Patents Assigned to Pharmaceutical Solutions, Inc.
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Patent number: 8784865Abstract: This invention is related to the use of polyurethane-based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs.Type: GrantFiled: May 13, 2013Date of Patent: July 22, 2014Assignee: Endo Pharmaceuticals Solutions Inc.Inventors: Petr Kuzma, Harry Quandt
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Publication number: 20140135684Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: ApplicationFiled: January 20, 2014Publication date: May 15, 2014Applicant: Endo Pharmaceuticals Solutions Inc.Inventors: Sheng-hung Kuo, Petr Kuzma
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Patent number: 8658195Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: GrantFiled: July 26, 2013Date of Patent: February 25, 2014Assignee: Endo Pharmaceuticals Solutions Inc.Inventors: Sheng-hung Kuo, Petr Kuzma
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Patent number: 8618127Abstract: Methods of treating stuttering include treating people with gamma-aminobutyric acid (GABA) receptor modulators, including cyclopyrrolones. A second active agent may be used with GABA receptor modulators. Active enantiomers, active metabolites, and pharmaceutically acceptable salts of gamma-aminobutyric acid receptor modulators, including cyclopyrrolones, are acceptable components of the compositions. The cyclopyrrolone class of modulators includes pagoclone, suriclone, zopiclone, 2-(7-chloro-2-naphthyridin-1,8-yl)-3-(5-methyl-2-oxohexyl)isoindolin-1-one, 2-(7-chloro-2-naphthyridin-1,8-yl)isoindolin-1-yl-4-acetamidobutyrate, and 2-(7-chloro-1,8-naphthyridin-2yl)-3-(5-methyl-5-hydroxy-2-oxohexyl)-1-isoindolinone.Type: GrantFiled: June 6, 2012Date of Patent: December 31, 2013Assignee: Endo Pharmaceuticals Solutions Inc.Inventors: John J. Murphy, Kay Jorgenson D'Orlando
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Patent number: 8604086Abstract: The present invention relates to a method of treating and preventing a papillomavirus infection in an individual, comprising administering to the individual a therapeutically effective amount of a condensation polymer of an aromatic sulfonic acid and an aldehyde, or a pharmaceutically acceptable salt thereof.Type: GrantFiled: February 26, 2009Date of Patent: December 10, 2013Assignee: Endo Pharmaceuticals Solutions Inc.Inventor: Albert T. Profy
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Publication number: 20130310740Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: ApplicationFiled: July 26, 2013Publication date: November 21, 2013Applicant: Endo Pharmaceuticals Solutions Inc.Inventors: Sheng-hung KUO, Petr Kuzma
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Publication number: 20130302397Abstract: This invention is related to the use of polyurethane-based polymer as a drug delivery device to deliver biologically active histrelin at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of histrelin to tissues or organs.Type: ApplicationFiled: April 22, 2013Publication date: November 14, 2013Applicant: Endo Pharmaceuticals Solutions Inc.Inventors: Petr Kuzma, Harry Quandt
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Patent number: 8566189Abstract: A computer-enabled method and system for generating a script for veterinary pharmaceutical and other animal-related product transactions comprising aggregation of participant data, including animal hospital data, veterinarian data, client data and animal data into the script, adding treatment regimen data to one or more orders associated with the script in accordance with the veterinarian's treatment plan, to enable determination of the initial date to begin filling the product, quantity of product, the number of fills and frequency to enable automatic generation of a series of autoship records including projected dates for shipping the orders to the animal owner upon verification of funds available, to print usage instructions, Rx labels, product information, shipping labels and packing slips, and to send notification emails to the animal owner and confirmation emails to the animal hospital.Type: GrantFiled: February 10, 2010Date of Patent: October 22, 2013Assignee: Strategic Pharmaceutical Solutions, Inc.Inventors: Donald C. Sutter, Kurt D. Green, Thomas A. Friar, Andrew J. Bane, Sara C. Davis
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Publication number: 20130259934Abstract: A method of treating the symptoms of spasticity comprises implanting a reservoir-based drug delivery composition into a subject to systemically deliver a therapeutically effective amount of tizanidine to the subject for a long period of time (e.g., one month or one year). The drug delivery composition may include a rate-controlling excipient (e.g., an elastomeric polymer) defining a reservoir containing at least one discrete solid dosage form (e.g., one or more pellets), which includes tizanidine free base and optionally, a sorption enhancer.Type: ApplicationFiled: May 22, 2013Publication date: October 3, 2013Applicant: Endo Pharmaceuticals Solutions Inc.Inventor: Alexander SCHWARZ
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Publication number: 20130252894Abstract: Described herein are implantable devices, formulations and methods of making implantable devices for the release of a polypeptide from an implantable device, and methods of use thereof.Type: ApplicationFiled: May 20, 2013Publication date: September 26, 2013Applicant: Endo Pharmaceuticals Solutions Inc.Inventors: Petr Kuzma, Stefanie Decker, Harry Quandt
