Patents Assigned to Princeton University
  • Patent number: 8254242
    Abstract: A system and method for initial ranging in wireless communication systems is provided. A plurality of orthogonal frequency division multiplexing (OFDM) blocks are received by an OFDMA base station transceiver from a plurality of remote user devices in wireless communication with the base station. A ranging subchannel is extracted from the OFDM blocks. The number of active codes in the ranging subchannel is determined, active codes are identified, and carrier frequency offsets (CFOs) are estimated for each active code. Timing delays and power levels for each active code are then estimated. The estimated CFOs, timing delays, and power levels are broadcasted by the base station to the remote user devices, so that the user devices can utilize same to adjust transmission parameters to optimize power levels and synchronize communication with the base station.
    Type: Grant
    Filed: May 2, 2008
    Date of Patent: August 28, 2012
    Assignee: Princeton University
    Inventors: Michele Morelli, H. Vincent Poor, Luca Sanguinetti
  • Patent number: 8247443
    Abstract: A novel small molecule antagonizes two types of acyl homoserine lactone receptors: membrane-bound and cytoplasmic. A focused library of analogs and derivatives of the original antagonist was synthesized. Analog and derivative molecules harbor a range of activities. The novel small molecule and most potent antagonist protects the eukaryote Caenorhabditis elegans from quorum-sensing-mediated killing by the bacterial pathogen Chromobacterium violaceum. The saving of C. elegans demonstrates the use of these molecules as small molecule antimicrobials.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: August 21, 2012
    Assignee: The Trustees of Princeton University
    Inventors: Bonnie L. Bassler, Lee R. Swem, Scott M. Ulrich, Colleen T. O'Loughlin
  • Patent number: 8248681
    Abstract: The present disclosure relates generally to polyaniline (PANI) materials capable of undergoing stable and reversible polyelectrochromic transitions between multiple oxidation states. More specifically, the embodiments described herein include novel PANI-PAAMPSA structures that are capable of undergoing stable and reversible transitions between the ES, LB and PB oxidation states. In some embodiments, the structures described are capable of undergoing stable transitions over a broad pH range. Also described herein are methods of preparing certain electrochromic structures.
    Type: Grant
    Filed: January 4, 2011
    Date of Patent: August 21, 2012
    Assignee: The Trustees of Princeton University
    Inventors: Yueh-Lin Loo, Joung Eun Yoo, Jacob Tarver
  • Patent number: 8243362
    Abstract: This invention relates generally to the field of quasicrystalline structures. In preferred embodiments, the structure is heterostructure comprising dielectric materials arranged in two-dimensional space such that the overall structure is more rotationally symmetric than periodic structures. Symmetry may be five-fold or greater than six-fold. Such higher rotational symmetries provide stopgaps in nearly all directions. More particularly, the invention relates to the use of quasicrystalline structures for optical, mechanical, electrical and magnetic purposes. In some embodiments, the invention relates to manipulating, controlling, modulating and directing waves including electromagnetic, sound, spin, and surface waves, for a pre-selected range of wavelengths propagating in multiple directions.
    Type: Grant
    Filed: October 12, 2011
    Date of Patent: August 14, 2012
    Assignee: The Trustees Of Princeton University
    Inventors: Paul Joseph Steinhardt, Paul Michael Chaikin, Weining Man
  • Patent number: 8242493
    Abstract: An organic photosensitive optoelectronic device includes an anode, a cathode, and a donor-acceptor heterojunction between the anode and the cathode, the heterojunction including a donor-like material and an acceptor-like material, wherein at least one of the donor-like material and the acceptor-like material includes a subphthalocyanine, a subporphyrin, and/or a subporphyrazine compound, wherein the subporphyrin or subporphyrazine compound includes boron.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: August 14, 2012
    Assignees: The Trustees of Princeton University, The Regents of the University of Michigan, The University of Southern California
    Inventors: Barry Rand, Stephen R. Forrest, Kristin L. Mutolo, Elizabeth Mayo, Mark E. Thompson
  • Patent number: 8232267
    Abstract: This invention provides a novel class of substituted macrocyclic porphyrin compounds. The compounds are useful as peroxynitrite decomposition catalysts. Pharmaceutical compositions, and methods of making and using the compounds, or a pharmaceutically acceptable salt, hydrate, or prodrug thereof are also described.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: July 31, 2012
    Assignee: The Trustees of Princeton University
    Inventor: John T. Groves
  • Patent number: 8221804
    Abstract: The invention encompasses novel compositions containing a methylation modifying compound isolated from botanical raw materials, including a fruit of the genus Coffea, and microbial raw materials, methods of making such compositions, and methods of treating or preventing human disease using such compositions. The methylation modifying compound in botanical extracts of the present invention can dramatically increase the level of methylation of PP2A, thus increasing cognitive function, particularly in persons suffering from or prone to developing Alzheimer's disease.
