Patents Assigned to Proteus
  • Communication system incorporated in a container
    Patent number: 9198608
    Abstract: The system of the present invention includes a container and an electronic component with a partial power source in the form of dissimilar materials. The container includes a liquid. Upon contact with the liquid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature.
    Type: Grant
    Filed: November 23, 2011
    Date of Patent: December 1, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Hooman Hafezi, David O'Reilly, Patricia Johnson, Zahedeh Hatamkhany, Timothy Robertson, Mark Zdeblick
  • Process for isolating a protein composition and a fat composition from meat trimmings
    Patent number: 9161555
    Abstract: A protein fraction and an oxidation stable fat fraction are recovered from meat trimmings. The trimmings are comminuted, mixed with a food grade acid at pH 3,6 to 4.4 to form a liquid protein fraction and a solid fat fraction. The liquid fraction is mixed with a food grade alkali to precipitate the protein. A myoglobin rich fraction is recovered from the protein fraction and mixed with the precipitated protein.
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: October 20, 2015
    Assignee: Proteus Industries, Inc.
    Inventors: Stephen D. Kelleher, William R. Fielding
  • Communication system incorporated in an ingestible product
    Patent number: 9161707
    Abstract: The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can also be associated with food and communicate data about ingestion of food material to a receiver.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: October 20, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Hooman Hafezi, David O'Reilly, Patricia Johnson, Zahedeh Hatamkhany, Timothy Robertson
  • Ingestible event markers comprising an ingestible component
    Patent number: 9149423
    Abstract: Ingestible event markers comprising an identifier and an ingestible component are provided. The ingestible component may vary, where ingestible components of interest include osmotic ingestible components, liquid capsules, tablets, multi-layered ingestible component and multi-compartment ingestible components. In some instances, the identifier is mechanically stably associated with the ingestible component. Also provided are systems that include the ingestible event markers, as well as methods of using the ingestible event markers.
    Type: Grant
    Filed: May 10, 2010
    Date of Patent: October 6, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Robert Duck, George Savage, Patricia Johnson, Mark Zdeblick, Benedict Costello, Kityee Au-Yeung, Timothy Robertson, Hooman Hafezi
  • Body-associated receiver and method
    Patent number: 9149577
    Abstract: Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: October 6, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Timothy L. Robertson, Fataneh Omidvar, Yashar Behzadi, Lawrence Arne, Kenneth Rowberry, James Hutchison, Robert Leichner, George Savage, Andrew Thompson, Mark Zdeblick, Marc Kreidler, Hooman Hafezi, Robert Duck
  • Fluid transfer port information system
    Patent number: 9125979
    Abstract: Methods are provided for associating a specific one of two or more distinct fluid transfer ports of a patient with a given fluid transfer event of fluid from a parenteral fluid delivery device. Aspects of the methods include establishing a fluid transfer connection between the parenteral fluid delivery device and the patient via one of the two or more distinct fluid transfer ports and transmitting a fluid transfer signal between the parenteral fluid delivery device and a patient associated identifier using the patient's body as a signal conduction medium. Association may result in identification of the fluid transfer port that will be, is being or has been employed for the given fluid transfer event. Also provided are systems for practicing methods of the invention.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: September 8, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Yashar Behzadi, Mark Zdeblick
  • Pharma-informatics system
    Patent number: 9119554
    Abstract: Compositions, systems and methods that allow for the detection of the actual physical delivery of a pharmaceutical agent to a body are provided. Embodiments of the compositions include an identifier and an active agent. The invention finds use in a variety of different applications, including but not limited to, monitoring of therapeutic regimen compliance, tracking the history of pharmaceutical agents, etc.
    Type: Grant
    Filed: November 18, 2010
    Date of Patent: September 1, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Mark Zdeblick, Aleksandr Pikelny, Timothy Robertson, Hooman Hafezi
  • Probablistic pharmacokinetic and pharmacodynamic modeling
    Patent number: 9119918
    Abstract: The subject matter disclosed herein provides a response to a dose of a substance and/or controls the administration of the dose. In one aspect, there is provided a system. The system may include a processor and at least one memory configured to provide a response determinator. The response determinator may receive therapeutic and wellness data. Moreover, the response determinator may determine a response based on the received therapeutic and wellness data. The response may represent a reaction to a substance integrated with an ingestible event marker. The determined response may be provided to, for example, a therapy controller. Related systems, methods, and articles of manufacture are also described.
    Type: Grant
    Filed: May 8, 2013
    Date of Patent: September 1, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Timothy L. Robertson, Yashar Behzadi
  • Ingestible device with pharmaceutical product
    Patent number: 9107806
    Abstract: A system and a manufacturing process are disclosed in accordance with the present invention that protect an electronic device and allows for placement or combination of the device within a pharmaceutical product or capsule. The system includes circuitry and components that can be placed within certain environments. The device includes an assembly including an electronic unit, a flexible membrane secured to the unit, and a protective coating.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: August 18, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Hooman Hafezi, Raymond Schmidt
  • Smart parenteral administration system
    Patent number: 9084566
    Abstract: The invention provides methods and systems for evaluating a fluid transfer event between a parenteral fluid delivery and a patient. The evaluation of the fluid transfer event can be prospective real-time and/or historic, as desired, and take a variety of different formats.
