Patents Assigned to Poli Industria Chimica
  • Processes for the preparation of pharmaceutical compositions containing bromocriptine having high stability and related products
    Patent number: 5066495
    Abstract: Processes for the preparation of bromocriptine tablets or capsules wherein the active ingredient is protected by inclusion in an excipient or by separated granulation of the excipients and mixing granulate with a mixture of the active ingredient and a excipient having low moisture content.
    Type: Grant
    Filed: March 30, 1990
    Date of Patent: November 19, 1991
    Assignee: Poli Industria Chimica S. p. A.
    Inventors: Luigi Moro, Achille Fiori, Alberto Natali
  • Derivatives of thiazolidine-4-carboxylic acid, its preparation and pharmaceutical compositions containing it
    Patent number: 5066644
    Abstract: Ester or amide derivatives of 3-pyroglutamylthiazolidine-4-carboxylic acid exhibit interesting immunostimulating, antitoxic, antiinflammatory, antioxidental, antiageing properties.
    Type: Grant
    Filed: February 9, 1990
    Date of Patent: November 19, 1991
    Assignee: Poli Industria Chimica S.p.A.
    Inventors: Stefano Poli, Germano Coppi, Lucio Del Corona
  • N-cycloalkylaminoethylbenzamide derivatives, their synthesis and pharmaceutical preparations
    Patent number: 5010108
    Abstract: New N-(2-cycloalkylamino)ethyl-substituted benzamides having a powerful stimulating activity on gastric motility and with a low central anti-dopaminergic activity are described. The synthesis and the pharmaceutical preparation for therapeutical use are also described.
    Type: Grant
    Filed: March 15, 1989
    Date of Patent: April 23, 1991
    Assignee: Poli Industria Chimica S.p.A.
    Inventors: Stefano Poli, Germano Coppi, Lucio Del Corona
  • Derivative of thiazolidine-4-carboxylic acid, its preparation and pharmaceutical compositions containing it
    Patent number: 4839387
    Abstract: 3-L-pyroglutamoyl-thiazolidine-4-carboxylic acid, prepared starting from an activated ester of L-pyroglutamic acid from pyroglutamoyl chloride and L-thiazolidine-4-carboxylic acid, exhibits interesting immunostimulant, antitoxic, antiinflammatory, antioxidant and anti-aging properties.
    Type: Grant
    Filed: January 15, 1988
    Date of Patent: June 13, 1989
    Assignee: Poli Industria Chimica S.P.A.
    Inventor: Stefano Poli
  • Tetrahydroisoquinoline ethyl esters of 1,4-dihydropyridines and antihypertensive compositions
    Patent number: 4769374
    Abstract: 1,4-Dihydropiridine derivatives having the formula ##STR1## wherein R is methyl, ethyl or isopropyl, are endowed with a hypotensive, vasodilator and Ca.sup.++ -antagonistic activity.
    Type: Grant
    Filed: September 23, 1985
    Date of Patent: September 6, 1988
    Assignee: Poli Industria Chimica S.p.A.
    Inventor: Giangiacomo Massaroli
  • Pharmaceutical methods having dopaminergic activity
    Patent number: 4673681
    Abstract: A pharmaceutical composition containing .alpha.-dihydroergocryptine, or a salt thereof, is used in combination with pharmaceutically acceptable carrier means or excipient for the treatment of Parkinson's disease, depression or cephalalgias is disclosed. A method for administering the composition to a patient is also provided.
    Type: Grant
    Filed: April 2, 1986
    Date of Patent: June 16, 1987
    Assignee: Poli Industria Chimica S.p.A.
    Inventor: Stefano Poli
  • Imidazo[1,2-a]pyridines having anti-ulcer activity
    Patent number: 4311702
    Abstract: Imidazo[1,2-a]pyridine of the formula ##STR1## in which R represents H or CH.sub.3 and R.sub.1 represents H or CH.sub.3 which can be used in human therapy as inhibitors of gastric secretion. The compounds are prepared by reacting a methylisothiourea of the formula ##STR2## with methylamine in aqueous solution of dimethyl formamide or in hydroalcoholic solution, at temperatures between 0.degree. and 50.degree. C.
    Type: Grant
    Filed: October 30, 1980
    Date of Patent: January 19, 1982
    Assignee: Poli Industria Chimica S.p.A.
    Inventor: Giangiacomo Massaroli
  • 4-Carbethoxy-carbonilamino-pyrimidines and a process for their preparation
    Patent number: 4254126
    Abstract: New compounds, carbethoxy-carbonilamino pyrimidines are prepared from 4-amino pyrimidines and find application in pharmaceutical compositions for the treatment of allergic reactions and peptic ulcer.
    Type: Grant
    Filed: October 22, 1979
    Date of Patent: March 3, 1981
    Assignee: POLI Industria Chimica S.p.A.
    Inventor: Giangiacomo Massaroli
  • 4-Pyrimidyl sulfides for the treatment of gastric ulcers
    Patent number: 4224327
    Abstract: The invention concerns 4-pyrimidyl sulfides of the general formula ##STR1## wherein R.sub.1 and R.sub.2 are the same or different, and are H, NH.sub.2 or CH.sub.3. The compounds and pharmaceutical compositions containing the compounds, useful for the treatment of gastric ulcers and pathological states relating to gastric hypersecretion, exhibit a low toxicity and high degree of effectiveness.
    Type: Grant
    Filed: January 25, 1979
    Date of Patent: September 23, 1980
    Assignee: Poli Industria Chimica S.p.A.
    Inventor: Giangiacomo Massaroli
  • (Pyridyl-3)-methyl 2-(p-chlorophenoxy-phenoxy) propionate and use as a hypolipemising drug
    Patent number: 3992543
    Abstract: (Pyridyl-3)-methyl 2-(p-chlorophenoxy-phenoxy) propionate has interesting properties in reducing cholesterolemia, lipidemia and triglyceridemia, in doses 10 times lower than ethyl p-chlorophenoxy-isobutyrate.
    Type: Grant
    Filed: November 11, 1975
    Date of Patent: November 16, 1976
    Assignee: Poli Industria Chimica S.p.A.
    Inventor: Giangiacomo Massaroli