Abstract: An stable electrohydrodynamic filament is obtained by causing a straight electrohydrodynamic filament formed from a liquid to emerge from a Taylor cone, the filament having a diameter of from 10 nm to 100 ?m. Such filaments are useful in electrohydrodynamic printing and manufacturing techniques and their application in liquid drop/particle and fiber production, colloidal deployment and assembly, and composite materials processing.
Type:
Grant
Filed:
October 31, 2006
Date of Patent:
December 9, 2014
Assignee:
The Trustees of Princeton University
Inventors:
Ilhan A. Aksay, Hak Fei Poon, Sibel Korkut, Chuan-hua Chen, Joy Wagner Saville
Abstract: The present invention relates to methods and devices for separating particles according to size. More specifically, the present invention relates to a microfluidic method and device for the separation of particles according to size using an array comprising a network of gaps, wherein the field flux from each gap divides unequally into subsequent gaps. In one embodiment, the array comprises an ordered array of obstacles in a microfluidic channel, in which the obstacle array is asymmetric with respect to the direction of an applied field.
Type:
Grant
Filed:
October 8, 2012
Date of Patent:
December 9, 2014
Assignee:
The Trustees of Princeton University
Inventors:
Lotien Richard Huang, James Christopher Sturm, Robert Hamilton Austin
Abstract: A machine-learning accelerator (MLA) integrated circuit for extracting features from signals and performing inference computations is disclosed. The MLA integrated circuit includes a framework of finite state machine (FSM) kernels that are machine-learning algorithms implemented in hardware. The MLA integrated circuit further includes a kernel controller having mathematical structures implemented in hardware in communication with the framework of FSM kernels. An arithmetic engine implemented in hardware within the MLA integrated circuit is in communication with the kernel controller to perform computations for the mathematical structures. In at least one embodiment, the MLA integrated circuit includes a compression decompression accelerator (CDA) implemented in hardware and coupled between a memory and the kernel controller for compressing data to be stored in the memory and for decompressing data retrieved from the memory.
Abstract: A conductive circuit containing a polymer composite, which contains at least one polymer and a modified graphite oxide material, containing thermally exfoliated graphite oxide having a surface area of from about 300 m2/g to 2600 m2/g, and a method of making the same.
Abstract: A relatively high-resolution image from a conventional camera can be computationally combined with a relatively low-resolution wavefront measurement from, for example, a Shack-Hartmann sensor in order to construct a relatively high-resolution light-field image.
Type:
Application
Filed:
May 9, 2014
Publication date:
November 13, 2014
Applicant:
Trustees of Princeton University
Inventors:
Jason W. Fleischer, Chien-Hung Lu, Stefan Muenzel
Abstract: A chip multiprocessor includes a plurality of cores each having a translation lookaside buffer (TLB) and a prefetch buffer (PB). Each core is configured to determine a TLB miss on the core's TLB for a virtual page address and determine whether or not there is a PB hit on a PB entry in the PB for the virtual page address. If it is determined that there is a PB hit, the PB entry is added to the TLB. If it is determined that there is not a PB hit, the virtual page address is used to perform a page walk to determine a translation entry, the translation entry is added to the TLB and the translation entry is prefetched to each other one of the plurality of cores.
Type:
Grant
Filed:
March 12, 2010
Date of Patent:
November 4, 2014
Assignee:
Trustees of Princeton University
Inventors:
Abhishek Bhattacharjee, Margaret Martonosi
Abstract: A method and apparatus for performing nanoimprint lithography. When an electric field is applied between the mold and the substrate, various forces can be generated among molds, substrates, and resists. The electrostatic force between the mold and the substrate can serve as an imprinting pressure to press the structured mold into the conformable resist. In addition, the electric field induces additional wetting forces (electrowetting or dielectrophoresis) in a liquid resist, which can assist the flow and filling of the liquid resist into fine structures.
Abstract: Thin-film transistors are made using an organosilicate glass (OSG) as an insulator material. The organosilicate glasses may be SiO2-silicone hybrid materials deposited by plasma-enhanced chemical vapor deposition from siloxanes and oxygen. These hybrid materials may be employed as the gate dielectric, as a subbing layer, and/or as a back channel passivating layer. The transistors may be made in any conventional TFT geometry.
