Abstract: A system and method for initial ranging in wireless communication systems is provided. A plurality of orthogonal frequency division multiplexing (OFDM) blocks are received by an OFDMA base station transceiver from a plurality of remote user devices in wireless communication with the base station. A ranging subchannel is extracted from the OFDM blocks. The number of active codes in the ranging subchannel is determined, active codes are identified, and carrier frequency offsets (CFOs) are estimated for each active code. Timing delays and power levels for each active code are then estimated. The estimated CFOs, timing delays, and power levels are broadcasted by the base station to the remote user devices, so that the user devices can utilize same to adjust transmission parameters to optimize power levels and synchronize communication with the base station.
Type:
Grant
Filed:
May 2, 2008
Date of Patent:
August 28, 2012
Assignee:
Princeton University
Inventors:
Michele Morelli, H. Vincent Poor, Luca Sanguinetti
Abstract: A novel small molecule antagonizes two types of acyl homoserine lactone receptors: membrane-bound and cytoplasmic. A focused library of analogs and derivatives of the original antagonist was synthesized. Analog and derivative molecules harbor a range of activities. The novel small molecule and most potent antagonist protects the eukaryote Caenorhabditis elegans from quorum-sensing-mediated killing by the bacterial pathogen Chromobacterium violaceum. The saving of C. elegans demonstrates the use of these molecules as small molecule antimicrobials.
Type:
Grant
Filed:
December 21, 2009
Date of Patent:
August 21, 2012
Assignee:
The Trustees of Princeton University
Inventors:
Bonnie L. Bassler, Lee R. Swem, Scott M. Ulrich, Colleen T. O'Loughlin
Abstract: The present disclosure relates generally to polyaniline (PANI) materials capable of undergoing stable and reversible polyelectrochromic transitions between multiple oxidation states. More specifically, the embodiments described herein include novel PANI-PAAMPSA structures that are capable of undergoing stable and reversible transitions between the ES, LB and PB oxidation states. In some embodiments, the structures described are capable of undergoing stable transitions over a broad pH range. Also described herein are methods of preparing certain electrochromic structures.
Type:
Grant
Filed:
January 4, 2011
Date of Patent:
August 21, 2012
Assignee:
The Trustees of Princeton University
Inventors:
Yueh-Lin Loo, Joung Eun Yoo, Jacob Tarver
Abstract: This invention relates generally to the field of quasicrystalline structures. In preferred embodiments, the structure is heterostructure comprising dielectric materials arranged in two-dimensional space such that the overall structure is more rotationally symmetric than periodic structures. Symmetry may be five-fold or greater than six-fold. Such higher rotational symmetries provide stopgaps in nearly all directions. More particularly, the invention relates to the use of quasicrystalline structures for optical, mechanical, electrical and magnetic purposes. In some embodiments, the invention relates to manipulating, controlling, modulating and directing waves including electromagnetic, sound, spin, and surface waves, for a pre-selected range of wavelengths propagating in multiple directions.
Type:
Grant
Filed:
October 12, 2011
Date of Patent:
August 14, 2012
Assignee:
The Trustees Of Princeton University
Inventors:
Paul Joseph Steinhardt, Paul Michael Chaikin, Weining Man
Abstract: An organic photosensitive optoelectronic device includes an anode, a cathode, and a donor-acceptor heterojunction between the anode and the cathode, the heterojunction including a donor-like material and an acceptor-like material, wherein at least one of the donor-like material and the acceptor-like material includes a subphthalocyanine, a subporphyrin, and/or a subporphyrazine compound, wherein the subporphyrin or subporphyrazine compound includes boron.
Type:
Grant
Filed:
June 1, 2011
Date of Patent:
August 14, 2012
Assignees:
The Trustees of Princeton University, The Regents of the University of Michigan, The University of Southern California
Inventors:
Barry Rand, Stephen R. Forrest, Kristin L. Mutolo, Elizabeth Mayo, Mark E. Thompson
Abstract: This invention provides a novel class of substituted macrocyclic porphyrin compounds. The compounds are useful as peroxynitrite decomposition catalysts. Pharmaceutical compositions, and methods of making and using the compounds, or a pharmaceutically acceptable salt, hydrate, or prodrug thereof are also described.
