Patents Assigned to Platypus Technologies, LLC
  • Devices for cell assays
    Patent number: 9968935
    Abstract: The present invention relates to the field of molecular diagnostics. In particular, the present invention provided improved substrates and methods of using liquid crystals and other biophotonically based assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal or other biophotonically based assay formats.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: May 15, 2018
    Assignee: Platypus Technologies, LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel, Josh Sotos, Doug Hansmann, Renee Herber, Joseph Burkholder, Keren Hulkower, Michael Bonds
  • Liquid crystal based analyte detection
    Patent number: 8988620
    Abstract: The present invention relates to the field of detection of viruses, and in particular to detection of viruses using a liquid crystal assay format. In the present invention, virus binding in a detection region is identified by changes in liquid crystal orientation caused by virus binding independent orientation caused by any topography associated with the detection region.
    Type: Grant
    Filed: August 31, 2009
    Date of Patent: March 24, 2015
    Assignee: Platypus Technologies, LLC
    Inventors: Barbara A. Israel, Nicholas Abbott, Christopher Murphy, Karla Hollister, Syrus Soltaninassab, Doug Hansmann, Bharat Raj Acharya
  • Method for assaying cell movement
    Patent number: 8512974
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for analyzing cell invasion.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: August 20, 2013
    Assignee: Platypus Technologies, LLC
    Inventors: Christopher Murphy, Barbara Israel, Nicholas Abbott
  • Method for assaying cell movement
    Patent number: 8268614
    Abstract: The present invention relates to the field of assays of cell movement. In particular, the present invention provides methods for assaying cell movement where inserts are used to confine cells to a defined area in a well of a multiwell plate and movement from the defined area is assayed.
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: September 18, 2012
    Assignee: Platypus Technologies, LLC
    Inventors: Christopher Murphy, Barbara Israel, Nicholas Abbot
  • Detection of vapor phase compounds by changes in physical properties of a liquid crystal
    Patent number: 8178355
    Abstract: The present invention relates to the field of detection of components in gas phase, and in particular to detection of nitric oxide exhaled as a component of breath, using a liquid crystal assay format and a device utilizing liquid crystals as part of a reporting system.
    Type: Grant
    Filed: September 15, 2009
    Date of Patent: May 15, 2012
    Assignee: Platypus Technologies, LLC.
    Inventors: Bharat Acharya, Avijit Sen, Nicholas Abbott, Kurt Kupcho
  • Substrates, devices, and methods for cellular assays
    Patent number: 7842499
    Abstract: The present invention relates to the field of molecular diagnostics. In particular, the present invention provided improved substrates and methods of using liquid crystals and other biophotonically based assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal or other biophotonically based assay formats.
    Type: Grant
    Filed: August 7, 2007
    Date of Patent: November 30, 2010
    Assignee: Platypus Technologies, LLC
    Inventors: Christopher Murphy, Barbara Israel, Nicholas Abbott
  • Substrates, devices, and methods for quantitative liquid crystal assays
    Patent number: 7666661
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assasy format.
    Type: Grant
    Filed: August 26, 2002
    Date of Patent: February 23, 2010
    Assignee: Platypus Technologies, LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel
  • Compositions and liquid crystals
    Patent number: 7662572
    Abstract: The present invention relates to compounds, compositions, and methods in the field of detection of analytes. In particular to detection of viruses, cells, bacteria, lipid-membrane containing organisms, proteins, nucleic acids, carbohydrates and other biomolecules, organic molecules and inorganic molecules using a liquid crystal assay format.
    Type: Grant
    Filed: August 25, 2006
    Date of Patent: February 16, 2010
    Assignee: Platypus Technologies, LLC.
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel
  • Bead based assays using a liquid crystal reporter
    Patent number: 7531366
    Abstract: The present invention relates to the field of detection of analytes, and in particular to detection of viruses, cells, bacteria, lipid-membrane containing organisms, proteins, nucleic acids, carbohydrates and other biomolecules, organic molecules and inorganic molecules using a liquid crystal assay format.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: May 12, 2009
    Assignee: Platypus Technologies, LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel, Doug Hansmann
  • DEVICES FOR CELL ASSAYS
    Publication number: 20090054262
    Abstract: The present invention relates to the field of molecular diagnostics. In particular, the present invention provided improved substrates and methods of using liquid crystals and other biophotonically based assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal or other biophotonically based assay formats.