Type:
Grant
Filed:
July 30, 2009
Date of Patent:
September 16, 2014
Assignee:
The Trustees of Princeton University
Inventors:
Lin Han, Prashant Mandlik, Sigurd Wagner
Abstract: An irregular connectivity mesh representative of a surface having an arbitrary topology is processed using a non-uniform relaxation procedure. The non-uniform relaxation procedure minimizes differences between vectors normal to faces of pairs of triangles having a common edge and located within a designated neighborhood of a given vertex. The relaxation procedure may be used to construct subdivision and pyramid algorithms for performing processing operations such as upsampling, downsampling and filtering on irregular connectivity meshes. The signal processing algorithms may be utilized in applications such as smoothing, enhancement, editing, texture mapping and compression.
Type:
Grant
Filed:
September 13, 1999
Date of Patent:
September 9, 2014
Assignees:
Alcatel Lucent, California Institute of Technology, Trustees of Princeton University
Inventors:
Igor V. Guskov, Peter Schröder, Wim Sweldens
Abstract: Immunogenic compositions and prophylactic or therapeutic vaccines for use in protecting and treating against human cytomegalovirus (CMV) are disclosed. Subunit vaccines comprising a human CMV protein complex comprising pUL128 or pUL130, and nucleic acid vaccines comprising at least one nucleic acid encoding a CMV protein complex comprising pUL128 or pUL130 are described. Also disclosed are therapeutic antibodies reactive against a CMV protein complex comprising pUL128 or pUL130, as well as methods for screening compounds that inhibit CMV infection of epithelial and endothelial cells, methods for immunizing a subject against CMV infection, methods for determining the capability of neutralizing antibodies to inhibit CMV infection of cell types other than fibroblasts, and methods of diminishing an CMV infection.
Abstract: Methods of halogenating a carbon containing compound having an sp3 C—H bond are provided. Methods of fluorinating a carbon containing compound comprising halogenation with Cl or Br followed by nucleophilic substitution with F are provided. Methods of direct oxidative C—H fluorination of a carbon containing compound having an sp3 C—H bond are provided. The halogenated products of the methods are provided.
Abstract: Organic electronic devices comprising “remotely” doped materials comprising a combination of at least three layers. Such devices can include “remotely p-doped” structures comprising: a channel layer comprising at least one organic semiconductor channel material; a dopant layer, which comprises at least one p-dopant material and optionally at least one organic hole transport material; and a spacer layer disposed between and in electrical contact with both the channel layer and the dopant layer, comprising an organic semiconducting spacer material; or alternatively can include “remotely n-doped” structures comprising a combination of at least three layers: a channel layer comprising at least one organic semiconductor channel material; a dopant layer which comprises at least one organic electron transport material doped with an n-dopant material; and a spacer layer disposed between and in electrical contact with the channel layer and the dopant layer, comprising an organic semiconducting spacer material.
Type:
Application
Filed:
November 27, 2013
Publication date:
August 21, 2014
Applicants:
The Trustees of Princeton University, Georgia Tech Research Corporation
Inventors:
Wei ZHAO, Yabing QI, Antoine KAHN, Seth R. MARDER, Stephen BARLOW
Abstract: The present invention provides compositions and methods for programming mammalian cells to perform desired functions. In particular, the present invention provides compositions and methods for programming stem cells to differentiate into a desired cell type. A quorum sensing systems that regulates the expression of cell fate regulators is introduced into mammalian host cells, such as stem cells. The quorum sensing systems generally comprises vectors that express the components of a bacterial quorum sensing pathway, including proteins which catalyze the synthesis of an autoinducer and a gene encoding a regulatory partner of the autoinducer, and vectors in which genes encoding cell fate regulators are operably linked to a promoter induced by the autoinducer/regulatory partner complex.
Type:
Application
Filed:
February 6, 2014
Publication date:
August 21, 2014
Applicant:
The Trustees of Princeton University
Inventors:
Ron Weiss, Ihor Lemischka, Priscilla Purnick
Abstract: Systems and methods for remote and/or portable detection are provided. The system can include a source of coherent laser pulses, components for converting the coherent laser pulses into first beam pulses at a first wavelength value, second beam pulses at a second wavelength value, and third beam pulses at a third wavelength value. Systems can further include optical components configured to delay at least one of the first beam pulses, the second beam pulses, and the third beam pulses in order to create delayed beam pulses, and a focusing component configured direct a substantially collinear combination of the delayed beam pulses and two of a set of: the first beam pulses, the second beam pulses, and the third beam pulses, onto a sample.
