Abstract: The present invention relates to new chemical products which are useful as hypolipemizing and hypocholesterolemizing agents.The new compounds are derivatives of phenoxy isobutyric acid of the general formula ##EQU1## wherein: A is a lower-alkylene bridge of 2 to 6 carbon atoms, either linear or branched,X is a halogen atom,R = h or lower-alkyl,The N of the pyridyl ring can be replaced by an N-oxide, or the compounds can be in the form of their pharmaceutically-acceptable acid addition salts.Pharmaceutical compositions containing these active principles are useful for hypolipemizing and hypocholesterolemizing purposes, e.g., in the prevention and treatment of atherosclerosis and its consequences.
Abstract: The present invention concerns new compositions which are useful as medicaments. These compositions contain vasodilators or vasoregulators and substances which decrease the adhesiveness and aggregability of the blood platelets. They are useful for the prevention and treatment of circulatory insufficiency, whatever the location thereof.
Abstract: 5-Bromo-N-(N.sup.1 -pyrrolidino-alkyl)-ortho-cresotamides having 2 to 5 carbon atoms in the alkyl moiety and therapeutically acceptable salts thereof, compositions containing such compounds useful as antitussives, and a method of suppressing of a cough in a host by administering an effective amount of such a compound with a pharmaceutically acceptable excipient. 5-Bromo-ortho-cresotamide may also be named 5-bromo-2-hydroxy-3-methyl-benzamide.
Type:
Grant
Filed:
January 6, 1975
Date of Patent:
May 18, 1976
Assignee:
Pierre Fabre S.A.
Inventors:
Antoine Stenger, Henri Cousse, Gilbert Mouzin
Abstract: 5-Bromo-ortho-cresotamide and N--C.sub.1 to C.sub.4 --alkyl-5-bromo-ortho-cresotamides are useful for the potentiation of aspirin. 5-Bromo-ortho-cresotamide may also be named 5-Bromo-2-hydroxy-3-methyl-benzamide.
Type:
Grant
Filed:
November 21, 1974
Date of Patent:
March 2, 1976
Assignee:
Pierre Fabre S.A.
Inventors:
M. Antoine Stenger, Henri Cousse, M. Gilbert Mouzin
Abstract: N--C.sub.1 to C.sub.4 -alkyl-5-bromo-ortho-cresotamides; their use as anticonvulsants. 5-Bromo-ortho-cresotamide may also be named 5-Bromo-2-hydroxy-3-methyl-benzamide.
Type:
Grant
Filed:
November 21, 1974
Date of Patent:
February 24, 1976
Assignee:
Pierre Fabre S.A.
Inventors:
M. Antoine Stenger, Henri Cousse, M. Gilbert Mouzin