously transmitted; and probability distribution fitting is performed on the absolute values of all elements in the N zero-mean conjugate sets, to calculate a boundary detection feature.
    Type: Grant
    Filed: June 10, 2021
    Date of Patent: September 3, 2024
    Assignee: Peking University
    Inventors: Daqing Zhang, Shengjie Li
  • Publication number: 20240287013
    Abstract: A method for asymmetric synthesis of (?)-Anisomelic Acid is provided in the present invention, a chiral compound (?)-Costunolide is used as a starting material, a key intermediate is obtained by a regioselective ozone decomposition reaction, then carbon chain extension is performed by a Horner-Wadsworth-Emmons (HWE) reaction and a Peterson olefination reaction, and a (?)-anisomelic acid fourteen-membered carbocyclic skeleton is constructed by a ring-closing metathesis (RCM) reaction, laying an important foundation for subsequent (?)-anisomelic acid biological activity research, in the synthesis route, various (?)-anisomelic acid analogs can also be obtained from the key intermediate, the reaction operations in the synthesis route are simple and the present invention can be widely popularized and used.
    Type: Application
    Filed: June 10, 2021
    Publication date: August 29, 2024
    Applicants: Peking University Shenzhen Graduate School, CNS BIOTEK CORP., Gansu Evergreen Pharmaceuticals Co.,Ltd.
    Inventors: Zhen Yang, Yew-Min Tzeng, Hai-Xin Yu, Nan Zheng, Chong-Guo Jiang
  • Publication number: 20240279062
    Abstract: The present disclosure provides a method and a system for efficient and selective recovery of a ferric phosphate product from a leachate. The method includes the following steps: adjusting a pH value of a phosphorus-containing leachate to obtain an acidic phosphorus-containing leachate, heating the acidic phosphorus-containing leachate, adding an iron salt to precipitate a phosphorus element in the acidic phosphorus-containing leachate in the form of a ferric phosphate hydrate, and recovering an obtained ferric phosphate hydrate precipitate. In the present disclosure, production of a phosphorus product requires a certain amount of iron element added into the leachate. Iron widely distributed on the earth is low in cost and easily available, thereby facilitating large-scale applications of the method. An initial leachate after acid leaching shows acidic, and only a slight pH adjustment is required to achieve a target pH value of the leachate.
    Type: Application
    Filed: February 21, 2024
    Publication date: August 22, 2024
    Applicant: Peking University
    Inventors: Wulin Yang, Shaogang Hu
  • Patent number: 12066443
    Abstract: The invention relates to a method for prognosing ACS in a subject, the method comprising determining plasma MIF and Nt-proBNP (or BNP) concentrations in a sample from the subject, diagnosing ACS when the subject plasma concentrations are greater than a reference MIF and Nt-proBNP (or BNP) plasma concentration, and prognosing the magnitude of ACS from the subject plasma MIF and Nt-proBNP (or BNP) concentrations. Also provided is a method of treating ACS in a subject, a device, a kit, and a cardiac biomarker related to the methods of prognosing ACS.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: August 20, 2024
    Assignees: Alfred Health, Peking University Third Hospital
    Inventors: Anthony Dart, Wei Gao
  • Publication number: 20240274748
    Abstract: Disclosed is a method for preparing a nitride light emitting diode (LED) and nondestructive interface separation. A two-dimensional atomic crystal layer on a transparent substrate is modified by using an atomic irradiation technology, to obtain an irradiated region; a nitride LED structure is prepared on a modified two-dimensional atomic crystal layer, and a support substrate is cured by means of a metal functional layer; visible laser is incident from a back surface of the transparent substrate to directionally destruct the irradiated region of the two-dimensional atomic crystal layer, so as to obtain a whole structure of the nitride LED structure, the metal functional layer and the support substrate that are separated from the transparent substrate. The present disclosure can nondestructively separate the interface and repeatedly use the transparent substrate.
    Type: Application
    Filed: August 9, 2022
    Publication date: August 15, 2024
    Applicant: Peking University
    Inventors: Xinqiang Wang, Fang Liu, Zhaoying Chen, Yucheng Guo, Bowen Sheng, Duo Li, Bo Shen
  • Publication number: 20240273274
    Abstract: A method of establishing a transistor statistical model based on an artificial neural network system comprising receiving a first data set and generating a nominal model of a baseline transistor by the artificial neural network system based on the first data set; screening neurons in the artificial neural network system based on the first data set and the nominal model to obtain final variational neurons; obtaining distribution of weights of the final variational neurons and distribution of threshold voltages based on variation of the nominal model with respect to weights of the final variational neurons, variation of the nominal model with respect to the threshold voltages, distribution of the drain-source current and distribution of the gate-source voltage in the first data set; and establishing the transistor statistical model based on the nominal model, the distribution of weights of the final variational neurons and the distribution of the threshold voltages.