Abstract: Methods of halogenating a carbon containing compound having an sp3 C—H bond are provided. Methods of fluorinating a carbon containing compound comprising halogenation with Cl or Br followed by nucleophilic substitution with F are provided. Methods of direct oxidative C—H fluorination of a carbon containing compound having an sp3 C—H bond are provided. The halogenated products of the methods are provided.
Abstract: The disclosure relates to obstacle array devices (also known as bump array devices) for separating populations of particles by size. Improvements over previous obstacle array devices are realized by causing the fluid velocity profile across gaps between obstacles to be asymmetrical with respect to the plane that bisects the gap and is parallel to the direction of bulk fluid flow. Such asymmetry can be achieved by selecting the shape(s) of the obstacles bounding the gap such that the portions of the obstacles upstream from, downstream from or bridging the narrowest portion of the gap are asymmetrical with respect to that plane. Improvements are also realized by using obstacles that have sharp edges bounding the gaps. Other improvements are realized by selecting obstacle shapes such that the critical particle dimensions defined by the gaps in two different fluid flow directions differ.
Type:
Grant
Filed:
December 7, 2012
Date of Patent:
July 22, 2014
Assignee:
The Trustees of Princeton University
Inventors:
Kevin Loutherback, James C. Sturm, Robert Austin, Keith Morton, Jason Puchalla
Abstract: A novel small molecule antagonizes two types of acyl homoserine lactone receptors: membrane-bound and cytoplasmic. A focused library of analogs and derivatives of the original antagonist was synthesized. Analog and derivative molecules harbor a range of activities. The novel small molecule and most potent antagonist protects the eukaryote Caenorhabditis elegans from quorum-sensing-mediated killing by the bacterial pathogen Chromobacterium violaceum. The saving of C. elegans demonstrates the use of these molecules as small molecule antimicrobials.
Type:
Grant
Filed:
July 17, 2012
Date of Patent:
July 8, 2014
Assignee:
The Trustees of Princeton University
Inventors:
Bonnie L. Bassler, Lee R. Swem, Scott M. Ulrich, Colleen T. O'Loughlin
Abstract: Printed electronic device comprising a substrate onto at least one surface of which has been applied a layer of an electrically conductive ink comprising functionalized graphene sheets and at least one binder. A method of preparing printed electronic devices is further disclosed.
Type:
Application
Filed:
February 25, 2014
Publication date:
June 26, 2014
Applicants:
Vorbeck Materials Corporation, The Trustees of Princeton University
Inventors:
John M. CRAIN, John S. Lettow, IIhan A. Aksay, Sibel Korkut, Katherine S. Chiang, Chuan-Hua Chen, Robert K. Prud'Homme
Abstract: The present invention provides a dense-coverage, adherent phosphorous-based coating on the native oxide surface of a material. Disclosed phosphorous-based coatings include phosphate and organo-phosphonate coatings. The present invention also provides further derivatization of the phosphorous-based coatings to yield dense surface coverage of chemically reactive coatings and osetoblast adhesion-promoting and proliferation-promoting coatings on the native oxide surface of a titanium material.
Type:
Grant
Filed:
September 21, 2011
Date of Patent:
June 24, 2014
Assignee:
The Trustees of Princeton University
Inventors:
Jeffrey Schwartz, Michael J. Avaltroni, Kim S. Midwood, Jean E. Schwarzbauer, Ellen Gawalt
Abstract: An optical integration circuit includes a semiconductor optical amplifier (SOA), a readout mechanism coupled to the SOA, and an optical filter coupled to an output of the SOA. The SOA has a decaying response function and an input for receiving an optical input signal having a first wavelength. The SOA is configured to output an optical signal representing a temporal integration of the optical input signal. The readout mechanism provides an optical readout signal having a second wavelength to the SOA for measuring a state of the SOA. The optical filter is configured to receive the signal representing the temporal integration of the optical input signal and block optical signals having the first wavelength.
Type:
Grant
Filed:
March 10, 2010
Date of Patent:
June 10, 2014
Assignees:
Lockheed Martin Corporation, The Trustees of Princeton University
Inventors:
David Rosenbluth, Paul R. Prucnal, Konstantin Kravtsov