    Type: Application
    Filed: August 20, 2008
    Publication date: February 26, 2009
    Applicant: Platypus Technologies, LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel, Josh Sotos, Doug Hansmann, Renee Herber, Joseph Burkholder, Karen Hulkower, Michael Bonds
  • Substrates, devices, and methods for cellular assays
    Publication number: 20080160539
    Abstract: The present invention relates to the field of molecular diagnostics. In particular, the present invention provided improved substrates and methods of using liquid crystals and other biophotonically based assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal or other biophotonically based assay formats.
    Type: Application
    Filed: August 7, 2007
    Publication date: July 3, 2008
    Applicant: Platypus Technologies, LLC
    Inventors: Christopher Murphy, Barbara Israel, Nicholas Abbott
  • Compositions and liquid crystals
    Publication number: 20070099249
    Abstract: The present invention relates to compounds, compositions, and methods in the field of detection of analytes. In particular to detection of viruses, cells, bacteria, lipid-membrane containing organisms, proteins, nucleic acids, carbohydrates and other biomolecules, organic molecules and inorganic molecules using a liquid crystal assay format.
    Type: Application
    Filed: August 25, 2006
    Publication date: May 3, 2007
    Applicant: Platypus Technologies, LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel
  • Liquid crystal based analyte detection
    Publication number: 20070042505
    Abstract: The present invention relates to the field of detection of analytes, and in particular to detection of analytes using a liquid crystal assay format. In the present invention, analytes binding in a detection region is identified by changes in liquid crystal orientation caused by analyte binding independent orientation caused by any topography associated with the detection region.
    Type: Application
    Filed: May 5, 2006
    Publication date: February 22, 2007
    Applicant: Platypus Technologies, LLC
    Inventors: Barbara Israel, Nicholas Abbott, Doug Hansmann
  • Detection of analytes
    Publication number: 20070004046
    Abstract: The present invention relates to the field of detection of analytes, and in particular to detection of organophosphates using a liquid crystal assay format and a variety of analytes in stand-off detection formats utilizing liquid crystals as part of reporting system. The present devices find use in detecting cumulative exposure to organophosphates in the aerosol phase.
    Type: Application
    Filed: July 1, 2005
    Publication date: January 4, 2007
    Applicant: Platypus Technologies, LLC
    Inventor: Nicholas Abbott
  • Bead based assays using a liquid crystal reporter
    Publication number: 20060252031
    Abstract: The present invention relates to the field of detection of analytes, and in particular to detection of viruses, cells, bacteria, lipid-membrane containing organisms, proteins, nucleic acids, carbohydrates and other biomolecules, organic molecules and inorganic molecules using a liquid crystal assay format.
    Type: Application
    Filed: January 9, 2006
    Publication date: November 9, 2006
    Applicant: Platypus Technologies, LLC
    Inventors: Nicholas Abbott, Christopher Murphy, Barbara Israel, Doug Hansmann
  • Substrates, devices, and methods for cellular assays
    Patent number: 7018838
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format.
    Type: Grant
    Filed: May 22, 2003
    Date of Patent: March 28, 2006
    Assignee: Platypus Technologies, LLC
    Inventors: Christopher Murphy, Barbara Israel, Nicholas Abbott
  • SUBSTRATES, DEVICES, AND METHODS FOR CELLULAR ASSAYS
    Publication number: 20050221271
    Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format.
    Type: Application
    Filed: May 22, 2003
    Publication date: October 6, 2005
    Applicant: Platypus Technologies, LLC
    Inventors: Christopher Murphy, Barbara Israel, Nicholas Abbott
  • Liquid crystal based analyte detection
    Publication number: 20050064395
    Abstract: The present invention relates to the field of detection of viruses, and in particular to detection of viruses using a liquid crystal assay format. In the present invention, virus binding in a detection region is identified by changes in liquid crystal orientation caused by virus binding independent orientation caused by any topography associated with the detection region.
    Type: Application
    Filed: July 23, 2004
    Publication date: March 24, 2005
    Applicant: Platypus Technologies, LLC
    Inventors: Barbara Israel, Nicholas Abbott, Christopher Murphy, Karla Hollister, Syrus Soltaninassab, Doug Hansmann, Bharat Acharya