Abstract: The invention encompasses novel compositions containing a methylation modifying compound isolated from botanical raw materials, including a fruit of the genus Coffea, and microbial raw materials, methods of making such compositions, and methods of treating or preventing human disease using such compositions. The methylation modifying compound in botanical extracts of the present invention can dramatically increase the level of methylation of PP2A, thus increasing cognitive function, particularly in persons suffering from or prone to developing Alzheimer's disease.
Type:
Grant
Filed:
February 3, 2006
Date of Patent:
July 17, 2012
Assignees:
Signum Biosciences, Inc., Trustees of Princeton University
Inventors:
Jeffry B. Stock, Maxwell Stock, Haoming Gu, Gregory B Stock, Zhu Li, Peter Michael Wolanin
Abstract: Methods of transferring a metal and/or organic layer from a patterned stamp, preferably a soft, elastomeric stamp, to a substrate are provided. The patterned metal or organic layer may be used for example, in a wide range of electronic devices. The present methods are particularly suitable for nanoscale patterning of organic electronic components.
Abstract: Electrodes for dye-sensitized solar cells comprising graphene sheets and at least one binder. The electrodes may be conductive and catalytic counter electrodes. The electrodes may be flexible.
Abstract: A tunable acoustic gradient index of refraction (TAG) lens and system are provided that permit, in one aspect, dynamic selection of the lens output, including dynamic focusing and imaging. The system may include a TAG lens and at least one of a source and a detector of electromagnetic radiation. A controller may be provided in electrical communication with the lens and at least one of the source and detector and may be configured to provide a driving signal to control the index of refraction and to provide a synchronizing signal to time at least one of the source and the detector relative to the driving signal. Thus, the controller is able to specify that the source irradiates the lens (or detector detects the lens output) when a desired refractive index distribution is present within the lens, e.g. when a desired lens output is present.
Type:
Grant
Filed:
February 25, 2008
Date of Patent:
June 5, 2012
Assignee:
Trustees of Princeton University
Inventors:
Craig B. Arnold, Euan McLeod, Alexandre Mermillod-Blondin
Abstract: A supercapacitor or battery electrode containing a modified graphite oxide material, which is a thermally exfoliated graphite oxide with a surface area of from about 300 m2/g to 2600 m2/g.
Type:
Grant
Filed:
September 11, 2008
Date of Patent:
June 5, 2012
Assignee:
The Trustees of Princeton University
Inventors:
Ilhan A. Aksay, Ted Chao-Hung Yeh, Dudley A. Saville, Joy Saville, legal representative
Abstract: Immunogenic compositions and prophylactic or therapeutic vaccines for use in protecting and treating against human cytomegalovirus (CMV) are disclosed. Subunit vaccines comprising a human CMV protein complex comprising pUL128 or pUL130, and nucleic acid vaccines comprising at least one nucleic acid encoding a CMV protein complex comprising pUL128 or pUL130 are described. Also disclosed are therapeutic antibodies reactive against a CMV protein complex comprising pUL128 or pUL130, as well as methods for screening compounds that inhibit CMV infection of epithelial and endothelial cells, methods for immunizing a subject against CMV infection, methods for determining the capability of neutralizing antibodies to inhibit CMV infection of cell types other than fibroblasts, and methods of diminishing an CMV infection.
Abstract: Alterations of certain metabolite concentrations and fluxes that occur in response to viral infection are described. Host cell enzymes in the involved metabolic pathways are selected as targets for intervention; i.e., to restore metabolic flux to disadvantage viral replication, or to further derange metabolic flux resulting in “suicide” of viral-infected cells (but not uninfected cells) in order to limit viral propagation. While any of the enzymes in the relevant metabolic pathway can be selected, pivotal enzymes at key control points in these metabolic pathways are preferred as candidate antiviral drug targets. Inhibitors of these enzymes are used to reverse, or redirect, the effects of the viral infection. Drug candidates are tested for antiviral activity using screening assays in vitro and host cells, as well as in animal models. Animal models are then used to test efficacy of candidate compounds in preventing and treating viral infections. The antiviral activity of enzyme inhibitors is demonstrated.
