Abstract: The present invention relates to the field of detection of viruses, and in particular to detection of viruses using a liquid crystal assay format. In the present invention, virus binding in a detection region is identified by changes in liquid crystal orientation caused by virus binding independent orientation caused by any topography associated with the detection region.
Type:
Application
Filed:
August 31, 2009
Publication date:
January 14, 2010
Applicant:
PLATYPUS TECHNOLOGIES, LLC
Inventors:
Barbara A. Israel, Nicholas Abbott, Christopher Murphy, Karla Hollister, Syrus Soltaninassab, Doug Hansmann, Bharat Raj Acharya
Abstract: The present invention relates to the field of detection of analytes, and in particular to detection of viruses, cells, bacteria, lipid-membrane containing organisms, proteins, nucleic acids, carbohydrates and other biomolecules, organic molecules and inorganic molecules using a liquid crystal assay format.
Type:
Grant
Filed:
January 9, 2006
Date of Patent:
May 12, 2009
Assignee:
Platypus Technologies, LLC
Inventors:
Nicholas Abbott, Christopher Murphy, Barbara Israel, Doug Hansmann
Abstract: The present invention relates to the field of molecular diagnostics. In particular, the present invention provided improved substrates and methods of using liquid crystals and other biophotonically based assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal or other biophotonically based assay formats.
Type:
Application
Filed:
August 20, 2008
Publication date:
February 26, 2009
Applicant:
Platypus Technologies, LLC
Inventors:
Nicholas Abbott, Christopher Murphy, Barbara Israel, Josh Sotos, Doug Hansmann, Renee Herber, Joseph Burkholder, Karen Hulkower, Michael Bonds
Abstract: The present invention relates to the field of molecular diagnostics. In particular, the present invention provided improved substrates and methods of using liquid crystals and other biophotonically based assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal or other biophotonically based assay formats.
Type:
Application
Filed:
August 7, 2007
Publication date:
July 3, 2008
Applicant:
Platypus Technologies, LLC
Inventors:
Christopher Murphy, Barbara Israel, Nicholas Abbott
Abstract: The present invention relates to compounds, compositions, and methods in the field of detection of analytes. In particular to detection of viruses, cells, bacteria, lipid-membrane containing organisms, proteins, nucleic acids, carbohydrates and other biomolecules, organic molecules and inorganic molecules using a liquid crystal assay format.
Type:
Application
Filed:
August 25, 2006
Publication date:
May 3, 2007
Applicant:
Platypus Technologies, LLC
Inventors:
Nicholas Abbott, Christopher Murphy, Barbara Israel
Abstract: The present invention relates to the field of detection of analytes, and in particular to detection of analytes using a liquid crystal assay format. In the present invention, analytes binding in a detection region is identified by changes in liquid crystal orientation caused by analyte binding independent orientation caused by any topography associated with the detection region.
Type:
Application
Filed:
May 5, 2006
Publication date:
February 22, 2007
Applicant:
Platypus Technologies, LLC
Inventors:
Barbara Israel, Nicholas Abbott, Doug Hansmann
Abstract: The present invention relates to the field of detection of analytes, and in particular to detection of organophosphates using a liquid crystal assay format and a variety of analytes in stand-off detection formats utilizing liquid crystals as part of reporting system. The present devices find use in detecting cumulative exposure to organophosphates in the aerosol phase.
Abstract: The present invention relates to the field of detection of analytes, and in particular to detection of viruses, cells, bacteria, lipid-membrane containing organisms, proteins, nucleic acids, carbohydrates and other biomolecules, organic molecules and inorganic molecules using a liquid crystal assay format.
Type:
Application
Filed:
January 9, 2006
Publication date:
November 9, 2006
Applicant:
Platypus Technologies, LLC
Inventors:
Nicholas Abbott, Christopher Murphy, Barbara Israel, Doug Hansmann
Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format.
Type:
Grant
Filed:
May 22, 2003
Date of Patent:
March 28, 2006
Assignee:
Platypus Technologies, LLC
Inventors:
Christopher Murphy, Barbara Israel, Nicholas Abbott
Abstract: The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format.
Type:
Application
Filed:
May 22, 2003
Publication date:
October 6, 2005
Applicant:
Platypus Technologies, LLC
Inventors:
Christopher Murphy, Barbara Israel, Nicholas Abbott
Abstract: The present invention relates to the field of detection of viruses, and in particular to detection of viruses using a liquid crystal assay format. In the present invention, virus binding in a detection region is identified by changes in liquid crystal orientation caused by virus binding independent orientation caused by any topography associated with the detection region.
Type:
Application
Filed:
July 23, 2004
Publication date:
March 24, 2005
Applicant:
Platypus Technologies, LLC
Inventors:
Barbara Israel, Nicholas Abbott, Christopher Murphy, Karla Hollister, Syrus Soltaninassab, Doug Hansmann, Bharat Acharya