    Type: Application
    Filed: January 31, 2024
    Publication date: August 15, 2024
    Applicant: Peking University Shenzhen Graduate School
    Inventors: Lining ZHANG, Wu DAI, Yu LI, Runsheng WANG, Ru HUANG
  • Publication number: 20240266254
    Abstract: The present invention relates to a wire bonding structure with an embedded manifold type micro-channel. The wire bonding structure includes: a chip, including a substrate and an embedded micro-channel located on a back portion of the substrate; an interposer, including a manifold channel, a liquid inlet, and a liquid outlet; a low-temperature sealing layer, configured to hermetically communicate the embedded micro-channel with the manifold channel, wherein the low-temperature sealing layer is located between the chip and the interposer; and a bonding wire, configured to electrically connect the chip to the interposer. The present invention further relates to a preparation method of a wire bonding structure with an embedded manifold type micro-channel. The wire bonding structure of the present invention has both low-temperature process compatibility and packaging compatibility, and further has high heat dissipation efficiency.
    Type: Application
    Filed: June 1, 2021
    Publication date: August 8, 2024
    Applicant: Peking University
    Inventors: Wei WANG, Yuchi YANG, Jianyu DU
  • Patent number: 12051220
    Abstract: Provided are a point cloud attribute prediction method and prediction device based on a filter. The method comprises a coding method and a decoding method, and the device comprises a coding device and a decoding device. The method comprises: determining K nearest neighbor points of the current point; determining a filter matrix; and determining an attribute prediction value of the current point according to the filter matrix. Therefore, the compression performance of a point cloud attribute can be improved by means of selecting an appropriate filter.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: July 30, 2024
    Assignee: Peking University Shenzhen Graduate School
    Inventors: Ge Li, Chuang Ma, Jing Wang, Yi Ting Shao, Wen Gao
  • Publication number: 20240247265
    Abstract: The present application provides linear RNA precursors and constructs for preparing circular RNAs (circRNAs) comprising an effector RNA sequence, such as a coding RNA sequence. In some embodiments, the linear RNA comprises from the 5? end to the 3? end: (a) a first portion of an RNA element (e.g., an IRES), (b) an effector RNA sequence, and (c) a second portion of the RNA element, wherein the first and the second portions of the RNA element associate with each other to form a double-stranded region of at least 4 basepairs long, wherein the 5? end of the first portion of the RNA element and the 3? end of the second portion of the RNA element form a nick in the double-stranded region, and wherein an RNA ligase can ligate the nick. Also provided are methods of preparing circRNAs, circRNAs prepared thereof, and methods of using the circRNAs.
    Type: Application
    Filed: February 26, 2024
    Publication date: July 25, 2024
    Applicant: Peking University
    Inventors: Wensheng WEI, Zongyi YI
  • Publication number: 20240241696
    Abstract: A random number generator includes: a random number generating circuit used for generating a pulse signal based on a control word and generating a random number signal according to the pulse signal, the pulse signal including a first frequency signal and a second frequency signal that appear alternately, and proportions of the first frequency signal and the second frequency signal being controlled by the control word; and a feedback update circuit used for updating the control word based on the random number signal output by the random number generating circuit.
    Type: Application
    Filed: October 27, 2021
    Publication date: July 18, 2024
    Applicants: BOE TECHNOLOGY GROUP CO., LTD., Peking University
    Inventors: Xiangye WEI, Ming ZHAO, Wei HU, Yimao CAI, Shengyi HE, Yiming BAI, Xinyu ZHOU
  • Publication number: 20240240311
    Abstract: The present invention provides a scalable method for achieving shape control of diamond micro-nanoparticles, comprising air oxidizing diamond micro-nanoparticles grown by chemical vapor deposition and/or diamond micro-nanoparticles grown by high pressure and high temperature. The present invention achieves the controllable morphology transformation of diamond micro-nanoparticles via air oxidation treatment. It has been demonstrated that a series of unique shapes, including “flower” shaped, “hollow” structured, “pyramid” patterned on the surface, and “boomerang” shaped, can be achieved by altering the air oxidation parameters, i.e., temperature and duration. The scalable production of these differently shaped diamond micro-nanoparticles represents a significant scientific breakthrough together with a high commercial value.
    Type: Application
    Filed: January 18, 2024
    Publication date: July 18, 2024
    Applicants: Versitech Limited, Southern University of Science and Technology, Dongguan Institute of Opto-electronics, Peking University
    Inventors: Zhiqin CHU, Tongtong ZHANG, Qi WANG, Zhongqiang WANG, Kwai Hei LI
  • Patent number: 12039440
    Abstract: An image classification method and apparatus, and an image classification model training method and apparatus are provided, which are related to an image recognition technology in the artificial intelligence field and more specifically, to the computer vision field. The method includes: obtaining a to-be-processed image; and classifying the to-be-processed image based on a preset global class feature, to obtain a classification result of the to-be-processed image. The preset global class feature includes a plurality of class features obtained through training based on a plurality of training images in a training set. The plurality of class features in the preset global class feature are used to indicate visual features of all classes in the training set.
    Type: Grant
    Filed: January 24, 2022
    Date of Patent: July 16, 2024
    Assignees: Huawei Technologies Co., Ltd., Peking University
    Inventors: Weiran Huang, Aoxue Li, Zhenguo Li, Tiange Luo, Liwei Wang