Type:
Grant
Filed:
June 2, 2008
Date of Patent:
April 17, 2012
Assignee:
The Trustees of Princeton University
Inventors:
Josh Munger, Bryson Bennett, Thomas Shenk, Joshua Rabinowitz
Abstract: A conductive circuit containing a polymer composite, which contains at least one polymer and a modified graphite oxide material, containing thermally exfoliated graphite oxide having a surface area of from about 300 m2/g to 2600 m2/g, and a method of making the same.
Abstract: This invention discloses a process for making nanopanticles of amphiphilic copolymers by flash precipitation. Nanoparticles may be of amphiphilic copolymer alone or may contain an additive target molecule, preferably an organic active. The inclusion of additive target molecules in amphiphilic copolymer nanoparticles can alter their water solubility characteristics, fluid dynamics, and/or stability. Changing an additive target molecule's solubility and stability in an nanoparticle can make a water insoluble compound suitable for pharmaceutical administration as well as specifically target the molecule to a specific area of a patient's body. The process affords the production of nanoparticles at high absolute active content, at high yield, high productivity, and high processing rates while using unusually low amounts of amphiphilic copolymers. Furthermore, the resulting particles exhibit sufficient stability for post processing as desired.
Abstract: A hybrid nanotube, high-performance, dynamically reconfigurable architecture, NATURE, is provided, and a design optimization flow method and system, NanoMap. A run-time reconfigurable architecture is provided by associating a non-volatile universal memory to each logic element to enable cycle-by-cycle reconfiguration and logic folding, while remaining CMOS compatible. Through logic folding, significant logic density improvement and flexibility in performing area-delay tradeoffs are possible. NanoMap incorporates temporal logic folding during the logic mapping, temporal clustering and placement steps. NanoMap provides for automatic selection of a best folding level, and uses force-direct scheduling to balance resources across folding stages. Mapping can thereby target various optimization objectives and user constraints.
Type:
Grant
Filed:
April 19, 2007
Date of Patent:
February 14, 2012
Assignees:
Queen's University at Kingston, Trustees of Princeton University
Abstract: A gas diffusion barrier contains a polymer matrix and a functional graphene which displays no signature of graphite and/or graphite oxide, as determined by X-ray diffraction.
Type:
Grant
Filed:
October 6, 2006
Date of Patent:
February 7, 2012
Assignee:
The Trustees of Princeton University
Inventors:
Robert Prud'Homme, Christopher O'Neil, Bulent Ozbas, Ilhan Aksay, Richard Register, Douglas Adamson
Abstract: A gas storage cylinder or gas storage cylinder liner, formed from a polymer composite, containing at least one polymer and a modified graphite oxide material, which is a thermally exfoliated graphite oxide with a surface area of from about 300 m2/g to 2600 m2/g.
Abstract: A separation medium, such as a chromatography filling or packing, containing a modified graphite oxide material, which is a thermally exfoliated graphite oxide with a surface area of from about 300 m2/g to 2600 m2/g, wherein the thermally exfoliated graphite oxide has a surface that has been at least partially functionalized.
Type:
Grant
Filed:
September 11, 2008
Date of Patent:
January 31, 2012
Assignee:
The Trustees of Princeton University
Inventors:
Robert K. Prud'homme, Ilhan A. Aksay, Margarita Herrera-Alonso
Abstract: The present invention relates to methods and devices for separating particles according to size. More specifically, the present invention relates to a microfluidic method and device for the separation of particles according to size using an array comprising a network of gaps, wherein the field flux from each gap divides unequally into subsequent gaps. In one embodiment, the array comprises an ordered array of obstacles in a microfluidic channel, in which the obstacle array is asymmetric with respect to the direction of an applied field.
Type:
Application
Filed:
July 12, 2011
Publication date:
January 12, 2012
Applicant:
The Trustees of Princeton University
Inventors:
Lotien Richard Huang, James Christopher Sturm, Robert Hamilton Austin