    Type: Grant
    Filed: February 3, 2006
    Date of Patent: July 17, 2012
    Assignees: Signum Biosciences, Inc., Trustees of Princeton University
    Inventors: Jeffry B. Stock, Maxwell Stock, Haoming Gu, Gregory B Stock, Zhu Li, Peter Michael Wolanin
  • Patent number: 8222072
    Abstract: Methods of transferring a metal and/or organic layer from a patterned stamp, preferably a soft, elastomeric stamp, to a substrate are provided. The patterned metal or organic layer may be used for example, in a wide range of electronic devices. The present methods are particularly suitable for nanoscale patterning of organic electronic components.
    Type: Grant
    Filed: March 13, 2003
    Date of Patent: July 17, 2012
    Assignee: The Trustees of Princeton University
    Inventors: Changsoon Kim, Stephen R. Forrest
  • Publication number: 20120145234
    Abstract: Electrodes for dye-sensitized solar cells comprising graphene sheets and at least one binder. The electrodes may be conductive and catalytic counter electrodes. The electrodes may be flexible.
    Type: Application
    Filed: October 10, 2011
    Publication date: June 14, 2012
    Applicant: The Trustees of Princeton University
    Inventors: Joseph D. ROY-MAYHEW, Ilhan A. Aksay
  • Patent number: 8194307
    Abstract: A tunable acoustic gradient index of refraction (TAG) lens and system are provided that permit, in one aspect, dynamic selection of the lens output, including dynamic focusing and imaging. The system may include a TAG lens and at least one of a source and a detector of electromagnetic radiation. A controller may be provided in electrical communication with the lens and at least one of the source and detector and may be configured to provide a driving signal to control the index of refraction and to provide a synchronizing signal to time at least one of the source and the detector relative to the driving signal. Thus, the controller is able to specify that the source irradiates the lens (or detector detects the lens output) when a desired refractive index distribution is present within the lens, e.g. when a desired lens output is present.
    Type: Grant
    Filed: February 25, 2008
    Date of Patent: June 5, 2012
    Assignee: Trustees of Princeton University
    Inventors: Craig B. Arnold, Euan McLeod, Alexandre Mermillod-Blondin
  • Patent number: 8192870
    Abstract: A supercapacitor or battery electrode containing a modified graphite oxide material, which is a thermally exfoliated graphite oxide with a surface area of from about 300 m2/g to 2600 m2/g.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: June 5, 2012
    Assignee: The Trustees of Princeton University
    Inventors: Ilhan A. Aksay, Ted Chao-Hung Yeh, Dudley A. Saville, Joy Saville, legal representative
  • Patent number: 8173362
    Abstract: Immunogenic compositions and prophylactic or therapeutic vaccines for use in protecting and treating against human cytomegalovirus (CMV) are disclosed. Subunit vaccines comprising a human CMV protein complex comprising pUL128 or pUL130, and nucleic acid vaccines comprising at least one nucleic acid encoding a CMV protein complex comprising pUL128 or pUL130 are described. Also disclosed are therapeutic antibodies reactive against a CMV protein complex comprising pUL128 or pUL130, as well as methods for screening compounds that inhibit CMV infection of epithelial and endothelial cells, methods for immunizing a subject against CMV infection, methods for determining the capability of neutralizing antibodies to inhibit CMV infection of cell types other than fibroblasts, and methods of diminishing an CMV infection.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: May 8, 2012
    Assignee: The Trustees of Princeton University
    Inventors: Thomas Shenk, Dai Wang
  • Patent number: 8158677
    Abstract: Alterations of certain metabolite concentrations and fluxes that occur in response to viral infection are described. Host cell enzymes in the involved metabolic pathways are selected as targets for intervention; i.e., to restore metabolic flux to disadvantage viral replication, or to further derange metabolic flux resulting in “suicide” of viral-infected cells (but not uninfected cells) in order to limit viral propagation. While any of the enzymes in the relevant metabolic pathway can be selected, pivotal enzymes at key control points in these metabolic pathways are preferred as candidate antiviral drug targets. Inhibitors of these enzymes are used to reverse, or redirect, the effects of the viral infection. Drug candidates are tested for antiviral activity using screening assays in vitro and host cells, as well as in animal models. Animal models are then used to test efficacy of candidate compounds in preventing and treating viral infections. The antiviral activity of enzyme inhibitors is demonstrated.
