Patents Assigned to Photogen, Inc.
  • Method for improved selectivity in photo-activation of molecular agents
    Patent number: 5998597
    Abstract: A method for the treatment of a particular volume of plant or animal tissue comprising the steps of treating the plant or animal tissue with at least one photo-active molecular agent, wherein the particular volume of the plant or animal tissue retains at least a portion of the at least one photo-active molecular agent, and then treating the particular volume of the plant or animal tissue with light sufficient to promote a simultaneous two-photon excitation of at least one of the at least one photo-active molecular agent retained in the particular volume of the plant or animal tissue, wherein the at least one photo-active molecular agent becomes active in the particular volume of the plant or animal tissue. There is also disclosed a method for the treatment of cancer in plant or animal tissue and a method for producing at least one photo-activated molecular agent in a particular volume of a material.
    Type: Grant
    Filed: December 11, 1997
    Date of Patent: December 7, 1999
    Assignee: Photogen, Inc.
    Inventors: Walter G. Fisher, Eric A. Wachter, H. Craig Dees
  • Method for improved selectivity in photo-activation and detection of molecular diagnostic agents
    Patent number: 5832931
    Abstract: A method for the imaging of a particular volume of plant or animal tissue, wherein the plant or animal tissue contains at least one photo-active molecular agent. The method includes the steps of treating the particular volume of the plant or animal tissue with light sufficient to promote a simultaneous two-photon excitation of the photo-active molecular agent contained in the particular volume of the plant or animal tissue, photo-activating at least one of the at least one photo-active molecular agent in the particular volume of the plant or animal tissue, thereby producing at least one photo-activated molecular agent, wherein the at least one photo-activated molecular agent emits energy, detecting the energy emitted by the at least one photo-activated molecular agent, and producing a detected energy signal which is characteristic of the particular volume of plant or animal tissue.
    Type: Grant
    Filed: October 30, 1996
    Date of Patent: November 10, 1998
    Assignee: Photogen, Inc.
    Inventors: Eric A. Wachter, Walter G. Fisher, H. Craig Dees
  • Method for improved selectivity in photo-activation of molecular agents
    Patent number: 5829448
    Abstract: A method for the treatment of a particular volume of plant or animal tissue comprising the steps of treating the plant or animal tissue with at least one photo-active molecular agent, wherein the particular volume of the plant or animal tissue retains at least a portion of the at least one photo-active molecular agent, and then treating the particular volume of the plant or animal tissue with light sufficient to promote a simultaneous two-photon excitation of at least one of the at least one photo-active molecular agent retained in the particular volume of the plant or animal tissue, wherein the at least one photo-active molecular agent becomes active in the particular volume of the plant or animal tissue. There is also disclosed a method for the treatment of cancer in plant or animal tissue and a method for producing at least one photo-activated molecular agent in a particular volume of a material.
    Type: Grant
    Filed: October 30, 1996
    Date of Patent: November 3, 1998
    Assignee: Photogen, Inc.
    Inventors: Walter G. Fisher, Eric A. Wachter, H. Craig Dees