    Type: Grant
    Filed: January 6, 2009
    Date of Patent: July 21, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventor: Mark Zdeblick
  • Active signal processing personal health signal receivers
    Patent number: 9083589
    Abstract: The invention provides a receiver associated with a body, e.g., located inside or within close proximity to a body, configured to receive and decode a signal from an in vivo transmitter which located inside the body. Signal receivers of the invention provide for accurate signal decoding of a low-level signal, even in the presence of significant noise, using a small-scale chip, e.g., where the chip consumes very low power. Also provided are systems that include the receivers, as well as methods of using the same.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: July 14, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Lawrence Arne, Kit Yee Au-Yeung, Kenneth C. Crandall, Timothy Robertson
  • Multi-mode communication ingestible event markers and systems, and methods of using the same
    Patent number: 9060708
    Abstract: Aspects of the invention include multi-mode communication ingestible event marker devices. Ingestible event marker devices of the invention include an ingestible component comprising a conductive communication module and at least one additional non-conductive communication module. The non-conductive communication module may be integrated with the ingestible component or at least a portion or all of the non-conductive communication module may be associated with a packaging component of the ingestible event marker device. Additional aspects of the invention include systems that include the devices and one or more receivers, as well as methods of using the same.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: June 23, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Timothy Robertson, Mark Zdeblick
  • Process for reducing oil and fat in cooked food with pea protein
    Patent number: 9028905
    Abstract: A process for cooking a food in oil and/or fat is provided. A dry pea protein mixture or an aqueous pea protein is added to a food prior to cooking. The amount of oil and/or fat absorbed by the food during cooking is substantially reduced.
    Type: Grant
    Filed: September 12, 2011
    Date of Patent: May 12, 2015
    Assignee: Proteus Industries, Inc.
    Inventors: Wayne S. Saunders, Stephen D. Kelleher, Peter G. Williamson, William R. Fielding
  • Integrated Ingestible Event Marker System with Pharmaceutical Product
    Publication number: 20150112243
    Abstract: A system and method are provided for securing an ingestible electronic device to a pharmaceutical product without damaging the ingestible electronic device. The product includes the ingestible electronic device being placed on the product in accordance with one aspect of the present invention. In accordance with another aspect of the present invention, the ingestible electronic device is placed inside the product. Various embodiments are disclosed in accordance with the present invention for protecting and/or coating of the electronic marker as well as securing the ingestible electronic device onto the product.
    Type: Application
    Filed: May 27, 2014
    Publication date: April 23, 2015
    Applicant: Proteus Digital Health, Inc.
    Inventors: Hooman Hafezi, Robert Duck, Timothy Robertson, Benedict Costello
  • Data gathering system
    Patent number: 9014779
    Abstract: A device for gathering data has first and second electrodes. The first electrode is coupled to a surface of interest, and the second electrode is coupled to “everything else” or “the air”. The first electrode is shielded from the second, and from most sources of parasitic capacitance, by a shield that is driven by an active driver that drives the shield to track, and ideally to match, the instantaneous potential of the electrode. The second electrode is likewise shielded in a similar way from most sources of parasitic capacitance. These shields likewise help to limit the extent to which RFI from the device electronics couples with either of the electrodes. In this way the sensing device achieves a markedly better signal-to-noise ratio at frequency bands of interest.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: April 21, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Mark Zdeblick, James Hutchison, Lawrence Arne
  • Two-wrist data gathering system
    Patent number: 9008761
    Abstract: Sensing is carried out from locations considerably removed from the stomach. Cooperating sensor electronics are placed at each of two wrists of the patient. The potential discomfort and inconvenience of an abdominal patch are reduced or eliminated, and alternative power sources become available.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: April 14, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventor: Mark Zdeblick
  • In-body device with virtual dipole signal amplification
    Patent number: 8961412
    Abstract: Virtual dipole signal amplification for in-body devices, such as implantable and ingestible devices, is provided. Aspects of the in-body deployable antennas of the invention include antennas configured to go from a first configuration to a second configuration following placement in a living body, e.g., via ingestion or implantation. Embodiments of the in-body devices are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: February 24, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Hooman Hafezi, Benedict James Costello, Timothy L. Robertson, Maria Casillas Holen
  • Display screen portion having a graphical user interface for patient monitoring
    Patent number: D733727
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: July 7, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Danielle Schulze Cojuangco, Todd Nathan Rinker, Arna Diana Ionescu
  • Display screen portion having a graphical user interface for patient monitoring
    Patent number: D733760
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: July 7, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Danielle Schulze Cojuangco, Todd Nathan Rinker, Arna Diana Ionescu
  • Display screen portion having a graphical user interface for patient monitoring
    Patent number: D733761
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: July 7, 2015
    Assignee: Proteus Digital Health, Inc.
    Inventors: Danielle Schulze Cojuangco, Todd Nathan Rinker, Arna Diana Ionescu