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Patent number: 8529936Abstract: This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.Type: GrantFiled: December 4, 2012Date of Patent: September 10, 2013Assignee: Endo Pharmaceuticals Solutions Inc.Inventors: Sheng-hung Kuo, Petr Kuzma
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Patent number: 8507432Abstract: A formulation of octreotide or pharmaceutically acceptable salts thereof, which provides controlled release of a therapeutically effective amount of octreotide for a period of at least about two months. Methods of treating acromegaly, decreasing growth hormone, decreasing IGF-1, and treating conditions associated with carcinoid tumors and VIPomas by administering a controlled release formulation of octreotide are provided herein.Type: GrantFiled: June 11, 2010Date of Patent: August 13, 2013Assignee: Endo Pharmaceuticals Solutions Inc.Inventors: Petr Kuzma, Stephanie Decker
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Patent number: 8475820Abstract: Described herein are implantable devices, formulations and methods of making implantable devices for the release of a polypeptide from an implantable device, and methods of use thereof.Type: GrantFiled: July 27, 2010Date of Patent: July 2, 2013Assignee: Endo Pharmaceuticals Solutions Inc.Inventors: Petr Kuzma, Stefanie Decker, Harry Quandt
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Patent number: 8460274Abstract: This invention is related to the use of polyurethane-based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs.Type: GrantFiled: March 9, 2012Date of Patent: June 11, 2013Assignee: Endo Pharmaceuticals Solutions Inc.Inventors: Petr Kuzma, Harry Quandt
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Publication number: 20130144250Abstract: A method of treatment, such as treating an estrogen-related disorder or a psychotic disorder, by implanting a reservoir-based drug delivery composition into a subject to systemically deliver a therapeutically effective amount of an active pharmaceutical ingredient (such as an aromatase inhibitor or risperidone) to the subject for a long period of time (e.g., one month or one year). The drug delivery composition may include a rate-controlling excipient (e.g., an elastomeric polymer) defining a reservoir containing at least one discrete solid dosage form (e.g., one or more pellets), which includes an active pharmaceutical ingredient and optionally, a sorption enhancer.Type: ApplicationFiled: October 24, 2012Publication date: June 6, 2013Applicant: Endo Pharmaceuticals Solutions Inc.Inventor: Endo Pharmaceuticals Solutions Inc.
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Patent number: 8452670Abstract: A computer-enabled method for efficiently displaying automatically generated, customizable views of a master product item catalog of veterinary pharmaceutical and other animal-related product item records provided by a centralized pharmacy to a large number of veterinarians, veterinary hospitals and customers, the views comprising administrator views, hospital staff views and user views, the views being selectively excludable and modifiable by each hospital administrator via an exception-type customization and hospital manageable database, access to which is provided for each hospital on the central pharmacy's server, each hospital being enabled to provide customers and staff of the hospital access to its customized catalog via point-of-sale and e-commerce points of access over the Internet or other network.Type: GrantFiled: February 8, 2011Date of Patent: May 28, 2013Assignee: Strategic Pharmaceutical Solutions, Inc.Inventors: Donald C. Sutter, Kurt D. Green, Thomas A. Friar, Andrew J. Bane
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Publication number: 20130115264Abstract: A method of treating the symptoms of Parkinson's disease comprises implanting a reservoir-based drug delivery composition into a subject to systemically deliver a therapeutically effective amount of rasagiline to the subject for a long period of time (e.g., one month or one year). The drug delivery composition may include a rate-controlling excipient (e.g., an elastomeric polymer) defining a reservoir containing at least one discrete solid dosage form (e.g., one or more pellets), which includes rasagiline hemitartrate and optionally, a sorption enhancer.Type: ApplicationFiled: October 24, 2012Publication date: May 9, 2013Applicant: Endo Pharmaceuticals Solutions Inc.Inventor: Endo Pharmaceuticals Solutions Inc.
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Publication number: 20130108680Abstract: A method of treating the symptoms of spasticity comprises implanting a reservoir-based drug delivery composition into a subject to systemically deliver a therapeutically effective amount of tizanidine to the subject for a long period of time (e.g., one month or one year). The drug delivery composition may include a rate-controlling excipient (e.g., an elastomeric polymer) defining a reservoir containing at least one discrete solid dosage form (e.g., one or more pellets), which includes tizanidine free base and optionally, a sorption enhancer.Type: ApplicationFiled: October 24, 2012Publication date: May 2, 2013Applicant: Endo Pharmaceuticals Solutions IncInventor: Endo Pharmaceuticals Solutions Inc
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Patent number: D698919Type: GrantFiled: October 24, 2012Date of Patent: February 4, 2014Assignee: Endo Pharmaceuticals Solutions Inc.Inventors: Alexander Schwarz, Richard Caizza
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Patent number: D708324Type: GrantFiled: October 24, 2012Date of Patent: July 1, 2014Assignee: Endo Pharmaceuticals Solutions, Inc.Inventors: Alexander Schwarz, Richard Caizza