    Type: Grant
    Filed: June 2, 2008
    Date of Patent: April 17, 2012
    Assignee: The Trustees of Princeton University
    Inventors: Josh Munger, Bryson Bennett, Thomas Shenk, Joshua Rabinowitz
  • Publication number: 20120088084
    Abstract: A conductive circuit containing a polymer composite, which contains at least one polymer and a modified graphite oxide material, containing thermally exfoliated graphite oxide having a surface area of from about 300 m2/g to 2600 m2/g, and a method of making the same.
    Type: Application
    Filed: March 31, 2011
    Publication date: April 12, 2012
    Applicant: The Trustees of Princeton University
    Inventors: Robert K. PRUD'HOMME, Ilhan A. Aksay
  • Patent number: 8137699
    Abstract: This invention discloses a process for making nanopanticles of amphiphilic copolymers by flash precipitation. Nanoparticles may be of amphiphilic copolymer alone or may contain an additive target molecule, preferably an organic active. The inclusion of additive target molecules in amphiphilic copolymer nanoparticles can alter their water solubility characteristics, fluid dynamics, and/or stability. Changing an additive target molecule's solubility and stability in an nanoparticle can make a water insoluble compound suitable for pharmaceutical administration as well as specifically target the molecule to a specific area of a patient's body. The process affords the production of nanoparticles at high absolute active content, at high yield, high productivity, and high processing rates while using unusually low amounts of amphiphilic copolymers. Furthermore, the resulting particles exhibit sufficient stability for post processing as desired.
    Type: Grant
    Filed: March 29, 2002
    Date of Patent: March 20, 2012
    Assignee: Trustees of Princeton University
    Inventors: Brian K Johnson, Robert K Prud'homme
  • Patent number: 8117436
    Abstract: A hybrid nanotube, high-performance, dynamically reconfigurable architecture, NATURE, is provided, and a design optimization flow method and system, NanoMap. A run-time reconfigurable architecture is provided by associating a non-volatile universal memory to each logic element to enable cycle-by-cycle reconfiguration and logic folding, while remaining CMOS compatible. Through logic folding, significant logic density improvement and flexibility in performing area-delay tradeoffs are possible. NanoMap incorporates temporal logic folding during the logic mapping, temporal clustering and placement steps. NanoMap provides for automatic selection of a best folding level, and uses force-direct scheduling to balance resources across folding stages. Mapping can thereby target various optimization objectives and user constraints.
    Type: Grant
    Filed: April 19, 2007
    Date of Patent: February 14, 2012
    Assignees: Queen's University at Kingston, Trustees of Princeton University
    Inventors: Wei Zhang, Niraj K. Jha, Li Shang
  • Patent number: 8110026
    Abstract: A gas diffusion barrier contains a polymer matrix and a functional graphene which displays no signature of graphite and/or graphite oxide, as determined by X-ray diffraction.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: February 7, 2012
    Assignee: The Trustees of Princeton University
    Inventors: Robert Prud'Homme, Christopher O'Neil, Bulent Ozbas, Ilhan Aksay, Richard Register, Douglas Adamson
  • Patent number: 8110524
    Abstract: A gas storage cylinder or gas storage cylinder liner, formed from a polymer composite, containing at least one polymer and a modified graphite oxide material, which is a thermally exfoliated graphite oxide with a surface area of from about 300 m2/g to 2600 m2/g.
    Type: Grant
    Filed: August 19, 2008
    Date of Patent: February 7, 2012
    Assignee: The Trustees of Princeton University
    Inventors: Robert K. Prud'Homme, Ilhan A. Aksay
  • Patent number: 8105976
    Abstract: A separation medium, such as a chromatography filling or packing, containing a modified graphite oxide material, which is a thermally exfoliated graphite oxide with a surface area of from about 300 m2/g to 2600 m2/g, wherein the thermally exfoliated graphite oxide has a surface that has been at least partially functionalized.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: January 31, 2012
    Assignee: The Trustees of Princeton University
    Inventors: Robert K. Prud'homme, Ilhan A. Aksay, Margarita Herrera-Alonso
  • Publication number: 20120006728
    Abstract: The present invention relates to methods and devices for separating particles according to size. More specifically, the present invention relates to a microfluidic method and device for the separation of particles according to size using an array comprising a network of gaps, wherein the field flux from each gap divides unequally into subsequent gaps. In one embodiment, the array comprises an ordered array of obstacles in a microfluidic channel, in which the obstacle array is asymmetric with respect to the direction of an applied field.
    Type: Application
    Filed: July 12, 2011
    Publication date: January 12, 2012
    Applicant: The Trustees of Princeton University
    Inventors: Lotien Richard Huang, James Christopher Sturm, Robert Hamilton Austin